These Illinois-based companies represent a diverse cross-section of large enterprises in retail, healthcare, hospitality, and manufacturing. Many are well-established global players, with significant employee counts, indicating their scale and long-standing presence in their respective industries. The list includes firms like McDonald's, a global fast-food chain; Walgreens Boots Alliance, an integrated healthcare and retail company; Abbott, a healthcare leader in diagnostics and medical devices; and John Deere, a global leader in agriculture and construction machinery.
A notable pattern among these companies is the concentration of headquarters in the Chicago metropolitan area, with several key players like Hyatt, United Airlines, and Northern Trust based in the city itself. This suggests Chicago continues to be a central hub for major corporate operations across various sectors within Illinois.
| # | Company | Employees | |||
|---|---|---|---|---|---|
| 1 |
McDonald'scorporate.mcdonalds.com
global fast-food restaurant chain operating over 37,000 locations worldwide, serving popular menu items and employing 1.9 million people |
261,219 | |||
| 2 |
Walgreens Boots Alliancewalgreens.com
Integrated healthcare and retail company operating thousands of pharmacy locations, providing medicines, health services, beauty products, and digital convenience globally. |
141,576 | |||
| 3 |
Abbottabbott.com
A global healthcare leader offering life-changing technologies in diagnostics, medical devices, nutrition, and generic medicines, with over 115,000 colleagues serving in 160+ countries |
140,778 | |||
| 4 |
Walgreenswalgreens.com
A leading retail pharmacy offering health and beauty products, with a focus on providing pharmacy services and a seamless omnichannel experience for customers |
90,723 | |||
| 5 | 84,541 | ||||
| 6 |
United Airlinesunited.com
Leading airline with over 90,000 employees focused on customer service, sustainability, and teamwork, currently hiring 15,000 new team members in 2023 |
75,520 | |||
| 7 |
John Deeredeere.com
A global leader in cutting-edge products and technology for agriculture and construction, pushing boundaries for productivity and sustainability worldwide |
55,618 | |||
| 8 |
Allstateallstate.com
This company advocates for peace of mind, builds diverse teams, develops careers, and empowers people and communities through innovation and advocacy |
55,012 | |||
| 9 |
Ulta Beautyulta.com
National retailer offering cosmetics, fragrance, skincare, and hair products from five hundred brands plus in-store salon services including hair, skin, and makeup. |
40,136 | |||
| 10 |
Northern Trustnortherntrust.com
Global provider of innovative wealth management, asset servicing, and investment solutions for institutions, families, and individuals through diverse technology and financial expertise. |
30,965 | |||
| 11 |
US Foodsusfoods.com
Leading foodservice distributor partnering with restaurants & operators to provide innovative food offerings, e-commerce solutions, & technology to help businesses succeed |
24,825 | |||
| 12 |
Discover Financial Servicesdiscover.com
Provider of lending products and payment services enabling merchants, fintech companies, and consumers to access financial solutions and global card acceptance. |
21,937 | |||
| 13 | 21,907 | ||||
| 14 |
Motorola Mobility (a Lenovo Company)motorola.com
Innovative smartphones and accessories are created by a global team, fostering collaboration, creativity, and a commitment to consumer-centric mobile technology innovation |
17,456 | |||
| 15 |
Northwestern Medicinenm.org
Academic medical center combining research, teaching, and patient care with a large workforce across numerous regional locations and top-ranked hospitals. |
16,181 | |||
| 16 |
OSF HealthCareosfhealthcare.org
Integrated health system with hospitals, home care, nursing colleges, digital health services, philanthropic foundation, and healthcare innovation investments. |
12,433 | |||
| 17 |
Advocate Health Careadvocatehealth.com
Integrated nonprofit health system providing clinical innovation, specialized care, extensive research, education, and community benefits across multiple U.S. states. |
11,676 | |||
| 18 | 11,608 | ||||
| 19 |
Jewel-Oscojewelosco.com
A customer-focused grocery store chain in Chicagoland area, providing quality products, friendly service, and great value since 1899 Operating 188 stores |
11,264 | |||
| 20 |
Grouponjob-boards.eu.greenhouse.io
An experiences marketplace offering local deals, live events, and travel options, helping people discover new experiences while assisting businesses in growing |
10,452 | |||
| 21 |
Evernorth Health Servicesevernorth.com
Provider of adaptable pharmacy, care, and benefit services aiming to advance organizations and individuals through connected solutions |
7,188 | |||
| 22 |
Athleticoathletico.com
A leading provider of orthopedic rehabilitation services with over 900 locations nationwide, committed to quality care, patient satisfaction, and community outreach |
6,722 | |||
| 23 |
Grubhubgrubhub.com
Connecting local restaurants with customers nationwide through an easy-to-use platform, delivering authentic cuisine and boosting business revenue. |
6,692 | |||
| 24 |
Crate & Barrelcrateandbarrel.com
Leading home furnishings specialty retailer, offering curated products and custom delivery, with physical stores and online platforms across multiple brands globally. |
6,531 | |||
| 25 |
Chicago Transit Authoritytransitchicago.com
Provides affordable and quality transit services connecting people, jobs, and communities across Chicago and 35 surrounding suburbs daily. |
6,500 | |||
Want more companies than this list?This page shows the largest ones only. Connect to Tamtam to see every company that matches, filter by size, industry or growth, and reach their decision-makers. | |||||
| 26 |
Great Wolf Lodgegreatwolf.com
Indoor water park resorts offering family entertainment, dining, retail, and career growth opportunities with exceptional service and fun environment. |
6,083 | |||
| 27 |
Illinois State Universityillinoisstate.edu
Offering more than 160 fields of study to prepare diverse individuals in becoming informed members of society through collaborative teaching, scholarship, and service |
5,799 | |||
| 28 | 5,564 | ||||
| 29 |
Wintrust Financial Corporationwintrust.com
Provides banking, specialty finance, and wealth management services with a community-focused approach emphasizing integrity and client impact. |
5,374 | |||
| 30 |
National Association of REALTORS庐nar.realtor
America鈥檚 largest trade association representing 15 million real estate industry professionals Promotes diversity, respect, and fosters member-focused culture through social media engagement |
4,551 | |||
| 31 |
BioLife Plasma Servicesbiolifeplasma.com
The company focuses on improving the lives of patients with rare diseases through donor support, career growth opportunities, and comprehensive benefits in a friendly environment |
4,006 | |||
| 32 |
Wyzantwyzant.com
Connecting individuals with over 80,000 tutors in 300+ subjects for tailored 1-to-1 lessons to help achieve academic and career goals |
3,698 | |||
| 33 |
Cooper's Hawk Winery and Restaurantschwinery.com
An elegant tasting room and scratch kitchen restaurant chain with a large wine club, multiple locations, award-winning wines, and celebrity partnerships |
3,605 | |||
| 34 |
Potbelly Sandwich Workspotbelly.com
A neighborhood sandwich shop known for oven-toasted sandwiches, soups, shakes, and cookies, offering fast, friendly service in a welcoming environment |
3,397 | |||
| 35 |
NAV Fund Servicesnavfundservices.com
Top-ranked fund administrator with award-winning service and technology, specializing in cost-effective solutions, digital assets, and emerging managers |
3,061 | |||
| 36 |
Echo Global Logisticsecho.com
Provider of technology-driven freight brokerage and managed transportation solutions across multiple modes, simplifying supply chain management for diverse industries. |
2,874 | |||
| 37 |
Applied Systemswww1.appliedsystems.com
A leading provider of innovative cloud software for the insurance industry, driving transformation through digitization, automation, and new partnerships |
2,813 | |||
| 38 |
UI Healthhospital.uillinois.edu
This academic health enterprise in Illinois offers comprehensive care, education, and research to promote health equity and train healthcare leaders |
2,813 | |||
| 39 |
Chamberlain Groupchamberlaingroup.com
A global leader in intelligent access technology, providing seamless, secure access to homes and businesses through innovative products and software solutions |
2,781 | |||
| 40 | 2,759 | ||||
| 41 |
Robert Bosch Tool Corporation NAboschtools.com
Industry-leading tool corporation manufacturing power tools and accessories, providing innovative, durable, and versatile products through diverse global opportunities for growth and development |
2,525 | |||
| 42 | 2,320 | ||||
| 43 |
Life Fitness / Hammer Strengthlifefitness.com
A global leader in fitness solutions for over 45 years, inspiring healthier lives through cardio, strength, group training, and rehabilitation products |
2,264 | |||
| 44 |
Career Education Corporationperdoceoed.com
Educational services company offering diverse learning formats (online, campus-based, blended) through AIU and CTU with innovative technology and personalized courses |
2,250 | |||
| 45 |
Lettuce Entertain You Restaurantslettuce.com
Owns, manages, and licenses over 110 restaurants across multiple states, offering diverse dining experiences from fast casual to fine dining concepts. |
2,225 | |||
| 46 |
Culligan Internationalculliganinternational.com
Provides advanced water filtration, softening, and treatment systems for homes and businesses through a vast global dealer network. |
2,191 | |||
| 47 |
Advocate Lutheran General Hospitaladvocatehealth.com
A top-ranked teaching hospital in Chicago with specialized pediatric care, trauma center, surgical excellence, stroke care, and nursing excellence |
2,185 | |||
| 48 |
L&W Supplyabcsupplyinteriors.com
A nationwide distributor of gypsum wallboard and building materials, offering seamless service and access to products through local branches |
1,914 | |||
| 49 |
CIBC USus.cibc.com
This company provides a range of banking services including commercial & personal banking, wealth management, and small business financial solutions They are an Equal Housing Lender and Member FDIC |
1,910 | |||
| 50 | 1,866 | ||||
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How this list is built
Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 11, 2026.
More company lists in Illinois
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