# 30 leading critical infrastructure operators in the Rhône department

Tamtam tracks 94 critical infrastructure operators headquartered in the Rhône department. This list ranks the 30 largest by number of employees on LinkedIn, led by Hospices Civils de Lyon - HCL, XPO Logistics Europe and Métropole de Lyon. Their median headcount is 646. Half of them were founded in 1995 or later. The most common headquarters are Lyon (20) and Villeurbanne (3).

These critical infrastructure operators in the Rhône department are mostly large groups in the healthcare, banking, and logistics sectors. Notable entities include Hospices Civils de Lyon, a public university hospital with over 22,000 professionals, and XPO Logistics Europe, offering end-to-end logistics solutions across Europe. Other significant firms are Caisse d'Epargne Rhone Alpes, a prominent regional bank, and Groupe APICIL, a social protection group. CNR (Compagnie Nationale du Rhône) is a major producer of renewable electricity.

A clear pattern among these companies is their long-standing presence, with many founded in the 20th century or earlier, such as Hospices Civils de Lyon (1796) and CIC Lyonnaise de Banque (1865). This indicates a mature and established economic landscape in the region, particularly within essential services.

🇫🇷 Rhône · 30 companies · Updated Nov 11, 2026

| # | Company | Industry | Headquarters | Employees | Founded |
|---|---|---|---|---|---|
| 1 | [Hospices Civils de Lyon - HCL](https://www.tamtam.ai/c/hospices-civils-de-lyon-hcl) (chu-lyon.fr)<br>Public university hospital provides care, education, research, medical innovation, prevention, and health education with over 22,000 professionals across 14 facilities. | Hospitals and Health Care | 🇫🇷 Lyon | 8,220 | 1796 |
| 2 | [XPO Logistics Europe](https://www.tamtam.ai/c/xpo-logistics-europe) (xpo.com)<br>Offers end-to-end logistics solutions, including full-truckload, less-than-truckload, pallet distribution, last-mile delivery, global freight forwarding, and warehousing services across Europe. | Transportation, Logistics, Supply Chain and Storage | 🇫🇷 Lyon | 7,478 | 2011 |
| 3 | [Métropole de Lyon](https://www.tamtam.ai/c/metropole-de-lyon) (grandlyon.com)<br>Manages various public services including mobility, environment, urban planning, social aid, economic development, and cultural activities for 58 communes. | Government Administration | 🇫🇷 Lyon | 3,295 | 2015 |
| 4 | [Caisse d'Epargne Rhone Alpes](https://www.tamtam.ai/c/caisse-d-epargne-rhone-alpes) (caissedepargnerhonealpes.fr)<br>A prominent banking institution in the Rhône-Alpes region serving individuals, businesses, social economy, housing, local authorities, real estate professionals, and protected individuals | Banking | 🇫🇷 Lyon | 2,442 | 2007 |
| 5 | [Banque Populaire Auvergne Rhône Alpes](https://www.tamtam.ai/c/banque-populaire-auvergne-rhone-alpes) (banquepopulaire.fr)<br>A regional bank in Auvergne Rhône Alpes region welcoming candidates, clients, and members They recruit hundreds of employees annually and are active on LinkedIn for recruitment | Banking | 🇫🇷 Lyon | 2,313 | 2016 |
| 6 | [Crédit Agricole Centre-est](https://www.tamtam.ai/c/credit-agricole-centre-est) (ca-centrest.com)<br>A regional banking institution with a cooperative and mutualist foundation, providing various financial services to over 1 million clients and supporting regional economic development | Banking | 🇫🇷 Champagne-au-Mont-d’Or | 2,262 | 1995 |
| 7 | [Santé Cie](https://www.tamtam.ai/c/sante-cie) (santecie.com)<br>Provides home healthcare, dialysis treatment, and urgent care centers across France and Europe, supporting 500,000 patients annually. | Hospitals and Health Care | 🇫🇷 Villeurbanne | 1,979 | 2015 |
| 8 | [Groupe APICIL](https://www.tamtam.ai/c/groupe-apicil) (groupe-apicil.com)<br>A leading French social protection group offering tailored solutions in health, insurance, savings, and retirement, with a focus on client well-being and social responsibility | Insurance | 🇫🇷 Lyon | 1,446 | 1938 |
| 9 | [Centre Léon Bérard](https://www.tamtam.ai/c/centre-leon-berard) (centreleonberard.fr)<br>Specialized cancer hospital and research center providing personalized treatment, innovative therapies, and compassionate care to support patients throughout their illness. | Hospitals and Health Care | 🇫🇷 Lyon | 1,418 | 1923 |
| 10 | [CIC Lyonnaise de Banque](https://www.tamtam.ai/c/cic-lyonnaise-de-banque) (cic.fr)<br>A local bank focusing on client service and supporting the economy with over 160 years of experience, promoting innovation, entrepreneurship, and community involvement | Banking | 🇫🇷 Lyon | 1,417 | 1865 |
| 11 | [CNR (Compagnie Nationale du Rhône)](https://www.tamtam.ai/c/cnr-compagnie-nationale-du-rhone) (tm.fr)<br>French leading producer of 100% renewable electricity, managing the Rhône river for hydroelectricity, navigation, irrigation, and agricultural use, supporting local development and innovation | Electric Power Generation | 🇫🇷 Lyon | 1,256 | 1934 |
| 12 | [Le Vinatier - Psychiatrie Universitaire Lyon Métropole](https://www.tamtam.ai/c/le-vinatier-psychiatrie-universitaire-lyon-metropole) (ch-le-vinatier.fr)<br>Specialized psychiatric hospital providing comprehensive mental health care, treatment, and support services for individuals with mental disorders. | Hospitals and Health Care | 🇫🇷 Bron | 1,246 | 1876 |
| 13 | [Elivie](https://www.tamtam.ai/c/elivie) (elivie.fr)<br>A major provider of home healthcare services in France, assisting over 315,000 patients annually with medical equipment installation and treatment coordination, operating 56 agencies nationwide with 1,500 employees | Home Health Care Services | 🇫🇷 Villeurbanne | 1,161 | 2016 |
| 14 | [Eurofins Biomnis](https://www.tamtam.ai/c/eurofins-biomnis) (eurofins-biomnis.com)<br>A European leader in specialized medical pathology, providing over 2,500 tests including specialized, authorized analyses with a focus on innovation and international development | Medical and Diagnostic Laboratories | 🇫🇷 Lyon | 803 | 1897 |
| 15 | [Hôpital Saint Joseph Saint Luc](https://www.tamtam.ai/c/hopital-saint-joseph-saint-luc) (saintjosephsaintluc.fr)<br>Innovative hospital in Lyon with 360 beds, 1200 employees, and €130M budget Offers comprehensive healthcare services without extra charges, focusing on patient care | Hospitals and Health Care | 🇫🇷 Lyon | 646 | 2002 |
| 16 | [ARHM (soins - accompagnement - recherche)](https://www.tamtam.ai/c/arhm-soins-accompagnement-recherche) (fondationarhm.fr)<br>Management of psychiatric, mental and physical disability, and addiction care facilities serving over 16,000 patients annually in Lyon region. | Hospitals and Health Care | 🇫🇷 Lyon | 643 | 1950 |
| 17 | [Médipôle Lyon-Villeurbanne](https://www.tamtam.ai/c/medipole-lyon-villeurbanne) (medipolelyonvilleurbanne.fr)<br>This private hospital pole combines two entities, offering diverse medical and surgical specialties across medicine, surgery, obstetrics, and rehabilitation care. | Hospitals and Health Care | 🇫🇷 Villeurbanne | 486 |  |
| 18 | [Eurofins Biologie Médicale](https://www.tamtam.ai/c/eurofins-biologie-medicale) (eurofins.com)<br>Network of over 280 medical biology laboratories in France providing quality patient care, early diagnostics, and innovative medical testing services. | Medical and Diagnostic Laboratories | 🇫🇷 Lyon | 412 |  |
| 19 | [Hôpitaux Nord-Ouest](https://www.tamtam.ai/c/hopitaux-nord-ouest) (hno.fr)<br>Comprehensive healthcare services across five hospitals and ten care homes, providing consultations, hospitalizations, and continuous public health coverage. | Hospitals and Health Care | 🇫🇷 Villefranche-sur-Saône | 407 |  |
| 20 | [Oxance](https://www.tamtam.ai/c/oxance) (oxance.fr)<br>Major non-profit health provider in France, offering medical, dental, nursing, social care, optical, and audiology services across 130 establishments for accessible, quality care. | Hospitals and Health Care | 🇫🇷 Lyon | 354 | 2018 |
| 21 | [HOPITAL PRIVE JEAN MERMOZ](https://www.tamtam.ai/c/hopital-prive-jean-mermoz) (hopital-prive-jean-mermoz-lyon.ramsaysante.fr)<br>Hospital and Health Care company in Lyon, France, providing medical services from its location on Av Jean Mermoz in Rhone-Alpes | Hospitals and Health Care | 🇫🇷 Lyon | 353 | 2008 |
| 22 | [Infirmerie Protestante de Lyon](https://www.tamtam.ai/c/infirmerie-protestante-de-lyon) (infirmerie-protestante.com)<br>Non-profit healthcare institution in Lyon specializing in cardiovascular, cancer, orthopedic, ophthalmology surgeries, and internal medicine services. | Hospitals and Health Care | 🇫🇷 Caluire-et-Cuire | 346 | 1844 |
| 23 | [Clinique du Parc Lyon - ELSAN](https://www.tamtam.ai/c/clinique-du-parc-lyon-elsan) (elsan.care)<br>Specialized surgical care center in Lyon offering orthopedic, plastic, ophthalmologic, neuro, bariatric surgeries with advanced imaging and rehabilitation services. | Hospitals and Health Care | 🇫🇷 Lyon | 295 |  |
| 24 | [Clinique de la Sauvegarde](https://www.tamtam.ai/c/clinique-de-la-sauvegarde) (ramsaysante.fr)<br>A hospital and health care company based in Lyon, France, specializing in providing medical services to patients in need of care | Hospitals and Health Care | 🇫🇷 Lyon | 289 | 2008 |
| 25 | [Crédit Mutuel du Sud-Est](https://www.tamtam.ai/c/credit-mutuel-du-sud-est) (creditmutuel.fr)<br>Mutualist regional bank serving 650,000 clients with 143 branches, supporting local economy, social values, and community partnerships. | Banking | 🇫🇷 Lyon | 288 | 1969 |
| 26 | [Centre Hospitalier Saint Cyr au Mont d'Or](https://www.tamtam.ai/c/centre-hospitalier-saint-cyr-au-mont-d-or) (ch-st-cyr69.fr)<br>Public mental health institution providing prevention, diagnosis, treatment, rehabilitation, and social reintegration across a large regional territory. | Hospitals and Health Care | 🇫🇷 Saint-Cyr-au-Mont-d'Or | 271 | 1972 |
| 27 | [IMADIS Groupe](https://www.tamtam.ai/c/imadis-groupe) (imadis-groupe.fr)<br>Providing remote radiology solutions supporting healthcare facilities across metropolitan France and overseas, ensuring continuous, equal access to imaging diagnostics. | Medical Practices | 🇫🇷 Lyon | 260 | 2008 |
| 28 | [SYTRAL](https://www.tamtam.ai/c/sytral) (sytral-mobilites.fr)<br>The company aims to provide the best transport network for residents through the development of public transportation services and infrastructure in Lyon | Government Administration | 🇫🇷 Lyon | 253 | 1985 |
| 29 | [UGECAM Rhône-Alpes](https://www.tamtam.ai/c/ugecam-rhone-alpes) (groupe-ugecam.fr)<br>Management of healthcare and medico-social facilities providing rehabilitation, medical care, and social support with multidisciplinary professional teams. | Hospitals and Health Care | 🇫🇷 Saint Didier au Mont d'Or | 253 | 2000 |
| 30 | [Soins et Santé Groupe](https://www.tamtam.ai/c/soins-et-sante-groupe) (soinsetsante.org)<br>Specializing in home care for elderly, sick, and disabled individuals, the association provides a range of coordinated services in the Lyon region for over 50 years | Hospitals and Health Care | 🇫🇷 Rillieux-la-Pape | 228 | 1972 |

## How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 11, 2026.

## More company lists in the Rhône department

- [The largest companies in the Rhône department](https://www.tamtam.ai/l/largest-companies-rhone) (4,813)
- [Multinational companies in the Rhône department](https://www.tamtam.ai/l/multinational-companies-rhone) (577)
- [Companies with in-house R&D in the Rhône department](https://www.tamtam.ai/l/r-and-d-companies-rhone) (509)
- [Professional services firms in the Rhône department](https://www.tamtam.ai/l/professional-services-firms-rhone) (400)
- [Manufacturers in the Rhône department](https://www.tamtam.ai/l/manufacturers-rhone) (322)
- [Retail chains in the Rhône department](https://www.tamtam.ai/l/retail-chains-rhone) (302)
- [IT services companies in the Rhône department](https://www.tamtam.ai/l/it-services-companies-rhone) (286)
- [SaaS companies in the Rhône department](https://www.tamtam.ai/l/saas-companies-rhone) (284)
- [Software Development companies in the Rhône department](https://www.tamtam.ai/l/software-development-companies-rhone) (264)
- [IT Services and IT Consulting companies in the Rhône department](https://www.tamtam.ai/l/it-services-and-it-consulting-companies-rhone) (253)
- [Hardware manufacturers in the Rhône department](https://www.tamtam.ai/l/hardware-companies-rhone) (243)
- [Consulting firms in the Rhône department](https://www.tamtam.ai/l/consulting-firms-rhone) (242)
- [Business Consulting and Services companies in the Rhône department](https://www.tamtam.ai/l/business-consulting-and-services-companies-rhone) (219)
- [Distributors and wholesalers in the Rhône department](https://www.tamtam.ai/l/distributors-and-wholesalers-rhone) (185)
- [Higher Education companies in the Rhône department](https://www.tamtam.ai/l/higher-education-companies-rhone) (155)
- [Education providers in the Rhône department](https://www.tamtam.ai/l/education-companies-rhone) (154)
- [Law Practice companies in the Rhône department](https://www.tamtam.ai/l/law-practice-companies-rhone) (152)
- [Real Estate companies in the Rhône department](https://www.tamtam.ai/l/real-estate-companies-rhone) (151)
- [Family-owned companies in the Rhône department](https://www.tamtam.ai/l/family-owned-companies-rhone) (149)
- [Subscription businesses in the Rhône department](https://www.tamtam.ai/l/subscription-businesses-rhone) (149)
- [Construction companies in the Rhône department](https://www.tamtam.ai/l/construction-companies-rhone) (140)
- [Pharmaceutical companies in the Rhône department](https://www.tamtam.ai/l/pharmaceutical-companies-rhone) (134)
- [Financial services firms in the Rhône department](https://www.tamtam.ai/l/financial-services-firms-rhone) (132)
- [Advertising Services companies in the Rhône department](https://www.tamtam.ai/l/advertising-services-companies-rhone) (126)

## The same list elsewhere in France

- [Critical infrastructure operators in France](https://www.tamtam.ai/l/critical-infrastructure-operators-france) (2,721)
- [Critical infrastructure operators in Île-de-France](https://www.tamtam.ai/l/critical-infrastructure-operators-ile-de-france) (780)
- [Critical infrastructure operators in Auvergne-Rhône-Alpes](https://www.tamtam.ai/l/critical-infrastructure-operators-auvergne-rhone-alpes) (299)
- [Critical infrastructure operators in Grand Est](https://www.tamtam.ai/l/critical-infrastructure-operators-grand-est) (257)
- [Critical infrastructure operators in Occitanie](https://www.tamtam.ai/l/critical-infrastructure-operators-occitanie) (216)
- [Critical infrastructure operators in Nouvelle-Aquitaine](https://www.tamtam.ai/l/critical-infrastructure-operators-nouvelle-aquitaine) (209)
- [Critical infrastructure operators in Provence-Alpes-Côte d'Azur](https://www.tamtam.ai/l/critical-infrastructure-operators-provence-alpes-cote-dazur) (200)
- [Critical infrastructure operators in Hauts-de-France](https://www.tamtam.ai/l/critical-infrastructure-operators-hauts-de-france) (174)
- [Critical infrastructure operators in the Hauts-de-Seine department](https://www.tamtam.ai/l/critical-infrastructure-operators-hauts-de-seine) (169)
- [Critical infrastructure operators in Pays de la Loire](https://www.tamtam.ai/l/critical-infrastructure-operators-pays-de-la-loire) (127)
- [Critical infrastructure operators in Brittany](https://www.tamtam.ai/l/critical-infrastructure-operators-brittany) (120)
- [Critical infrastructure operators in Normandy](https://www.tamtam.ai/l/critical-infrastructure-operators-normandy) (103)
- [Critical infrastructure operators in the Bouches-du-Rhône department](https://www.tamtam.ai/l/critical-infrastructure-operators-bouches-du-rhone) (98)
- [Critical infrastructure operators in Centre-Val de Loire](https://www.tamtam.ai/l/critical-infrastructure-operators-centre-val-de-loire) (87)
- [Critical infrastructure operators in the Nord department](https://www.tamtam.ai/l/critical-infrastructure-operators-nord) (87)
- [Critical infrastructure operators in Bourgogne-Franche-Comté](https://www.tamtam.ai/l/critical-infrastructure-operators-bourgogne-franche-comte) (76)
- [Critical infrastructure operators in the Haute-Garonne department](https://www.tamtam.ai/l/critical-infrastructure-operators-haute-garonne) (64)
- [Critical infrastructure operators in the Gironde department](https://www.tamtam.ai/l/critical-infrastructure-operators-gironde) (63)
- [Critical infrastructure operators in the Loire-Atlantique department](https://www.tamtam.ai/l/critical-infrastructure-operators-loire-atlantique) (59)
- [Critical infrastructure operators in the Hérault department](https://www.tamtam.ai/l/critical-infrastructure-operators-herault) (57)
- [Critical infrastructure operators in the Seine-Saint-Denis department](https://www.tamtam.ai/l/critical-infrastructure-operators-seine-saint-denis) (53)
- [Critical infrastructure operators in the Seine-Maritime department](https://www.tamtam.ai/l/critical-infrastructure-operators-seine-maritime) (46)
- [Critical infrastructure operators in the Ille-et-Vilaine department](https://www.tamtam.ai/l/critical-infrastructure-operators-ille-et-vilaine) (45)
- [Critical infrastructure operators in Paris](https://www.tamtam.ai/l/critical-infrastructure-operators-paris) (331)

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Source: https://www.tamtam.ai/l/critical-infrastructure-operators-rhone