# Healthtech companies headquartered in California

Tamtam tracks 152 healthtech companies headquartered in California. This list ranks the 50 largest by number of employees on LinkedIn, led by Genentech, Edwards Lifesciences and VSP Vision. Their median headcount is 1,389. Half of them were founded in 2013 or later. The most common headquarters are San Francisco (16), Palo Alto (4) and Irvine (3).

These California companies are primarily in biotechnology research, medical equipment manufacturing, and healthcare services. They range from established firms like Genentech, a science company finding solutions for difficult-to-treat conditions, and Edwards Lifesciences, which develops structural heart technologies, to newer companies like Lyra Health, providing AI-driven mental health benefits, and Clipboard, a platform connecting healthcare facilities with professionals for shifts. Many of these companies focus on developing innovative solutions in specialized medical fields.

The headquarters of these companies are spread across California, with notable clusters in the San Francisco Bay Area (South San Francisco, Hercules, Palo Alto) and Southern California (Irvine, San Diego, Los Angeles). This geographic distribution highlights a broad presence of healthtech innovation throughout the state. Several companies, such as Bio-Rad Laboratories, founded in 1952, and VSP Vision, founded in 1955, have long histories, while others like Envista Holdings Corporation (2019) are more recent.

🇺🇸 California · 50 companies · Updated Nov 12, 2026

| # | Company | Industry | Headquarters | Employees | Founded |
|---|---|---|---|---|---|
| 1 | [Genentech](https://www.tamtam.ai/c/genentech) (gene.com)<br>A cutting-edge science company passionate about finding innovative solutions for difficult-to-treat conditions, providing global access to life-changing medicines | Biotechnology Research | 🇺🇸 South San Francisco | 18,287 | 1976 |
| 2 | [Edwards Lifesciences](https://www.tamtam.ai/c/edwards-lifesciences) (edwards.com)<br>Develops breakthrough structural heart technologies and medical devices for patients, partnering with clinicians to improve lives globally across over 100 countries. | Medical Equipment Manufacturing | 🇺🇸 Irvine | 14,148 | 1958 |
| 3 | [VSP Vision](https://www.tamtam.ai/c/vsp-vision) (vspvision.com)<br>A global company dedicated to improving vision and providing healthcare solutions through innovative products, programs, and services, with a focus on diversity and charitable giving | Hospitals and Health Care | 🇺🇸 Rancho Cordova | 10,506 | 1955 |
| 4 | [Bio-Rad Laboratories](https://www.tamtam.ai/c/bio-rad-laboratories) (bio-rad.com)<br>Development and supply of innovative products for life science research and medical diagnostics, enhancing discovery and clinical results worldwide. | Biotechnology Research | 🇺🇸 Hercules | 9,416 | 1952 |
| 5 | [Resmed](https://www.tamtam.ai/c/resmed) (resmed.com.br)<br>The company pioneers innovative medical devices and software platforms to treat chronic diseases, improve quality of life, and reduce healthcare costs globally | Medical Equipment Manufacturing | 🇺🇸 San Diego | 9,180 | 1989 |
| 6 | [Dexcom](https://www.tamtam.ai/c/dexcom) (dexcom.com)<br>A leader in continuous glucose monitoring technology, empowering individuals with diabetes to control their health and pursue their dreams | Medical Equipment Manufacturing | 🇺🇸 San Diego | 8,997 | 1999 |
| 7 | [Varian](https://www.tamtam.ai/c/varian) (cancercare.siemens-healthineers.com)<br>Development and delivery of advanced imaging, radiation therapy, software, and services supporting the entire cancer care journey globally. | Medical Equipment Manufacturing | 🇺🇸 Palo Alto | 8,395 |  |
| 8 | [Internet Brands](https://www.tamtam.ai/c/internet-brands) (internetbrands.com)<br>An online media and technology company in Automotive, Health, Legal, and Home/Travel industries, providing web solutions, media websites, and web presence software products | Software Development | 🇺🇸 El Segundo | 7,007 | 1998 |
| 9 | [RadNet](https://www.tamtam.ai/c/radnet) (radnet.com)<br>A leading provider of diagnostic imaging services with 370+ locations in core markets like California, offering services through a network of 9,000 employees | Hospitals and Health Care | 🇺🇸 Los Angeles | 5,667 | 1984 |
| 10 | [Infinx](https://www.tamtam.ai/c/infinx) (infinx.com)<br>Innovative healthcare company offering scalable prior authorization and revenue cycle management solutions, using AI-driven software and billing specialists to optimize revenue capture | Hospitals and Health Care | 🇺🇸 Cupertino | 5,195 | 2012 |
| 11 | [BetterHelp](https://www.tamtam.ai/c/betterhelp) (betterhelp.com)<br>Provides online therapy sessions through video, voice, chat, and messaging with licensed therapists to support mental health improvement. | Mental Health Care | 🇺🇸 Mountain View | 4,101 | 2013 |
| 12 | [Clipboard](https://www.tamtam.ai/c/clipboard) (clipboardworks.com)<br>Platform connecting healthcare facilities and schools with local professionals for unfilled shifts, improving care and offering flexible, higher-paying work. | Internet Marketplace Platforms | 🇺🇸 San Francisco | 3,716 | 2016 |
| 13 | [Episource](https://www.tamtam.ai/c/episource) (episource.com)<br>A leading provider of risk adjustment services, software, and solutions for health plans and provider groups, specializing in end-to-end solutions | IT Services and IT Consulting | 🇺🇸 Gardena | 2,922 | 2006 |
| 14 | [Lyra Health](https://www.tamtam.ai/c/lyra-health) (lyrahealth.com)<br>Provider of AI-driven mental health benefits and personalized support, connecting employees to exclusive providers and tools for recovery. | Mental Health Care | 🇺🇸 Burlingame | 2,872 | 2015 |
| 15 | [Envista Holdings Corporation](https://www.tamtam.ai/c/envista-holdings-corporation) (envistaco.com)<br>Partners with dental professionals, providing industry-leading products, solutions, and technology for diagnosing, treating, preventing dental conditions, and improving smile aesthetics globally. | Medical Equipment Manufacturing | 🇺🇸 Brea | 2,210 | 2019 |
| 16 | [Personify Health](https://www.tamtam.ai/c/personify-health) (personifyhealth.com)<br>A personalized health platform offering health plan administration, wellbeing solutions, and health navigation services to empower individuals and optimize investments for businesses | Health and Human Services | 🇺🇸 Fresno | 2,139 | 2023 |
| 17 | [hims & hers](https://www.tamtam.ai/c/hims-and-hers) (bit.ly)<br>A multi-specialty telehealth platform connecting consumers to licensed healthcare professionals for various conditions like sexual health, hair care, mental health, and more | Wellness and Fitness Services | 🇺🇸 San Francisco | 2,022 | 2017 |
| 18 | [Saama](https://www.tamtam.ai/c/saama) (saama.com)<br>Develops AI-driven life science solutions accelerating therapy delivery, enhancing clinical and commercial operations, improving patient outcomes globally. | Software Development | 🇺🇸 Campbell | 1,884 |  |
| 19 | [iRhythm Technologies, Inc.](https://www.tamtam.ai/c/irhythm-technologies-inc) (irhythm.com)<br>A digital health company using wearable biosensors and data analytics to detect, predict, and prevent disease, with a focus on patient care and innovation | Medical Equipment Manufacturing | 🇺🇸 San Francisco | 1,874 | 2006 |
| 20 | [Included Health](https://www.tamtam.ai/c/included-health) (includedhealth.com)<br>Integrated virtual care and navigation company breaking down barriers to provide high-quality healthcare for all, offering personalized care guidance and access | Hospitals and Health Care | 🇺🇸 San Francisco | 1,732 |  |
| 21 | [Hinge Health](https://www.tamtam.ai/c/hinge-health) (hingehealth.com)<br>AI-driven musculoskeletal care combining wearable technology and expert clinicians to deliver personalized, evidence-based treatment improving outcomes and reducing costs. | Software Development | 🇺🇸 San Francisco | 1,665 | 2014 |
| 22 | [Commure](https://www.tamtam.ai/c/commure) (commure.com)<br>Innovative technologies enhancing healthcare workforce, solving industry challenges, and catalyzing a vibrant health ecosystem for hospitals and health systems | Software Development | 🇺🇸 Mountain View | 1,577 |  |
| 23 | [Headspace](https://www.tamtam.ai/c/headspace-san-francisco) (headspace.com)<br>provides evidence-based mental health support combining clinical care and technology to offer personalized, accessible lifelong mental health assistance worldwide | Mental Health Care | 🇺🇸 San Francisco | 1,560 |  |
| 24 | [ŌURA](https://www.tamtam.ai/c/oura) (ouraring.com)<br>A fast-growing startup based in Finland, Oura helps people track sleep and activity with their Oura Ring and app, empowering users to improve their health and well-being | Wellness and Fitness Services | 🇺🇸 San Francisco | 1,428 | 2013 |
| 25 | [Doctor On Demand](https://www.tamtam.ai/c/doctor-on-demand) (includedhealth.com)<br>Integrated virtual care and navigation to raise healthcare standards, providing high-quality, personalized care for all health needs and journey stages | Hospitals and Health Care | 🇺🇸 San Francisco | 1,389 | 2013 |
| 26 | [Medely](https://www.tamtam.ai/c/medely) (medely.com)<br>Medely is a healthcare labor marketplace connecting professionals with high-paying jobs and providing facilities with workforce management tools Join the team revolutionizing healthcare | Hospitals and Health Care | 🇺🇸 Santa Monica | 1,344 | 2015 |
| 27 | [Advantmed](https://www.tamtam.ai/c/advantmed) (advantmed.com)<br>A healthcare information management company offering solutions to optimize revenue and quality outcomes for health plans and Managed Care Organizations | Hospitals and Health Care | 🇺🇸 Irvine | 1,294 | 2005 |
| 28 | [Honor](https://www.tamtam.ai/c/honor-san-francisco) (honorcare.com)<br>This company revolutionizes in-home care for seniors by combining expertise in workforce management, technology, and personalized care, partnering with home care agencies nationwide | Hospitals and Health Care | 🇺🇸 San Francisco | 1,193 |  |
| 29 | [Carbon Health](https://www.tamtam.ai/c/carbon-health) (carbonhealth.com)<br>A tech-enabled healthcare company with a human-centered approach, aiming to break down traditional healthcare barriers and provide accessible personalized care | Hospitals and Health Care | 🇺🇸 Sunnyvale | 1,090 | 2015 |
| 30 | [GoodRx](https://www.tamtam.ai/c/goodrx) (blocked.goodrx.com)<br>The company is focused on providing affordable and convenient healthcare solutions for all Americans through technology, savings cards, and an app | Hospitals and Health Care | 🇺🇸 Santa Monica | 1,087 | 2011 |
| 31 | [Tebra](https://www.tamtam.ai/c/tebra) (tebra.com)<br>Unified EHR, billing, and patient experience tools for independent medical practices and billing companies to streamline operations and growth. | Software Development | 🇺🇸 Corona del Mar | 1,069 |  |
| 32 | [Private Access, Inc.](https://www.tamtam.ai/c/private-access-inc) (privateaccess.com)<br>Developing web applications to solve privacy issues in medical research, facilitating secure sharing of confidential records & accelerating research with dynamic electronic consent management | Software Development | 🇺🇸 Irvine | 1,031 | 2006 |
| 33 | [Solace](https://www.tamtam.ai/c/solace-redwood-city) (solace.health)<br>A marketplace connecting individuals with health advocates to empower them in navigating and taking control of their personal health decisions | Hospitals and Health Care | 🇺🇸 Redwood City | 1,008 | 2022 |
| 34 | [Omada Health](https://www.tamtam.ai/c/omada-health) (omadahealth.com)<br>Virtual-first healthcare provider offering personalized interventions for chronic conditions, using clinical protocols and behavior science to achieve long-term health improvements with evidence-based programs | Hospitals and Health Care | 🇺🇸 San Francisco | 988 | 2011 |
| 35 | [Ambry Genetics](https://www.tamtam.ai/c/ambry-genetics) (ambrygen.com)<br>A leading clinical genomic diagnostic company with the largest genetic sequencing lab worldwide, offering precision medicine solutions and partnering with non-profit organizations | Biotechnology Research | 🇺🇸 Aliso Viejo | 977 | 1999 |
| 36 | [Machinify](https://www.tamtam.ai/c/machinify) (machinify.com)<br>A healthcare software company uses machine learning and data analytics to improve outcomes and drive down costs in the industry | Software Development | 🇺🇸 Palo Alto | 937 | 2016 |
| 37 | [Doximity](https://www.tamtam.ai/c/doximity) (doximity.com)<br>A digital platform connecting over 80% of US physicians, providing tools for collaboration, staying updated, managing careers, and conducting virtual patient visits | Software Development | 🇺🇸 San Francisco | 914 | 2010 |
| 38 | [Modern Health](https://www.tamtam.ai/c/modern-health) (modernhealth.com)<br>Global workforce mental health platform, employee benefit. Provides evidence-based coaching, therapy, group support, digital programs. Fast access to culturally responsive care. | Mental Health Care | 🇺🇸 San Francisco | 905 | 2017 |
| 39 | [Trusted Health](https://www.tamtam.ai/c/trusted-health) (trustedhealth.com)<br>A leading labor marketplace and workforce management platform for healthcare, connecting nurses to job opportunities and offering full employer-of-record services | Software Development | 🇺🇸 San Francisco | 893 | 2017 |
| 40 | [iSpace, Inc.](https://www.tamtam.ai/c/ispace-inc-el-segundo) (ispace.com)<br>A global services company specializing in IT, BPO, and healthcare solutions, driving innovation and delivering outcomes for Fortune 1000 clients | IT Services and IT Consulting | 🇺🇸 El Segundo | 893 | 2000 |
| 41 | [Astrana Health](https://www.tamtam.ai/c/astrana-health) (astranahealth.com)<br>Technology-powered healthcare company enabling providers to deliver accessible, high-quality, and high-value care through an integrated platform for value-based arrangements | Hospitals and Health Care | 🇺🇸 Alhambra | 892 |  |
| 42 | [Best Doctors](https://www.tamtam.ai/c/best-doctors) (bestdoctors.com)<br>A global expert medical service providing access to a network of top specialists for diagnosis, treatment plans, and healthcare cost reduction | Hospitals and Health Care | 🇺🇸 Toronto | 857 |  |
| 43 | [Equip](https://www.tamtam.ai/c/equip) (equip.health)<br>The company provides virtual care teams and gold-standard treatment at home for families seeking lasting recovery from eating disorders | Mental Health Care | 🇺🇸 San Diego | 842 | 2019 |
| 44 | [Heartflow](https://www.tamtam.ai/c/heartflow) (heartflow.com)<br>Advanced AI technology creating personalized 3D heart models from CT scans to improve diagnosis and treatment of coronary artery disease. | Medical Equipment Manufacturing | 🇺🇸 San Francisco | 841 | 2010 |
| 45 | [CareDx, Inc.](https://www.tamtam.ai/c/caredx-inc) (caredx.com)<br>Innovative company specializing in non-invasive diagnostics for organ transplant patients, offering surveillance and pre-transplant solutions for kidney and heart transplants | Biotechnology Research | 🇺🇸 Brisbane | 834 |  |
| 46 | [Collective Health](https://www.tamtam.ai/c/collective-health) (collectivehealth.com)<br>Integrated health benefits platform streamlining delivery, improving member experience, and reducing costs for employees and companies to navigate and pay for healthcare | Hospitals and Health Care | 🇺🇸 San Francisco | 811 | 2013 |
| 47 | [Transcarent](https://www.tamtam.ai/c/transcarent) (transcarent.com)<br>Streamlines healthcare access with personalized app & on-demand care team Guides members to high-quality, affordable care while improving quality & reducing costs | Hospitals and Health Care | 🇺🇸 San Francisco | 810 | 2020 |
| 48 | [Sante](https://www.tamtam.ai/c/sante-palo-alto) (santeapp.com)<br>A Silicon Valley-based mHealth startup is revolutionizing healthcare technology Stay tuned for exciting updates! | Wellness and Fitness Services | 🇺🇸 Palo Alto | 765 |  |
| 49 | [Twin Health](https://www.tamtam.ai/c/twin-health) (twinhealth.com)<br>The company combines medical science and digital twin technology to personalize care for chronic metabolic diseases through individualized guidance and support | Hospitals and Health Care | 🇺🇸 Menlo Park | 755 | 2018 |
| 50 | [7 Cups](https://www.tamtam.ai/c/7-cups) (7cups.com)<br>A global platform providing emotional support and mental health services in multiple languages to millions of people worldwide | Wellness and Fitness Services | 🇺🇸 Palo Alto | 747 | 2013 |

## How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 12, 2026.

## More company lists in California

- [The largest companies in California](https://www.tamtam.ai/l/largest-companies-california) (15,264)
- [Multinational companies in California](https://www.tamtam.ai/l/multinational-companies-california) (2,591)
- [SaaS companies in California](https://www.tamtam.ai/l/saas-companies-california) (1,854)
- [Software Development companies in California](https://www.tamtam.ai/l/software-development-companies-california) (1,649)
- [AI companies in California](https://www.tamtam.ai/l/ai-companies-california) (1,296)
- [Companies with in-house R&D in California](https://www.tamtam.ai/l/r-and-d-companies-california) (1,275)
- [Manufacturers in California](https://www.tamtam.ai/l/manufacturers-california) (1,066)
- [Hardware manufacturers in California](https://www.tamtam.ai/l/hardware-companies-california) (985)
- [IT Services and IT Consulting companies in California](https://www.tamtam.ai/l/it-services-and-it-consulting-companies-california) (968)
- [Education providers in California](https://www.tamtam.ai/l/education-companies-california-united-states) (950)
- [Subscription businesses in California](https://www.tamtam.ai/l/subscription-businesses-california) (939)
- [Venture capital and private equity firms in California](https://www.tamtam.ai/l/vc-and-private-equity-firms-california) (917)
- [Professional services firms in California](https://www.tamtam.ai/l/professional-services-firms-california) (880)
- [Companies with a mobile app in California](https://www.tamtam.ai/l/companies-with-mobile-app-california) (827)
- [Retail chains in California](https://www.tamtam.ai/l/retail-chains-california) (803)
- [IT services companies in California](https://www.tamtam.ai/l/it-services-companies-california) (796)
- [Venture Capital and Private Equity Principals companies in California](https://www.tamtam.ai/l/venture-capital-and-private-equity-principals-companies-california) (731)
- [Financial services firms in California](https://www.tamtam.ai/l/financial-services-firms-california) (711)
- [Financial Services companies in California](https://www.tamtam.ai/l/financial-services-companies-california) (642)
- [Healthcare providers in California](https://www.tamtam.ai/l/healthcare-providers-california) (569)
- [AI-native companies in California](https://www.tamtam.ai/l/ai-native-companies-california) (561)
- [Hospitals and Health Care companies in California](https://www.tamtam.ai/l/hospitals-and-health-care-companies-california) (555)
- [Consulting firms in California](https://www.tamtam.ai/l/consulting-firms-california) (551)
- [Public sector organisations in California](https://www.tamtam.ai/l/public-sector-organisations-california) (535)

## The same list elsewhere in United States

- [Healthtech companies in the United States](https://www.tamtam.ai/l/healthtech-companies-united-states) (792)
- [Healthtech companies in New York State](https://www.tamtam.ai/l/healthtech-companies-new-york-state) (101)
- [Healthtech companies in Texas](https://www.tamtam.ai/l/healthtech-companies-texas) (60)
- [Healthtech companies in Massachusetts](https://www.tamtam.ai/l/healthtech-companies-massachusetts) (53)
- [Healthtech companies in Florida](https://www.tamtam.ai/l/healthtech-companies-florida) (47)
- [Healthtech companies in Pennsylvania](https://www.tamtam.ai/l/healthtech-companies-pennsylvania) (34)
- [Healthtech companies in Illinois](https://www.tamtam.ai/l/healthtech-companies-illinois) (30)
- [Healthtech companies in New Jersey](https://www.tamtam.ai/l/healthtech-companies-new-jersey) (26)
- [Healthtech companies in New York](https://www.tamtam.ai/l/healthtech-companies-new-york) (91)
- [Healthtech companies in San Francisco](https://www.tamtam.ai/l/healthtech-companies-san-francisco) (53)

## The same list elsewhere

- [Healthtech companies in the world](https://www.tamtam.ai/l/healthtech-companies-in-the-world) (1,953)

---

Source: https://www.tamtam.ai/l/healthtech-companies-california