The 100 largest companies in Columbia (2026 list)

#	Company	Industry	Headquarters	Employees	Founded
1	University of Missouri System umsystem.edu A prestigious public research institution in Missouri, promoting education, research, and service to serve the state, nation, and beyond	Higher Education	🇺🇸 Columbia	26,615	n/a
2	Amergis Healthcare Staffing amergis.com Healthcare staffing agency offering opportunities and solutions for various healthcare professionals and organizations with a personalized approach and exceptional service	Staffing and Recruiting	🇺🇸 Columbia	19,829	1988
3	Maxim Healthcare Staffing maximhealthcare.com A national healthcare staffing agency connecting top professionals with various partners, offering career opportunities in nursing, allied health, locum tenens, and more	Staffing and Recruiting	🇺🇸 Columbia	16,382	1988
4	University of Missouri-Columbia missouri.edu State-supported research university providing education, advancing arts, sciences, and professions, focusing on public service and economic development.	Higher Education	🇺🇸 Columbia	14,879	n/a
5	University of South Carolina sc.edu A globally recognized research university offering 324 degree programs, top-tier research, community engagement, and numerous nationally ranked programs in South Carolina	Higher Education	🇺🇸 Columbia	13,337	1801
6	McCausland College of Arts and Sciences sc.edu Official university page for College of Arts and Sciences at University of South Carolina Connect with alumni, faculty, and staff for updates	Higher Education	🇺🇸 Columbia	12,889	1801
7	MedStar Health medstarhealth.org Not-for-profit health system providing medical care, education, research, and training with a patient-first approach in Maryland and Washington, D.C.	Hospitals and Health Care	🇺🇸 Columbia	10,037	1999
8	Colonial Life coloniallife.com provides workplace insurance benefits including disability, life, accident, dental, and critical illness coverage to support workers and families	Insurance	🇺🇸 Columbia	8,479	1939
9	BlueCross BlueShield of South Carolina southcarolinablues.com Largest insurance company in South Carolina, leading government contract administrator, operates sophisticated data processing centers, offers health plans and employee benefits.	Insurance	🇺🇸 Columbia	6,503	1946
10	Merkle merkle.com A leading CXM company specializing in delivering personalized customer experiences through data, technology, analytics, and marketing strategies for Fortune 1000 companies	Business Consulting and Services	🇺🇸 Columbia	5,624	n/a
11	Shelter Insurance Companies shelterinsurance.com Property and casualty insurance provider offering auto, home, life, renters, farm, business, and specialty insurance products across multiple states.	Insurance	🇺🇸 Columbia	4,253	1946
12	W. R. Grace grace.com Supplies catalysts, engineered materials, process technologies, fine chemicals. Industries enhance modern life. Manufactures renewable fuels, pharmaceuticals, food packaging better, faster, smarter.	Chemical Manufacturing	🇺🇸 Columbia	4,244	n/a
13	EquipmentShare equipmentshare.com A nationwide equipment and digital solutions company empowering construction industry with technology platform, equipment rental, retail, and service solutions	Construction	🇺🇸 Columbia	4,193	2014
14	GP Strategies Corporation gpstrategies.com Provides consulting, learning services, and technology solutions to help organizations improve workforce performance and achieve business transformation through people.	Business Consulting and Services	🇺🇸 Columbia	4,090	1966
15	Richland School District 2 richland2.org The company focuses on learning, character development, community partnerships, and celebrating achievements to create a joyful and innovative environment for students	Education Administration Programs	🇺🇸 Columbia	4,058	1921
16	Maxim Healthcare Services maximhealthcare.com Providing comprehensive healthcare services including skilled nursing, rehabilitation, companion care, and behavioral care for individuals with chronic illnesses and disabilities	Hospitals and Health Care	🇺🇸 Columbia	3,694	1988
17	Veterans United Home Loans veteransunited.com Providing personalized VA home loan services and abundant information to veterans, military members, and their families across the U.S.	Financial Services	🇺🇸 Columbia	3,372	2002
18	Palmetto Health palmettohealth.org A leading healthcare system in the South Carolina Midlands region, providing compassionate care through six hospitals, a medical group, and training programs	Hospitals and Health Care	🇺🇸 Columbia	3,200	1998
19	University of Missouri Health Care muhealth.org A premier academic medical center in Missouri offering a full spectrum of care, from primary to specialized treatment for severe illnesses and injuries	Hospitals and Health Care	🇺🇸 Columbia	2,962	1839
20	MICROS Systems Inc oracle.com A former provider of hospitality technology solutions acquired by Oracle, now part of Oracle Hospitality Visit Oracle's LinkedIn page for updates	Software Development	🇺🇸 Columbia	2,493	1977
21	The Cleaning Authority thecleaningauthority.com A valuable home cleaning franchise opportunity for forward-thinking entrepreneurs to invest in themselves and build a rewarding business for the future	Consumer Services	🇺🇸 Columbia	2,492	1977
22	South Carolina Department of Social Services careers.sc.gov This company in South Carolina focuses on promoting safety, stability, and well-being of children, vulnerable adults, and families to achieve permanency and strength	Government Administration	🇺🇸 Columbia	2,463	n/a
23	Tenable tenable.com Exposes and closes cybersecurity gaps, unifies security visibility, insight, and action across the attack surface for organizations globally.	Computer and Network Security	🇺🇸 Columbia	2,361	n/a
24	Nelson Mullins Riley & Scarborough nelsonmullins.com Established in 1897, this firm with over 1,000 attorneys and professionals provides legal services across 33 offices in 17 states	Law Practice	🇺🇸 Columbia	2,142	1897
25	Columbia College ccis.edu A college located in Columbia, MO, inviting visitors to explore their main campus in mid-Missouri Emphasizing the hashtag #WeAreCC	Higher Education	🇺🇸 Columbia	1,878	1851
26	Jensen Hughes jensenhughes.com A global leader in fire protection engineering and risk management, offering expertise in safety and security consulting, emergency management, and digital innovation	Professional Services	🇺🇸 Columbia	1,851	n/a
27	South Carolina Department of Transportation scdot.org A government agency in South Carolina developing and maintaining transportation systems, offering careers in engineering, IT, finance, HR, communications	Civil Engineering	🇺🇸 Columbia	1,848	n/a
28	Advarra advarra.com Advarra enhances clinical research by providing IRB and IBC review solutions, innovative technologies, and industry connections to optimize trial participant safety and research performance	Research Services	🇺🇸 Columbia	1,839	1983
29	Howard Community College howardcc.edu Public community college in Howard County, Maryland, offering associate degrees, certificates, workforce training, and continuing education classes to 30,000 students annually	Higher Education	🇺🇸 Columbia	1,785	1970
30	Pure Fishing purefishing.com Global supplier of fishing tackle, lures, rods, and reels with multiple renowned brands, focused on innovation, sustainability, and customer satisfaction.	Sporting Goods Manufacturing	🇺🇸 Columbia	1,706	n/a
31	South Carolina Department of Social Services sc.gov A public agency in South Carolina providing services to investigate abuse, distribute food assistance, collect child support, and staff emergency shelters Mission is to promote safety and well-being Vision includes creating jobs, ensuring children have stable families	Government Administration	🇺🇸 Columbia	1,668	1937
32	Southern Tire Mart stmtires.com A leading truck retreader and commercial tire dealer in North America, providing high-quality tires and services while prioritizing employee satisfaction and growth opportunities	Motor Vehicle Manufacturing	🇺🇸 Columbia	1,660	1973
33	Columbia Public Schools cpsk12.org A district accredited with distinction in Missouri, providing excellent education from preschool to adult career education with a focus on excellence	Education Administration Programs	🇺🇸 Columbia	1,642	n/a
34	Palmetto GBA palmettogba.com Providing Medicare claims processing, customer service, and benefits administration support to government and commercial healthcare customers nationwide.	IT Services and IT Consulting	🇺🇸 Columbia	1,488	1965
35	ViPS clearavenue.com clearAvenue is a company that specializes in providing innovative technology solutions and services to help businesses streamline their operations and achieve success	IT Services and IT Consulting	🇺🇸 Columbia	1,461	1980
36	MBS mbsbooks.com The company specializes in providing cutting-edge retail technology, forming strong partnerships, and offering expertise in the college store industry	Education	🇺🇸 Columbia	1,450	1973
37	South Carolina Department of Corrections governmentjobs.com A state agency in South Carolina dedicated to protecting the public, providing rehabilitation for inmates, and promoting professional excellence and fiscal responsibility	Law Enforcement	🇺🇸 Columbia	1,440	n/a
38	Midlands Technical College midlandstech.edu A forward-thinking technical college offering diverse programs, hands-on training, and high-tech facilities for students to pursue careers or transfer to four-year institutions	Higher Education	🇺🇸 Columbia	1,371	1974
39	Boone Health boone.health A leading regional hospital center providing quality healthcare in cardiovascular medicine, obstetrics, neurology, oncology, orthopedics, and surgical services with excellent patient service	Hospitals and Health Care	🇺🇸 Columbia	1,300	n/a
40	Connections Academy connectionsacademy.com Provider of tuition-free, accredited K-12 public education with quality curriculum and state-certified teachers for families seeking flexible structured alternative	E-Learning Providers	🇺🇸 Columbia	1,287	2001
41	Maury Regional Health mauryregional.com Not-for-profit health system providing hospitals, clinics, surgery centers, outpatient services, and physician practices across southern Middle Tennessee.	Hospitals and Health Care	🇺🇸 Columbia	1,236	1953
42	Hubbell Power Systems hubbell.com Designs and manufactures transmission, distribution, and substation products for utilities, civil construction, transportation, gas, and water industries worldwide	Appliances, Electrical, and Electronics Manufacturing	🇺🇸 Columbia	1,215	1994
43	Farm Bureau Insurance of Tennessee fbitn.com Leading Tennessee insurance provider offering auto, home, and life insurance with the largest coverage in the state, backed by local agents and regional claims centers	Insurance	🇺🇸 Columbia	1,164	1948
44	Johns Hopkins Howard County Medical Center hopkinsmedicine.org Providing award-winning health care services to improve community health through innovation, collaboration, service excellence, diversity, and patient safety since 1973	Hospitals and Health Care	🇺🇸 Columbia	1,162	n/a
45	Club Car Wash clubcarwash.com A car wash company founded in 2006, with locations across the Midwest offering employment opportunities through their careers site	Motor Vehicle Manufacturing	🇺🇸 Columbia	1,161	2006
46	Lower lower.com A direct-to-consumer lender focused on making homeownership more accessible, offering a best-in-class customer experience with billions in home loans funded	Financial Services	🇺🇸 Columbia	1,069	2018
47	South Carolina Army National Guard nationalguard.com Explore opportunities to serve the South Carolina Army National Guard part-time and receive education assistance, paid job training, and benefits Connect now!	Armed Forces	🇺🇸 Columbia	1,015	1670
48	Richland County Government richlandcountysc.gov Local government entity in central South Carolina, serving Richland County residents by providing accessible services and promoting community well-being and economic growth	Government Administration	🇺🇸 Columbia	979	1785
49	Huntress huntress.com Provides a fully managed security platform, combining endpoint detection, identity protection, SIEM, and security training for mid-market businesses and MSPs.	Computer and Network Security	🇺🇸 Columbia	939	2015
50	SOUTH CAROLINA DEPARTMENT OF MENTAL HEALTH scdmh.org public mental health system providing outpatient and inpatient clinical services to approximately 100,000 patients annually across South Carolina	Mental Health Care	🇺🇸 Columbia	871	1821
51	AgFirst Farm Credit Bank agfirst.com Wholesale funding, technology, and support services to local agricultural and rural lenders across 15 states and Puerto Rico.	Banking	🇺🇸 Columbia	848	1916
52	STRUCTURAL structural.net Leader in specialty contracting services, integrating technology solutions to improve, protect, and repair infrastructure for commercial, public, industrial, and power markets	Construction	🇺🇸 Columbia	846	n/a
53	Howard County General Hospital hopkinsmedicine.org Providing award-winning healthcare services since 1973, committed to improving community health through innovation, collaboration, diversity, service excellence, and patient safety	Hospitals and Health Care	🇺🇸 Columbia	843	1973
54	Blend blend360.com A premier AI services provider combining data science, technology, and human expertise to co-create impactful solutions for clients Unlocking value through innovation	Professional Services	🇺🇸 Columbia	823	2016
55	Tate tateglobal.com The company specializes in access floor and underfloor service distribution solutions for high-performance, sustainable commercial and data center environments, optimizing energy efficiency and infrastructure flexibility	Construction	🇺🇸 Columbia	817	1963
56	Infojini Inc infojiniconsulting.com Delivers innovative IT services and solutions, empowering startups and enterprises through software engineering, cloud, data, and cybersecurity expertise.	IT Services and IT Consulting	🇺🇸 Columbia	786	2006
57	Voyatek voyatek.com Provides tailored technology solutions for public sector agencies and higher education, focusing on tax, health, justice, and safety improvements.	IT Services and IT Consulting	🇺🇸 Columbia	775	2005
58	Lower lower.company We make homeownership more accessible by offering mortgage lending services through a variety of brands and branches across the country	Financial Services	🇺🇸 Columbia	747	2014
59	Your Health yourhealth.org Providing health services in the comfort of your own home, at physicians' offices, and through telehealth to help you feel better	Hospitals and Health Care	🇺🇸 Columbia	741	n/a
60	Shimadzu Scientific Instruments ssi.shimadzu.com A leader in scientific instrument development, offering analytical solutions, training, collaboration centers, and products to laboratories and research institutions worldwide	Biotechnology Research	🇺🇸 Columbia	741	1975
61	Lindsey Wilson University lindsey.edu A liberal arts college founded in 1903, dedicated to cultivating student growth through values-centered education and daily learning experiences	Higher Education	🇺🇸 Columbia	733	1903
62	Benedict College benedict.edu A private liberal arts institution focused on providing high quality education, research, and public service opportunities to empower students for societal good	Education Administration Programs	🇺🇸 Columbia	706	1870
63	MFA Incorporated mfa-inc.com Midwest-based regional farm supply and marketing cooperative serving over 45,000 farmer/owners in Missouri and adjacent states, providing products and services to help farmers succeed	Farming	🇺🇸 Columbia	701	1914
64	McAngus Goudelock & Courie mgclaw.com A metrics-driven law firm specializing in serving the insurance industry, insureds, and self-insureds Known for their focus on results	Law Practice	🇺🇸 Columbia	691	1995
65	STRUCTURAL TECHNOLOGIES structuraltechnologies.com Specializing in infrastructure solutions, the company offers state-of-the-art products and engineered solutions for repair, maintenance, and construction projects across various industries	Construction	🇺🇸 Columbia	683	1976
66	South Carolina Department of Employment and Workforce dew.sc.gov The company is responsible for paying unemployment benefits, collecting taxes, connecting job seekers with employers, and providing employment services	Government Relations Services	🇺🇸 Columbia	671	n/a
67	SC Department of Health and Human Services scdhhs.gov Administers Medicaid program providing healthcare to low-income, elderly, and disabled residents while ensuring confidentiality and security of health information.	Government Administration	🇺🇸 Columbia	670	n/a
68	MEM mem-ins.com Missouri Employers Mutual is dedicated to providing top work comp insurance, personalized claims management, and workplace safety expertise to Missouri employers	Insurance	🇺🇸 Columbia	669	1995
69	Columbia Association columbiaassociation.org A non-profit service corporation managing a master planned community in Columbia, MD, providing recreational, cultural, and community services while enhancing overall quality of life	Wellness and Fitness Services	🇺🇸 Columbia	666	1966
70	Planned Systems International plan-sys.com Providing government customers with innovative IT solutions including cybersecurity, cloud migration, systems engineering, augmented reality, and DevSecOps to enhance security and efficiency.	IT Services and IT Consulting	🇺🇸 Columbia	650	1988
71	Columbia International University ciu.edu An educational institution offering career-focused programs and degrees with a biblical worldview to prepare students for success in the workplace and ministry	Higher Education	🇺🇸 Columbia	647	1923
72	UCI Medical Affiliates ucimedinc.com Provides management services for various medical centers in South Carolina, offering urgent care, specialty practices, and physical therapy to patients	Executive Offices	🇺🇸 Columbia	633	1981
73	Barnes and Noble Book Store A global retailer offering affordable books, movies, music, toys, games, gifts, and more, with free shipping on orders over $25	Technology, Information and Internet	🇺🇸 Columbia	629	n/a
74	Maury County Public Schools mauryk12.org A school district in Southern Middle Tennessee with 23 campuses, serving 13,000 students from pre-K through 12th grade, focused on lifelong learning and success	Education Administration Programs	🇺🇸 Columbia	628	n/a
75	The Greene Turtle Sports Bar & Grille thegreeneturtle.com Established in 1976, this company is a community hangout offering great food and drinks in a casual atmosphere centered around sports and unity	Food and Beverage Services	🇺🇸 Columbia	619	1976
76	Emery Sapp & Sons, Inc.emerysapp.com A 100% employee-owned contractor specializing in heavy civil projects, offering innovative infrastructure solutions, excavation, grading, utilities, bridge construction, and paving services	Construction	🇺🇸 Columbia	592	1972
77	VC3 vc3.com Managed IT and cybersecurity services provider serving municipalities, financial organizations, and businesses in North America Specializing in bridging technology gaps and managing cyber risks	IT Services and IT Consulting	🇺🇸 Columbia	590	n/a
78	Columbia State Community College columbiastate.edu A two-year college in southern Middle Tennessee committed to increasing access and diversity, with multiple campuses and a focus on community education	Higher Education	🇺🇸 Columbia	589	1966
79	Culligan Water Conditioning culliganmidmissouri.com Specializes solely in water and its purity stages, providing residential, commercial, and industrial water treatment solutions, including bottled water delivery and specialized pure water systems.	Consumer Services	🇺🇸 Columbia	580	1970
80	MFA Oil Company mfaoil.com A farmer-owned cooperative supplying fuels, lubricants & propane in multiple states, also operating convenience stores and tire franchises Visit website for more	Oil and Gas	🇺🇸 Columbia	572	1929
81	South Carolina Department of Juvenile Justice djj.sc.gov A state agency in South Carolina committed to serving youth offenders by providing custodial care, rehabilitation, education, and workforce development opportunities	Public Safety	🇺🇸 Columbia	570	n/a
82	Medico Healthcare Services & Technologies medicoinc.com Healthcare services and technology company specializing in medical billing, consulting, practice analytics, and revenue cycle management solutions for healthcare practices	Hospitals and Health Care	🇺🇸 Columbia	566	1995
83	LB&B Associates Inc lbbassociates.com Provider of facilities management, logistics, and training solutions for government and commercial clients Focus on expertise, communication, customer knowledge, and employee empowerment	Facilities Services	🇺🇸 Columbia	562	1992
84	Missouri State Public Defender publicdefender.mo.gov A state agency in Missouri providing legal representation to indigent citizens accused of crimes, with divisions offering direct representation and support	Legal Services	🇺🇸 Columbia	561	n/a
85	Flat Branch Home Loans flatbranchhomeloans.com A company offering low rate mortgages in 30 states with exceptional service, expert staff, and assistance for home purchases or refinancing	Financial Services	🇺🇸 Columbia	535	2005
86	First Citizens Bank and Trust Company, Inc.firstcitizens.com Financial institution offering personal, business, commercial, and wealth services nationwide, with a focus on strength, stability, innovation, and long-term thinking	Financial Services	🇺🇸 Columbia	527	1898
87	City of Columbia, Missouri como.gov The company focuses on creating an environment where all individuals can thrive in their daily lives, work, education, and recreational activities	Government Administration	🇺🇸 Columbia	522	n/a
88	Darla Moore School of Business at the University of South Carolina sc.edu University of South Carolina's Darla Moore School of Business provides official information and updates for students, faculty, and followers	Higher Education	🇺🇸 Columbia	512	1919
89	South Carolina Department of Natural Resources dnr.sc.gov Advocating for and stewarding natural resources in South Carolina to enhance quality of life through understanding, sustainable use, and safe enjoyment	Government Administration	🇺🇸 Columbia	510	1905
90	South Carolina Department of Revenue dor.sc.gov This organization collects 95% of South Carolina's General Fund, striving to provide easy compliance and be a trusted partner for taxpayers and businesses	Government Administration	🇺🇸 Columbia	507	n/a
91	Clarity clarityinnovates.com A technology company focused on developing force-enhancing software for government, promoting DevSecOps, Agile methodologies, and fostering a culture of creativity and growth	Software Development	🇺🇸 Columbia	505	2011
92	AbsoluteCare absolutecare.com Specializing in HIV/AIDS treatment, <Organization> has evolved to offer comprehensive primary care services for underserved individuals with various health conditions	Hospitals and Health Care	🇺🇸 Columbia	501	2000
93	LexiCode lexicode.com Industry-leading Health Information Management services with a team of over 1,700 credentialed professionals offering medical coding, auditing, education, and consulting solutions	Hospitals and Health Care	🇺🇸 Columbia	499	1981
94	Palmetto State Armory palmettostatearmory.com A passionate team founded a business offering firearms, tactical gear, and outdoor products with a focus on quality and customer service	Retail	🇺🇸 Columbia	492	2008
95	Verbal Beginnings verbalbeginnings.com Family-focused professionals providing comprehensive autism services in MD, PA, DE, DC, and NoVA region Tailored treatment programs for communication, behavior, social skills, and more	Individual and Family Services	🇺🇸 Columbia	482	2011
96	University of South Carolina School of Medicine sc.edu Established in 1974, USC SOM improves South Carolinians' health by training physicians, genetic counselors, nurse anesthetists, and biomedical scientists in a nurturing environment	Higher Education	🇺🇸 Columbia	477	1977
97	Baywood Hotels \| Hotel Management & Development baywoodhotels.com A leading hospitality industry leader with a diverse portfolio of top brands, emphasizing employee development and growth opportunities	Hospitality	🇺🇸 Columbia	473	1975
98	Technetics Group technetics.com Design and manufacture custom-engineered seals, components, and sub-systems for extreme applications in semiconductor, aerospace, nuclear, and life sciences industries.	Industrial Machinery Manufacturing	🇺🇸 Columbia	467	n/a
99	FEI Systems feisystems.com A leading IT organization specializing in healthcare solutions for federal, state, and local governments, with expertise in behavioral health data systems and software development	IT Services and IT Consulting	🇺🇸 Columbia	455	1999
100	Intersoft Data Labs intsof.com Providing innovative software development, product engineering, and infrastructure services across multiple industries with a focus on quality and accelerated delivery.	IT Services and IT Consulting	🇺🇸 Columbia	451	2003

Turn this list into pipeline

Tamtam finds the decision-makers at every company on a list like this one, with verified emails, phone numbers and the buying signals that tell you when to reach out.

Build your own list, free

How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Oct 24, 2026.

More company lists in Columbia

IT Services and IT Consulting companies in Columbia 32

The same list elsewhere in United States

The largest companies in the United States 91,669
The largest companies in California 12,813
The largest companies in New York State 10,485
The largest companies in Texas 8,086
The largest companies in Florida 4,945
The largest companies in Illinois 4,175
The largest companies in Pennsylvania 3,110
The largest companies in Massachusetts 3,093
The largest companies in Georgia 2,632
The largest companies in Ohio 2,618
The largest companies in New Jersey 2,569
The largest companies in Virginia 2,503
The largest companies in Michigan 2,346
The largest companies in North Carolina 2,174
The largest companies in Alabama 1,806
The largest companies in Washington State 1,785
The largest companies in Colorado 1,774
The largest companies in Minnesota 1,700
The largest companies in Maryland 1,527
The largest companies in Wisconsin 1,482
The largest companies in New York 6,920
The largest companies in San Francisco 2,030
The largest companies in Houston 1,791
The largest companies in Chicago 1,668