| # | Company | Employees |
|---|---|---|
| 1 |
Principal Financial Groupprincipal.com
Provides retirement planning, investment management, and insurance products globally to help individuals and businesses build long-term wealth and achieve overall financial security. |
24,405 |
| 2 |
Wells Fargo Home Mortgagewellsfargo.com
A retail mortgage lender providing construction, renovation, home buying, refinancing, jumbo, adjustable-rate, and reverse mortgages to homeowners and homebuyers |
13,964 |
| 3 |
MercyOnemercyone.org
Integrated system of hospitals and clinics providing accessible care, training caregivers, and improving community well-being with a dedication to compassion, transformation, and trust |
7,091 |
| 4 |
Des Moines Public Schoolsdmschools.org
Public school district offering comprehensive curriculum, supporting diverse students, preparing them for college, careers, and global citizenship. |
3,663 |
| 5 |
BHlivebh.com
Multifamily property management and ownership with a focus on innovation, team investment, and ethical business practices nationwide. |
3,341 |
| 6 |
Meredith Corporationpeople.inc
A leading media company producing trusted content across digital, print, and TV platforms, engaging 95% of American women with iconic brands |
3,258 |
| 7 |
LCSlcsnet.com
Leading provider of senior lifestyle products/services, specializing in Life Plan Communities, independent living, assisted living, memory care, real estate, insurance, and in-home care nationwide |
2,561 |
| 8 |
F&Gfglife.com
Established in 1959, headquartered in Des Moines, Iowa, providing unique life insurance and annuity solutions nationwide with a focus on financial security |
2,406 |
| 9 |
Ruan Transportation Management Systemsruan.com
Family-owned transportation provider offering Dedicated Contract Transportation, Managed Transportation, Warehousing, and Brokerage Support Services with over 90 years of experience Operating nationwide |
2,339 |
| 10 |
Principal Asset Managementprincipalam.com
Providing customized investment solutions through a multi-boutique platform to help individuals and institutions achieve their financial goals. |
2,317 |
| 11 |
Primary Health Care, Inc (PHC)phciowa.org
Provider of comprehensive healthcare and supportive services for vulnerable populations in central Iowa, offering medical, dental, behavioral health, pharmacy, HIV care, and homeless support |
2,299 |
| 12 |
MidAmerican Energy Companymidamericanenergy.com
Energy company serving over 15 million customers in Iowa, Illinois, Nebraska, and South Dakota, providing timely and relevant information on energy-related topics |
2,295 |
| 13 |
TMC Transportationtmctrans.com
A leading employee-owned flatbed carrier and logistics provider offering efficient transportation solutions for a variety of freight nationwide |
2,226 |
| 14 |
Kemin Industrieskemin.com
Global manufacturer providing over 500 specialty ingredients for diverse industries including human health, animal feed, pet food, and crop technologies, improving quality of life. |
2,221 |
| 15 |
Wellmark Blue Cross and Blue Shieldwellmark.com
This company provides health coverage to over 2 million members in Iowa and South Dakota, part of a national network insuring over 100 million people |
2,195 |
| 16 |
EMC Insurance Companiesemcinsurance.com
Provides property and casualty insurance products and services across the United States with a focus on workersโ compensation protection. |
2,149 |
| 17 |
Drake Universitylinktr.ee
Private university in Des Moines, Iowa offering undergraduate and graduate programs in various fields with a focus on intimate class sizes and successful career outcomes |
1,882 |
| 18 |
CDS Globalcds-global.com
Subscription management and order fulfillment services for media, nonprofits, education, utilities, and consumer products with data-driven customer engagement. |
1,357 |
| 19 |
Highline Collegehighline.edu
A leading community college in South King County offering diverse programs, degrees, and certificates, with a commitment to diversity and social justice |
1,242 |
| 20 |
The Weitz Companyweitz.com
Full-service construction company specializing in design-build, general contracting, and construction management across industrial and commercial sectors nationwide. |
1,241 |
| 21 |
MEP Jobsmepjobs.com
MEP Jobs is a specialized online job board for professionals in mechanical, electrical, and plumbing industries, connecting candidates with industry-specific employers |
1,022 |
| 22 |
American Equityamerican-equity.com
Provides annuity products through independent agents to help individuals achieve dignified, peaceful retirements with reliable financial growth and community commitment. |
989 |
| 23 |
EFCO Forming & Shoring Solutionsefcoforms.com
EFCO provides safe, reliable, and cost-efficient concrete formwork solutions for construction projects, focusing on efficiency, quality, and customer service |
930 |
| 24 |
The Waldinger Corporationwaldinger.com
Mechanical, electrical, and sheet metal contracting services with a people-first approach, operating across the Midwest United States. |
927 |
| 25 |
City of Des Moinesdsm.city
The company provides city services, infrastructure, and community involvement to enhance the quality of life for residents and visitors in Des Moines, Iowa |
898 |
| 26 |
Mitteramittera.com
The company offers integrated solutions in print, mail, and marketing services to help businesses achieve growth, brand awareness, and marketing goals |
863 |
| 27 |
Iowa Department of Health and Human Serviceshhs.iowa.gov
State government agency in Iowa providing quality programs and services to enhance health and resilience of individuals, families, and communities |
850 |
| 28 |
Broadlawns Medical Centerbroadlawns.org
A leading medical center with over 100 physicians and 1,200 employees, providing high-quality healthcare through various services and training programs |
838 |
| 29 |
Mercy Medical Center - Des Moinesmercyone.org
A not-for-profit Catholic health care provider in Des Moines operating multiple hospitals, employing 7,000 staff members and serving as a major referral center |
817 |
| 30 |
Life Care ServiceslifecareservicesLCS.com
The company is a nationwide leader in managing full-service senior living communities, offering operations, marketing, and sales management for various types of communities |
765 |
| 31 |
Iowa Judicial Branchiowacourts.gov
Interpreting and applying Iowa laws, ensuring equal justice, providing dispute resolution through supreme court, court of appeals, and district courts Employing 1,800+ officers |
709 |
| 32 |
OpenLoopopenloophealth.com
A health tech leader providing white-labeled clinical support for companies expanding virtual care services nationwide, aiming to bring healing anywhere |
709 |
| 33 |
Bankers Trustbankerstrust.com
A leading financial institution offering commercial and consumer banking services, innovative financial solutions, community support, and numerous awards for excellence |
684 |
| 34 |
Grand View Universitygrandview.edu
A private liberal arts university in Des Moines offering bachelor's and master's degrees, focusing on career-oriented, diverse education |
632 |
| 35 |
Iowa Workforce Developmentworkforce.iowa.gov
Iowa Workforce Development provides employment services, education, and regulates health and safety laws to enhance the income, productivity, and safety of Iowans |
622 |
| 36 |
Iowa Department of Correctionsdoc.iowa.gov
This company manages and oversees the corrections system in Iowa, including prisons, probation, and parole services |
573 |
| 37 |
Lutheran Services in Iowalsiowa.org
A leading social service agency in Iowa, fostering positive change in communities through partnerships with local leaders for impactful results |
514 |
| 38 |
Berkshire Hathaway Energybrkenergy.com
A sustainable energy company with a $1338 billion portfolio serving 12 million customers with low-cost, safe, and reliable service Headquarters in Iowa |
480 |
| 39 |
Office of the Attorney General of Iowaiowaattorneygeneral.gov
The Office of the Attorney General in Iowa provides legal advice, representation, and protection for the state government and its residents |
465 |
| 40 |
Federal Home Loan Bank of Des Moinesfhlbdm.com
Member-owned cooperative of community banks, credit unions, and financial institutions in 13 states, focused on advancing economic development and affordable housing initiatives |
442 |
| 41 |
Wellabewellabe.com
A group of insurance companies based in Des Moines, IA, offering a variety of insurance products like Medicare supplement, dental, and critical illness coverage |
425 |
| 42 |
TWC Services, Inc.twcservices.com
This company offers HVAC, refrigeration, commercial cooking equipment, and beverage maintenance services in the southeast United States since 1906 |
419 |
| 43 |
Iowa Department of Natural Resourcesiowadnr.gov
This company manages fish/wildlife programs, preserves forests/prairies, offers recreation in state parks, enforces environmental laws, and promotes natural resource stewardship |
416 |
| 44 |
Dee Zee, Incdeezee.com
Manufacturer of durable, functional, and stylish truck accessories since 1977 Committed to eco-friendly practices and made in America with OEM partnerships |
413 |
| 45 |
Iowa Air National Guardairforce.com
The Iowa Air National Guard is the aerial militia of Iowa, part of the Iowa National Guard and under state jurisdiction unless federalized |
405 |
| 46 |
RE/MAX Conceptsconcepts-des-moines-ia.remax.com
Real estate company with 10 office locations in Iowa offering a range of services, including buying, selling, new construction, commercial, luxury properties, and relocation |
377 |
| 47 |
Iowa Department of Educationeducate.iowa.gov
Provides support and oversight for Iowa's education system, including public and nonpublic schools, area education agencies, community colleges, and teacher preparation programs |
368 |
| 48 |
Lightedgelightedge.com
LightEdge provides technology solutions to bring the benefits of public cloud to enterprise IT workloads, reducing complexity and prioritizing security, performance, and client needs |
359 |
| 49 | 313 | |
| 50 |
PDMpdmprecast.com
Employee-owned producer of precast concrete and structural steel fabricator Specializing in architectural and structural components for various construction projects |
311 |
| 51 |
American Republic Insurance Servicesarisagency.com
Providing retirement market with advice, services, and tailored insurance products through highly-skilled representatives with top-rated insurance companies since 1929 |
281 |
| 52 |
Intoxalockintoxalock.com
A company based in Des Moines, Iowa, specializing in alcohol monitoring devices and ignition interlock technology, utilizing cutting-edge fuel cell technology |
273 |
| 53 |
Windstream
Provider of Unified Communications as a Service (UCaaS) solutions for businesses to streamline communication channels and enhance collaboration among teams |
263 |
| 54 |
BHE Renewablesbherenewables.com
A renewable energy company with a large US portfolio focusing on generation from wind, water, solar, and geothermal sources Headquartered in Des Moines, Iowa |
255 |
| 55 |
Willis Automotivewillisauto.com
Offering a wide selection of quality vehicles and professional service to meet all automotive needs with a commitment to customer satisfaction |
227 |
| 56 |
Katecho, LLCkatecho.com
Internationally recognized OEM specializing in medical and cosmetic devices, offering engineering, manufacturing, regulatory support, and logistics services with a focus on innovation and quality |
210 |
| 57 |
The Des Moines Registerdesmoinesregister.com
The company is a longstanding source of news and information in Iowa, providing print and digital content, while supporting communities and businesses |
205 |
| 58 |
Graham Construction a 3G Company3gcos.com
A leading Construction Manager and General Contractor in the Midwest, specializing in healthcare, complex projects, renovations, and maintaining long-term relationships |
202 |
| 59 |
Global Farmer Networkglobalfarmernetwork.org
Non-profit advocating for free trade and farmers' freedom to choose tools for sustainable productivity Giving farmers a voice in global food security dialogue |
199 |
| 60 |
Doll Distributingdolldistributing.com
A beverage distribution company originally founded in 1965, serving approximately 2,500 customers in Southwest and Central Iowa with locations in multiple cities |
186 |
| 61 |
Channel Prime Alliancechannelpa.com
A distributor of plastic, rubber, and elastomer products in North America with a focus on quality, customer satisfaction, and a diverse supplier product offering |
182 |
| 62 |
Excell Brandsexcellbrands.com
A leading Category Manager for Trading Cards & Trend Collectibles in North America, offering comprehensive Category Management for thousands of store fronts |
180 |
| 63 |
Kemin Pet Food & Renderingkemin.com
Specializing in pet food and rendering technologies, this company provides safe ingredients to enhance pets' health and quality of life globally |
177 |
| 64 |
Nyemaster Goode, P.C.nyemaster.com
Established in 1918, this Iowa-based law firm with offices in Des Moines, Ames, and Cedar Rapids provides comprehensive legal solutions to companies and individuals |
177 |
| 65 |
JT Logisticsjtlogistics.com
A global logistics provider offering transportation, storage, and supply chain solutions to leading brands worldwide Contact us for unmatched services |
168 |
| 66 |
IOWA METHODIST MEDICAL CENTERunitypoint.org
A network of 4 top hospitals in Des Moines united to deliver high-quality healthcare services and personalized patient care |
166 |
| 67 |
Iowa Vocational Rehabilitation Servicesworkforce.iowa.gov
Company dedicated to helping individuals with disabilities find integrated community employment and assisting high school students transition to work |
162 |
| 68 |
Eurofins US Food, Feed, & Supplement Testingeurofinsus.com
Commercial testing laboratories offering comprehensive food safety testing services, specializing in a range of laboratory testing methods for various industries in the United States |
160 |
| 69 |
EveryStepeverystep.org
An Iowa-based nonprofit providing healthcare and community services since 1908, offering a diverse range of programs to support individuals, families, and communities through difficult times |
160 |
| 70 |
Two Rivers Marketingtworiversmarketing.com
A leading full-service B2B agency in Des Moines, Iowa, specializing in marketing complex products for industrial, construction, transportation, energy, financial, and agricultural sectors |
153 |
| 71 |
Iowa Department of Managementdom.iowa.gov
The company oversees and manages information technology resources for state government, providing leadership, direction, coordination, and accountability |
150 |
| 72 |
Solar Transportsolartransport.com
Specializing in tank truck transportation, Solar Transport efficiently delivers refined petroleum products, prioritizing safety and timeliness for over 50 years |
148 |
| 73 |
Corporate Imagecorp-image.com
A leading US packaging manufacturer specializing in innovative presentation materials and luxury packaging solutions with a focus on sustainability and quality |
92 |
| 74 |
Grakongrakon.com
Specializing in advanced lighting systems for premier OEM vehicle manufacturers, Grakon delivers innovative designs for interior and exterior lighting solutions globally |
81 |
| 75 |
Star Equipment, Ltd.starequip.com
A family-owned company providing top-quality construction equipment, training, and services to maximize profitability while minimizing downtime for clients |
63 |
| 76 |
GlobalVetLinkglobalvetlink.com
GlobalVetLink pioneers digital animal health compliance solutions, offering online platforms for efficient management of animal health certificates, EIA testing, and prescriptions |
53 |
| 77 |
Mariotti USAmariottiusa.com
A leading lift truck manufacturer with over 15 years in North America, known for innovative solutions, superior customer service, and a comprehensive dealer network |
29 |
| 78 |
Next Level Venturesnextlevelvc.com
A venture capital firm investing in innovative companies, specializing in fintech and Iowa markets, offering financial and operational support to help companies scale |
22 |
| 79 |
BLK & Bold Specialty Beveragesblkandbold.com
Specialty beverage company offering premium coffees and teas that support urban youth initiatives and address industry voids with quality, convenience, community, and diversity |
13 |
| 80 |
Nichols Equipmentnichols-equipment.com
Des Moines-based company offering sales, rental, and service of construction equipment and aftermarket undercarriage parts, with a focus on customer satisfaction |
8 |
| 81 |
InfraLytiksinfralytiks.com
This company specializes in complex data analytics and automation, providing reliable insights to help businesses make faster and more informed decisions |
5 |
Turn this list into pipeline
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How this list is built
Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Oct 24, 2026.
The same list elsewhere in United States
- The largest companies in the United States 91,669
- The largest companies in California 12,813
- The largest companies in New York State 10,485
- The largest companies in Texas 8,086
- The largest companies in Florida 4,945
- The largest companies in Illinois 4,175
- The largest companies in Pennsylvania 3,110
- The largest companies in Massachusetts 3,093
- The largest companies in Georgia 2,632
- The largest companies in Ohio 2,618
- The largest companies in New Jersey 2,569
- The largest companies in Virginia 2,503
- The largest companies in Michigan 2,346
- The largest companies in North Carolina 2,174
- The largest companies in Alabama 1,806
- The largest companies in Washington State 1,785
- The largest companies in Colorado 1,774
- The largest companies in Minnesota 1,700
- The largest companies in Maryland 1,527
- The largest companies in Wisconsin 1,482
- The largest companies in New York 6,920
- The largest companies in San Francisco 2,030
- The largest companies in Houston 1,791
- The largest companies in Chicago 1,668