The 54 largest companies in Fort Myers (2026 list)

#	Company	Industry	Headquarters	Employees	Founded
1	Lee Health jobs.leehealth.org Healthcare provider in Southwest Florida with 4 acute care hospitals, 2 specialty hospitals, and over 13,000 employees, committed to inspiring health and diversity	Hospitals and Health Care	🇺🇸 Fort Myers	8,914	1916
2	School District of Lee County leeschools.net One of the largest school districts in the nation, educating 93,000 students in grades K-12 and offering opportunities for adult learners	Education Administration Programs	🇺🇸 Fort Myers	6,410	n/a
3	Chico's FAS, Inc.chicos.com A fashion company offering carefully curated collections with quality, comfort, and versatility, inspiring women to express their personality with confidence through unique pieces and styling options	Retail	🇺🇸 Fort Myers	5,588	1983
4	Florida Gulf Coast University fgcu.edu Academic institution offering over 95 undergraduate and graduate programs with a focus on sustainability, service learning, and meeting regional workforce demands	Higher Education	🇺🇸 Fort Myers	4,482	1991
5	White House Black Market whitehouseblackmarket.com This fashion brand embraces the complexity of modern women with feminine, strong, and approachable looks, inspired by the iconic contrast of White + Black	Retail	🇺🇸 Fort Myers	2,922	1985
6	Florida Cancer Specialists & Research Institute flcancer.com A leading independent oncology/hematology practice providing world-class cancer care in community-based settings across Florida with a focus on innovative treatments and research	Hospitals and Health Care	🇺🇸 Fort Myers	2,895	1984
7	Lee County leegov.com Local government providing public services, employment opportunities, and community support to residents and visitors in a growing county.	Government Administration	🇺🇸 Fort Myers	2,185	1887
8	Soma soma.com A company founded in 2004 creates beautiful bra solutions for women, embodying the journey of women supporting women	Retail	🇺🇸 Fort Myers	1,957	2004
9	NeoGenomics Laboratories neogenomics.com Specializes in cancer genetics testing and oncology data solutions, providing diagnostic and predictive testing for cancer diagnosis and treatment.	Hospitals and Health Care	🇺🇸 Fort Myers	1,777	2002
10	Millennium Physician Group millenniumphysician.com A leading independent physician group offering comprehensive healthcare services across the Southeast, focused on primary care with specialties, wellness programs, and hospital care	Hospitals and Health Care	🇺🇸 Fort Myers	1,499	2008
11	Florida SouthWestern State College fsw.edu Institution offering affordable higher education programs with career-focused degrees, certifications, and intercollegiate athletics, serving nearly 22,000 students globally	Higher Education	🇺🇸 Fort Myers	1,047	1962
12	Lee County Sheriff's Office sheriffleefl.org Law enforcement agency in Lee County, Florida, responsible for enforcing state laws and maintaining public safety through certified law enforcement officers	Law Enforcement	🇺🇸 Fort Myers	946	n/a
13	21st Century Oncology genesiscareus.com The company provides personalized cancer treatments tailored to individual patient needs through a multidisciplinary approach	Medical Practices	🇺🇸 Fort Myers	938	n/a
14	American Oncology Network aoncology.com AON is a physician-led network focused on supporting community oncology practices, enhancing patient care, and enabling practice growth through diversification and scale	Medical Practices	🇺🇸 Fort Myers	593	2017
15	Elite DNA Behavioral Health elitedna.com A leading mental health provider in Florida offering comprehensive services for individuals, families, and substance abuse treatments, with a focus on holistic and personalized care	Mental Health Care	🇺🇸 Fort Myers	567	2013
16	Shell Point Retirement Community shellpoint.org A Florida-based retirement community offering independent living, skilled nursing, assisted living, amenities, services, and competitive compensation packages for employees	Hospitals and Health Care	🇺🇸 Fort Myers	530	1968
17	Allyn International allynintl.com Specializes in transportation management, logistics sourcing, supply chain consulting, and tax and trade compliance for global clients.	Transportation, Logistics, Supply Chain and Storage	🇺🇸 Fort Myers	524	1992
18	Arietis Health arietishealth.com Specializing in patient-focused, data-driven revenue cycle solutions for healthcare organizations, enhancing revenue, security, compliance, and business excellence	Hospitals and Health Care	🇺🇸 Fort Myers	491	2020
19	B&I Contractors Inc.bandiflorida.com A full-service mechanical, electrical, and plumbing contractor specializing in commercial, institutional, and industrial construction, restoration, and service, established in 1960	Construction	🇺🇸 Fort Myers	439	n/a
20	Juniper junipercares.com A leading landscaping company in South Florida offering design, construction, and maintenance services with a commitment to quality and customer satisfaction	Landscaping Services	🇺🇸 Fort Myers	425	2001
21	ADDMAN addmangroup.com The company focuses on enhancing the product lifecycle through a customer-centered and engineering-driven approach using additive manufacturing technology	Industrial Machinery Manufacturing	🇺🇸 Fort Myers	407	2020
22	City of Fort Myers cityftmyers.com A historic city in Southwest Florida providing exceptional municipal services while preserving rich history, culture, and lifestyle for residents and visitors	Government Administration	🇺🇸 Fort Myers	359	1886
23	Hope Healthcare hopehcs.org Hope offers comprehensive care and support for adults and children facing serious illness, aging, and end-of-life issues in southwest Florida	Hospitals and Health Care	🇺🇸 Fort Myers	357	1979
24	SRMS dreamababy.com A reproductive endocrinology practice offering a wide range of services including IVF, egg donation, surrogacy, genetics, and menopausal treatment	Medical Practices	🇺🇸 Fort Myers	353	1991
25	Radiology Regional Center radiologyregional.com A leading diagnostic imaging provider in the Southeast US, offering state-of-the-art outpatient centers, subspecialty-trained radiologists, and exceptional patient care	Medical Practices	🇺🇸 Fort Myers	333	1970
26	Lee County Port Authority flylcpa.com The company provides innovative solutions and cutting-edge technology to help businesses improve their operations and achieve their goals	Airlines and Aviation	🇺🇸 Fort Myers	329	1983
27	Royal Shell Real Estate, Inc.royalshellrealestate.com A team of experienced Southwest Florida realty professionals helping clients find their vision of paradise with unparalleled value, service, speed, and efficiency	Real Estate	🇺🇸 Fort Myers	319	1996
28	Robb & Stucky - Furniture and Interiors robbstucky.com Luxury home furnishings retailer providing professional interior design services, partnering with top furniture makers and offering innovative styles in home interiors	Retail	🇺🇸 Fort Myers	302	1915
29	VIP Realty Group Inc.viprealty.com A group of Realtors in SW Florida offering specialized agents for buying and selling properties, guiding clients through the search process	Real Estate	🇺🇸 Fort Myers	295	n/a
30	WINK News winknews.com A Southwest Florida media company with a long history, WINK News provides extensive news coverage through radio and television broadcasts	Broadcast Media Production and Distribution	🇺🇸 Fort Myers	183	1939
31	Family Health Centers of Southwest Florida fhcswfl.org A not-for-profit organization providing healthcare services in multiple counties, with a focus on serving all patients regardless of income status	Hospitals and Health Care	🇺🇸 Fort Myers	182	1977
32	GHRR (Now DISA Global Solutions)ghrr.com Leading employment screening experts providing pre-hire intelligence solutions such as background screening, substance abuse testing, and electronic onboarding for 5000+ clients	Human Resources Services	🇺🇸 Fort Myers	175	2005
33	20th Judicial Circuit Administrative Office of the Courts ca.cjis20.org Judicial circuit in Florida covering Charlotte, Collier, Glades, Hendry, and Lee counties, overseeing legal matters and court proceedings in the region	Government Administration	🇺🇸 Fort Myers	171	1973
34	Riverside Church riversidechurch.org We exist to create followers who embody the teachings and qualities of Jesus, fostering love and righteous living	Religious Institutions	🇺🇸 Fort Myers	170	n/a
35	Unilene SAC unilene.com Manufacturer of medical devices, specializing in sutures, with advanced technology in a quality-controlled laboratory and FDA/CE approvals for global markets	Medical Equipment Manufacturing	🇺🇸 Fort Myers	169	1995
36	Goodwill Southwest Florida goodwillswfl.org A nonprofit organization providing programs and services for people with disabilities and disadvantages to achieve independence and employment opportunities in Southwest Florida	Non-profit Organizations	🇺🇸 Fort Myers	162	1966
37	AIM Engineering & Surveying, Inc.aimengineering.com A full-service planning, engineering, and surveying company in Florida, offering innovative, cost-effective solutions with a focus on integrity and quality	Civil Engineering	🇺🇸 Fort Myers	159	1980
38	Lee County Tax Collector leetc.com A customer-focused tax collection agency dedicated to serving Lee County residents with community involvement at its core	Government Administration	🇺🇸 Fort Myers	153	n/a
39	Cypress Cove cypressliving.org A premier Continuing Care Retirement community offering top quality medical care and a dynamic team dedicated to excellence and growth Apply now!	Hospitals and Health Care	🇺🇸 Fort Myers	150	1998
40	SalusCare, Inc.saluscareflorida.org A not-for-profit mental health and substance abuse service provider in Southwest Florida offering affordable care, accepting various forms of payment and insurance	Hospitals and Health Care	🇺🇸 Fort Myers	149	2013
41	Henderson, Franklin, Starnes & Holt, P.A.henlaw.com A historic and reputable law firm serving Southwest Florida with personalized service from over 55 experienced attorneys	Law Practice	🇺🇸 Fort Myers	148	1924
42	Crowther Roofing and Cooling crowther.net A leader in roof repair, replacement, HVAC services for commercial/residential buildings in South/Southwest Florida Also offers cleaning and maintenance programs	Construction	🇺🇸 Fort Myers	146	1974
43	Saminco Solutions samincoinc.com Designs and manufactures AC and DC drives for electric vehicles, mining equipment, industrial controls, retrofits/rebuilds, and provides repair services for various brands	Appliances, Electrical, and Electronics Manufacturing	🇺🇸 Fort Myers	41	1992
44	Extropy Advisors Boutique consulting firm specializing in Financial Digital Transformation and Spend Management, helping organizations achieve exceptional performance and continuous improvement	Business Consulting and Services	🇺🇸 Fort Myers	41	2014
45	Nationwide Lift Trucks Inc toyotanlt.com A machinery company located in Hollywood, FL specializing in lift trucks for nationwide distribution and servicing	Machinery Manufacturing	🇺🇸 Fort Myers	29	n/a
46	Dona Jo donajobrand.com Fashionable, high-quality sportswear for women of all ages, specializing in unique prints and colors Committed to promoting a healthy and active lifestyle	Retail Apparel and Fashion	🇺🇸 Fort Myers	25	2013
47	OMNI Financial Services omnifinserv.com A trusted Florida-based company specializing in risk management and personal planning, dedicated to helping small and mid-sized organizations achieve their financial goals	Financial Services	🇺🇸 Fort Myers	25	1980
48	SAFRAN OIL SYSTEMS, LLC An aviation component design and manufacturing company located in Fort Myers, Florida, specializing in oil systems for the industry	Aviation and Aerospace Component Manufacturing	🇺🇸 Fort Myers	21	2009
49	Limitless Business limitlessbusiness.com This company helps business owners accelerate growth, optimize performance, and prepare for successful exits through their Scale-to-Sale Framework	Business Consulting and Services	🇺🇸 Fort Myers	16	n/a
50	Sheppard Law Firm sbshlaw.com Established in 1924, Sheppard Law Firm in Fort Myers and Naples, Florida offers legal services in estate planning, probate, asset protection, real estate, business, and banking law	Law Practice	🇺🇸 Fort Myers	15	1924
51	Neptune Technologies Inc.neptunetechnologies.com Innovative financial solutions company specializing in AI and blockchain technologies for retail investors, financial advisors, and institutions Focus on security and scalability	Software Development	🇺🇸 Fort Myers	14	2023
52	Phase V Fulfillment phasev.com A turnkey fulfillment solution provider offering order placement, kitting, inventory management, shipping, tracking, reporting, warehousing, logistics, customer service, and direct mail services	Transportation, Logistics, Supply Chain and Storage	🇺🇸 Fort Myers	14	n/a
53	Pepitone Properties Corp.pepitonerealty.com A full-service commercial real estate management firm in SW Florida and Tampa to Fort Lauderdale, specializing in receivership, leasing, sales, development, and renovations	Leasing Non-residential Real Estate	🇺🇸 Fort Myers	11	1996
54	Electron Charger electroncharger.com This company specializes in electric vehicle charging technology and manufacturing, offering solutions for various sectors such as Multi-Family, Hotels, and Real Estate	Electrical Equipment Manufacturing	🇺🇸 Fort Myers	10	2021

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Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Oct 24, 2026.

The same list elsewhere in United States

The largest companies in the United States 91,669
The largest companies in California 12,813
The largest companies in New York State 10,485
The largest companies in Texas 8,086
The largest companies in Florida 4,945
The largest companies in Illinois 4,175
The largest companies in Pennsylvania 3,110
The largest companies in Massachusetts 3,093
The largest companies in Georgia 2,632
The largest companies in Ohio 2,618
The largest companies in New Jersey 2,569
The largest companies in Virginia 2,503
The largest companies in Michigan 2,346
The largest companies in North Carolina 2,174
The largest companies in Alabama 1,806
The largest companies in Washington State 1,785
The largest companies in Colorado 1,774
The largest companies in Minnesota 1,700
The largest companies in Maryland 1,527
The largest companies in Wisconsin 1,482
The largest companies in New York 6,920
The largest companies in San Francisco 2,030
The largest companies in Houston 1,791
The largest companies in Chicago 1,668