The 49 largest companies in Roanoke (2026 list)

#	Company	Industry	Headquarters	Employees	Founded
1	Carilion Clinic carilionclinic.org Non-profit healthcare organization serving nearly one million Virginians through hospitals, specialty centers, primary care, medical education, and research.	Hospitals and Health Care	🇺🇸 Roanoke	8,963	1899
2	Roanoke City Public Schools rcps.info Roanoke City Public Schools empowers students through inclusive, student-centered education to fulfill their potential and benefit the community	Education	🇺🇸 Roanoke	1,650	n/a
3	Vera Bradley verabradley.com This company is dedicated to bringing beauty to women's lives through inspired luggage and supporting breast cancer research	Retail Apparel and Fashion	🇺🇸 Roanoke	1,424	1982
4	Roanoke County Schools rcps.us A public school system in Roanoke County, Virginia, providing education to students from pre-kindergarten through 12th grade	Primary and Secondary Education	🇺🇸 Roanoke	1,210	n/a
5	United State Postal Service A consumer services company based in Virginia, USA that is involved in postal services and delivery operations	Consumer Services	🇺🇸 Roanoke	1,133	n/a
6	Medical Facilities of America mfa.net Provider of progressive and transitional healthcare services, including inpatient rehab therapy, to help patients recover and return home faster Operating in various locations	Hospitals and Health Care	🇺🇸 Roanoke	1,026	1972
7	Virginia Transformer Corp vatransformer.com Engineering and manufacturing custom power transformers from 500 kVA to 1,400 MVA for utility, industrial, transit, and alternative energy markets worldwide using six facilities.	Manufacturing	🇺🇸 Roanoke	997	1971
8	City of Roanoke, VA roanokeva.gov Provides public services, outdoor recreation, and urban development within a mountain city hub featuring extensive trail networks, parks, and vibrant neighborhoods.	Government Administration	🇺🇸 Roanoke	956	1884
9	Home Depot Distribution Ctr careers.homedepot.com A logistics and supply chain company in Texas that specializes in distribution services for home improvement products	Transportation, Logistics, Supply Chain and Storage	🇺🇸 Roanoke	806	n/a
10	Virginia Western Community College virginiawestern.edu A public community college in Virginia offering two-year educational programs, with a campus in Roanoke and tuition support from a nonprofit foundation	Higher Education	🇺🇸 Roanoke	602	1966
11	Hollins University hollins.edu Empowering women through leadership training, writing opportunities, study abroad programs, and internships to prepare them for successful careers	Higher Education	🇺🇸 Roanoke	538	1842
12	ALCOVA Mortgage alcova.com ALCOVA Mortgage simplifies the homebuying process with convenient online applications, personalized service, and a customer-first approach to finding the best loan options	Financial Services	🇺🇸 Roanoke	517	2003
13	FAMILY PRESERVATION SERVICES clarvida.com Provider of community-based mental and behavioral health services in Virginia, committed to promoting positive change in individuals, families, and communities	Mental Health Care	🇺🇸 Roanoke	512	n/a
14	Brown Edwards becpas.com Professional business advisory and consulting firm offering tax, accounting, IT services, with expertise in education, municipalities, employee benefits, and more	Accounting	🇺🇸 Roanoke	480	1967
15	Virginia Tech Carilion School of Medicine medicine.vtc.vt.edu Innovative medical school and research institute merging Virginia Tech's strengths with Carilion Clinic's expertise to develop physician leaders and advance biomedical science	Higher Education	🇺🇸 Roanoke	440	2008
16	New River Electrical Corporation newriverelectrical.com Specializing in various electrical services, including substation construction and maintenance, transmission and distribution, industrial services, instrumentation, and storm restoration Serving customers nationally	Construction	🇺🇸 Roanoke	440	1953
17	Branch branchgroup.com A mid-Atlantic construction company offering services such as construction management, design-build, site development, and metal fabrication, with a focus on quality and community relationships	Construction	🇺🇸 Roanoke	433	1963
18	I'm Only Human getbreeze360.com This company offers a lighthearted perspective on human resources and workplace antics through its content	Book and Periodical Publishing	🇺🇸 Roanoke	376	2015
19	Goodwill Industries of the Valleys goodwillvalleys.com A nonprofit organization with a mission to empower individuals through skills training, job placement, and support services in various Virginia regions	Non-profit Organizations	🇺🇸 Roanoke	352	1931
20	Macado's macados.net A restaurant chain with eclectic decor and a wide array of sandwiches, subs, and entrees, popular among college students and business professionals	Restaurants	🇺🇸 Roanoke	343	n/a
21	CARILION ROANOKE MEMORIAL HOSPITAL A hospital and healthcare company located in Roanoke, Virginia, providing medical services to the community	Hospitals and Health Care	🇺🇸 Roanoke	318	n/a
22	American HealthCare, LLC - Heritage Hall Healthcare and Rehabilitation Centers heritage-hall.org A healthcare company focuses on providing quality nursing and rehabilitation services to seniors and diverse populations with compassion and dignity	Hospitals and Health Care	🇺🇸 Roanoke	310	1975
23	Blue Ridge Behavioral Healthcare brbh.org A community services board providing mental health, developmental disability, and substance use disorder services in the Roanoke Valley of Virginia	Mental Health Care	🇺🇸 Roanoke	310	1969
24	LUNA Innovations lunainc.com Leader in optical technology, specializing in high-performance fiber-optic-based products for various industries such as aerospace, defense, transportation, and communications Accelerating innovative technologies to market	Appliances, Electrical, and Electronics Manufacturing	🇺🇸 Roanoke	309	1990
25	Arby S Roast Beef Restaur This company specializes in serving slow-roasted roast beef, turkey, and premium Angus beef sandwiches sliced fresh daily at their sandwich shops	Warehousing and Storage	🇺🇸 Roanoke	302	n/a
26	Optical Cable Corporation occfiber.com A leading manufacturer of high-performance cabling systems for various industries, providing reliable connectivity solutions for critical applications in challenging environments	Telecommunications	🇺🇸 Roanoke	255	1983
27	Alliance Consumer Group acgbrands.com A multi-national consumer goods company based in Fort Worth, Texas, that owns brands specializing in lighting, tools, knives, pest defense, and personal heating products	Manufacturing	🇺🇸 Roanoke	193	1974
28	Member One memberonefcu.com A member-owned financial institution headquartered in Roanoke, Virginia, serving over 143,000 members with assets over $15 billion	Financial Services	🇺🇸 Roanoke	185	1940
29	Valcom Inc valcom.com A leading company specializing in electronics, telecommunication systems, loudspeaker paging, IP Mass Notification Systems, and Visual messaging for various industries and organizations	Telecommunications	🇺🇸 Roanoke	182	1977
30	The Roanoke Times roanoke.com A leading news provider in Southwest Virginia, offering award-winning news coverage, innovative advertising solutions, and a diverse, passionate team creating impactful stories	Newspaper Publishing	🇺🇸 Roanoke	180	1886
31	SFCS Architects sfcs.com A full-service architectural and engineering firm with over 90 years of experience, specializing in designs for Senior Living, Higher Education, and Civic/Public clients nationwide	Architecture and Planning	🇺🇸 Roanoke	178	1920
32	MKB, REALTORS®mkbrealtors.com Full-service real estate firm offering residential and commercial sales, property management, relocation services, and in-house mortgage solutions through a trusted network	Real Estate	🇺🇸 Roanoke	177	1973
33	Delta Dental of Virginia deltadentalva.com Dynamic dental benefits company focused on improving oral health with affordable plans, extensive provider network, and emphasis on team values and professional growth	Insurance	🇺🇸 Roanoke	177	1964
34	Freedom First Credit Union freedomfirst.com A community-focused financial institution in Roanoke, VA, prioritizing giving back to its members and the community, with a mission of helping people prosper	Financial Services	🇺🇸 Roanoke	176	1956
35	DePaul Community Resources depaulcr.org A nonprofit organization in Central and Southwest Virginia that transforms the lives of children, adults, and families with special needs	Non-profit Organizations	🇺🇸 Roanoke	172	1977
36	Gentry Locke gentrylocke.com A dynamic law firm providing responsive legal services for businesses, offering expertise in transactional work, litigation, and national/international support	Law Practice	🇺🇸 Roanoke	166	1923
37	Friendship Retirement Community friendship.us A world-class community offering a range of services for active adults and rehabilitation patients, including independent living, therapy, memory care, and skilled nursing	Hospitals and Health Care	🇺🇸 Roanoke	158	1966
38	CMR Institute \| USA cmrinstitute.org Specializing in pharmaceutical and medical device training, we offer customized learning pathways curated by industry experts to advance knowledge and drive performance	Education Administration Programs	🇺🇸 Roanoke	153	1966
39	Fink's Jewelers finks.com A family-owned company offering a wide selection of fine jewelry, luxury collections, and Swiss timepieces across multiple locations with exceptional customer service	Retail	🇺🇸 Roanoke	152	n/a
40	North Cross School northcross.org An independent college-preparatory school founded in 1944, offering a rigorous academic curriculum and promoting personal integrity, leadership, and community service	Primary and Secondary Education	🇺🇸 Roanoke	148	1944
41	Tom Thumb Food & Pharmacy Online grocery shopping platform providing health information, recipes, and meal ideas for customers to browse and purchase groceries	Retail	🇺🇸 Roanoke	148	n/a
42	One Resource Group orgcorp.com A team providing comprehensive insurance services, specializing in life, long term care, disability, critical illness, and annuities with industry-leading knowledge and innovation	Insurance	🇺🇸 Roanoke	86	2002
43	KlariVis klarivis.com A financial management tool offering real-time data for informed decision-making, empowering strategic insights, and tailored solutions for customers in banking	Software Development	🇺🇸 Roanoke	68	2019
44	Metis metisrisk.com A leading provider of risk management solutions in the insurance sector, offering tailored insurance products, claims handling, and risk management services	Insurance	🇺🇸 Roanoke	62	1998
45	Innovative Insurance thinkinnovative.net Specializing in health insurance and financial protection, we at Innovative Insurance strive to assist clients, add value, and improve our community	Insurance	🇺🇸 Roanoke	36	2015
46	Dominion Risk Advisors domrisk.com Providing expert risk management and insurance advice, analyzing risks, and offering practical solutions to protect businesses from emerging challenges	Insurance	🇺🇸 Roanoke	14	2010
47	Valley Bank jra-assessment.com A community bank focused on forming lasting relationships with customers by surpassing expectations and offering distinctive financial products and services	Banking	🇺🇸 Roanoke	13	1995
48	Oohllaa Oohllaa.com Specializing in tailored Internet advertising solutions, we help businesses acquire new clients through online marketing strategies like SEO, social media, and email campaigns	Advertising Services	🇺🇸 Roanoke	6	2014
49	PMI Payroll-Insurance-HR wedopayroll.com Company delivers comprehensive payroll, time and labor, insurance, HR, and talent management solutions with a focus on personalized customer service	Human Resources Services	🇺🇸 Roanoke	5	2003

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How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Oct 24, 2026.

The same list elsewhere in United States

The largest companies in the United States 91,669
The largest companies in California 12,813
The largest companies in New York State 10,485
The largest companies in Texas 8,086
The largest companies in Florida 4,945
The largest companies in Illinois 4,175
The largest companies in Pennsylvania 3,110
The largest companies in Massachusetts 3,093
The largest companies in Georgia 2,632
The largest companies in Ohio 2,618
The largest companies in New Jersey 2,569
The largest companies in Virginia 2,503
The largest companies in Michigan 2,346
The largest companies in North Carolina 2,174
The largest companies in Alabama 1,806
The largest companies in Washington State 1,785
The largest companies in Colorado 1,774
The largest companies in Minnesota 1,700
The largest companies in Maryland 1,527
The largest companies in Wisconsin 1,482
The largest companies in New York 6,920
The largest companies in San Francisco 2,030
The largest companies in Houston 1,791
The largest companies in Chicago 1,668