The 100 largest companies in Saint Paul (2026 list)

#	Company	Industry	Headquarters	Employees	Founded
1	3M 3m.com A company using science and technology to improve people's lives, making the impossible possible	Industrial Machinery Manufacturing	🇺🇸 Saint Paul	63,807	1902
2	State of Minnesota mn.gov Employs over 50,000 people across 100+ agencies, impacting Minnesotans through policy, safety, environment, and social services statewide.	Government Administration	🇺🇸 Saint Paul	59,508	n/a
3	Ecolab ecolab.com A global leader providing water, hygiene, and infection prevention solutions for various industries worldwide through comprehensive services and personalized insights	Chemical Manufacturing	🇺🇸 Saint Paul	48,879	n/a
4	Patterson Companies, Inc.pattersoncompanies.com Strengthening oral and animal health markets in North America and the United Kingdom, guiding customers with bold solutions, providing expertise, products, technologies, and services.	Medical Equipment Manufacturing	🇺🇸 Saint Paul	5,916	1877
5	St. Jude Medical cardiovascular.abbott Global medical device manufacturer transforming treatment for epidemic diseases with cost-effective technologies, focusing on cardiac, cardiovascular, and neuromodulation products.	Medical Equipment Manufacturing	🇺🇸 Saint Paul	5,896	1976
6	Macalester College macalester.edu Established in 1874, this company offers education to cultivate successful and ethical leaders through passionate teaching and nationally recognized scholarship	Higher Education	🇺🇸 Saint Paul	4,076	1874
7	University of St. Thomas stthomas.edu Private university in Minnesota offering values-based education, career preparation, and degrees in over 100 fields Emphasis on moral leadership and critical thinking	Higher Education	🇺🇸 Saint Paul	4,033	1885
8	Regions Hospital healthpartners.com A private, nonprofit teaching hospital in St Paul providing outstanding healthcare services including trauma care for adults and children	Hospitals and Health Care	🇺🇸 Saint Paul	3,821	1872
9	Patterson Dental pattersondental.com Provides dental practices with products, equipment, software, and services, acting as a trusted partner for oral health professionals since 1877.	Medical Equipment Manufacturing	🇺🇸 Saint Paul	3,352	1877
10	Ramsey County ramseycountymn.gov This company in Ramsey County employs over 4,000 people in various fields such as Health, Safety, Information, Economic Growth, and Community Investment	Government Administration	🇺🇸 Saint Paul	3,171	1849
11	Securian Financial securian.com Providing innovative insurance and retirement products through partnerships to help individuals, families, and businesses secure their financial futures.	Financial Services	🇺🇸 Saint Paul	3,084	1880
12	Saint Paul Public Schools spps.org Minnesota's second-largest school district, serving over 38,000 students with diverse backgrounds and offering innovative education programs supported by dedicated staff and community	Education Administration Programs	🇺🇸 Saint Paul	2,965	1856
13	Johnson Brothers johnsonbrothers.com A family-owned distributor of wine, spirits, and beer based in Minnesota, providing exceptional service and career opportunities in multiple functions	Beverage Manufacturing	🇺🇸 Saint Paul	2,491	1953
14	St. Catherine University stkate.edu A premier baccalaureate college for women offering undergraduate, graduate, and associate programs embracing diversity, reflection, and systemic change through liberal arts education	Higher Education	🇺🇸 Saint Paul	1,894	1905
15	Bethel University bethel.edu A longstanding institution offering a blend of evangelical faith and top-ranked academics through undergraduate, graduate, and seminary programs in Minnesota and online	Higher Education	🇺🇸 Saint Paul	1,891	1871
16	Minnesota Department of Human Services mn.gov A government agency in Minnesota provides essential services to vulnerable residents through a dedicated workforce offering a variety of career opportunities	Government Administration	🇺🇸 Saint Paul	1,870	n/a
17	Minnesota Department of Transportation dot.state.mn.us The company plans, builds, operates, and maintains safe and efficient transportation modes for Minnesotans and travelers to reach their destinations	Government Administration	🇺🇸 Saint Paul	1,794	n/a
18	Harris harriscompany.com National mechanical contractor providing design, engineering, construction, controls, service, manufacturing, conveyors, and building systems solutions with over 70 years of experience	Construction	🇺🇸 Saint Paul	1,794	1948
19	Minnesota Department of Health health.state.mn.us Public health system in Minnesota, working with local agencies and tribal governments to protect and improve the health of all residents	Government Administration	🇺🇸 Saint Paul	1,792	n/a
20	Retired homehelpershomecare.com A leading franchise providing comprehensive home care for seniors, new mothers, and those needing ongoing assistance, along with 24/7 medical alert systems	Hospitals and Health Care	🇺🇸 Saint Paul	1,724	2015
21	Metro State University metrostate.edu A public comprehensive university in the Twin Cities offering high-quality, affordable education with over 50 undergraduate degrees, customizable programs, and advanced degrees	Higher Education	🇺🇸 Saint Paul	1,596	1971
22	City of Saint Paul stpaul.gov Local government agency focused on equitable public services, cultural preservation, and diverse career opportunities across multiple departments.	Government Administration	🇺🇸 Saint Paul	1,408	1854
23	Minnesota IT Services mn.gov Minnesota IT Services is the IT agency for Minnesota's executive branch, providing IT services to over 70 agencies, boards, and commissions	IT Services and IT Consulting	🇺🇸 Saint Paul	1,347	n/a
24	Gillette Children's gillettechildrens.org Specializing in brain, bone, and movement conditions starting in childhood, we provide research, treatment, and technologies for children to thrive	Hospitals and Health Care	🇺🇸 Saint Paul	1,313	1897
25	Ellie Mental Health elliementalhealth.com This company offers a wide range of mental health services including counseling, therapy, medication management, psychological testing, and online therapy in Minnesota	Mental Health Care	🇺🇸 Saint Paul	1,305	2015
26	Metropolitan Council of the Twin Cities metrocouncil.org Coordinate transit systems, manage wastewater treatment, plan parks, oversee water resources, and administer housing funds for Twin Cities region.	Government Administration	🇺🇸 Saint Paul	1,296	n/a
27	Sagitec Solutions sagitec.com A leading software platform provider specializing in complex problem-solving for various industries through low-code/no-code solutions and extensive domain experience	Software Development	🇺🇸 Saint Paul	1,281	2004
28	Lutheran Social Service of Minnesota lssmn.org A statewide non-profit social service organization in Minnesota offering services for children, youth, families, people with disabilities, and older adults Promotes dignity, safety, and hope	Non-profit Organizations	🇺🇸 Saint Paul	1,254	1865
29	Hamline University hamline.edu A Minnesota university offering a premier education rooted in liberal arts, Wesleyan values, and real-world experiences to cultivate extraordinary leaders	Higher Education	🇺🇸 Saint Paul	1,247	1854
30	Concordia University-St. Paul csp.edu A private Christ-centered institution offering over 100 degrees, flexible learning options, and top alumni employers for lifelong success	Higher Education	🇺🇸 Saint Paul	1,223	1893
31	Minnesota Department of Natural Resources dnr.state.mn.us A government agency in Minnesota conserving and managing natural resources, providing outdoor recreation opportunities and supporting sustainable quality of life	Government Administration	🇺🇸 Saint Paul	1,142	1971
32	SEH sehinc.com An engineering, architecture, planning, and science firm connecting clients to solutions for success in mobility, infrastructure, clean water, and more	Civil Engineering	🇺🇸 Saint Paul	1,099	1927
33	University of Northwestern – St. Paul unwsp.edu Biblically-based education institution offering flexible certificates and degrees since 1902, supporting busy adults with tailored curriculum	Higher Education	🇺🇸 Saint Paul	1,095	n/a
34	Marsden Services marsden.com A leading privately-held facility services organization offering janitorial, security, HVAC, emergency response, and facility management services nationwide since 1952	Facilities Services	🇺🇸 Saint Paul	997	1952
35	Bremer Bank, a division of Old National bremer.com The company partners with individuals in the food, economy, and community service sectors to strengthen and support local communities	Banking	🇺🇸 Saint Paul	994	1943
36	Goodwill-Easter Seals Minnesota goodwilleasterseals.org A leader in employment services in Minnesota, providing education, job training, and placement services to eliminate barriers to work and independence	Non-profit Organizations	🇺🇸 Saint Paul	898	1919
37	McGough mcgough.com Experienced general contractor with six generations of expertise, specializing in diverse construction projects from new builds to renovations	Construction	🇺🇸 Saint Paul	897	1956
38	The Emily Program emilyprogram.com This organization offers personalized eating disorder treatment for individuals of all ages and genders at various locations, with a focus on comprehensive care and support	Mental Health Care	🇺🇸 Saint Paul	889	1993
39	American Public Media Group americanpublicmedia.org Enriching minds and nourishing spirits through award-winning public radio programming and podcasts, serving communities in Minnesota and southern California	Broadcast Media Production and Distribution	🇺🇸 Saint Paul	889	1967
40	U.S. Bancorp Advisors usbank.com Offering a wide range of financial services including investment advisory, insurance, and merger & acquisition advisory, tailored to help clients achieve their financial goals	Financial Services	🇺🇸 Saint Paul	875	n/a
41	Minnesota Department of Corrections mn.gov The company employs staff in various positions in correctional facilities, community services, and central offices, prioritizing diversity and supporting veterans	Public Safety	🇺🇸 Saint Paul	847	n/a
42	Minnesota Department of Revenue revenue.state.mn.us Government agency managing Minnesota's revenue system, administering state tax laws, collecting $267 billion annually to fund public services	Government Administration	🇺🇸 Saint Paul	845	n/a
43	Minnesota Pollution Control Agency pca.state.mn.us Monitors environmental quality, enforces regulations, cleans spills, develops policy, supports education, and collaborates to prevent pollution and conserve resources.	Environmental Services	🇺🇸 Saint Paul	819	n/a
44	Hubbard Broadcasting, Inc.hubbardbroadcasting.com Family-owned broadcasting company with television and radio stations across the US, along with digital services, video content, and entertainment channel	Broadcast Media Production and Distribution	🇺🇸 Saint Paul	798	1923
45	INFRA naturalfoodretailers.com A cooperative of independent natural food retailers in 45 states and Puerto Rico, providing support to help businesses thrive sustainably	Retail	🇺🇸 Saint Paul	787	2005
46	Minnesota Department of Employment and Economic Development validate.perfdrive.com An economic development agency in Minnesota focusing on business growth, workforce development, international trade, and community development through various programs	Government Administration	🇺🇸 Saint Paul	763	n/a
47	Old Dutch Foods olddutchfoods.com This company has been providing high-quality, one-of-a-kind snacks for over 80 years, emphasizing freshness and care in every product	Food and Beverage Manufacturing	🇺🇸 Saint Paul	744	1934
48	Minnesota State Colleges and Universities minnstate.edu Large system of state colleges and universities in Minnesota, serving over 300,000 students and offering affordable education with high graduate job placement rates	Higher Education	🇺🇸 Saint Paul	716	n/a
49	Office of the Minnesota Attorney General ag.state.mn.us The company represents the State of Minnesota in legal matters, enforces consumer protection laws, and advocates for individuals and small businesses	Government Administration	🇺🇸 Saint Paul	689	n/a
50	Smart Care smartcaresolutions.com Smart Care offers nationwide solutions for commercial foodservice, refrigeration, warehouse/cold storage, and HVAC equipment Always seeking top talent Contact careers@smartcaresolutionscom	Facilities Services	🇺🇸 Saint Paul	637	1878
51	Ecolab, Purolite Resins puroliteresins.com Manufactures ion exchange resins, adsorbents, and advanced polymers for water treatment, power generation, and life sciences industries to solve complex process challenges.	Manufacturing	🇺🇸 Saint Paul	624	n/a
52	Antea Group USA anteagroup.es An international firm specializing in engineering & environmental consulting, offering solutions in EHS, sustainability, and more to clients worldwide	Environmental Services	🇺🇸 Saint Paul	617	n/a
53	Affinity Plus Federal Credit Union affinityplus.org A not-for-profit financial cooperative prioritizing people over profit, providing care, integrity, and adaptability to its members Insured by NCUA	Banking	🇺🇸 Saint Paul	609	1930
54	Skyline Exhibits skyline.com A trade show exhibit partner that creates award-winning experiences with modular structures, high-impact graphics, and comprehensive services, making brilliant design accessible	Events Services	🇺🇸 Saint Paul	607	1980
55	Dessert Holdings dessertholdings.com A Premium Dessert Company in North America, offering innovative and high-quality desserts to retail and food service customers through multiple subsidiary companies	Manufacturing	🇺🇸 Saint Paul	604	n/a
56	Saint Paul College-A Community and Technical College saintpaul.edu A community college in Saint Paul, Minnesota offering associate degrees, certificates, and diplomas in a variety of fields with a diverse student population	Higher Education	🇺🇸 Saint Paul	604	1910
57	Kemps LLC kemps.com A family-owned dairy company since 1914, Kemps produces wholesome dairy products to nourish families in the upper Midwest region	Food and Beverage Manufacturing	🇺🇸 Saint Paul	601	1914
58	College Possible collegepossible.org Non-profit organization providing college access and success support to under-represented students through coaching, curriculum, and partnerships, leading to higher enrollment and graduation rates	Non-profit Organizations	🇺🇸 Saint Paul	538	2000
59	Minnesota Historical Society mnhs.org A non-profit institution preserving and telling the story of Minnesota through exhibits, libraries, historic sites, educational programs, and book publishing	Museums, Historical Sites, and Zoos	🇺🇸 Saint Paul	518	1849
60	IP Corporation ip-corporation.com For over 40 years, our company has been a leading supplier of resins and composite materials to the composites industry through our subsidiaries	Chemical Manufacturing	🇺🇸 Saint Paul	514	n/a
61	American Security & Investigations americansecurityllc.com A leading security and investigative services provider in the upper midwest, offering tailored security solutions, technology integration, and total facilities management	Security and Investigations	🇺🇸 Saint Paul	510	1976
62	Vomela vomela.com A company specializing in designing and producing visual communications to create memorable brand experiences, with 1,300 employees across North America	Printing Services	🇺🇸 Saint Paul	507	1947
63	AgriBank, FCB agribank.com Agricultural cooperative in Twin Cities supporting rural America with finance, risk, and credit services, offering growth opportunities in a supportive culture	Banking	🇺🇸 Saint Paul	489	1916
64	Bluum linktr.ee Partnering with school districts to implement and optimize K-12 technology, enhancing student learning experiences and educational outcomes.	IT Services and IT Consulting	🇺🇸 Saint Paul	483	1946
65	St. Thomas More Catholic School morecommunity.org A student-centered Catholic school focusing on faith, service, and academic excellence to prepare students to be leaders in a changing world	Primary and Secondary Education	🇺🇸 Saint Paul	465	n/a
66	Augeo augeomarketing.com Global leader in engagement platform technologies, fostering connections and advocating brands worldwide through workplace engagement, experiential campaigns, social activation, and customer loyalty programs	Advertising Services	🇺🇸 Saint Paul	462	1999
67	Q3 Contracting Inc.q3contracting.com A construction contracting company specializing in gas, oil, electric, and telecommunications services, offering specific and turnkey solutions across multiple Midwest locations	Construction	🇺🇸 Saint Paul	459	n/a
68	Holiday Gas Station A Minnesota-based accounting firm located in Saint Paul, specializing in financial services for businesses, individuals, and organizations	Accounting	🇺🇸 Saint Paul	456	n/a
69	Wilder wilder.org Nonprofit organization in Saint Paul, MN providing health and human services to improve lives with compassion, action, and dedication to social welfare	Non-profit Organizations	🇺🇸 Saint Paul	455	1906
70	Mitchell Hamline School of Law mitchellhamline.edu A forward-thinking law school offering relevant legal education with exceptional practical training, preparing students for various legal career paths	Higher Education	🇺🇸 Saint Paul	438	1900
71	Minnesota Department of Public Safety - DPS dps.mn.gov A public safety department in Minnesota providing enforcement, service, funding, training, legislative development, and various divisions to strengthen public safety infrastructure	Public Safety	🇺🇸 Saint Paul	436	n/a
72	Summit Fire Protection summitfire.com Provider of comprehensive fire protection and life safety solutions, including design, installation, inspections, testing, and maintenance services to protect buildings from fire and intrusion	Fire Protection	🇺🇸 Saint Paul	410	1999
73	Interplastic Corporation interplastic.com A specialty chemical company based in St Paul, MN, focusing on producing and selling resins, gel coats, putties, and colorants for composites and cast polymer industries	Chemical Manufacturing	🇺🇸 Saint Paul	410	1959
74	Minnesota Wild nhl.com Professional hockey team competing in the NHL's Central Division, representing Minnesota and owned by Craig Leipold since 2000.	Spectator Sports	🇺🇸 Saint Paul	406	1997
75	Smarte Carte smartecarte.com The company offers self-serve luggage carts, lockers, strollers, and massage chairs at various locations worldwide with a focus on excellent service	Consumer Services	🇺🇸 Saint Paul	405	1967
76	AET teamaet.com Employee-owned consulting engineering company providing geotechnical, environmental, and materials engineering services nationwide, with expertise in building forensics and nondestructive testing	Civil Engineering	🇺🇸 Saint Paul	401	1971
77	Pheasants Forever and Quail Forever pheasantsforever.org A non-profit organization dedicated to wildlife conservation through habitat improvements, public awareness, education, and grassroots fundraising for local projects	Environmental Services	🇺🇸 Saint Paul	396	1982
78	EPSMR epsmr.org This Public Mental Health Establishment in Réunion provides prevention, hospitalization, and post-hospitalization care for patients in three health territories, serving over 540,000 inhabitants	Hospitals and Health Care	🇺🇸 Saint Paul	388	n/a
79	IC System icsystem.com A family-owned accounts receivable management provider offering ethical collections for consumer and commercial accounts with a focus on technology and innovation	Financial Services	🇺🇸 Saint Paul	386	1938
80	Koch Logistics kochlogistics.com A leading Third-Party Logistics company providing transportation, shipping, distribution, and warehousing services with a focus on customer service and integrity	Transportation, Logistics, Supply Chain and Storage	🇺🇸 Saint Paul	374	1992
81	Minnesota House of Representatives house.mn.gov This company is responsible for the enactment and revision of laws at both the national and state levels through a bicameral system	Government Administration	🇺🇸 Saint Paul	371	1858
82	Brown & Bigelow brownandbigelow.com A full service promotional products company providing brand-building merchandise and apparel for various companies, helping launch and nurture brands globally	Other	🇺🇸 Saint Paul	362	1896
83	Minnesota Oncology mnoncology.com Leading cancer treatment provider in the Twin Cities, offering access to over 100 experts, evidence-based treatment paths, comprehensive services, and 12 convenient locations	Hospitals and Health Care	🇺🇸 Saint Paul	360	1995
84	Science Museum of Minnesota new.smm.org The company is a science museum dedicated to educating, inspiring, and collaborating with the community to make lives better through science	Museums, Historical Sites, and Zoos	🇺🇸 Saint Paul	357	1907
85	Sunrise Banks sunrisebanks.com Innovative bank focused on financial wellness, community impact, and employee well-being through inclusive products, social initiatives, and sustainable partnerships globally	Banking	🇺🇸 Saint Paul	357	1962
86	Viking Fire Protection Group vfpfire.com Specializing in fire protection since 1927, providing systems and services nationwide with expertise in planning, engineering, installation, inspection, and maintenance	Construction	🇺🇸 Saint Paul	355	1927
87	ST. PAUL PUBLIC SCHOOL DISTRICT A primary/secondary education company located in Saint Paul, Minnesota providing educational services to students in the local community	Primary and Secondary Education	🇺🇸 Saint Paul	350	n/a
88	Minnesota Department of Agriculture mda.state.mn.us The company works towards enhancing quality of life in Minnesota by ensuring food supply integrity, environmental health, and agricultural economy strength	Government Administration	🇺🇸 Saint Paul	329	n/a
89	Minnesota Senate senate.mn The Minnesota Senate is the upper house of the Minnesota Legislature with 67 members, offering career opportunities through their website	Government Administration	🇺🇸 Saint Paul	321	n/a
90	Planned Parenthood North Central States ppncsorg Reproductive and sexual health organization providing high quality care, education, and advocacy in the Midwest, serving thousands of individuals annually	Hospitals and Health Care	🇺🇸 Saint Paul	315	n/a
91	Quasar Medical \| Medical Device Manufacturer quasarmedical.com Global leader in manufacturing minimally invasive medical components, devices, and micro-sensors for medical device companies worldwide with comprehensive turnkey solutions and global presence	Medical Equipment Manufacturing	🇺🇸 Saint Paul	314	1988
92	CLUES clues.org A Minnesota-based Latino-led nonprofit agency providing culturally relevant services to advance social and economic equity for the Latino community	Individual and Family Services	🇺🇸 Saint Paul	314	1981
93	FLS Connect flsconnect.com A political and constituent communication company focused on designing effective campaigns, training agents for quality communication, and using innovative technology to deliver targeted messages	Telecommunications	🇺🇸 Saint Paul	307	1999
94	Genesys Works Twin Cities genesysworks.org This organization provides high school students in underserved communities with skills training, work experiences, and support for career success and economic self-sufficiency	Non-profit Organizations	🇺🇸 Saint Paul	306	2008
95	Cardiovascular Systems, Inc.csi360.com Provides innovative medical devices for revascularization of complex coronary and peripheral artery disease, focusing on arterial calcium challenges to improve patient outcomes.	Medical Equipment Manufacturing	🇺🇸 Saint Paul	271	n/a
96	Cummins Sales & Service - Central Region cummins.com The company provides sales and services in the central region from its corporate headquarters in White Bear Lake, MN	Truck Transportation	🇺🇸 Saint Paul	240	n/a
97	The American Registry of Radiologic Technologists (ARRT)arrt.org The organization offers credentials in medical imaging, interventional procedures, and radiation therapy, advocating for safety and advancement in radiological sciences professions	Medical Practices	🇺🇸 Saint Paul	236	1922
98	St. Paul City School stpaulcityschool.org A public PreK-12 charter school district in St Paul, MN, empowering nearly 600 students academically and socially in a supportive community	Primary and Secondary Education	🇺🇸 Saint Paul	236	n/a
99	Memorial Blood Centers mbc.org An independent nonprofit providing life-saving blood to hospitals and partners, operating donor centers, conducting blood drives, and offering testing and technical services	Hospitals and Health Care	🇺🇸 Saint Paul	229	1948
100	Heraeus Medical Components bit.ly A contract development manufacturing organization that partners with medical device OEM teams to bring life-changing devices to market globally	Medical Equipment Manufacturing	🇺🇸 Saint Paul	228	n/a

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Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Oct 24, 2026.

The same list elsewhere in United States

The largest companies in the United States 91,669
The largest companies in California 12,813
The largest companies in New York State 10,485
The largest companies in Texas 8,086
The largest companies in Florida 4,945
The largest companies in Illinois 4,175
The largest companies in Pennsylvania 3,110
The largest companies in Massachusetts 3,093
The largest companies in Georgia 2,632
The largest companies in Ohio 2,618
The largest companies in New Jersey 2,569
The largest companies in Virginia 2,503
The largest companies in Michigan 2,346
The largest companies in North Carolina 2,174
The largest companies in Alabama 1,806
The largest companies in Washington State 1,785
The largest companies in Colorado 1,774
The largest companies in Minnesota 1,700
The largest companies in Maryland 1,527
The largest companies in Wisconsin 1,482
The largest companies in New York 6,920
The largest companies in San Francisco 2,030
The largest companies in Houston 1,791
The largest companies in Chicago 1,668