The 55 largest companies in Sioux Falls (2026 list)

#	Company	Industry	Headquarters	Employees	Founded
1	Sanford Health sanfordhealth.org Largest rural health system providing integrated medical centers, senior care, research, and global clinics serving over one million patients.	Hospitals and Health Care	🇺🇸 Sioux Falls	16,445	n/a
2	Avera Health avera.org Integrated health system providing compassionate care and wellness services across multiple states through numerous locations and dedicated employees.	Hospitals and Health Care	🇺🇸 Sioux Falls	6,285	n/a
3	Good Samaritan good-sam.com A not-for-profit provider of senior care and services, motivated by love and faith-based values, serving people of all beliefs	Hospitals and Health Care	🇺🇸 Sioux Falls	5,201	1922
4	RAS rascompanies.com An experienced workers' compensation insurance provider offering services to improve workplace safety, reduce costs, and support employees through proactive injury prevention measures	Insurance	🇺🇸 Sioux Falls	3,614	1989
5	Sioux Falls School District sf.k12.sd.us The Sioux Falls School District serves over 25,000 students, providing pathways for student success through education, preparation, and lifelong learning	Primary and Secondary Education	🇺🇸 Sioux Falls	2,067	1871
6	Avera McKennan Hospital & University Health Center locations.avera.org Avera Health is a large healthcare network providing high-quality clinical care in 82 communities through hospitals, clinics, and research centers	Hospitals and Health Care	🇺🇸 Sioux Falls	1,987	1911
7	POET poet.com POET develops renewable biofuels and bioproducts, providing clean energy solutions while boosting the economy and promoting sustainability and efficiency	Biotechnology Research	🇺🇸 Sioux Falls	1,917	1987
8	Pathward pathward.com The company focuses on expanding financial access through Banking-as-a-Service and commercial finance solutions to promote financial inclusion for all	Financial Services	🇺🇸 Sioux Falls	1,112	1954
9	Veterans Hospital A hospital and healthcare company located in Sioux Falls, South Dakota, specializing in providing medical care for veterans	Hospitals and Health Care	🇺🇸 Sioux Falls	998	n/a
10	The Bancorp thebancorp.com Provides specialized financial services including prepaid card issuance, SBA lending, securities-backed credit, and commercial vehicle leasing for non-bank companies.	Banking	🇺🇸 Sioux Falls	858	2000
11	Augustana University (SD)augie.edu Discover your potential at Augustana University through our diverse programs and supportive community Join us to be a part of #WeAreAU	Higher Education	🇺🇸 Sioux Falls	857	1860
12	Raven Industries ravenind.com A leading precision agriculture technology innovator helping farmers by reducing operating costs, connecting operations, and increasing sustainability through optimized inputs	Farming	🇺🇸 Sioux Falls	728	n/a
13	TAK Broadband takbroadband.com A nationally recognized Construction and Infrastructure Firm serving the Cable, Broadband, and Telecommunications industry with over 2,500 team members and partners	Telecommunications	🇺🇸 Sioux Falls	718	2004
14	SONIFI Solutions, Inc.sonifi.com Industry leader providing innovative guest experience solutions for hospitality and healthcare sectors, offering internet services, streaming, interactive TV, and nationwide technical support	Hospitality	🇺🇸 Sioux Falls	701	1980
15	gpac gogpac.com A recruitment and development company with over 30 years of experience, dedicated to matching top talent with the right companies	Staffing and Recruiting	🇺🇸 Sioux Falls	608	1990
16	LifeScape lifescapesd.org A company dedicated to empowering individuals to live their best life through innovative services, technology solutions, and collaborative partnerships, guided by integrity and compassion	Hospitals and Health Care	🇺🇸 Sioux Falls	526	1952
17	Billion Automotive billionauto.com A family-owned automotive business with 26 locations, offering career opportunities and comprehensive benefits to employees in multiple states	Motor Vehicle Manufacturing	🇺🇸 Sioux Falls	509	1935
18	BCBG Maxazria An entertainment company located in Sioux Falls, South Dakota, offering a range of services or products	Entertainment Providers	🇺🇸 Sioux Falls	501	n/a
19	Microstocksolutions microstocksolutions.com A digital asset content management company providing editing, keywording, metadata, video post-production, curation, legal review, brand consistency, and machine learning services efficiently	Technology, Information and Media	🇺🇸 Sioux Falls	469	2008
20	Midland National Life Insurance Company midlandnational.com Midland National Life Insurance provides life insurance and annuities to protect families, preserve legacies, and make long-term financial decisions with a focus on sustainability	Insurance	🇺🇸 Sioux Falls	464	1906
21	Remax Professionals inc.expireddomains.com Experienced real estate agency in Sioux Falls since 1985, known for top agents and high recognition Specializing in selling properties	Real Estate	🇺🇸 Sioux Falls	456	1985
22	Furniture Mart USA furnituremartusa.com Family-owned furniture retail operation with multiple store locations in upper Midwest offering high-quality furniture, mattresses, and accessories with exceptional customer service	Furniture and Home Furnishings Manufacturing	🇺🇸 Sioux Falls	435	1976
23	Five Star Solutions getfivestar.com A customer contact center outsourcer delivering exceptional experiences through passionate, authentic, and happy interactions, with solutions tailored to individual needs	Outsourcing and Offshoring Consulting	🇺🇸 Sioux Falls	396	1986
24	Southeast Tech southeasttech.edu Career-focused technical college offering over 70 programs, certificates, and apprenticeships with passionate faculty, utilizing Sioux Falls as an extended classroom for professional success in two years or less	Higher Education	🇺🇸 Sioux Falls	382	1968
25	University of Sioux Falls usiouxfalls.edu A Christian university offering education in liberal arts, sciences, and professions, focusing on academic excellence and developing mature Christian leaders for service	Higher Education	🇺🇸 Sioux Falls	370	1883
26	OTA weareota.com The company offers creative and collaborative initiatives to empower community-builders and change agents in South Dakota, North Dakota, and Minnesota	Civic and Social Organizations	🇺🇸 Sioux Falls	333	2009
27	C & B Material Handling burwellmh.com A family-owned company with multiple John Deere dealership locations and expanding into Material Handling and Powersports divisions while upholding core values	Machinery Manufacturing	🇺🇸 Sioux Falls	311	1988
28	MetaBank pathward.com A financial services company focusing on economic mobility and social responsibility, aiming to provide access to financial opportunities for all	Financial Services	🇺🇸 Sioux Falls	236	1954
29	The First National Bank in Sioux Falls fnbsf.com A community-focused bank offering financial services including accounts, loans, and wealth management, with a commitment to simplifying money matters through a podcast	Financial Services	🇺🇸 Sioux Falls	233	1885
30	Carsforsale.com carsforsale.com A leader in the online automotive industry, offering innovative software solutions and a powerful inventory system for dealers and a simplified car-shopping experience for buyers	Technology, Information and Internet	🇺🇸 Sioux Falls	205	1999
31	Aerostar (Aerostar International LLC)aerostar.com An Aerospace & Defense provider offering stratospheric platforms, radar sensors, technical services, and protective wear for successful operations and saving lives	Defense and Space Manufacturing	🇺🇸 Sioux Falls	195	n/a
32	Sioux Falls Specialty Hospital sfsh.com A physician-owned hospital offering innovative world-class surgery, recovery, imaging, pain management, and primary care with a focus on quality, safety, and patient comfort	Hospitals and Health Care	🇺🇸 Sioux Falls	180	1985
33	Sioux Steel Company siouxsteel.com Manufacturer of high-quality steel products, with a focus on longevity and customer value, offering industry-leading warranties and exceptional service worldwide	Farming	🇺🇸 Sioux Falls	180	1918
34	A&B Business Solutions abbusiness.com Facilitator for businesses providing services, products, and equipment to enhance efficiency and reliability, with 15 locations across five states	Printing Services	🇺🇸 Sioux Falls	180	1981
35	ALARIS Group Inc. is now Paradigm paradigmcorp.com An accountable specialty care management organization focused on improving the lives of people with complex and catastrophic injuries through value-based care solutions	Hospitals and Health Care	🇺🇸 Sioux Falls	175	1991
36	Wireless World wirelessworld.com Independently owned Verizon Authorized Retailer with locations in Iowa, South Dakota, Minnesota, Nebraska, and Wisconsin Offers top-rated service, upgrades, and bundle options	Wireless Services	🇺🇸 Sioux Falls	174	2001
37	SDN Communications sdncommunications.com Premier provider of business broadband services in the region, offering extensive fiber-optic network for voice, data, internet, and video services to businesses	Telecommunications	🇺🇸 Sioux Falls	166	1989
38	Profile Plan hmrprogram.com A physician and scientist-designed weight management program, Profile Plan offers a simple, effective, and sustainable solution with certified coaches	Wellness and Fitness Services	🇺🇸 Sioux Falls	164	2012
39	Building Products Inc.bpi.build A building materials distributor with offices in multiple states, focused on developing partnerships, fulfilling commitments, and upholding integrity	Wholesale	🇺🇸 Sioux Falls	161	1957
40	Get n Go getngo.com A leading convenience store chain with 19 locations, focused on growth, development of team members, and customer care for over 60 years	Retail	🇺🇸 Sioux Falls	155	n/a
41	RENEW takkion.com Premier service provider offering logistics, O&M, technical repair, and remanufacturing services to the renewable energy industry in North America	Services for Renewable Energy	🇺🇸 Sioux Falls	155	2009
42	California Intercontinental University caluniversity.edu Online university promoting quality learning and critical thinking to help students excel in their career goals and become successful business leaders	Higher Education	🇺🇸 Sioux Falls	150	1996
43	Sanford Health Plan sanfordhealthplan.com Provider-owned health plan offering affordable coverage in the upper Midwest with a network of expert providers and innovative care coordination NCQA accredited	Insurance	🇺🇸 Sioux Falls	150	1997
44	Eagle Construction eagledesignbuild.com This company provides professional services to bring creative concepts to life, drive economic growth in communities, and turn ideas into successful projects	Construction	🇺🇸 Sioux Falls	147	n/a
45	Malloy Electric malloyelectric.com Established in 1945, this company in the electrical and power transmission industry provides comprehensive solutions, emergency services, and customer-focused support	Industrial Machinery Manufacturing	🇺🇸 Sioux Falls	143	1945
46	Prismatic prismatic.io Prismatic offers a versatile embedded iPaaS solution for B2B SaaS teams to build, deploy, and support product integrations quickly and efficiently	Software Development	🇺🇸 Sioux Falls	73	2019
47	Coffea Roasterie & Espresso Bar coffearoasterie.com Specialty coffee roaster and retailer based in South Dakota, offering a variety of gourmet coffees and creating a community around coffee	Food and Beverage Services	🇺🇸 Sioux Falls	19	2009
48	Legacy Law Firm, P.C.legacylawfirmpc.com A boutique law firm specializing in estate planning, elder law, and business planning, dedicated to providing personalized services and staying updated on industry topics	Legal Services	🇺🇸 Sioux Falls	17	2016
49	Bird Dog Equity Partners, LLC birddogequity.com Private equity firm prioritizing people, integrity, and long-term relationships Focus on good deals with good people for mutual success	Venture Capital and Private Equity Principals	🇺🇸 Sioux Falls	9	2010
50	Lead to Inspire leadtoinspire.net The company focuses on helping individuals and organizations invest in their people through leadership development, employee engagement, and client experience improvement strategies	Professional Training and Coaching	🇺🇸 Sioux Falls	7	2016
51	Sioux Falls Software siouxfallssoftware.com The company provides a wide range of services including design, web/software development, SEO, ecommerce, data analysis, business intelligence, and web-to-print solutions	Software Development	🇺🇸 Sioux Falls	5	n/a
52	Cobra King cobra-king.com A company focused on investing in early-stage startups to provide financial support and help them grow and succeed in their respective industries	Investment Management	🇺🇸 Sioux Falls	5	2017
53	The Source Coffee Roastery + Taproom thesourcesf.com Specialty Coffee Roaster + Taproom offering world-class coffee, craft beer, and a friendly gathering place with a focus on quality and hospitality	Food and Beverage Services	🇺🇸 Sioux Falls	3	2017
54	AnMaur Enterprises, Inc. (JaLar Logistics Systems)jalarinc.com A full-service logistics provider specializing in customized 3PL solutions, utilizing cutting-edge technology for accurate communication and efficient freight coverage	Truck Transportation	🇺🇸 Sioux Falls	2	2015
55	Lean 5S Products U.S.A lean5sproducts.com Customized 5S lean visual management solutions for workplaces, including Cleaning Stations, Safety Boards, and Production Boards tailored to specific tooling requirements	Printing Services	🇺🇸 Sioux Falls	2	2016

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How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Oct 24, 2026.

The same list elsewhere in United States

The largest companies in the United States 91,669
The largest companies in California 12,813
The largest companies in New York State 10,485
The largest companies in Texas 8,086
The largest companies in Florida 4,945
The largest companies in Illinois 4,175
The largest companies in Pennsylvania 3,110
The largest companies in Massachusetts 3,093
The largest companies in Georgia 2,632
The largest companies in Ohio 2,618
The largest companies in New Jersey 2,569
The largest companies in Virginia 2,503
The largest companies in Michigan 2,346
The largest companies in North Carolina 2,174
The largest companies in Alabama 1,806
The largest companies in Washington State 1,785
The largest companies in Colorado 1,774
The largest companies in Minnesota 1,700
The largest companies in Maryland 1,527
The largest companies in Wisconsin 1,482
The largest companies in New York 6,920
The largest companies in San Francisco 2,030
The largest companies in Houston 1,791
The largest companies in Chicago 1,668