The 100 largest companies in South Dakota (2026 list)

#	Company	Industry	Headquarters	Employees	Founded
1	Sanford Health sanfordhealth.org Largest rural health system providing integrated medical centers, senior care, research, and global clinics serving over one million patients.	Hospitals and Health Care	🇺🇸 Sioux Falls	16,445	n/a
2	Sekolah sekolah.pk A one-stop online store for school kids' needs, offering courses, stationery, bags, lunch boxes, uniforms, and more, with delivery to your doorstep	Education Administration Programs	🇺🇸 Karachi	14,022	n/a
3	Avera Health avera.org Integrated health system providing compassionate care and wellness services across multiple states through numerous locations and dedicated employees.	Hospitals and Health Care	🇺🇸 Sioux Falls	6,285	n/a
4	Good Samaritan good-sam.com A not-for-profit provider of senior care and services, motivated by love and faith-based values, serving people of all beliefs	Hospitals and Health Care	🇺🇸 Sioux Falls	5,201	1922
5	South Dakota State University sdstate.edu Public university offering diverse undergraduate, graduate, and doctoral programs with extensive research activities and statewide educational outreach.	Higher Education	🇺🇸 Brookings	3,652	1881
6	RAS rascompanies.com An experienced workers' compensation insurance provider offering services to improve workplace safety, reduce costs, and support employees through proactive injury prevention measures	Insurance	🇺🇸 Sioux Falls	3,614	1989
7	State of South Dakota sd.gov State government promoting job opportunities, economic growth, and quality living through servant leadership, openness, and a business-friendly environment.	Government Administration	🇺🇸 Pierre	3,239	1889
8	University of South Dakota usd.edu A leading university in South Dakota offering diverse undergraduate, graduate, and professional programs focused on inclusiveness and liberal arts education	Higher Education	🇺🇸 Vermillion	2,487	1862
9	Monument Health monument.health A community-based health care system in western South Dakota and eastern Wyoming, offering care in 33 specialties with 5 hospitals and 40 medical clinics	Hospitals and Health Care	🇺🇸 Rapid City	2,454	1973
10	Black Hills Energy blackhillsenergy.com A vertically integrated energy enterprise serving 12 million utility customers in eight states, with non-regulated businesses in wholesale electricity and natural gas/coal production	Utilities	🇺🇸 Rapid City	2,220	1883
11	Sioux Falls School District sf.k12.sd.us The Sioux Falls School District serves over 25,000 students, providing pathways for student success through education, preparation, and lifelong learning	Primary and Secondary Education	🇺🇸 Sioux Falls	2,067	1871
12	Avera McKennan Hospital & University Health Center locations.avera.org Avera Health is a large healthcare network providing high-quality clinical care in 82 communities through hospitals, clinics, and research centers	Hospitals and Health Care	🇺🇸 Sioux Falls	1,987	1911
13	POET poet.com POET develops renewable biofuels and bioproducts, providing clean energy solutions while boosting the economy and promoting sustainability and efficiency	Biotechnology Research	🇺🇸 Sioux Falls	1,917	1987
14	Pathward pathward.com The company focuses on expanding financial access through Banking-as-a-Service and commercial finance solutions to promote financial inclusion for all	Financial Services	🇺🇸 Sioux Falls	1,112	1954
15	National American University national.edu A higher education institution offering flexible degree programs for working adults to achieve their educational goals through campus and online locations	Education Administration Programs	🇺🇸 Rapid City	1,030	1941
16	Veterans Hospital A hospital and healthcare company located in Sioux Falls, South Dakota, specializing in providing medical care for veterans	Hospitals and Health Care	🇺🇸 Sioux Falls	998	n/a
17	South Dakota Mines sdsmt.edu A leading institution in engineering and science education, offering award-winning undergraduate and graduate programs and conducting critical research and development	Higher Education	🇺🇸 Rapid City	978	1885
18	First Bank & Trust bankeasy.com Family- and employee-owned bank with 22 locations in South Dakota and Minnesota, offering community banking services and niche products nationwide	Financial Services	🇺🇸 Brookings	918	1880
19	The Bancorp thebancorp.com Provides specialized financial services including prepaid card issuance, SBA lending, securities-backed credit, and commercial vehicle leasing for non-bank companies.	Banking	🇺🇸 Sioux Falls	858	2000
20	Augustana University (SD)augie.edu Discover your potential at Augustana University through our diverse programs and supportive community Join us to be a part of #WeAreAU	Higher Education	🇺🇸 Sioux Falls	857	1860
21	Dakota State University dsu.edu An educational institution offering undergraduate, master's, and doctoral programs with a focus on computing, information technologies, and cybersecurity research and development	Higher Education	🇺🇸 Madison	842	1881
22	Primrose Retirement Communities, LLC primroseretirement.com Provider of high-quality independent and assisted living communities for seniors across the country, offering personalized services and resident-focused care since 1989	Hospitals and Health Care	🇺🇸 Aberdeen	741	1989
23	RESPEC respec.com A team of technology experts with vast experience and resourcefulness, solving complex problems with vision, knowledge, and superhero-like skills	Professional Services	🇺🇸 Rapid City	729	n/a
24	Raven Industries ravenind.com A leading precision agriculture technology innovator helping farmers by reducing operating costs, connecting operations, and increasing sustainability through optimized inputs	Farming	🇺🇸 Sioux Falls	728	n/a
25	TAK Broadband takbroadband.com A nationally recognized Construction and Infrastructure Firm serving the Cable, Broadband, and Telecommunications industry with over 2,500 team members and partners	Telecommunications	🇺🇸 Sioux Falls	718	2004
26	SONIFI Solutions, Inc.sonifi.com Industry leader providing innovative guest experience solutions for hospitality and healthcare sectors, offering internet services, streaming, interactive TV, and nationwide technical support	Hospitality	🇺🇸 Sioux Falls	701	1980
27	Rapid City Area Schools rcas.org Providing quality education in the Black Hills of South Dakota, the company aims to achieve excellence in student learning and success	Primary and Secondary Education	🇺🇸 Rapid City	700	n/a
28	Black Hills State University bhsu.edu A public liberal arts university founded in 1883, providing students and faculty with a world-class academic experience in the beautiful Black Hills	Higher Education	🇺🇸 Spearfish	664	1883
29	gpac gogpac.com A recruitment and development company with over 30 years of experience, dedicated to matching top talent with the right companies	Staffing and Recruiting	🇺🇸 Sioux Falls	608	1990
30	Northern State University northern.edu Small campus university offering rigorous academics, hands-on learning experiences, and internship opportunities in various fields, with a focus on student success and growth	Higher Education	🇺🇸 Aberdeen	574	1901
31	Lawrence County lawrence.sd.us This company is located in Lawrence County, South Dakota, providing services to the community in various cities within the county	Government Administration	🇺🇸 Deadwood	550	1877
32	Tyson Fresh Meats, Inc.tysonfreshmeats.com A food production company located in South Dakota, specializing in fresh meats	Food and Beverage Manufacturing	🇺🇸 Dakota Dunes	538	n/a
33	LifeScape lifescapesd.org A company dedicated to empowering individuals to live their best life through innovative services, technology solutions, and collaborative partnerships, guided by integrity and compassion	Hospitals and Health Care	🇺🇸 Sioux Falls	526	1952
34	Billion Automotive billionauto.com A family-owned automotive business with 26 locations, offering career opportunities and comprehensive benefits to employees in multiple states	Motor Vehicle Manufacturing	🇺🇸 Sioux Falls	509	1935
35	BCBG Maxazria An entertainment company located in Sioux Falls, South Dakota, offering a range of services or products	Entertainment Providers	🇺🇸 Sioux Falls	501	n/a
36	My Place Hotels of America myplacehotels.com A team with 40 years of hotel experience created a concept for affordable, modern, clean, and comfortable short to long-term stays	Hospitality	🇺🇸 Aberdeen	479	n/a
37	Microstocksolutions microstocksolutions.com A digital asset content management company providing editing, keywording, metadata, video post-production, curation, legal review, brand consistency, and machine learning services efficiently	Technology, Information and Media	🇺🇸 Sioux Falls	469	2008
38	Midland National Life Insurance Company midlandnational.com Midland National Life Insurance provides life insurance and annuities to protect families, preserve legacies, and make long-term financial decisions with a focus on sustainability	Insurance	🇺🇸 Sioux Falls	464	1906
39	Remax Professionals inc.expireddomains.com Experienced real estate agency in Sioux Falls since 1985, known for top agents and high recognition Specializing in selling properties	Real Estate	🇺🇸 Sioux Falls	456	1985
40	Terex Utilities terex.com Global manufacturer of aerial devices and digger derricks for the electric utility industry, offering innovative solutions, quality service, and support across North America	Machinery Manufacturing	🇺🇸 Watertown	439	n/a
41	Furniture Mart USA furnituremartusa.com Family-owned furniture retail operation with multiple store locations in upper Midwest offering high-quality furniture, mattresses, and accessories with exceptional customer service	Furniture and Home Furnishings Manufacturing	🇺🇸 Sioux Falls	435	1976
42	Dacotah Bank dacotahbank.com A state-chartered bank providing banking, insurance, mortgage, and trust services to customers in the Midwest region, with over $2 billion in assets	Banking	🇺🇸 Aberdeen	426	1963
43	Sterling sterling.com Providing transformative technology solutions including digital workspace, infrastructure, connectivity, security, cloud, and services for diverse public and private sectors.	IT Services and IT Consulting	🇺🇸 North Sioux City	421	1996
44	South Dakota Army National Guard nationalguard.com The South Dakota Army National Guard Recruiting and Retention Battalion offers part-time opportunities for individuals to serve, learn skills, and earn benefits	Armed Forces	🇺🇸 Rapid City	409	1862
45	Vantage Point Solutions vantagepnt.com Vantage Point helps broadband providers with engineering, consulting, and OSP services, securing funding, network design, implementation, cybersecurity, compliance, and more	Engineering Services	🇺🇸 Mitchell	396	2002
46	Five Star Solutions getfivestar.com A customer contact center outsourcer delivering exceptional experiences through passionate, authentic, and happy interactions, with solutions tailored to individual needs	Outsourcing and Offshoring Consulting	🇺🇸 Sioux Falls	396	1986
47	Southeast Tech southeasttech.edu Career-focused technical college offering over 70 programs, certificates, and apprenticeships with passionate faculty, utilizing Sioux Falls as an extended classroom for professional success in two years or less	Higher Education	🇺🇸 Sioux Falls	382	1968
48	Horizon Health horizonhealthcare.org Provider of personalized, affordable, and high-quality medical, dental, and mental health care in rural South Dakota through a network of community-based health centers	Hospitals and Health Care	🇺🇸 Howard	374	1978
49	University of Sioux Falls usiouxfalls.edu A Christian university offering education in liberal arts, sciences, and professions, focusing on academic excellence and developing mature Christian leaders for service	Higher Education	🇺🇸 Sioux Falls	370	1883
50	Rosenbauer America rosenbauer.com The company is a top manufacturer of firefighting vehicles and equipment, combining global innovation with American manufacturing expertise	Motor Vehicle Manufacturing	🇺🇸 Lyons	365	1866
51	OTA weareota.com The company offers creative and collaborative initiatives to empower community-builders and change agents in South Dakota, North Dakota, and Minnesota	Civic and Social Organizations	🇺🇸 Sioux Falls	333	2009
52	Avera St. Luke's Hospital avera.org Regional medical center in Aberdeen, SD, offering comprehensive medical services, long-term care, clinics, specialized services, state-of-the-art technology, and mobile outreach programs	Hospitals and Health Care	🇺🇸 Aberdeen	314	n/a
53	C & B Material Handling burwellmh.com A family-owned company with multiple John Deere dealership locations and expanding into Material Handling and Powersports divisions while upholding core values	Machinery Manufacturing	🇺🇸 Sioux Falls	311	1988
54	Agtegra Cooperative agtegra.com Agricultural cooperative based in South Dakota, owned by farmers and ranchers, offering products and services to support customers and communities	Farming	🇺🇸 Aberdeen	306	2018
55	Mount Marty University mountmarty.edu Private Catholic university focusing on holistic development of individuals through liberal arts education emphasizing intellectual, professional, and personal skills, moral, spiritual, and social values	Higher Education	🇺🇸 Yankton	267	1936
56	CorTrust Bank cortrustbank.com A trusted financial institution with 85 years of experience offering modern banking technology, mortgages, wealth management, insurance, and personalized service	Banking	🇺🇸 Mitchell	265	1930
57	dietplus dietplus.fr A leader in weight loss coaching, offering personalized support, exclusive supplements, and a focus on long-term results in a welcoming and supportive environment	Wellness and Fitness Services	🇺🇸 Behren les Forbach	241	2011
58	MetaBank pathward.com A financial services company focusing on economic mobility and social responsibility, aiming to provide access to financial opportunities for all	Financial Services	🇺🇸 Sioux Falls	236	1954
59	The First National Bank in Sioux Falls fnbsf.com A community-focused bank offering financial services including accounts, loans, and wealth management, with a commitment to simplifying money matters through a podcast	Financial Services	🇺🇸 Sioux Falls	233	1885
60	Big Stone Therapies, Inc.bigstonetherapies.com A company dedicated to providing excellent rehabilitation services to individuals and businesses in communities through hands-on healing	Wellness and Fitness Services	🇺🇸 Big Stone City	232	1990
61	Riverside Technologies, Inc. (RTI)1rti.com IT service provider with 25+ years of experience, offering managed services, IT hardware, warehouse services, and technology deployment for diverse clients nationwide	IT Services and IT Consulting	🇺🇸 North Sioux City	231	1998
62	Adams Thermal Systems adamsthermalsystems.com Global company specializing in designing and manufacturing cooling systems for vehicles and equipment in industries such as agriculture, construction, mining, and more	Industrial Machinery Manufacturing	🇺🇸 Canton	225	2004
63	St. Joseph's Indian School stjo.org Nonprofit organization supporting Native American youth through education, housing, counseling, cultural, and spiritual programming in South Dakota	Non-profit Organizations	🇺🇸 Chamberlain	209	1927
64	First Dakota National Bank firstdakota.com Providing personal, business, agriculture, and wealth & trust services with a hometown touch and unparalleled customer service, focused on fulfilling your financial dreams	Banking	🇺🇸 Yankton	208	1872
65	Carsforsale.com carsforsale.com A leader in the online automotive industry, offering innovative software solutions and a powerful inventory system for dealers and a simplified car-shopping experience for buyers	Technology, Information and Internet	🇺🇸 Sioux Falls	205	1999
66	CNOS cnos.net A multi-specialty organization committed to improving health by providing collaborative clinical expertise and exceeding expectations through quality care and customer service	Hospitals and Health Care	🇺🇸 Dakota Dunes	202	1999
67	Aerostar (Aerostar International LLC)aerostar.com An Aerospace & Defense provider offering stratospheric platforms, radar sensors, technical services, and protective wear for successful operations and saving lives	Defense and Space Manufacturing	🇺🇸 Sioux Falls	195	n/a
68	Vertical Cold Storage verticalcold.com Vertical Cold Storage offers top-notch temperature controlled storage, blast freezing, export services, and exceptional customer service through state-of-the-art facilities and industry expertise	Transportation, Logistics, Supply Chain and Storage	🇺🇸 Dakota Dunes	186	2020
69	BankWest - South Dakota bankwest-sd.bank A local bank in South Dakota with 130 years of history, focusing on customer relationships and community success through personalized banking services	Financial Services	🇺🇸 Pierre	182	1889
70	Dakota Provisions dakotaprovisions.com A company focused on supporting family farms, Dakota Provisions delivers high quality protein products to food service establishments and online retailers	Food and Beverage Services	🇺🇸 Huron	181	2013
71	Sioux Falls Specialty Hospital sfsh.com A physician-owned hospital offering innovative world-class surgery, recovery, imaging, pain management, and primary care with a focus on quality, safety, and patient comfort	Hospitals and Health Care	🇺🇸 Sioux Falls	180	1985
72	Sioux Steel Company siouxsteel.com Manufacturer of high-quality steel products, with a focus on longevity and customer value, offering industry-leading warranties and exceptional service worldwide	Farming	🇺🇸 Sioux Falls	180	1918
73	A&B Business Solutions abbusiness.com Facilitator for businesses providing services, products, and equipment to enhance efficiency and reliability, with 15 locations across five states	Printing Services	🇺🇸 Sioux Falls	180	1981
74	1st Financial Bank USA 1fbusa.com Specializing in credit card and financial services for college students and graduates, offering online banking, construction lending, and community banking in South Dakota	Financial Services	🇺🇸 Dakota Dunes	177	1910
75	Rapid City Medical Center, LLP rapidcitymedicalcenter.com A longstanding independent medical practice in Rapid City, South Dakota, offering a wide range of medical services with a commitment to excellence in healthcare	Hospitals and Health Care	🇺🇸 Rapid City	176	1948
76	ALARIS Group Inc. is now Paradigm paradigmcorp.com An accountable specialty care management organization focused on improving the lives of people with complex and catastrophic injuries through value-based care solutions	Hospitals and Health Care	🇺🇸 Sioux Falls	175	1991
77	Wireless World wirelessworld.com Independently owned Verizon Authorized Retailer with locations in Iowa, South Dakota, Minnesota, Nebraska, and Wisconsin Offers top-rated service, upgrades, and bundle options	Wireless Services	🇺🇸 Sioux Falls	174	2001
78	Innovative Systems innovsys.com A provider of enterprise software solutions to manage business operations, deliver network services, and reduce operating costs for various industries	Telecommunications	🇺🇸 Mitchell	171	1998
79	My3Tech my3tech.com A leading provider of advanced IT solutions globally, offering staff augmentation, software development, cloud, cybersecurity, and technology solutions for business empowerment and innovation	IT Services and IT Consulting	🇺🇸 Pierre	167	2010
80	Falcon Plastics falconplastics.com A leading custom injection molding company founded in 1975, specializing in direct product design from start to finish, with additional expertise in blow molding	Plastics Manufacturing	🇺🇸 Brookings	167	1975
81	Lunchtime Solutions, Inc.lunchtimesolutions.com School food service management company providing healthy menu choices for students in multiple states, while allowing districts to maintain control over their programs	Food and Beverage Services	🇺🇸 North Sioux City	166	1997
82	SDN Communications sdncommunications.com Premier provider of business broadband services in the region, offering extensive fiber-optic network for voice, data, internet, and video services to businesses	Telecommunications	🇺🇸 Sioux Falls	166	1989
83	Profile Plan hmrprogram.com A physician and scientist-designed weight management program, Profile Plan offers a simple, effective, and sustainable solution with certified coaches	Wellness and Fitness Services	🇺🇸 Sioux Falls	164	2012
84	Todd County School District tcsdk12.org An education management company in Mission, South Dakota, providing educational services and support to the Todd County School District	Education Administration Programs	🇺🇸 Mission	163	n/a
85	Building Products Inc.bpi.build A building materials distributor with offices in multiple states, focused on developing partnerships, fulfilling commitments, and upholding integrity	Wholesale	🇺🇸 Sioux Falls	161	1957
86	Mitchell Technical College mitchelltech.edu Mitchell Tech offers affordable, hands-on education in high-demand fields, with programs developed in response to industry needs for career-ready graduates	Higher Education	🇺🇸 Mitchell	160	n/a
87	Shurco shurco.com The company is the leading manufacturer of tarp and containment systems in North America with multiple manufacturing and service centers	Truck Transportation	🇺🇸 Yankton	157	1954
88	Dakota Bodies dakotabodies.com A leading manufacturer of utility and service truck bodies with a strong focus on growth, innovation, and customer satisfaction through new technologies and techniques	Motor Vehicle Manufacturing	🇺🇸 Watertown	156	1997
89	Get n Go getngo.com A leading convenience store chain with 19 locations, focused on growth, development of team members, and customer care for over 60 years	Retail	🇺🇸 Sioux Falls	155	n/a
90	RENEW takkion.com Premier service provider offering logistics, O&M, technical repair, and remanufacturing services to the renewable energy industry in North America	Services for Renewable Energy	🇺🇸 Sioux Falls	155	2009
91	South Dakota Department of Transportation dot.sd.gov Providing a safe and efficient public transportation system to enhance lives through improved transportation services	Truck Transportation	🇺🇸 Pierre	155	1917
92	Wapiti Medical Staffing wapitimedical.com Medical staffing agency providing locum providers for Clinic, ER, Hospitalist, Urgent Care, and Anesthesia placements nationwide with top-notch support and accolades	Staffing and Recruiting	🇺🇸 Milbank	153	1999
93	Pennington County Sheriff's Office pennco.org The Pennington County Sheriff’s Office provides law enforcement, addiction services, and juvenile services to the community with a staff of over 440 employees	Public Safety	🇺🇸 Rapid City	152	n/a
94	Great Plains Tribal Health greatplainstribalhealth.org The company advocates for access to high-quality health resources through research, education, prevention, and outreach for tribal leaders in Great Plains	Public Health	🇺🇸 Rapid City	152	1986
95	OPHTHALMOLOGY ASSOCIATES aberdeeneyes.com A medical practice specializing in ophthalmology, located in Aberdeen, SD, offering services related to eye care and vision health	Medical Practices	🇺🇸 Aberdeen	152	n/a
96	Black Hills Surgical Hospital bhsh.com Specialized surgical hospital offering orthopedic, spine, imaging, pain management, sports medicine, occupational medicine, and urgent care services with compassionate, expert physicians.	Hospitals and Health Care	🇺🇸 Rapid City	151	1997
97	California Intercontinental University caluniversity.edu Online university promoting quality learning and critical thinking to help students excel in their career goals and become successful business leaders	Higher Education	🇺🇸 Sioux Falls	150	1996
98	Sanford Health Plan sanfordhealthplan.com Provider-owned health plan offering affordable coverage in the upper Midwest with a network of expert providers and innovative care coordination NCQA accredited	Insurance	🇺🇸 Sioux Falls	150	1997
99	South Dakota Department of Health doh.sd.gov Health department in South Dakota dedicated to promoting the health and well-being of residents by providing current health information and resources	Government Administration	🇺🇸 Pierre	149	n/a
100	Black Hills Information Security blackhillsinfosec.com Specializes in penetration testing, red teaming, threat hunting, Active SOC services, educational webinars, workshops, and training. Creates incident response card game.	Computer and Network Security	🇺🇸 Spearfish	147	2008

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Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Oct 24, 2026.

The same list elsewhere in United States

The largest companies in the United States 91,669
The largest companies in California 12,813
The largest companies in New York State 10,485
The largest companies in Texas 8,086
The largest companies in Florida 4,945
The largest companies in Illinois 4,175
The largest companies in Pennsylvania 3,110
The largest companies in Massachusetts 3,093
The largest companies in Georgia 2,632
The largest companies in Ohio 2,618
The largest companies in New Jersey 2,569
The largest companies in Virginia 2,503
The largest companies in Michigan 2,346
The largest companies in North Carolina 2,174
The largest companies in Alabama 1,806
The largest companies in Washington State 1,785
The largest companies in Colorado 1,774
The largest companies in Minnesota 1,700
The largest companies in Maryland 1,527
The largest companies in Wisconsin 1,482
The largest companies in New York 6,920
The largest companies in San Francisco 2,030
The largest companies in Houston 1,791
The largest companies in Chicago 1,668