| # | Company | Employees |
|---|---|---|
| 1 |
Enterprise Mobilityenterprisemobility.com
Provides comprehensive mobility solutions worldwide, focusing on innovative, accessible, efficient, and sustainable transportation for people and goods. |
70,005 |
| 2 |
Ascensionhealthcare.ascension.org
A faith-based healthcare organization focused on providing compassionate care to those in need across the US through various services and programs |
66,381 |
| 3 |
Emersonemerson.com
A global technology and engineering company providing innovative solutions for industrial and commercial markets, driving innovation for a healthier, safer, and smarter world |
51,841 |
| 4 |
Edward Jonesedwardjones.com
Provides personalized financial advisory and investment services through a large network of advisors to help clients achieve financial goals. |
45,845 |
| 5 |
Centene Corporationcentene.com
Providing affordable, high-quality healthcare plans for Medicaid, Medicare, and marketplace members, focusing on under-insured and uninsured individuals nationwide. |
36,022 |
| 6 |
Enterpriseenterprisemobility.com
Provides car rental services globally through multiple brands, offering employment opportunities and vehicle access in many countries. |
32,638 |
| 7 |
BJC Healthbjc.org
One of the largest nonprofit health care organizations in the US, focused on providing a wide range of healthcare services in St Louis and southern Illinois regions |
29,641 |
| 8 |
Advantage Solutionsyouradv.com
Provider of outsourced sales and marketing services including retail merchandising, digital commerce, sampling, and omnichannel marketing for consumer goods companies. |
27,762 |
| 9 |
SSM Healthssmhealth.com
Not-for-profit healthcare system providing hospitals, physician offices, outpatient, virtual care, home care, hospice, pharmacy, insurance, and accountable care services. |
19,955 |
| 10 |
Washington University in St. Louiswashu.edu
Private university focusing on teaching, research, and fostering knowledge creation while engaging with a diverse, multicultural community. |
18,070 |
| 11 |
Wells Fargo Advisorswellsfargoadvisors.com
Financial advisors providing professional investment guidance and wealth management services across fifty states to help clients achieve long-term success through complex planning. |
14,935 |
| 12 |
Express Scripts Pharmacy Benefit Servicesevernorth.com
Creation and management of prescription benefit programs aimed at reducing costs for members, health plans, employers, and agencies. |
12,361 |
| 13 |
Caleres, Inc.jobs.caleres.com
This company is a global footwear brand portfolio with diverse offerings, including famous labels like Sam Edelman and Naturalizer, focusing on consumer-driven innovation and quality craftsmanship |
9,313 |
| 14 |
Monsanto Companybayer.com
Leading in modern agriculture with a focus on seeds, plant traits, and crop protection through innovative breakthroughs for global impact |
9,303 |
| 15 |
Nestlรฉ Purina North Americapurinajobs.com
Advances pet nutrition science, collaborates on innovation, and enriches lives of pets and owners. Builds strong teams for pet care. |
8,321 |
| 16 |
Graybargraybar.com
A Fortune 500 employee-owned corporation distributes electrical, communications, and networking products, offering supply chain management and logistics services to customers |
8,118 |
| 17 |
Saint Louis Universityslu.edu
A Jesuit, Catholic university in St Louis, MO offering top research programs Oldest university in the West, with a campus in Madrid, Spain |
7,855 |
| 18 |
Washington University School of Medicine in St. Louismedicine.washu.edu
A prestigious medical school renowned for patient care, research, and education, offering top-ranked programs in medicine, science, and healthcare fields |
7,517 |
| 19 |
Stifel Financial Corp.stifel.com
Providing brokerage, trading, investment banking, advisory, and trust services to individuals, businesses, and municipalities across the U.S. |
7,384 |
| 20 |
Evernorth Health Servicesevernorth.com
Provider of adaptable pharmacy, care, and benefit services aiming to advance organizations and individuals through connected solutions |
7,188 |
| 21 |
Anheuser-Buschanheuser-busch.com
A leading brewer in the United States with a legacy of crafting high-quality beers, supporting communities, and valuing talented employees |
7,091 |
| 22 |
Amerenameren.com
A Fortune 500 company based in St Louis, providing electric and natural gas services to millions of customers in Illinois and Missouri |
7,078 |
| 23 |
Barnes-Jewish Hospitalbarnesjewish.org
Flagship hospital of BJC HealthCare offering advanced cancer treatment through the only National Cancer Institute-designated Comprehensive Cancer Center in Missouri. |
6,733 |
| 24 |
McCarthy Building Companies, Inc.mccarthy.com
A long-standing American construction company specializing in building essential projects nationwide, with a commitment to quality, safety, diversity, and equitable pay practices |
6,263 |
| 25 |
Energizer Holdingsenergizerholdings.com
A global organization creating innovative products to improve lives, focused on serving customers, driving revenue, and delivering long-term value |
6,098 |
| 26 |
Varsity Tutors, a Nerdy Companyvarsitytutors.com
A leading online learning platform leveraging technology to connect learners with experts across a wide range of subjects and formats |
5,970 |
| 27 |
Wellcare Medicarewellcare.com
A company based in Tampa providing government-sponsored managed care services to families, children, seniors, and individuals with complex medical needs nationwide |
5,306 |
| 28 |
Copelandcopeland.com
Develop sustainable HVACR technologies for residential, commercial, and industrial spaces, ensuring cold chain integrity and global comfort. |
4,804 |
| 29 |
Barry-Wehmillerbarrywehmiller.com
The company is dedicated to improving the lives of its global team through meaningful work, care, compassion, and personal growth initiatives |
4,395 |
| 30 |
Emerson Commercial & Residential Solutions
A company formerly known as Emerson Commercial and Residential Solutions now operates as Copeland, specializing in commercial and residential solutions |
4,189 |
| 31 |
Belden Inc.belden.com
Connecting information and intelligence to simplify, secure, and enhance the digital journey for customers transforming the way the world works |
4,091 |
| 32 |
Accredo Specialty Pharmacyaccredo.com
specialty pharmacy providing personalized care and medication management for patients with chronic, complex, and rare conditions through expert clinical teams |
3,599 |
| 33 |
Build-A-Bear Workshopbuildabear.com
A beloved brand offering unique retail and entertainment experiences through customizable furry friend creations in over 400 worldwide locations |
3,522 |
| 34 |
Sigma-Aldrichbit.ly
Providing scientists with lab materials, technologies, and services to simplify, accelerate, and improve life science research and biotech production worldwide. |
3,467 |
| 35 |
Enterprise Fleet Managementefleets.com
A family-owned enterprise managing nearly a million vehicles in the US and Canada, offering fleet management services for businesses and organizations |
3,409 |
| 36 |
Maritzmaritz.com
A behavioral science-driven company solving business challenges for Fortune 500 clients through research, incentives, rewards, experience design, and events services and solutions |
3,349 |
| 37 |
Webster Universitywebster.edu
A global network of faculty, staff, students, and alumni focused on high-quality learning experiences for global citizenship and individual excellence |
3,249 |
| 38 |
University of Missouri-Saint Louisumsl.edu
A public research university offering diverse learning experiences, leadership opportunities, and high-ranking programs to a large student body in St Louis |
3,152 |
| 39 |
Whelan Securitygarda.com
Industry-leading contract security company in the US, providing quality services to diverse clients and seeking talented individuals for security officer positions |
3,133 |
| 40 |
Peabody Energypeabodyenergy.com
Leading coal producer supplying essential materials for affordable energy generation and steel manufacturing with a strong focus on sustainability. |
3,106 |
| 41 |
Watlowwatlow.com
Global industrial technology company, expertise in thermal systems, providing temperature control, power control, heater technologies, and temperature sensing platforms to various industries. |
2,840 |
| 42 |
Saint Louis Public Schoolsslps.org
Providing quality education to students in the St Louis region, aiming to become a national leader in student achievement and teacher quality |
2,721 |
| 43 |
Drury Hotelsjobs.druryhotels.com
Drury Hotels offers a supportive family-like environment with a focus on exceptional customer service, employee well-being, and growth opportunities in the hospitality industry |
2,664 |
| 44 |
St. Louis Children's Hospitalstlouischildrens.org
A leading pediatric teaching hospital offering comprehensive medical care, education, and injury-prevention programs with a team dedicated to children's well-being |
2,635 |
| 45 |
St. Louis Countystlouiscountymo.gov
A diverse and populous county in Missouri known for its economic vitality, parks, education system, and local government services |
2,482 |
| 46 |
Core & Maincoreandmain.com
Leading specialized distributor focused on water, wastewater, storm drainage, and fire protection products nationwide, providing solutions to municipalities, water companies, and contractors |
2,479 |
| 47 |
Hair Saloonยฎhairsaloon.com
Premium hair cutting franchise offering comfort, convenience, and perfect haircuts for men inspired by reinventing the traditional neighborhood barbershop with an Honorable Rebellion Among Menยฎ |
2,476 |
| 48 |
Suddenlink Communicationsoptimum.com
The company is a leading cable operator in the US, providing information, communication, and entertainment services to residential and commercial customers in multiple states |
2,260 |
| 49 |
City of St. Louisstlouis-mo.gov
Provides municipal governance, public services, and community support for residents and businesses in St. Louis, Missouri. |
2,253 |
| 50 |
FleishmanHillardfleishmanhillard.com
Global communications agency specializing in inclusive culture, diversity initiatives, award-winning public relations, and community service across multiple countries. |
2,252 |
| 51 |
Bunzl Distribution NAbunzldistribution.com
A leading distributor of food packaging, disposable supplies, cleaning products, and safety items to a variety of businesses across North America |
1,974 |
| 52 | 1,887 | |
| 53 |
EmpowerMe Wellnessempowerme.com
A healthcare provider in senior living, offering on-site therapy and pharmacy services nationwide, focused on improving the lives of seniors |
1,696 |
| 54 |
BW Design Groupbwdesigngroup.com
This company is a fully integrated engineering, architecture, construction, and consulting firm serving leading companies with customized solutions |
1,676 |
| 55 |
Maryville University of Saint Louismaryville.edu
Private university offering over 90 undergraduate, master's, and doctoral programs, serving diverse students nationwide and internationally with strong athletics. |
1,674 |
| 56 |
SSM Health Saint Louis University Hospitalssmhealth.com
An academic medical center affiliated with Saint Louis University School of Medicine, offering cutting-edge treatments, research, and compassionate care to patients |
1,563 |
| 57 |
Coldwell Banker Realty - Gundakercbgundaker.com
Residential real estate brokerage in St Louis with 15 offices and over 1,400 independent sales associates serving metropolitan St Louis and east-central Missouri |
1,549 |
| 58 |
Tim Hortons STLww16.timhortonstl.com
Company specializing in premium Arabica coffee, baked goods, sandwiches, and other food items Opening Tim Hortons locations throughout St Louis |
1,542 |
| 59 |
St. Anthony's Medical Centermercy.net
A leading medical center providing advanced medical treatment in various specialties and services to communities in Missouri and Illinois Staffed by skilled professionals |
1,542 |
| 60 |
Missouri Baptist Medical Centermissouribaptist.org
A member of BJC HealthCare, providing world-class medical treatments, innovative technology, and career development opportunities in a compassionate environment |
1,486 |
| 61 |
EyeCare Partnerseyecare-partners.com
EyeCare Partners is dedicated to reinventing eye care by uniting optometry and ophthalmology practices to provide high-quality, accessible, and personalized vision health solutions nationwide |
1,457 |
| 62 |
Federal Reserve Bank of St. Louisstlouisfed.org
The company serves as a central bank of the United States, conducting monetary policy, regulating banks, providing payment services, and promoting community development and financial education |
1,431 |
| 63 |
Vegetables by Bayervegetables.bayer.com
A St Louis-based food production company specializing in vegetable seeds, part of Bayer CropScience |
1,354 |
| 64 |
SSM Health St. Louisssmhealth.com
A Catholic, not-for-profit health system known for using quality measures to improve care, with hospitals and facilities in the St Louis region |
1,314 |
| 65 |
National Car Rentalnationalcar.com
Premium car rental service specializing in airport rentals, offering fast vehicle selection, loyalty programs, and exclusive member benefits worldwide. |
1,293 |
| 66 |
BJC HealthCarebjc.org
Nonprofit healthcare organization providing integrated hospital services, focusing on community health, innovation, education, and exceptional patient care across Missouri and Illinois. |
1,279 |
| 67 |
Colibri Groupcolibrigroup.com
This company provides professional education solutions for licensing, continuing education, test preparation, and career readiness, helping individuals excel in their careers |
1,276 |
| 68 |
Hogan Transportation Companieshogan1.com
A nationwide team dedicated to providing exceptional customer service and expanding service facilities, offering great career opportunities and a strong company culture |
1,270 |
| 69 |
Ansiraansira.com
It provides marketing technology and services, helping companies connect with customers through integrated digital and physical experiences to enhance brand loyalty. |
1,266 |
| 70 |
Ascension Technologiesascension.org
A healthcare IT services organization leveraging technology for collaborative solutions, enhancing user experience, and strengthening cybersecurity to support community health |
1,233 |
| 71 |
Post Holdingspostholdings.com
A consumer packaged goods holding company specializing in ready-to-eat cereal, refrigerated foods, foodservice, pet food, and private brand food categories |
1,144 |
| 72 |
Arch Resources, Inccorenaturalresources.com
Producer and exporter of metallurgical and thermal coals, operating multiple mines and marine export terminals focused on seaborne markets. |
1,136 |
| 73 |
Safety Nationalsafetynational.com
A leading specialty insurance and reinsurance provider with over 80 years of experience, offering expertise, flexible programs, unique claims proficiency, and top workplace awards |
1,108 |
| 74 |
ArchKey Solutionsarchkey.com
A leading specialty trade installation and facilities services company with expertise in electrical, technologies, and specialty systems for new and existing facilities |
1,100 |
| 75 |
Baldwin Technologybwconverting.com
A global provider of innovative process-automation equipment, parts, service, and consumables for printing, packaging, textile, plastics, and corrugated industries |
1,080 |
| 76 |
RubinBrown LLPrubinbrown.com
Offering unmatched service to various sectors, we provide expert accounting and consulting services to help clients build and protect value |
1,057 |
| 77 |
Carbolinecarboline.com
A global leader in high-performance coatings, linings, and fireproofing products, offering innovative solutions tailored to customer needs with proven reliability |
1,048 |
| 78 |
Thompson Coburn LLPthompsoncoburn.com
Full-service law firm with offices nationwide, serving Fortune 500 to emerging companies across various industries with industry-specific expertise and exceptional client service |
1,030 |
| 79 |
Focus Financial Partnersfocusfinancialpartners.com
Leading partnership of independent wealth management firms providing best practices, resources, and continuity planning to serve individuals, families, employers, and institutions |
1,028 |
| 80 |
TricorBrauntricorbraun.com
A global packaging purchaser providing cost-effective solutions across industries, offering custom and stock packaging options while prioritizing customer satisfaction and expertise |
1,013 |
| 81 | 1,010 | |
| 82 |
Alberici Constructorsalberici.com
Diversified construction company delivering complex projects across North America with quality, integrity, and a focus on employee expertise and client satisfaction. |
1,002 |
| 83 |
Nestlรฉ Purina Latin America & Caribbeannestle.com
This company focuses on enhancing the lives of pets and their owners through nutritious food sourced responsibly, with a portfolio of recognized brands |
999 |
| 84 |
Bryan Cavebryancave.com
Global law firm with 1,600 lawyers in 32 offices offering clients integrated legal advice, specializing in M&A, real estate, financial services, litigation, and corporate risk practices |
984 |
| 85 |
Enterprise Truck Rentalenterprisetrucks.com
A leading truck rental service offering a wide range of vehicles for business and personal use, with competitive rates and exceptional customer service |
974 |
| 86 |
Envisionenvision.com
Envision, LLC helps professionals find rewarding IT careers in Consumer Packaged Goods and Retail markets with top salaries and benefits |
924 |
| 87 |
WellsFargo.com
Ralph Adams specializes in providing high-quality professional services and solutions tailored to meet the unique needs of its clients |
920 |
| 88 |
TierPointtierpoint.com
The company specializes in simplifying modern IT infrastructure, empowering businesses to innovate, surpass customer expectations, and increase revenue |
909 |
| 89 |
Aclaraaclara.com
A leading supplier of smart infrastructure solutions for water, gas, and electric utilities worldwide, offering devices, software, and services for efficient operations and customer engagement |
893 |
| 90 |
MERS / Goodwillmersgoodwill.org
The organization aims to create opportunities for individuals facing barriers to employment, helping them work and live more independently in the community |
887 |
| 91 |
Cass Information Systemscassinfo.com
Provider of integrated information and payment management solutions for supply chains, communications, facilities, and operations, disbursing over $90 billion annually |
870 |
| 92 |
Bi-State Developmentbistatedev.org
A dynamic organization focused on economic development, public transit, regional freight logistics, and infrastructure improvements in the St Louis region since 1949 |
852 |
| 93 |
Mehlville School Districtmehlvilleschooldistrict.com
The Mehlville School District in St Louis County provides educational services to approximately 10,300 students in a community of over 90,000 residents |
849 |
| 94 |
Cedarhurst Senior Livingcedarhurstliving.com
Experienced operator of senior living communities offering Independent Living, Assisted Living, Personal Care, and Memory Care services across multiple states Mission to create supportive communities |
842 |
| 95 |
Archdiocese of St. Louisarchstl.org
An organization in the Archdiocese of St Louis dedicated to living and spreading the teachings of Jesus Christ through prayer, worship, service, and unity |
839 |
| 96 |
4M Building Solutions4-m.com
A leading commercial cleaning partner with over 45 years of experience, delivering customized solutions and professional cleaning services to property and facility managers |
837 |
| 97 |
BJC Medical Groupbjc.org
A healthcare group with over 600 doctors providing personalized care in St Louis, mid-Missouri, and southern Illinois, backed by top resources and recognized as a top workplace |
836 |
| 98 |
Equifax Workforce Solutionsworkforce.equifax.com
This company provides data, technology, and insights to help organizations make critical HR decisions with greater confidence, ensuring compliance and workforce management |
830 |
| 99 |
SSM Health Cardinal Glennon Children's Hospitalssmhealth.com
A non-profit Catholic pediatric hospital providing high-quality care to children with complex conditions, located in St Louis, MO |
824 |
| 100 |
The Climate Corporationclimate.com
Helps global agriculture industry optimize decision-making, return on investment, and farm inputs with detailed imagery and data layers, weather modeling, and agronomic modeling. |
820 |
Turn this list into pipeline
Tamtam finds the decision-makers at every company on a list like this one, with verified emails, phone numbers and the buying signals that tell you when to reach out.
How this list is built
Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Oct 9, 2026.
More company lists in St. Louis
- Hospitals and Health Care companies in St. Louis 41
- IT Services and IT Consulting companies in St. Louis 27
The same list elsewhere in United States
- The largest companies in the United States 91,636
- The largest companies in New York 6,921
- The largest companies in San Francisco 2,031
- The largest companies in Houston 1,790
- The largest companies in Chicago 1,669
- The largest companies in Los Angeles 1,245
- The largest companies in Atlanta 1,146
- The largest companies in Washington 1,082
- The largest companies in Austin 1,076
- The largest companies in Dallas 1,036
- The largest companies in Boston 988
- The largest companies in Miami 879
- The largest companies in San Diego 677
- The largest companies in Denver 645
- The largest companies in Seattle 593
- The largest companies in Philadelphia 504
- The largest companies in Charlotte 501
- The largest companies in San Jose 479
- The largest companies in Phoenix 473
- The largest companies in Indianapolis 455
- The largest companies in Portland 429
- The largest companies in Minneapolis 424
- The largest companies in Tampa 421
- The largest companies in Columbus 418