| # | Company | Employees |
|---|---|---|
| 1 |
Hy-Vee, Inc.hy-vee.com
Operate over 563 supermarkets across nine Midwestern states, focusing on quality, variety, convenience, healthy lifestyles, and excellent customer service. |
93,000 |
| 2 |
UnityPoint Healthunitypoint.org
Not-for-profit health system providing hospital, clinic, and home health services across Iowa, Illinois, and Wisconsin with patient-centered care. |
10,341 |
| 3 |
Farm Bureau Financial Servicesfbfs.com
Providing insurance products and financial planning services including auto, home, life, farm, business insurance, wealth management, and advisory services. |
2,583 |
| 4 |
Atheneathene.com
Provides retirement income and savings products, fixed annuities, reinsurance, and institutional pension solutions across multiple countries. |
2,049 |
| 5 |
Sammons Financial Group Companiessammonsfinancialgroup.com
A privately held financial group providing life insurance, annuities, and retirement products with a values-based culture and commitment to communities |
1,603 |
| 6 |
National Speech & Debate Association (NSDA)speechanddebate.org
National society fostering student growth through speech and debate, cultivating communication skills, critical thinking, and ethical engagement in democracy |
1,549 |
| 7 |
Wright Tree Servicewrighttree.com
An employee-owned company providing vegetation management services including utility line clearance, land clearing, and response to natural disasters for power restoration |
1,273 |
| 8 |
Des Moines University Medicine and Health Sciencesdmu.edu
A graduate medicine and health sciences university in West Des Moines, Iowa, founded in 1898 |
993 |
| 9 |
Iowa Realtyiowarealty.com
Iowa's largest real estate brokerage based in Des Moines, with offices throughout the state Providing services for residential and commercial real estate buyers and sellers |
923 |
| 10 |
ITA Group, Inc.itagroup.com
It helps brands enhance sales and retention through events, incentives, and recognition, fostering connections and motivating employees and customers. |
922 |
| 11 |
Care Initiativescareinitiatives.org
Iowa's largest not-for-profit provider offering transitional health care services including skilled nursing, rehabilitation, long term care, and hospice care |
819 |
| 12 |
West Des Moines Community Schoolswdmcs.org
The school district offers a wide range of academic programs, personalized learning experiences, and opportunities for students to connect with their community Graduates are prepared for a diverse world |
812 |
| 13 |
The Iowa Cliniciowaclinic.com
A large multi-specialty physician group in Central Iowa offering leading-edge healthcare and exceptional customer service through partnership with local medical centers |
763 |
| 14 |
Telligentelligen.com
With over 45 years of experience, we provide healthcare expertise to improve employee health, contain costs, and advance innovation in healthcare delivery |
686 |
| 15 |
Carrotget-carrot.com
A global fertility and family-building platform offering comprehensive care, cost savings for employers, and award-winning experiences for individuals worldwide |
617 |
| 16 |
SEO Expertseo.expert
A dedicated team of SEO experts who live for data, specializing in white hat techniques to drive organic traffic and increase revenue for clients |
570 |
| 17 |
Owner Revolutionownerrevolution.com
An Iowa-based employee-owned holding company with a subsidiary specializing in manufacturing commercial and industrial ultrasonic cleaning equipment globally |
549 |
| 18 |
GuideOne Insuranceguideone.com
Providing insurance coverage and support to faith-based and social mission organizations, enabling them to focus on their core work. |
507 |
| 19 |
Farmers Mutual Hail Insurancefmh.com
A long-standing provider of crop insurance and risk management solutions for American farmers, offering comprehensive coverage for farms, ranches, and families |
456 |
| 20 |
Accura HealthCareaccurahc.com
Iowa-based healthcare company managing skilled nursing, rehabilitation, and senior housing centers in four states with an upside-down organizational philosophy |
446 |
| 21 |
Liberty Banklibertybankiowa.com
A community bank with a customer-focused approach, offering personalized service and financial security for individuals and businesses |
385 |
| 22 |
Homesteaders Life Companyhomesteaderslife.com
Provides life insurance products and services focused on helping policyholders plan and design a better farewell experience. |
381 |
| 23 |
Aureonaureon.com
Aureon offers reliable business solutions in telecommunications, IT, consulting, and contact center operations, customized to meet client needs Connect for solutions |
380 |
| 24 |
QCI. More Than Technology. Understanding.qci.com
Tech consulting firm founded in 1995 in Iowa, assisting clients in leveraging technology for success by attracting top talent to deliver exceptional results |
326 |
| 25 |
BSB Designbsbdesign.com
A national architecture firm creating regionally sensitive designs, offering land planning, landscape architecture, estimating services, and specializing in various design types |
321 |
| 26 |
Windsor Windows and Doorswindsorwindows.com
A national manufacturer of premium windows and patio doors, offering custom-built products in wood, PVC, and vinyl for residential, commercial, and historical applications |
316 |
| 27 |
West Bankwestbankstrong.com
A full-service bank providing banking and trust services to businesses and consumers in the Midwest, with a strong focus on community involvement |
216 |
| 28 |
Hubbell Realty Companyhubbellrealty.com
A reputable real estate developer and property management firm, providing a full range of real estate services including construction, land development, and property management |
199 |
| 29 |
Iowa Home Careiowahomecare.com
Providing professional and compassionate home health care services, including skilled nursing, therapy, social work, and personal care to help individuals thrive at home |
171 |
| 30 |
R&R Realty Grouprrrealty.com
Leader in commercial real estate in Des Moines, Iowa, offering property management, development, construction, technology, investments, and brokerage services with premier properties in the metro area |
164 |
| 31 |
Wild Rose Casino & Hotel - Clinton, Emmetsburg, Jeffersonwildroseresorts.com
Iowa-based company offering gaming and hotel accommodations in Clinton, Emmetsburg, and Jefferson, with a corporate office in Des Moines |
161 |
| 32 |
BioSpacebiospace.com
digital platform connecting life science professionals and organizations, providing news, insights, and job opportunities to advance global health. |
157 |
| 33 |
Iowa Farm Bureauiowafarmbureau.com
Established in 1918, this organization is dedicated to supporting agriculture, farm families, and communities in Iowa through advocacy and progress |
155 |
| 34 |
Glen Oaks Country Clubglenoakscc.com
Privately owned golf and country club in Iowa offering exceptional experiences for members with golf, dining, social activities, family focus, events, and top-notch service |
153 |
| 35 |
Auzmorauzmor.com
Rethinks software for companies and employees, making it invisible and assistive, enabling HR leaders to focus on employee well-being. |
68 |
| 36 |
Kaufman Constructionkaufmanconstruction.com
Specializing in remodeling, building new homes with character, and restoring older homes, we focus on quality design and construction with excellent customer service |
26 |
| 37 |
Hart Family Hotelshartfamilyhotels.com
A full service hotel management company specializing in high guest satisfaction, top-tier financial management, consultations, short term gap filling, and long-term management contracts |
23 |
| 38 |
Check-All Valve Mfg. Co.checkall.com
Specializing in spring loaded check valves, this company is known for high quality, innovation, and cost efficiency in designing and manufacturing rugged performance valves |
20 |
| 39 |
ManchesterStorymanchesterstory.com
Venture capital firm focused on investing in FinTech and Healthcare companies, with a niche in technologies that impact the insurance industry |
11 |
| 40 |
Granite Financial Solutions, LLCgfsinvest.com
A full-service financial firm offering a wide range of products and services to help individuals and business owners reach their financial goals |
5 |
| 41 |
Clean America Energycleanamericaenergy.com
An emerging company focusing on solar energy solutions and innovations within the industry |
3 |
Turn this list into pipeline
Tamtam finds the decision-makers at every company on a list like this one, with verified emails, phone numbers and the buying signals that tell you when to reach out.
How this list is built
Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Oct 24, 2026.
The same list elsewhere in United States
- The largest companies in the United States 91,669
- The largest companies in California 12,813
- The largest companies in New York State 10,485
- The largest companies in Texas 8,086
- The largest companies in Florida 4,945
- The largest companies in Illinois 4,175
- The largest companies in Pennsylvania 3,110
- The largest companies in Massachusetts 3,093
- The largest companies in Georgia 2,632
- The largest companies in Ohio 2,618
- The largest companies in New Jersey 2,569
- The largest companies in Virginia 2,503
- The largest companies in Michigan 2,346
- The largest companies in North Carolina 2,174
- The largest companies in Alabama 1,806
- The largest companies in Washington State 1,785
- The largest companies in Colorado 1,774
- The largest companies in Minnesota 1,700
- The largest companies in Maryland 1,527
- The largest companies in Wisconsin 1,482
- The largest companies in New York 6,920
- The largest companies in San Francisco 2,030
- The largest companies in Houston 1,791
- The largest companies in Chicago 1,668