# Top 25 medical device companies in Irvine

Tamtam tracks 25 medical device companies headquartered in Irvine. This list ranks all of them by number of employees on LinkedIn, led by Edwards Lifesciences, Toshiba and Masimo. Their median headcount is 378. Half of them were founded in 2003 or later.

The companies listed are predominantly mid-sized to large firms specializing in medical device manufacturing and biotechnology research in Irvine. Most were founded between the 1970s and early 2000s, reflecting a mature industry presence.

Edwards Lifesciences develops structural heart technologies, while Masimo focuses on noninvasive patient monitoring. Glidewell Dental pioneers digital dentistry innovations, and Allergan Aesthetics, an AbbVie Company, markets leading aesthetic products. Toshiba, though primarily in electronics, also has a significant presence here, indicating a broader tech ecosystem.

🇺🇸 Irvine · 25 companies · Updated Nov 12, 2026

| # | Company | Industry | Headquarters | Employees | Founded |
|---|---|---|---|---|---|
| 1 | [Edwards Lifesciences](https://www.tamtam.ai/c/edwards-lifesciences) (edwards.com)<br>Develops breakthrough structural heart technologies and medical devices for patients, partnering with clinicians to improve lives globally across over 100 countries. | Medical Equipment Manufacturing | 🇺🇸 Irvine | 14,148 | 1958 |
| 2 | [Toshiba](https://www.tamtam.ai/c/toshiba) (toshiba.com)<br>A global technology company focusing on energy, infrastructure, electronics, and digital solutions to create a sustainable future for generations to come | Appliances, Electrical, and Electronics Manufacturing | 🇺🇸 Irvine | 8,787 | 1965 |
| 3 | [Masimo](https://www.tamtam.ai/c/masimo) (masimo.com)<br>Develops and manufactures innovative noninvasive patient monitoring technologies and sensors to improve clinical decision-making and patient safety worldwide. | Medical Equipment Manufacturing | 🇺🇸 Irvine | 3,667 | 1989 |
| 4 | [Allergan Aesthetics, an AbbVie Company](https://www.tamtam.ai/c/allergan-aesthetics-an-abbvie-company) (global.allerganaesthetics.com)<br>Develop, manufacture, and market a portfolio of leading aesthetics products including facial injectables, body contouring, plastics, and skin care. | Pharmaceutical Manufacturing | 🇺🇸 Irvine | 2,456 |  |
| 5 | [Glidewell Dental](https://www.tamtam.ai/c/glidewell-dental) (glidewelldental.com)<br>Pioneering digital dentistry innovations, offering comprehensive, cost-effective clinical solutions, combining open digital workflows, AI-powered manufacturing, and vertically integrated operations to empower dental professionals. | Medical Equipment Manufacturing | 🇺🇸 Irvine | 2,238 | 1970 |
| 6 | [Advanced Sterilization Products](https://www.tamtam.ai/c/advanced-sterilization-products) (asp.com)<br>Global leader providing advanced products, technologies, and workflows for medical sterilization and disinfection, dedicated to defending lives of patients and healthcare workers. | Medical Equipment Manufacturing | 🇺🇸 Irvine | 1,532 |  |
| 7 | [Inari Medical](https://www.tamtam.ai/c/inari-medical) (inarimedical.com)<br>Treats venous and other diseases, offers innovative products and services in MedSurg, Neurotechnology, Orthopedics to improve patient and healthcare outcomes. | Medical Equipment Manufacturing | 🇺🇸 Irvine | 688 |  |
| 8 | [Axonics, Inc.](https://www.tamtam.ai/c/axonics-inc) (bostonscientific.com)<br>Develops and sells medical devices to treat bladder and bowel dysfunction, including sacral neuromodulation systems and hydrogels for urinary incontinence. | Medical Equipment Manufacturing | 🇺🇸 Irvine | 618 | 2013 |
| 9 | [Nihon Kohden America](https://www.tamtam.ai/c/nihon-kohden-america) (us.nihonkohden.com)<br>Manufacturer of patient monitoring, sleep assessment, neurology, and cardiology instruments focused on quality, innovation, and healthcare professional needs. | Medical Equipment Manufacturing | 🇺🇸 Irvine | 566 | 1979 |
| 10 | [InMode](https://www.tamtam.ai/c/inmode) (inmodemd.com)<br>Develops, manufactures, markets radio-frequency platforms for minimally-invasive procedures, improving existing surgical methods in plastic surgery, gynecology, dermatology, ENT, ophthalmology. | Medical Equipment Manufacturing | 🇺🇸 Irvine | 539 | 2008 |
| 11 | [Rhevera Medical](https://www.tamtam.ai/c/endologix-llc) (endologix.com)<br>Develops therapies for interventional treatment of vascular disease, preserving and restoring blood flow for complex cases like peripheral arterial disease and abdominal aortic aneurysms. | Medical Equipment Manufacturing | 🇺🇸 Irvine | 505 | 1992 |
| 12 | [Beta Bionics](https://www.tamtam.ai/c/beta-bionics) (betabionics.com)<br>Development and commercialization of advanced adaptive algorithm-based autonomous insulin delivery devices to improve diabetes treatment and patient quality of life. | Biotechnology Research | 🇺🇸 Irvine | 425 | 2015 |
| 13 | [Angel Aligner](https://www.tamtam.ai/c/angel-aligner) (angelaligner.com)<br>A global leader in clear aligner technology, driving innovation in orthodontic treatment with over 20 years of experience and a focus on research and digital solutions | Medical Equipment Manufacturing | 🇺🇸 Irvine | 378 | 2003 |
| 14 | [mdxhealth](https://www.tamtam.ai/c/mdxhealth) (mdxhealth.com)<br>Provides actionable molecular diagnostic information to personalize cancer diagnosis and treatment. Tests based on genetic, epigenetic, and molecular technologies for urologic cancers. | Biotechnology Research | 🇺🇸 Irvine | 322 | 2003 |
| 15 | [CERENOVUS](https://www.tamtam.ai/c/cerenovus)<br>A leader in neurovascular care, committed to changing the trajectory of stroke with a broad portfolio of devices for endovascular treatment | Medical Equipment Manufacturing | 🇺🇸 Irvine | 317 | 2017 |
| 16 | [Mentor Worldwide LLC](https://www.tamtam.ai/c/mentor-worldwide-llc) (mentorwwllc.com)<br>A leading global brand specializing in breast aesthetics, developing innovative breast implants with a patient-first approach to empower women's self-esteem and quality of life | Medical Equipment Manufacturing | 🇺🇸 Irvine | 225 | 1984 |
| 17 | [Keystone Dental Group](https://www.tamtam.ai/c/keystone-dental-group) (keystonedental.com)<br>Oral healthcare company delivering breakthrough dental implant and biomaterial technologies, manufacturing premium cutting-edge implants and components through scientific R&D and advanced manufacturing. | Medical Equipment Manufacturing | 🇺🇸 Irvine | 208 | 2006 |
| 18 | [Acclarent](https://www.tamtam.ai/c/acclarent) (products.integralife.com)<br>A medical device company providing minimally invasive technologies for ENT surgeons to treat rhinosinusitis and Eustachian Tube Dysfunction, preserving nasal anatomy | Medical Equipment Manufacturing | 🇺🇸 Irvine | 184 |  |
| 19 | [NeurOptics](https://www.tamtam.ai/c/neuroptics) (neuroptics.com)<br>Leader in NPi Pupillometry technology, providing innovative solutions for improved patient outcomes in various medical disciplines worldwide | Medical Equipment Manufacturing | 🇺🇸 Irvine | 81 | 1995 |
| 20 | [Keating Dental Lab](https://www.tamtam.ai/c/keating-dental-lab) (keatingdentallab.com)<br>Family-run, full-service dental laboratory providing high-quality dental restorations, including dentures, e.max, zirconia, and implant-supported restorations, with 5-star customer service and educational resources. | Medical Equipment Manufacturing | 🇺🇸 Irvine | 73 | 2002 |
| 21 | [LimFlow, Now Part of Stryker](https://www.tamtam.ai/c/limflow-now-part-of-stryker) (limflow.com)<br>LimFlow offers innovative medical technology for end-stage CLTI patients, restoring blood flow to prevent amputations and improve quality of life | Medical Equipment Manufacturing | 🇺🇸 Irvine | 25 | 2012 |
| 22 | [altaviz, llc](https://www.tamtam.ai/c/altaviz-llc) (altaviz.com)<br>Innovative company developing high-performance medical devices and instruments for various industries, focusing on enhancing patient care and safety | Medical Equipment Manufacturing | 🇺🇸 Irvine | 22 | 2012 |
| 23 | [11 Health](https://www.tamtam.ai/c/11-health) (11health.com)<br>Medical wearables company revolutionizing chronic illness management and ostomy life through innovative technology and empathetic patient care | Hospitals and Health Care | 🇺🇸 Irvine | 9 | 2013 |
| 24 | [Rebeccatech LLC](https://www.tamtam.ai/c/rebeccatech-llc) (nebulyft.com)<br>Innovative medical solutions provider specializing in micro-devices, plasma technology, radio-frequency, and device integration for professional care givers | Medical Equipment Manufacturing | 🇺🇸 Irvine | 7 | 2015 |
| 25 | [Hio Medical Resource](https://www.tamtam.ai/c/hio-medical-resource)<br>Provider of top-tier medical supplies to healthcare providers, hospitals, retail brands, and white label partners, dedicated to precision, reliability, and excellence | Medical Equipment Manufacturing | 🇺🇸 Irvine | 3 | 2020 |

## How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 12, 2026.

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Source: https://www.tamtam.ai/l/medical-device-companies-irvine