# Top 50 medical device companies in Spain

Tamtam tracks 72 medical device companies headquartered in Spain. This list ranks the 50 largest by number of employees on LinkedIn, led by Grifols, Werfen and Exeltis. Their median headcount is 194. Half of them were founded in 1995 or later. The most common headquarters are Madrid (6), Barcelona (4) and Sant Cugat del Vallès (3).

These companies are primarily large and mid-sized firms in Spain's medical device and pharmaceutical sectors. They specialize in a range of healthcare solutions, from plasma-derived medicines to diagnostic systems. Grifols is a global healthcare company focusing on plasma-derived medicines, while Werfen specializes in diagnostic solutions. HIPRA develops vaccines for animal and human health, and Impress provides clear aligner orthodontic treatments.

A notable pattern among these companies is the concentration of headquarters in Catalonia, particularly around Barcelona, with several firms also based in Madrid. The firms represent a mix of established players, such as Grifols (founded 1909) and Prim (a Spanish private capital group), alongside more recent ventures like Impress (founded 2019) in orthodontics.

🇪🇸 Spain · 50 companies · Updated Nov 12, 2026

| # | Company | Industry | Headquarters | Employees | Founded |
|---|---|---|---|---|---|
| 1 | [Grifols](https://www.tamtam.ai/c/grifols) (linktr.ee)<br>A global healthcare company specializing in plasma-derived medicines, transfusion medicine, and innovative healthcare solutions, committed to improving people's health worldwide | Pharmaceutical Manufacturing | 🇪🇸 Sant Cugat del Vallès | 14,329 | 1909 |
| 2 | [Werfen](https://www.tamtam.ai/c/werfen) (werfen.com)<br>A global innovator in specialized diagnostics, offering Hemostasis, Acute Care Diagnostics, Transfusion, Autoimmunity, and Transplant solutions through OEM manufacturing and distribution | Medical Equipment Manufacturing | 🇪🇸 L'Hospitalet de Llobregat | 6,858 |  |
| 3 | [Exeltis](https://www.tamtam.ai/c/exeltis) (exeltis.com)<br>Innovative global organization in the pharmaceutical sector, committed to improving health through the development and marketing of medicinal products worldwide | Pharmaceutical Manufacturing | 🇪🇸 Madrid | 2,659 | 2003 |
| 4 | [HIPRA](https://www.tamtam.ai/c/hipra) (hipra.com)<br>Biotechnological pharmaceutical company specializing in innovative vaccines and diagnostic services for animal and human health worldwide | Pharmaceutical Manufacturing | 🇪🇸 Amer | 2,113 |  |
| 5 | [Impress](https://www.tamtam.ai/c/impress) (smile2impress.com)<br>Providing personalized clear aligner orthodontic treatments across Europe and the US, focusing on comfort, discretion, and visible results quickly. | Hospitals and Health Care | 🇪🇸 Barcelona | 1,002 | 2019 |
| 6 | [Prim, S.A.](https://www.tamtam.ai/c/prim-s-a) (prim.es)<br>A Spanish private capital group in the healthcare sector, providing advanced products and solutions to hospitals, clinics, health centers, and individuals | Wellness and Fitness Services | 🇪🇸 Móstoles | 711 |  |
| 7 | [Promedon](https://www.tamtam.ai/c/promedon) (promedon.com)<br>International leader in medical technology research, development, production, and distribution Specializes in Urology, Urogynecology, Sports Medicine, Arthroscopy, and various surgical solutions in multiple countries | Medical Equipment Manufacturing | 🇪🇸 Córdoba | 685 | 1985 |
| 8 | [BioSystems](https://www.tamtam.ai/c/biosystems) (biosystems.global)<br>Global group specializing in In-vitro human and veterinary clinical diagnostics, food & beverage analysis, and bioprocess monitoring, with a focus on user experience and innovation | Biotechnology Research | 🇪🇸 Barcelona | 643 | 1981 |
| 9 | [Hologic (Formerly Gen-Probe)](https://www.tamtam.ai/c/hologic-formerly-gen-probe) (hologic.com)<br>Develops, markets, and services innovative diagnostic imaging systems and surgical products globally, providing greater confidence in diagnoses and enabling healthier lives for people everywhere. | Biotechnology Research | 🇪🇸 | 520 | 1986 |
| 10 | [Roche Diagnostics España](https://www.tamtam.ai/c/roche-diagnostics-espana) (roche.es)<br>A global company pioneering research in diagnostic solutions to advance science, improve lives, and lead personalized medicine with integrated healthcare solutions | Biotechnology Research | 🇪🇸 Sant Cugat del Vallès | 482 | 1896 |
| 11 | [SEDECAL](https://www.tamtam.ai/c/sedecal) (sedecal.com)<br>Global leader in OEM design and manufacturing of high frequency X-Ray generators and systems, with divisions in medical, veterinary, healthcare, and industrial sectors | Medical Equipment Manufacturing | 🇪🇸 Algete | 476 | 1994 |
| 12 | [Idneo](https://www.tamtam.ai/c/idneo) (idneo.com)<br>Engineering service company specializing in design, development, certification, and manufacturing of high-value products across various markets globally. | Appliances, Electrical, and Electronics Manufacturing | 🇪🇸 Mollet del Vallès | 450 | 2011 |
| 13 | [MATACHANA](https://www.tamtam.ai/c/matachana) (matachana.com)<br>A global provider of technological solutions for Healthcare and Life Science sectors, specializing in sterilization, washing, and surgical units With a strong focus on research and development | Machinery Manufacturing | 🇪🇸 Castelldefels | 433 | 1962 |
| 14 | [mesoestetic Pharma Group](https://www.tamtam.ai/c/mesoestetic-pharma-group) (mesoestetic.es)<br>A leading pharmaceutical laboratory specializing in dermatology and aesthetic medicine, offering innovative solutions for skin treatment, including cosmeceuticals and medical devices | Pharmaceutical Manufacturing | 🇪🇸 Viladecans | 424 | 1985 |
| 15 | [Inibsa](https://www.tamtam.ai/c/inibsa) (inibsa.com)<br>A Barcelona-based pharmaceutical company with 75 years of experience, specializing in dental products and services sold in over 60 countries | Pharmaceutical Manufacturing | 🇪🇸 Lliçà de Vall | 411 | 1948 |
| 16 | [Inmunotek](https://www.tamtam.ai/c/inmunotek) (inmunotek.com)<br>A pharma company developing therapeutic vaccines for allergy, infectious diseases, and cancer, as well as medical devices, sold globally Founded in 1992 for patient and healthcare professional benefit | Pharmaceutical Manufacturing | 🇪🇸 Alcalá de Henares | 382 | 1992 |
| 17 | [Werfen Immunoassay](https://www.tamtam.ai/c/werfen-immunoassay) (werfen.com)<br>Specializes in research, development, and manufacturing of customized assays and biomaterials for the IVD industry, enhancing competitiveness and time-to-market | Biotechnology Research | 🇪🇸 Lliçà d'Amunt | 327 | 1973 |
| 18 | [Corus](https://www.tamtam.ai/c/corus) (corusdental.com)<br>A network of dental laboratories in Europe offering innovative products and services for modern dentistry, focusing on quality patient care | Medical Equipment Manufacturing | 🇪🇸 Sant Cugat del Vallès | 323 | 2015 |
| 19 | [Telstar](https://www.tamtam.ai/c/telstar) (telstar.com)<br>Engineering, construction, and integrated process equipment provider specializing in GMP consultancy and aseptic solutions for life sciences, pharmaceutical, biotechnology, and healthcare industries worldwide. | Machinery Manufacturing | 🇪🇸 Terrassa | 321 | 1963 |
| 20 | [MBA SURGICAL EMPOWERMENT](https://www.tamtam.ai/c/mba-surgical-empowerment) (mba.eu)<br>A leading European medical and surgical technology provider offering a wide range of solutions for orthopaedic, neurosurgery, anesthesiology, and other surgical specialties | Medical Equipment Manufacturing | 🇪🇸 Gijón | 309 | 1988 |
| 21 | [AMES - Sintered metallic components](https://www.tamtam.ai/c/ames-sintered-metallic-components) (ames.group)<br>A manufacturing company founded in 1951, specializing in sintered metal components such as structural parts, bearings, filters, membranes, and biomedical implants | Industrial Machinery Manufacturing | 🇪🇸 St. Feliu de Llobregat | 303 | 1951 |
| 22 | [BTI Biotechnology Institute](https://www.tamtam.ai/c/bti-biotechnology-institute) (bti-biotechnologyinstitute.com)<br>A Spanish multinational specializing in regenerative medicine and oral implantology, focused on research, development, and training in biomedicine | Biotechnology Research | 🇪🇸 Vitoria-Gasteiz | 246 | 1995 |
| 23 | [Laboratorios Rubió](https://www.tamtam.ai/c/laboratorios-rubio) (laboratoriosrubio.com)<br>Pharmaceutical company dedicated to providing medications for low-prevalence diseases, ADHD treatment, clinical nutrition, and diagnostics with a focus on accessibility and quality of life | Pharmaceutical Manufacturing | 🇪🇸 Castellbisbal | 243 | 1968 |
| 24 | [Certest Biotec, S.L.](https://www.tamtam.ai/c/certest-biotec-s-l) (certest.es)<br>Specialized company with four divisions providing raw materials, immunodiagnostics, molecular biology solutions, and pharma technology for IVD assays and therapeutic products | Biotechnology Research | 🇪🇸 San Mateo de Gállego | 203 | 2002 |
| 25 | [Fresenius Kabi España](https://www.tamtam.ai/c/fresenius-kabi-espana) (fresenius-kabi.com)<br>Healthcare company providing solutions for healthcare professionals through a wide range of medicines, infusion technologies, clinical nutrition, and medical devices Operating globally with a mission of Advancing Patient Care | Pharmaceutical Manufacturing | 🇪🇸 Barcelona | 194 |  |
| 26 | [Quibim](https://www.tamtam.ai/c/quibim) (quibim.com)<br>Quibim specializes in developing innovative tools that utilize AI to analyze medical imaging data, enabling better patient outcomes and actionable predictions for healthcare | Biotechnology Research | 🇪🇸 Valencia | 120 | 2015 |
| 27 | [IPD Dental Group Iberia](https://www.tamtam.ai/c/ipd-dental-group-iberia) (ipd2004.com)<br>A global leader in designing, manufacturing, and distributing dental implant abutments, providing innovative prosthetic solutions with high-quality products and cutting-edge technology | Medical Equipment Manufacturing | 🇪🇸 Premià de Dalt | 114 | 2004 |
| 28 | [DVD Dental Solutions](https://www.tamtam.ai/c/dvd-dental-solutions) (dvd-dental.com)<br>A leading dental company providing innovative solutions and value for dental professionals, offering a wide range of products and services | Medical Equipment Manufacturing | 🇪🇸 Sant Boi de Llobregat | 102 | 1988 |
| 29 | [Neftis Laboratorios](https://www.tamtam.ai/c/neftis-laboratorios) (neftislaboratorios.com)<br>A Contract Manufacturer specializing in professional cosmetics, Medical Devices, and bespoke formulations, offering technical support and compliance with regulations | Personal Care Product Manufacturing | 🇪🇸 Santa Eulàlia de Ronçana | 86 | 2005 |
| 30 | [Idoven](https://www.tamtam.ai/c/idoven) (idoven.ai)<br>Health technology company utilizing AI for early detection of cardiovascular diseases through ECG interpretation and disease biomarker development for precision medicine | Software Development | 🇪🇸 Madrid | 70 | 2018 |
| 31 | [Ortoprono](https://www.tamtam.ai/c/ortoprono) (ortoprono.es)<br>Ortoprono specializes in technical orthopedics, providing quality products and services for adults and children, collaborating closely with healthcare professionals for innovative solutions | Wellness and Fitness Services | 🇪🇸 Valencia | 69 | 1969 |
| 32 | [SecretAligner](https://www.tamtam.ai/c/secretaligner) (secretaligner.com)<br>Specializing in invisible orthodontics, all cases designed by orthodontists in Spain Continual training and excellence standards upheld | Wellness and Fitness Services | 🇪🇸 Madrid | 58 | 2017 |
| 33 | [Prótesis S.A.](https://www.tamtam.ai/c/protesis-s-a) (protesis.com)<br>The company specializes in all types of dental prosthetics, offering precision implant work, fixed prosthetics with various materials, cosmetic options, and removable prosthetics since 1953 | Wellness and Fitness Services | 🇪🇸 Madrid | 55 |  |
| 34 | [Eckermann](https://www.tamtam.ai/c/eckermann) (eckermann.es)<br>A Spanish company specializing in advanced implantology services, with expertise in manufacturing and a dedicated customer service approach | Wellness and Fitness Services | 🇪🇸 Almoradí | 55 | 1998 |
| 35 | [NESA WORLD](https://www.tamtam.ai/c/nesa-world) (nesa.world)<br>NESA WORLD® is a medical technology company specializing in non-invasive autonomic nervous system rehabilitation, offering innovative microcurrent system for chronic pain relief and stress reduction | Wellness and Fitness Services | 🇪🇸 San Sebastián | 53 |  |
| 36 | [Rob Surgical](https://www.tamtam.ai/c/rob-surgical) (robsurgical.com)<br>Develops a flexible four-arm robotic platform for hybrid surgeries, combining manual and high-precision robot-assisted maneuvers to improve safety and reduce operation costs. | Medical Equipment Manufacturing | 🇪🇸 El Prat de Llobregat | 47 | 2012 |
| 37 | [IRE RAYOS X, S.A.](https://www.tamtam.ai/c/ire-rayos-x-s-a) (irerayosx.com)<br>The company specializes in X-ray equipment and software development for radiology services, offering radiology machinery and digital hospital systems compliant with industry standards | Wellness and Fitness Services | 🇪🇸 San Sebastián de los Reyes | 45 | 1997 |
| 38 | [RÖS'S - Ross estética](https://www.tamtam.ai/c/ros-s-ross-estetica) (ross.international)<br>Manufacturer of advanced technology for aesthetics, physiotherapy, medical aesthetics, and wellness, including tecartherapy, radiofrequency, electrostimulation, and physioactive massage equipment Designed and made in Spain since 1978 | Wellness and Fitness Services | 🇪🇸 Castelldefels | 44 | 1978 |
| 39 | [Ambu - España](https://www.tamtam.ai/c/ambu-espana) (ambu.es)<br>Since 1937, this company has been revolutionizing medical solutions to save lives and improve patient care worldwide through innovative patient monitoring, anesthesia, and endoscopy solutions | Medical Equipment Manufacturing | 🇪🇸 Madrid | 41 | 1937 |
| 40 | [IT Pharma](https://www.tamtam.ai/c/it-pharma) (itpharma.com)<br>A Spanish company in Pamplona specializing in mesotherapy and aesthetic medicine, with over 30 years of experience in developing sterile, personalized products | Personal Care Product Manufacturing | 🇪🇸 Huarte | 41 | 2005 |
| 41 | [FLEXOR S.A.](https://www.tamtam.ai/c/flexor-s-a) (flexor.es)<br>Specializing in latex insoles for healthy and comfortable walking, we aim to improve foot health and comfort since 1963 | Wellness and Fitness Services | 🇪🇸 Barberà del Vallès | 38 | 1963 |
| 42 | [EMO - especialistas en ortopedia](https://www.tamtam.ai/c/emo-especialistas-en-ortopedia) (emo.es)<br>A global leader in orthopedic specialties manufacturing and distribution serving clients in over 30 countries across all continents since 1970 | Wellness and Fitness Services | 🇪🇸 Paiporta | 37 | 1970 |
| 43 | [Corus OrthoLab](https://www.tamtam.ai/c/corus-ortholab) (clubortholab.es)<br>A company specializing in supplying dental clinics with products, laboratory services, and training for various specialties in the dental field | Wellness and Fitness Services | 🇪🇸 Elda | 35 | 2005 |
| 44 | [DyCare - Digital Rehabilitation](https://www.tamtam.ai/c/dycare-digital-rehabilitation) (dycare.com)<br>The company provides innovative digital solutions in the rehabilitation sector, improving diagnosis quality, monitoring recovery, and personalizing patient follow-up for professionals and healthcare institutions | Wellness and Fitness Services | 🇪🇸 Barcelona | 31 | 2015 |
| 45 | [Bader Dental](https://www.tamtam.ai/c/bader-dental) (bader.es)<br>A Spanish company specializing in manufacturing, importing, and exporting dental instruments They offer a personalized approach and full solutions to dental distributors | Medical Equipment Manufacturing | 🇪🇸 Nigrán | 27 | 2007 |
| 46 | [Medicsen](https://www.tamtam.ai/c/medicsen) (medicsen.com)<br>A Spanish startup developing a revolutionary diabetes treatment with an app for glucose monitoring and insulin delivery patch, seeking patient support and collaboration opportunities | Medical Equipment Manufacturing | 🇪🇸 Madrid | 24 | 2015 |
| 47 | [Aragoneses CPD Dental Lab](https://www.tamtam.ai/c/aragoneses-cpd-dental-lab) (aragonesescpd.com)<br>Aragoneses CPD is a dental laboratory with over 70 years of experience, creating personalized prostheses using the latest technology and traditional techniques for clients in Spain and Europe | Wellness and Fitness Services | 🇪🇸 Alcobendas | 24 | 1950 |
| 48 | [KMINA](https://www.tamtam.ai/c/kmina) (kmina.com)<br>A European company specializing in developing and distributing orthopedic and health solutions to improve mobility and daily life for clients globally | Wellness and Fitness Services | 🇪🇸 Valencia | 23 | 2016 |
| 49 | [SINELDENT®](https://www.tamtam.ai/c/sineldent) (sineldent.com)<br>Specialized in CAD/CAM dental prosthesis manufacturing using additive technology, contributing to dental lab modernization and digital workflow development within the market segments | Wellness and Fitness Services | 🇪🇸 Ourense | 23 | 2008 |
| 50 | [OrthoApnea](https://www.tamtam.ai/c/orthoapnea) (orthoapnea.com)<br>OrthoApnea provides high-quality Sleep Apnea Oral Appliances to improve patients' health, well-being, and happiness through compassionate care and advanced techniques | Wellness and Fitness Services | 🇪🇸 Málaga | 23 | 2009 |

## How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 12, 2026.

## More company lists in Spain

- [The largest companies in Spain](https://www.tamtam.ai/l/largest-companies-spain) (10,893)
- [Multinational companies in Spain](https://www.tamtam.ai/l/multinational-companies-spain) (2,706)
- [Retail chains in Spain](https://www.tamtam.ai/l/retail-chains-spain) (1,251)
- [Manufacturers in Spain](https://www.tamtam.ai/l/manufacturers-spain) (1,080)
- [Companies with in-house R&D in Spain](https://www.tamtam.ai/l/r-and-d-companies-spain) (1,067)
- [Wellness and Fitness Services companies in Spain](https://www.tamtam.ai/l/wellness-and-fitness-services-companies-spain) (879)
- [Healthcare providers in Spain](https://www.tamtam.ai/l/healthcare-providers-spain) (711)
- [Companies with a mobile app in Spain](https://www.tamtam.ai/l/companies-with-mobile-app-spain) (561)
- [Hotel and hospitality groups in Spain](https://www.tamtam.ai/l/hospitality-groups-spain) (539)
- [Family-owned companies in Spain](https://www.tamtam.ai/l/family-owned-companies-spain) (531)
- [Software Development companies in Spain](https://www.tamtam.ai/l/software-development-companies-spain) (530)
- [Professional services firms in Spain](https://www.tamtam.ai/l/professional-services-firms-spain) (522)
- [Critical infrastructure operators in Spain](https://www.tamtam.ai/l/critical-infrastructure-operators-spain) (517)
- [IT services companies in Spain](https://www.tamtam.ai/l/it-services-companies-spain) (484)
- [Financial services firms in Spain](https://www.tamtam.ai/l/financial-services-firms-spain) (482)
- [Food and Beverage Services companies in Spain](https://www.tamtam.ai/l/food-and-beverage-services-companies-spain) (462)
- [SaaS companies in Spain](https://www.tamtam.ai/l/saas-companies-spain) (445)
- [Retail Apparel and Fashion companies in Spain](https://www.tamtam.ai/l/retail-apparel-and-fashion-companies-spain) (439)
- [IT Services and IT Consulting companies in Spain](https://www.tamtam.ai/l/it-services-and-it-consulting-companies-spain) (437)
- [Hospitality companies in Spain](https://www.tamtam.ai/l/hospitality-companies-spain) (435)
- [Consulting firms in Spain](https://www.tamtam.ai/l/consulting-firms-spain) (420)
- [E-commerce companies in Spain](https://www.tamtam.ai/l/ecommerce-companies-spain) (416)
- [Food and beverage companies in Spain](https://www.tamtam.ai/l/food-and-beverage-companies-spain) (416)
- [Hardware manufacturers in Spain](https://www.tamtam.ai/l/hardware-companies-spain) (415)

## The same list elsewhere in Spain

- [Medical device companies in Catalonia](https://www.tamtam.ai/l/medical-device-companies-catalonia) (36)

## The same list elsewhere

- [Medical device companies in the world](https://www.tamtam.ai/l/medical-device-companies-in-the-world) (3,415)
- [Medical device companies in Europe](https://www.tamtam.ai/l/medical-device-companies-in-europe) (2,132)

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Source: https://www.tamtam.ai/l/medical-device-companies-spain