The multinational companies operating in Hesse are mostly large, well-established firms with a strong presence in financial services, healthcare, and manufacturing. Many were founded in the 20th century or earlier, indicating their long-standing impact. Deutsche Bank, founded in 1870, provides global financial services, while Merck Group, established in 1668, is a science and technology company. Fresenius Medical Care (1996) specializes in renal disease products, and Lufthansa (1953) is a major airline.
A significant concentration of these companies, including Deutsche Bank, Lufthansa, AUMOVIO, and PwC Deutschland, have their headquarters in Frankfurt. This suggests a strong economic hub in the city, drawing in diverse industries from aviation and automotive to financial and consulting services.
| # | Company | Employees | |||
|---|---|---|---|---|---|
| 1 |
Fresenius Medical Carefreseniusmedicalcare.com
Global leader in renal disease products and services, providing tailored dialysis treatments for improved quality of life for patients worldwide |
128,000 | |||
| 2 |
Lufthansalufthansa.com
Connecting passengers globally, shaping sustainable aviation, offering premium travel experiences, and enhancing customer comfort with advanced technology and services. |
110,000 | |||
| 3 |
Deutsche Bankdb.com
Offers financial services to companies, governments, institutions, small businesses, and individuals globally. Focuses on corporate, private, and investment banking, plus asset management. |
81,792 | |||
| 4 |
Lufthansa Grouplufthansagroup.com
Leading aviation company operating passenger airlines including network and point-to-point carriers, logistics, maintenance, catering, training, and IT systems worldwide. |
49,869 | |||
| 5 |
Merck Groupemdgroup.com
Global science and technology innovations providing solutions in healthcare, life science, and electronics to enrich lives through sustainable research and diverse expertise. |
32,730 | |||
| 6 |
B. Braun Groupbbraun.com
A leading medical technology organization dedicated to protecting and improving global health through innovative solutions and collaborative culture |
29,535 | |||
| 7 |
Fresenius Kabifresenius-kabi.com
Global provider therapies, medical products. Focuses on medicines, technologies for critically, chronically ill patients. Biosimilars, nutrition, medical devices, generics. |
25,432 | |||
| 8 |
AUMOVIOaumovio.com
Provides innovative hardware, software, modern mobility solutions, and a wide range of mobility services, making future mobility safe, exciting, connected, and autonomous. |
20,389 | |||
| 9 |
Commerzbank AGcommerzbank.de
Leading financial institution serving German Mittelstand, corporate groups, and private customers through comprehensive banking services, foreign trade financing, and digital retail solutions. |
12,737 | |||
| 10 |
PwC Deutschlandpwc.de
A leading auditing and consulting firm in Germany, offering services worldwide with expertise in assurance, tax, legal, deals, and strategy advisory |
11,566 | |||
| 11 |
T-Systems Internationalt-systems.com
Provides end-to-end IT solutions, cloud migration, and industry-specific digital transformation services with strong security and global presence. |
10,768 | |||
| 12 |
LSG Grouplsg-group.com
Quality technology leader airline catering, onboard retail with two brands: global catering hospitality specialist, onboard retail product innovation. |
9,031 | |||
| 13 |
Merck Life Sciencesigmaaldrich.com
Global science and technology company providing tools, services, and expertise for researchers in pharmaceutical development, manufacturing, and contract testing across various modalities |
8,700 | |||
| 14 |
EDAG Groupedag.com
Engineering service provider for mobility, defense, industry, and public solutions, developing complex products, systems, and production solutions with an interdisciplinary team. |
8,500 | |||
| 15 |
DVAGdvag-karriere.de
A company founded in 1976 in Germany, providing comprehensive financial services including insurance, annuities, savings, financing, and mutual funds for individual clients |
8,324 | |||
| 16 | 7,944 | ||||
| 17 |
Merck KGaA, Darmstadt, Germanyemdgroup.com
A global science and technology company focused on innovating solutions in Life Science, Healthcare, and Electronics, with a strong emphasis on sustainability and inclusivity |
7,263 | |||
| 18 |
Merck Healthcaremerckgroup.com
The company is dedicated to advancing cancer treatment, improving care for chronic diseases, and helping couples achieve their dream of having a baby through innovative therapies and technologies |
7,065 | |||
| 19 |
STADA Groupstada.com
A leading pharmaceutical manufacturer providing high-quality products globally, focused on consumer healthcare, generics, and specialty pharma, with a commitment to employee development |
6,554 | |||
| 20 | 5,994 | ||||
| 21 |
European Central Bankecb.europa.eu
Central bank maintaining the euro's purchasing power and price stability across 21 European Union countries using the single currency since 1999. |
5,044 | |||
| 22 |
DΓΆhlerGroupdoehler.com
Global provider of natural ingredients, solutions, and technology for food, beverage, and nutrition industries, focusing on sensory performance, nutrition, and sustainability |
4,778 | |||
| 23 | 4,662 | ||||
| 24 |
DZ BANK AGdzbank.de
The company is the central institution in the cooperative financial network in Germany, offering a wide range of financial products and services |
4,645 | |||
| 25 |
Bosch Home Comfort Groupbosch-homecomfortgroup.com
The company specializes in creating innovative sustainable heating, cooling, and well-being solutions to enhance lifestyles for a smarter future |
4,606 | |||
| 26 |
Deutsche BΓΆrse Groupdeutsche-boerse.com
Provides access to global capital markets through securities and derivatives trading, clearing, settlement, custody, market data, and electronic trading systems. |
4,458 | |||
| 27 | 4,308 | ||||
| 28 |
Accenture DACHaccenture.com
A global consulting firm specializing in strategy, management, digitalization, technology, and business transformation, guiding clients through innovation and operational execution |
3,934 | |||
| 29 |
Deutsche Bundesbankbundesbank.de
Central bank operating at financial markets, politics, economy, science intersections, promoting digitalization, societal change, and employee development. |
3,520 | |||
| 30 |
KION Groupkiongroup.com
Architects global, regional, and local supply chains, providing solutions for fast, efficient, smart, sustainable, and reliable material handling and automation worldwide. |
3,498 | |||
| 31 |
Apleona Groupapleona.com
A leading European provider of real estate and facility services with integrated facility management, building technology, real estate management, and commercial services |
3,351 | |||
| 32 |
Fraport AGfraport.com
A leading international airport business with operations on four continents, focusing on passenger and cargo services, providing industry insights and networking opportunities |
3,267 | |||
| 33 |
Bosch Service Solutionsboschservicesolutions.com
Leading global supplier of Business Process Outsourcing for complex business processes. Develops integrated, innovative service solutions in Mobility, Monitoring, and Customer Experience, utilizing latest technology and IoT. |
3,169 | |||
| 34 |
Viessmann Climate Solutionsviessmann-climatesolutions.com
Leading provider of climate and renewable energy solutions, specializing in heating, water, and air quality technologies since 1917 Creating sustainable living spaces |
3,115 | |||
| 35 |
Heraeusheraeus.com
A globally leading family-owned technology company with diverse activities in metals, healthcare, semiconductor, electronics, and industrials, providing innovative solutions worldwide |
2,914 | |||
| 36 |
Lufthansa Cargolufthansa-cargo.com
Global airfreight transport specializing in airport-to-airport cargo services using freighter and passenger aircraft across 300 destinations. |
2,758 | |||
| 37 | 2,673 | ||||
| 38 |
NORMA Groupnormagroup.com
provides engineered joining and fluid-handling solutions for vehicles, water systems, ships, aircraft, supporting climate and resource efficiency |
2,456 | |||
| 39 |
Leica Microsystemsleica-microsystems.com
Development and manufacturing of microscopes and scientific instruments for microstructure and nanostructure analysis with global presence. |
2,407 | |||
| 40 |
ING Deutschlanding.de
A leading digital and universal bank in Germany, known for its agile and innovative methods, teamwork culture, and focus on employee well-being and development |
2,322 | |||
| 41 |
Lufthansa Systemslhsystems.com
provides advanced IT solutions and software for airlines, covering flight deck, cabin, and ground operations worldwide. |
2,282 | |||
| 42 |
allnexallnex.com
A leading producer of specialty polymers focused on sustainability, offering advanced coating solutions for various industries through global innovation and responsive local support |
2,259 | |||
| 43 |
Condor Airlinescondor.com
Flies guests to over 70 destinations worldwide since 1956, connecting Europe, Africa, Asia, and North America, with an ongoing fleet modernization and new brand identity. |
2,238 | |||
| 44 |
Schunk Groupschunk-group.com
A global technology group with expertise in carbon, ceramics, and sintered metal products, environmental simulation, air conditioning, ultrasonic welding, and optical production |
2,179 | |||
| 45 |
DB Fernverkehr AGdeutschebahn.com
A railway company specializing in long-distance passenger transportation, operating as a subsidiary of Deutsche Bahn AG in Frankfurt, Germany |
2,162 | |||
| 46 |
K+S Groupkpluss.com
A customer-focused supplier of mineral products for agriculture, industry, consumers, and communities, with a commitment to sustainability and global distribution network |
2,157 | |||
| 47 |
Fresenius Groupfresenius.com
A leading healthcare company offering system-critical products and services for therapy, with a focus on advancing patient care and improving medicine for more people |
2,092 | |||
| 48 |
SGL Carbonsglcarbon.com
Global leader in carbon-based solutions for industries such as automotive, semiconductor, energy, and chemicals Committed to sustainability and innovation |
2,079 | |||
| 49 |
Mewamewa-service.com
Provides workwear, protective clothing, hygiene solutions, mats, and safety equipment to companies across Europe for workplace safety and cleanliness. |
2,050 | |||
| 50 |
Internationaler Bund (IB)internationaler-bund.de
A leading service provider in youth, social, and educational work, with a global presence in over 60 countries, focusing on personal development and societal integration |
2,028 | |||
Want more companies than this list?This page shows the largest ones only. Connect to Tamtam to see every company that matches, filter by size, industry or growth, and reach their decision-makers. | |||||
| 51 |
Regnologyregnology.net
Provides technology for regulatory, risk, tax, and finance reporting, helping clients achieve compliance and unlock insights across various financial sectors globally. |
2,015 | |||
| 52 |
INEOS Styrolutionineos.com
Global leader in styrenics supply, specializing in styrene monomer, polystyrene, ABS, and styrenic specialties for various industries, with world-class production facilities and 90+ years of experience |
1,978 | |||
| 53 |
Hyundai GLOVIS Europeglovis.eu
Worldwide automotive logistics and supply chain management including production components, vehicle delivery, spare parts distribution, and operation of transport fleets. |
1,913 | |||
| 54 |
Frankfurt School of Finance & Managementfrankfurt-school.de
A research-led business school specializing in finance, economics, and management, offering Bachelor, Master, MBA, doctoral programs, executive education, and consulting services |
1,909 | |||
| 55 |
Schenck Processqlar.com
A global leader in engineering technologies with expertise in industrial weighing, feeding, conveying, milling, grinding, and digital applications for material processing |
1,900 | |||
| 56 |
Software AGsoftwareag.com
Helps enterprises modernize and integrate core business applications for security, efficiency, and long-term value, enabling innovation without disruption for organizations worldwide. |
1,884 | |||
| 57 |
Helabahelaba.com
The company is a leading financial institution in Frankfurt, offering comprehensive financial services to businesses, banks, and institutional investors, as well as innovative products to Sparkassen |
1,864 | |||
| 58 |
d-fined-fine.com
European consultancy specializing in data science, technology, and mathematical modeling with diverse teams and flexible working models. |
1,785 | |||
| 59 |
DFS Deutsche Flugsicherung GmbHdfs.de
A German air navigation service provider with 5,600 employees ensuring safe and punctual air traffic flow, guiding millions of flights annually |
1,767 | |||
| 60 |
Pfeiffer Vacuum+Fab Solutionspfeiffer-vacuum.com
A global leader in vacuum technology solutions, offering a range of products and services including turbopumps, leak detectors, and vacuum systems with top-tier customer support |
1,764 | |||
| 61 |
PharmaLexpharmalex.com
Global pharmaceutical solutions organization providing support to pharma, biotech, and medtech industries through strategic planning, clinical development, regulatory submissions, and post-launch activities |
1,739 | |||
| 62 |
Chemetallchemetall.com
Leading supplier of applied surface treatment technologies for metal, plastic, and glass substrates in industries like automotive, aerospace, and aluminum finishing |
1,728 | |||
| 63 |
Condor Flugdienst GmbHcondor.com
Flies guests to holiday destinations from German and Swiss airports, operating a fleet of over 50 aircraft, including new A330neo and A32Xneo models. |
1,727 | |||
| 64 |
MTI Technology GmbHde.mti.com
A reliable partner offering storage, backup, datacenter optimization, security, cloud solutions, and managed services to guide businesses through digital transformation successfully |
1,655 | |||
| 65 |
BRITA Groupbrita.nl
Develops, produces, distributes innovative water filtration products for private and commercial use, including jugs, systems, dispensers, and sparkling water makers. |
1,654 | |||
| 66 |
DQSdqsglobal.com
International headquarters overseeing 85 offices in 60 countries, providing top 10 certification services for management systems with 2,500 auditors and expertise in various sectors |
1,611 | |||
| 67 |
AuPairWorldaupairworld.com
Connecting families and young people for cultural exchange and work-life balance through the largest au pair placement internet platform since 1999 |
1,588 | |||
| 68 |
Standard Profil Groupstandardprofil.com
A global supplier of automotive sealing solutions, prioritizing safety and comfort Specializing in innovative and sustainable products for major automakers worldwide |
1,560 | |||
| 69 |
Henkell Freixenethenkell-freixenet.com
Global producer of sparkling wine, branded wines, and spirits with a diverse portfolio of international and local iconic brands, creating meaningful consumer experiences worldwide |
1,548 | |||
| 70 |
Steigenberger Hotels and Resortshrewards.com
Luxury hospitality with 60 hotels worldwide, offering character, elegance, and top-notch service for business guests with state-of-the-art facilities and event organization support |
1,535 | |||
| 71 |
Techem Energy Services GmbHtechem.com
Global energy service provider promoting awareness of energy and water consumption for real estate sector and homeowners in over 20 countries Over 3,500 employees worldwide |
1,442 | |||
| 72 |
STRABAG Property and Facility Services Groupstrabag-pfs.com
International real estate and industrial service provider offering property and facility management, technical and infrastructural services across various sectors with a focus on innovation and digitalization |
1,413 | |||
| 73 |
Randstad Deutschlandrandstad.de
Connecting specialized talents with companies worldwide, building diverse and agile teams, and providing equitable career opportunities. |
1,393 | |||
| 74 |
Lufthansa Group Business Serviceslufthansa-group-business-services.com
Global provider of Finance, Revenue Accounting, Human Resources, and Procurement services, focused on increasing efficiency and generating cost savings for its parent company |
1,352 | |||
| 75 |
Deutsche Leasing Gruppedeutsche-leasing.com
Leading independent leasing company in Germany offering comprehensive asset finance solutions and expertise tailored to each client's needs, backed by Sparkassen-Finanzgruppe's stability and trustworthiness |
1,345 | |||
| 76 |
Universal-Investmentuniversal-investment.com
Providing comprehensive fund services and administration for asset managers and institutional investors across multiple European domiciles with regulatory compliance. |
1,343 | |||
| 77 |
Merz Therapeuticsmerztherapeutics.com
Development of innovative treatments and partnerships for movement disorders, neurodegenerative diseases, liver disease, improving patient quality of life globally. |
1,322 | |||
| 78 |
Emma β The Sleep Companyteam.emma-sleep.com
Development and promotion of advanced sleep technology products aimed at improving rest quality and supporting diverse, inclusive work culture. |
1,317 | |||
| 79 |
Bosch Thermotechnik GmbHbosch-homecomfort.com
A global leader specializing in providing advanced thermotechnology solutions aimed at enhancing home comfort through innovative heating and cooling products |
1,253 | |||
| 80 |
Helvetia Deutschlandhelvetia.de
Providing innovative, customer-focused insurance and pension solutions for private customers and SMEs across life, property, and personal insurance sectors. |
1,205 | |||
| 81 |
Woco Groupwocogroup.com
A technology company specializing in smart solutions for automotive and industrial sectors, focusing on noise reduction, fluid regulation, and emissions reduction |
1,169 | |||
| 82 |
ProCredit Holdingprocredit-holding.com
A multinational banking group focuses on providing sustainable banking services to SMEs and private clients, emphasizing impact-oriented practices and cultural diversity |
1,163 | |||
| 83 |
DERTOUR Deutschlanddertour-jobs.com
A leading travel group in Europe with a diverse portfolio of travel brands, offering holidays and personalized service through multiple distribution channels |
1,149 | |||
| 84 |
Messe Frankfurt GmbHmessefrankfurt.com
Organizes global trade fairs and congresses while providing exhibition ground rentals, event construction, marketing, personnel, and catering services across a worldwide sales network. |
1,147 | |||
| 85 |
SAMSON GROUPsamsongroup.com
A leading manufacturer of control valves, butterfly valves, automation units, regulators, transmitters, and controllers for industrial processes, with a focus on innovation and digitization |
1,144 | |||
| 86 |
Bethmann HALbethmannbank.de
An established German bank with over 300 years of experience in private banking, offering personalized wealth management solutions and international investment opportunities |
1,124 | |||
| 87 |
Castolin Eutecticcastolin.com
providing innovative welding, brazing, and coating technologies to extend equipment life, reduce maintenance costs, and boost productivity |
1,099 | |||
| 88 |
H World Internationalint.hworld.com
A global hotel company with diverse brands and an innovative loyalty program, focusing on international expansion through lease, management, and franchise models |
1,088 | |||
| 89 |
Biotest GmbH & Co. KGaAbiotest.com
Specialist supplier of plasma proteins and biotherapeutic drugs for immune and hematopoietic diseases, with a focus on innovative treatments and global reach |
1,076 | |||
| 90 |
Discover Airlinesdiscover-airlines.com
A leisure airline in Germany, part of the Lufthansa Group, offering flights to popular holiday destinations with modern amenities and excellent service |
1,052 | |||
| 91 |
flatexDEGIROflatexdegiro.com
Europe's leading online brokerage platforms offer a wide range of products with top-tier execution, aiming to grow customer base and transactions significantly |
1,048 | |||
| 92 |
AirPlusairplus.com
AirPlus simplifies corporate payments with central accounts, credit cards, digital procurement tools, and data intelligence solutions for businesses worldwide |
1,029 | |||
| 93 |
Wintershall Deawintershalldea.com
A leading European gas and oil company transitioning to focus on gas, carbon management, and low carbon hydrogen projects globally |
1,026 | |||
| 94 | 1,022 | ||||
| 95 |
Dorsch Gruppedorsch.com
An innovative consulting and engineering partner with a focus on transport, water, architecture, energy, and industry projects globally |
1,001 | |||
| 96 |
Nintendo of Europenintendo.com
A Japanese company creates popular video game franchises, hardware, and software products, aiming to provide unique entertainment experiences globally |
998 | |||
| 97 |
Merck Electronicsmerckgroup.com
Innovative materials and solutions in semiconductor, display, and surface technologies, driving forward electronics advancements for a data-driven world |
997 | |||
| 98 | 993 | ||||
| 99 | 980 | ||||
| 100 | 971 | ||||
Turn this list into pipeline
Tamtam finds the decision-makers at every company on a list like this one, with verified emails, phone numbers and the buying signals that tell you when to reach out.
How this list is built
Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 11, 2026.
More company lists in Hesse
- The largest companies in Hesse 1,378
- Financial services firms in Hesse 205
- Companies with in-house R&D in Hesse 200
- Manufacturers in Hesse 163
- Critical infrastructure operators in Hesse 156
- Financial Services companies in Hesse 141
- Transportation, Logistics, Supply Chain and Storage companies in Hesse 124
- Retail chains in Hesse 110
- SaaS companies in Hesse 94
- Hardware manufacturers in Hesse 93
- Family-owned companies in Hesse 88
- Professional services firms in Hesse 88
- Software Development companies in Hesse 86
- IT Services and IT Consulting companies in Hesse 80
- Banking companies in Hesse 77
- Consulting firms in Hesse 74
- IT services companies in Hesse 66
- Corporate groups and holding companies in Hesse 65
- Public sector organisations in Hesse 65
- Companies with a mobile app in Hesse 61
- Logistics companies in Hesse 57
- Publicly traded companies in Hesse 53
- Automotive manufacturers and suppliers in Hesse 45
- Chemical companies in Hesse 45
The same list elsewhere in Germany
- Multinational companies in Germany 4,800
- Multinational companies in North Rhine-Westphalia 996
- Multinational companies in Bavaria 958
- Multinational companies in Baden-WΓΌrttemberg 781
- Multinational companies in Lower Saxony 242
- Multinational companies in Rhineland-Palatinate 117
- Multinational companies in Schleswig-Holstein 85
- Multinational companies in Saxony 67
- Multinational companies in Berlin 442
- Multinational companies in Munich 382
- Multinational companies in Hamburg 320
- Multinational companies in Frankfurt 178
- Multinational companies in Cologne 135
- Multinational companies in DΓΌsseldorf 132
- Multinational companies in Stuttgart 99
- Multinational companies in Bremen 65
- Multinational companies in Bonn 54
- Multinational companies in Hanover 45
- Multinational companies in Nuremberg 44
- Multinational companies in Mannheim 42
- Multinational companies in Essen 41
- Multinational companies in Karlsruhe 36
- Multinational companies in Aachen 33
- Multinational companies in Wiesbaden 30