# 50 leading multinational companies in Missouri

Tamtam tracks 201 multinational companies headquartered in Missouri. This list ranks the 50 largest by number of employees on LinkedIn, led by O'Reilly Auto Parts, Enterprise Mobility and Emerson. Their median headcount is 4,395. Half of them were founded in 1915 or later. The most common headquarters are St. Louis (24), Chesterfield (7) and Kansas City (7).

This selection of multinational companies in Missouri shows a strong presence of large, established firms across diverse sectors. Key players include O'Reilly Auto Parts, a major automotive aftermarket retailer; Enterprise Mobility, offering global transportation solutions; Emerson, a technology and engineering firm; and Edward Jones, providing financial advisory services. These companies are well-known for their extensive operations and significant employee bases.

A notable pattern is the concentration of headquarters in St. Louis, which hosts a significant number of these large multinationals, including Enterprise Mobility, Emerson, and Edward Jones. Other major cities like Kansas City and Springfield also feature prominently, indicating a broad distribution of economic activity across the state.

🇺🇸 Missouri · 50 companies · Updated Nov 11, 2026

| # | Company | Industry | Headquarters | Employees | Founded |
|---|---|---|---|---|---|
| 1 | [O'Reilly Auto Parts](https://www.tamtam.ai/c/o-reilly-auto-parts) (oreillyauto.com)<br>A leading retailer in the automotive aftermarket industry with over 6,000+ locations, committed to serving customers, community, and team members | Retail | 🇺🇸 Springfield | 84,000 | 1957 |
| 2 | [Enterprise Mobility](https://www.tamtam.ai/c/enterprise-mobility) (enterprisemobility.com)<br>Provides comprehensive mobility solutions worldwide, focusing on innovative, accessible, efficient, and sustainable transportation for people and goods. | Travel Arrangements | 🇺🇸 St. Louis | 70,005 |  |
| 3 | [Emerson](https://www.tamtam.ai/c/emerson) (emerson.com)<br>A global technology and engineering company providing innovative solutions for industrial and commercial markets, driving innovation for a healthier, safer, and smarter world | Automation Machinery Manufacturing | 🇺🇸 St. Louis | 51,841 | 1890 |
| 4 | [Edward Jones](https://www.tamtam.ai/c/edward-jones-st-louis) (edwardjones.com)<br>Provides personalized financial advisory and investment services through a large network of advisors to help clients achieve financial goals. | Financial Services | 🇺🇸 St. Louis | 45,845 | 1922 |
| 5 | [Amdocs](https://www.tamtam.ai/c/amdocs) (amdocs.com)<br>A global company empowers clients to innovate and create exceptional digital experiences, accelerate cloud migration, differentiate in 5G era, and enhance communication and media experiences | Software Development | 🇺🇸 Chesterfield | 34,637 |  |
| 6 | [Enterprise](https://www.tamtam.ai/c/enterprise) (enterprisemobility.com)<br>Provides car rental services globally through multiple brands, offering employment opportunities and vehicle access in many countries. | Travel Arrangements | 🇺🇸 St. Louis | 32,638 |  |
| 7 | [Bunge](https://www.tamtam.ai/c/bunge) (bunge.com)<br>Connecting farmers to consumers by moving agricultural commodities globally, processing oilseeds, and delivering plant-based food, feed, and fuel products. | Food and Beverage Manufacturing | 🇺🇸 Chesterfield | 26,107 | 1818 |
| 8 | [Wal Mart Corporation](https://www.tamtam.ai/c/wal-mart-corporation)<br>This company provides access to Walmart executive speeches, financial reports, press releases, photos, videos, and interactive global location map | Entertainment Providers | 🇺🇸 Sikeston | 19,478 |  |
| 9 | [Hallmark Cards](https://www.tamtam.ai/c/hallmark-cards) (careers.hallmark.com)<br>Family-owned global business creating emotionally connected world through greeting cards, gifts, media networks, real estate development, and art products for children worldwide | Retail | 🇺🇸 Kansas City | 17,388 | 1910 |
| 10 | [Burns & McDonnell](https://www.tamtam.ai/c/burns-and-mcdonnell) (burnsmcd.com)<br>Engineering, construction, architecture, planning, and community engagement with a strong ownership mentality and commitment to client success and safety. | Construction | 🇺🇸 Kansas City | 16,200 |  |
| 11 | [Caleres, Inc.](https://www.tamtam.ai/c/caleres-inc) (jobs.caleres.com)<br>This company is a global footwear brand portfolio with diverse offerings, including famous labels like Sam Edelman and Naturalizer, focusing on consumer-driven innovation and quality craftsmanship | Retail Apparel and Fashion | 🇺🇸 St. Louis | 9,313 | 1878 |
| 12 | [Monsanto Company](https://www.tamtam.ai/c/monsanto-company) (bayer.com)<br>Leading in modern agriculture with a focus on seeds, plant traits, and crop protection through innovative breakthroughs for global impact | Farming | 🇺🇸 St. Louis | 9,303 |  |
| 13 | [Nestlé Purina North America](https://www.tamtam.ai/c/nestle-purina-north-america) (purinajobs.com)<br>Advances pet nutrition science, collaborates on innovation, and enriches lives of pets and owners. Builds strong teams for pet care. | Manufacturing | 🇺🇸 St. Louis | 8,321 | 1894 |
| 14 | [Graybar](https://www.tamtam.ai/c/graybar) (graybar.com)<br>A Fortune 500 employee-owned corporation distributes electrical, communications, and networking products, offering supply chain management and logistics services to customers | Wholesale | 🇺🇸 St. Louis | 8,118 | 1869 |
| 15 | [Saint Louis University](https://www.tamtam.ai/c/saint-louis-university) (slu.edu)<br>A Jesuit, Catholic university in St Louis, MO offering top research programs Oldest university in the West, with a campus in Madrid, Spain | Higher Education | 🇺🇸 St. Louis | 7,855 | 1818 |
| 16 | [Stifel Financial Corp.](https://www.tamtam.ai/c/stifel-financial-corp) (stifel.com)<br>Providing brokerage, trading, investment banking, advisory, and trust services to individuals, businesses, and municipalities across the U.S. | Financial Services | 🇺🇸 St. Louis | 7,384 | 1890 |
| 17 | [Anheuser-Busch](https://www.tamtam.ai/c/anheuser-busch) (anheuser-busch.com)<br>A leading brewer in the United States with a legacy of crafting high-quality beers, supporting communities, and valuing talented employees | Food and Beverage Services | 🇺🇸 St. Louis | 7,091 | 1852 |
| 18 | [Premium Retail Services](https://www.tamtam.ai/c/premium-retail-services) (premiumretail.com)<br>A leading company in the US and Canada helps brands develop winning retail strategies, train associates, engage customers, and drive sales growth | Retail | 🇺🇸 Chesterfield | 6,209 | 1985 |
| 19 | [Energizer Holdings](https://www.tamtam.ai/c/energizer-holdings) (energizerholdings.com)<br>A global organization creating innovative products to improve lives, focused on serving customers, driving revenue, and delivering long-term value | Manufacturing | 🇺🇸 St. Louis | 6,098 | 1896 |
| 20 | [Missouri State University](https://www.tamtam.ai/c/missouri-state-university) (missouristate.edu)<br>The company focuses on community engagement, ethical leadership, and cultural competence as part of Missouri State's public affairs mission | Higher Education | 🇺🇸 Springfield | 5,090 | 1905 |
| 21 | [Nidec Motor Corporation](https://www.tamtam.ai/c/nidec-motor-corporation) (acim.nidec.com)<br>manufacture high efficiency commercial and industrial motors, controls, and generators for applications in water treatment, mining, oil, gas, and refrigeration | Appliances, Electrical, and Electronics Manufacturing | 🇺🇸 Creve Coeur | 5,082 |  |
| 22 | [Copeland](https://www.tamtam.ai/c/copeland) (copeland.com)<br>Develop sustainable HVACR technologies for residential, commercial, and industrial spaces, ensuring cold chain integrity and global comfort. | Climate Technology Product Manufacturing | 🇺🇸 St. Louis | 4,804 |  |
| 23 | [Leggett & Platt](https://www.tamtam.ai/c/leggett-and-platt) (leggett.com)<br>Designing and manufacturing innovative products and components for bedding, furniture, seating, homes, offices, airplanes, and automobiles worldwide. | Furniture and Home Furnishings Manufacturing | 🇺🇸 Carthage | 4,601 | 1883 |
| 24 | [Reinsurance Group of America, Incorporated](https://www.tamtam.ai/c/reinsurance-group-of-america-incorporated) (rgare.com)<br>Global leader in life and health reinsurance providing financial solutions to manage risk, optimize capital, and ensure financial protection accessibility. | Insurance | 🇺🇸 Chesterfield | 4,444 | 1973 |
| 25 | [Barry-Wehmiller](https://www.tamtam.ai/c/barry-wehmiller) (barrywehmiller.com)<br>The company is dedicated to improving the lives of its global team through meaningful work, care, compassion, and personal growth initiatives | Machinery Manufacturing | 🇺🇸 St. Louis | 4,395 |  |
| 26 | [Perficient](https://www.tamtam.ai/c/perficient) (perficient.com)<br>Global consultancy specializing in digital transformation for large enterprises, offering strategy, creative, and technology solutions to drive business growth and success | IT Services and IT Consulting | 🇺🇸 St Louis | 4,362 |  |
| 27 | [Emerson Commercial & Residential Solutions](https://www.tamtam.ai/c/emerson-commercial-and-residential-solutions)<br>A company formerly known as Emerson Commercial and Residential Solutions now operates as Copeland, specializing in commercial and residential solutions | Appliances, Electrical, and Electronics Manufacturing | 🇺🇸 St. Louis | 4,189 |  |
| 28 | [Belden Inc.](https://www.tamtam.ai/c/belden-inc) (belden.com)<br>Connecting information and intelligence to simplify, secure, and enhance the digital journey for customers transforming the way the world works | Manufacturing | 🇺🇸 St. Louis | 4,091 | 1902 |
| 29 | [Pi Beta Phi Fraternity for Women](https://www.tamtam.ai/c/pi-beta-phi-fraternity-for-women) (pibetaphi.org)<br>An organization established in 1867, empowering women through a fraternity, foundation, and housing corporation, with over 300,000 members | Non-profit Organizations | 🇺🇸 Town and Country | 3,846 | 1867 |
| 30 | [Olin](https://www.tamtam.ai/c/olin) (olin.com)<br>Manufacturing and supplying chemical products with a focus on innovation, customer needs, ethical standards, and environmental stewardship worldwide. | Chemical Manufacturing | 🇺🇸 Clayton | 3,682 | 1892 |
| 31 | [Build-A-Bear Workshop](https://www.tamtam.ai/c/build-a-bear-workshop) (buildabear.com)<br>A beloved brand offering unique retail and entertainment experiences through customizable furry friend creations in over 400 worldwide locations | Retail | 🇺🇸 St. Louis | 3,522 | 1997 |
| 32 | [Sigma-Aldrich](https://www.tamtam.ai/c/sigma-aldrich) (bit.ly)<br>Providing scientists with lab materials, technologies, and services to simplify, accelerate, and improve life science research and biotech production worldwide. | Biotechnology Research | 🇺🇸 St. Louis | 3,467 | 1951 |
| 33 | [Enterprise Fleet Management](https://www.tamtam.ai/c/enterprise-fleet-management) (efleets.com)<br>A family-owned enterprise managing nearly a million vehicles in the US and Canada, offering fleet management services for businesses and organizations | Motor Vehicle Manufacturing | 🇺🇸 St. Louis | 3,409 | 1957 |
| 34 | [Webster University](https://www.tamtam.ai/c/webster-university) (webster.edu)<br>A global network of faculty, staff, students, and alumni focused on high-quality learning experiences for global citizenship and individual excellence | Higher Education | 🇺🇸 St. Louis | 3,249 | 1915 |
| 35 | [Whelan Security](https://www.tamtam.ai/c/whelan-security) (garda.com)<br>Industry-leading contract security company in the US, providing quality services to diverse clients and seeking talented individuals for security officer positions | Security and Investigations | 🇺🇸 St. Louis | 3,133 | 1949 |
| 36 | [Peabody Energy](https://www.tamtam.ai/c/peabody-energy) (peabodyenergy.com)<br>Leading coal producer supplying essential materials for affordable energy generation and steel manufacturing with a strong focus on sustainability. | Mining | 🇺🇸 St. Louis | 3,106 | 1883 |
| 37 | [JCI (Junior Chamber International)](https://www.tamtam.ai/c/jci-junior-chamber-international) (jci.cc)<br>Empowering young people worldwide through projects, events, training, and programs to develop leadership and community impact skills. | Non-profit Organizations | 🇺🇸 Chesterfield | 2,970 | 1915 |
| 38 | [Watlow](https://www.tamtam.ai/c/watlow) (watlow.com)<br>Global industrial technology company, expertise in thermal systems, providing temperature control, power control, heater technologies, and temperature sensing platforms to various industries. | Industrial Machinery Manufacturing | 🇺🇸 St. Louis | 2,840 | 1922 |
| 39 | [Rose International](https://www.tamtam.ai/c/rose-international) (roseint.com)<br>Provides staffing and total talent solutions across various industries, offering challenging assignments to skilled professionals for corporations and government agencies. | Staffing and Recruiting | 🇺🇸 Chesterfield | 2,270 | 1993 |
| 40 | [Veterans of Foreign Wars (VFW)](https://www.tamtam.ai/c/veterans-of-foreign-wars-vfw) (vfw.org)<br>A nonprofit veterans service organization dedicated to providing support, advocacy, and community service programs for eligible veterans and military service members worldwide | Civic and Social Organizations | 🇺🇸 Kansas City | 2,236 | 1899 |
| 41 | [Par Health](https://www.tamtam.ai/c/par-health) (parhealth.com)<br>Manufactures generic medicines, active pharmaceutical ingredients, and sterile injectables across multiple therapeutic areas, providing essential healthcare solutions for patients and providers. | Pharmaceutical Manufacturing | 🇺🇸 St Louis | 2,196 | 1978 |
| 42 | [MiTek](https://www.tamtam.ai/c/mitek) (mii.com)<br>Providing software, services, engineered products, and automated solutions to optimize integrated offsite construction for residential and commercial buildings. | Construction | 🇺🇸 Chesterfield | 2,171 |  |
| 43 | [CRB](https://www.tamtam.ai/c/crb) (crbgroup.com)<br>A leading provider of sustainable engineering, architecture, construction, and consulting solutions to global life sciences and food & beverage industries | Construction | 🇺🇸 Kansas City | 2,008 | 1984 |
| 44 | [American Century Investments](https://www.tamtam.ai/c/american-century-investments) (amcen.co)<br>Leading asset manager delivering investment results while funding medical research to improve health and support long-term client prosperity. | Financial Services | 🇺🇸 Kansas City | 1,900 | 1958 |
| 45 | [CTI](https://www.tamtam.ai/c/cti-st-louis) (cti.com)<br>CTI provides complete audio visual and information technology integration solutions, including design, installation, support, video conferencing, event services, and production | IT Services and IT Consulting | 🇺🇸 St. Louis | 1,887 | 1988 |
| 46 | [National Beef Packing Company LLC](https://www.tamtam.ai/c/national-beef-packing-company-llc) (nationalbeef.com)<br>Processing and marketing fresh beef, consumer-ready products, beef by-products, leather, and providing transportation and logistical services across multiple U.S. locations. | Food and Beverage Manufacturing | 🇺🇸 Kansas City | 1,757 | 1992 |
| 47 | [CFI](https://www.tamtam.ai/c/cfi) (cfidrive.com)<br>This company provides truckload, temperature-controlled, and Mexico services including LTL and TL trucking, transloading, consolidation, brokerage, and cross-border expertise #peopledrivepossibility | Truck Transportation | 🇺🇸 Joplin | 1,628 | 1951 |
| 48 | [International Brotherhood of Boilermakers](https://www.tamtam.ai/c/international-brotherhood-of-boilermakers) (boilermakers.org)<br>This company specializes in labor organization, focusing on advocating for and representing workers in various industries | Non-profit Organizations | 🇺🇸 Kansas City | 1,555 | 1880 |
| 49 | [Dent Wizard International](https://www.tamtam.ai/c/dent-wizard-international) (dentwizard.com)<br>Leader in automotive reconditioning services, providing paintless dent removal, paint repair, interior repair, and other services to automotive industry clients | Motor Vehicle Manufacturing | 🇺🇸 Bridgeton | 1,554 | 1983 |
| 50 | [Hunter Engineering Company](https://www.tamtam.ai/c/hunter-engineering-company) (hunter.com)<br>Global leader in automotive service equipment with innovative wheel alignment systems, balancers, tire changers, inspection equipment, brake lathes, and patented features for efficient undercar service | Motor Vehicle Manufacturing | 🇺🇸 Bridgeton | 1,535 | 1946 |

## How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 11, 2026.

## More company lists in Missouri

- [The largest companies in Missouri](https://www.tamtam.ai/l/largest-companies-missouri) (1,495)
- [Manufacturers in Missouri](https://www.tamtam.ai/l/manufacturers-missouri) (162)
- [Retail chains in Missouri](https://www.tamtam.ai/l/retail-chains-missouri) (143)
- [Education providers in Missouri](https://www.tamtam.ai/l/education-companies-missouri) (130)
- [Critical infrastructure operators in Missouri](https://www.tamtam.ai/l/critical-infrastructure-operators-missouri) (120)
- [Healthcare providers in Missouri](https://www.tamtam.ai/l/healthcare-providers-missouri) (118)
- [Hospitals and Health Care companies in Missouri](https://www.tamtam.ai/l/hospitals-and-health-care-companies-missouri) (118)
- [Financial services firms in Missouri](https://www.tamtam.ai/l/financial-services-firms-missouri) (116)
- [Companies with in-house R&D in Missouri](https://www.tamtam.ai/l/r-and-d-companies-missouri) (96)
- [Family-owned companies in Missouri](https://www.tamtam.ai/l/family-owned-companies-missouri) (84)
- [Professional services firms in Missouri](https://www.tamtam.ai/l/professional-services-firms-missouri) (84)
- [Companies with a mobile app in Missouri](https://www.tamtam.ai/l/companies-with-mobile-app-missouri) (78)
- [Public sector organisations in Missouri](https://www.tamtam.ai/l/public-sector-organisations-missouri) (78)
- [Construction companies in Missouri](https://www.tamtam.ai/l/construction-companies-missouri) (72)
- [Higher Education companies in Missouri](https://www.tamtam.ai/l/higher-education-companies-missouri) (70)
- [IT Services and IT Consulting companies in Missouri](https://www.tamtam.ai/l/it-services-and-it-consulting-companies-missouri) (69)
- [Hardware manufacturers in Missouri](https://www.tamtam.ai/l/hardware-companies-missouri) (68)
- [IT services companies in Missouri](https://www.tamtam.ai/l/it-services-companies-missouri) (61)
- [Corporate groups and holding companies in Missouri](https://www.tamtam.ai/l/holding-companies-missouri) (59)
- [Distributors and wholesalers in Missouri](https://www.tamtam.ai/l/distributors-and-wholesalers-missouri) (57)
- [Financial Services companies in Missouri](https://www.tamtam.ai/l/financial-services-companies-missouri) (53)
- [Logistics companies in Missouri](https://www.tamtam.ai/l/logistics-companies-missouri) (46)
- [Consulting firms in Missouri](https://www.tamtam.ai/l/consulting-firms-missouri) (43)
- [Contract manufacturers in Missouri](https://www.tamtam.ai/l/contract-manufacturers-missouri) (43)

## The same list elsewhere in United States

- [Multinational companies in the United States](https://www.tamtam.ai/l/multinational-companies-united-states) (16,197)
- [Multinational companies in California](https://www.tamtam.ai/l/multinational-companies-california) (2,592)
- [Multinational companies in New York State](https://www.tamtam.ai/l/multinational-companies-new-york-state) (2,216)
- [Multinational companies in Texas](https://www.tamtam.ai/l/multinational-companies-texas) (1,418)
- [Multinational companies in Florida](https://www.tamtam.ai/l/multinational-companies-florida) (897)
- [Multinational companies in Illinois](https://www.tamtam.ai/l/multinational-companies-illinois) (831)
- [Multinational companies in Massachusetts](https://www.tamtam.ai/l/multinational-companies-massachusetts) (637)
- [Multinational companies in New Jersey](https://www.tamtam.ai/l/multinational-companies-new-jersey) (624)
- [Multinational companies in Georgia](https://www.tamtam.ai/l/multinational-companies-georgia) (521)
- [Multinational companies in Pennsylvania](https://www.tamtam.ai/l/multinational-companies-pennsylvania) (472)
- [Multinational companies in Michigan](https://www.tamtam.ai/l/multinational-companies-michigan) (468)
- [Multinational companies in Alabama](https://www.tamtam.ai/l/multinational-companies-alabama) (416)
- [Multinational companies in Virginia](https://www.tamtam.ai/l/multinational-companies-virginia) (396)
- [Multinational companies in Ohio](https://www.tamtam.ai/l/multinational-companies-ohio) (390)
- [Multinational companies in North Carolina](https://www.tamtam.ai/l/multinational-companies-north-carolina) (358)
- [Multinational companies in Washington State](https://www.tamtam.ai/l/multinational-companies-washington-state) (288)
- [Multinational companies in Colorado](https://www.tamtam.ai/l/multinational-companies-colorado) (228)
- [Multinational companies in New York](https://www.tamtam.ai/l/multinational-companies-new-york) (1,836)
- [Multinational companies in San Francisco](https://www.tamtam.ai/l/multinational-companies-san-francisco) (446)
- [Multinational companies in Houston](https://www.tamtam.ai/l/multinational-companies-houston) (402)
- [Multinational companies in Chicago](https://www.tamtam.ai/l/multinational-companies-chicago) (366)
- [Multinational companies in Miami](https://www.tamtam.ai/l/multinational-companies-miami) (289)
- [Multinational companies in Atlanta](https://www.tamtam.ai/l/multinational-companies-atlanta) (252)
- [Multinational companies in Boston](https://www.tamtam.ai/l/multinational-companies-boston) (241)

---

Source: https://www.tamtam.ai/l/multinational-companies-missouri