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The 32 largest Non-profit Organizations companies in South Africa

Tamtam tracks 32 Non-profit Organizations companies headquartered in South Africa. This list ranks all of them by number of employees on LinkedIn, led by Home Group, Anova Health Institute and Youth Employment Service (YES) South Africa. Their median headcount is 396. Half of them were founded in 2001 or later. The most common headquarters are Cape Town (11) and Johannesburg (11).

馃嚳馃嚘 South Africa32 companiesUpdated Oct 10, 2026
#CompanyIndustryHeadquarters EmployeesFounded
1
Home Grouphomegroup.org.uk

providing high quality housing and integrated health and social care services to over 125,000 customers across UK

Non-profit Organizations 馃嚳馃嚘 8,229 1935
2
Anova Health Instituteanovahealth.co.za

An NGO empowering communities through healthcare solutions, research, and support, with a focus on HIV, men's health, key populations, and medical expertise

Non-profit Organizations 馃嚳馃嚘 Parktown North 2,153 2008
3
Youth Employment Service (YES) South Africayes4youth.co.za

Empowering youth by providing economic opportunities and building a future that fosters dignity and success for individuals and communities

Non-profit Organizations 馃嚳馃嚘 Johannesburg 2,058 2017
4
Afrika Tikkunafrikatikkun.org

Non-profit organization empowering vulnerable children in townships through holistic programs and support services to eradicate poverty and enable career success

Non-profit Organizations 馃嚳馃嚘 Johannesburg 1,632 1994
5
TB HIV Caretbhivcare.org

Non-profit organization improving TB management through increased access to diagnosis, treatment, care, and community-based adherence support for TB & HIV clients

Non-profit Organizations 馃嚳馃嚘 Cape Town 1,261 1929
6
sisalesians.org.za

Provides skills training, education, and development for vulnerable children and youth in Greater Cape Town, including job placements and impact evaluations Collaborates with partners for enhanced outcomes

Non-profit Organizations 馃嚳馃嚘 Kouga 1,228 1910
7
Health Systems Trusthst.org.za

not-for-profit organization supporting equitable and efficient primary health care system development and transformation in southern Africa since 1992

Non-profit Organizations 馃嚳馃嚘 1,024 1992
8
loveLifelovelife.org.za

loveLife promotes healthy, positive, HIV-free living among South African teenagers through multi-media campaigns, community outreach, and youth volunteer programs

Non-profit Organizations 馃嚳馃嚘 Johannesburg 1,017 1999
9
African Parks Networkafricanparks.org

Non-profit organization managing protected areas across Africa in partnership with governments and local communities for conservation and sustainability.

Non-profit Organizations 馃嚳馃嚘 Bryanston 786 2000
10
Allan Gray Orbis Foundationallangrayorbis.org

An organization that invests in developing high-impact responsible entrepreneurs through scholarships and fellowships for the youth in Southern Africa

Non-profit Organizations 馃嚳馃嚘 Cape Town 762 2005
11
Mr Price Foundationmrpricefoundation.org

A youth development organization empowering young people through education and skills training to break the cycle of poverty and inequality

Non-profit Organizations 馃嚳馃嚘 Durban 618 2005
12
Seriti Institute (NPC)seriti.org.za

Development facilitation agency providing technical support, project management, and facilitated learning to enhance socioeconomic impact and promote civic-driven change and accountability

Non-profit Organizations 馃嚳馃嚘 Midrand 599 2009
13
mothers2mothersm2m.org

An Africa-based organization employing women living with HIV to provide health education and services, aiming to end pediatric AIDS and create healthy communities

Non-profit Organizations 馃嚳馃嚘 Cape Town 512 2001
14
Doctors Without Borders (MSF) Southern Africamsf.org.za

An international medical humanitarian organization providing unbiased medical assistance to people affected by crises and advocating for their needs

Non-profit Organizations 馃嚳馃嚘 Johannesburg 416 1971
15
Desmond Tutu Health Foundationdesmondtutuhealthfoundation.org.za

A research center in South Africa focusing on HIV and related infections, dedicated to excellence in research, treatment, training, and prevention

Non-profit Organizations 馃嚳馃嚘 Cape Town 413 2004
16
Khethimpilokhethimpilo.org

Specializing in health and community systems strengthening, we provide comprehensive solutions for HIV, TB, community adherence, ECD, school health, and training

Non-profit Organizations 馃嚳馃嚘 Cape Town 396 2009
17
ForAfrikaforafrika.org

African aid organization combating hunger through nutrition, water and sanitation, health programs, education, and economic development to empower communities for self-sustainability

Non-profit Organizations 馃嚳馃嚘 Johannesburg 387 1984
18
NICROnicro.org.za

Promoting personal responsibility, restorative justice, and community development to create a safer South Africa through victim empowerment and offender rehabilitation

Non-profit Organizations 馃嚳馃嚘 Cape Town 372 1910
19
Wild Impactwildimpact.earth

A non-profit organization empowering rural communities near conservation areas through partnerships with eco-tourism operators, focusing on community participation and local leadership

Non-profit Organizations 馃嚳馃嚘 Johannesburg 355 1992
20
Living Hopelivinghope.co.za

Faith-based non-profit organization tackling poverty, disease, and despair through community development initiatives aligned with 12 UN Sustainable Development Goals

Non-profit Organizations 馃嚳馃嚘 Cape Town 336 2000
21
African Leadership Academyafricanleadershipacademy.org

Transforming Africa by identifying, developing, and connecting future ethical leaders through a diverse community of global change makers

Non-profit Organizations 馃嚳馃嚘 Johannesburg 325 2008
22
Community Media Trustcmt.org.za

A non-profit organization specializing in media production and communication services focused on health, human rights, and social behavior change in South Africa

Non-profit Organizations 馃嚳馃嚘 Cape Town 284 1998
23
Umuzi.orgumuzi.org

Empowering young people through innovative, hands-on education in digital and creative fields, helping them secure top jobs and reach career goals

Non-profit Organizations 馃嚳馃嚘 Johannesburg 255 2009
24
Africa's Young Entrepreneurs Organizationayeorganization.com

Empowering young entrepreneurs in Africa through networking, conferences, and resources to drive business success, social entrepreneurship, and economic development

Non-profit Organizations 馃嚳馃嚘 Randburg 182 2012
25
Khulisa Social Solutionskhulisa.org.za

A national non-profit inspiring vulnerable children and communities to unlock their potential and find resilience through empowerment and skills development

Non-profit Organizations 馃嚳馃嚘 Johannesburg 172 1997
26
Violence Prevention through Urban Upgrading (VPUU NPC)vpuu.org.za

Area-based community organization focusing on safe, sustainable neighborhoods Utilizes participatory approach to improve safety, social cohesion, and quality of life through urban improvements and social interventions

Non-profit Organizations 馃嚳馃嚘 Cape Town 167 2005
27
Funda Wandefundawande.org

A non-profit organization in South Africa focused on improving literacy and numeracy skills in learners by age 10 through teacher training materials

Non-profit Organizations 馃嚳馃嚘 Cape Town 160 2017
28
Youth Health Africayhafrica.org

A healthcare-focused youth empowerment organization in Africa combating HIV and youth unemployment through skills development, prevention programs, and digital media campaigns

Non-profit Organizations 馃嚳馃嚘 Johannesburg 155 2018
29
Black Management Forumbmfonline.co.za

Providing workshops, conferences, and programs to develop leadership skills while advocating for socio-economic transformation and legislative change in South Africa.

Non-profit Organizations 馃嚳馃嚘 Johannesburg 147 1976
30
Ikamva Labantuikamva.org.za

A non-profit organization in Cape Town's townships, dedicated to sustainable development and holistic community support for children and older persons

Non-profit Organizations 馃嚳馃嚘 Cape Town 99 1963
31
SAVERSvolunteer.org.za

The company aims to foster a better future for children through volunteer opportunities, donations, community support, and programs to meet their needs

Non-profit Organizations 馃嚳馃嚘 Bellville 16 2021
32
HEARTLAND SA (NPC)heartland.org.za

Heartland is dedicated to restoring masculinity to the Body of Christ through Christ-centered events and teachings on true godly masculinity

Non-profit Organizations 馃嚳馃嚘 Outer West Durban 2 2009

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How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Oct 10, 2026.

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