These companies with in-house R&D in Colombia are mostly large, established organizations in various sectors. The list includes major players in the energy, food, pharmaceutical, and healthcare industries. Ecopetrol, the largest by employees, is Colombia's main energy group. Alpina is a 78-year-old brand in food manufacturing, while TQ (Tecnoquímicas) leads in pharmaceuticals.
A significant number of institutions are in higher education, such as Universidad Tecnológica de Pereira and Universidad Externado de Colombia. Fundacion Valle del Lili is a leading hospital. The data shows a concentration of companies in Bogotá and Cali, with a strong presence of universities across different cities.
| # | Company | Employees | |||
|---|---|---|---|---|---|
| 1 |
Ecopetrolecopetrol.com.co
Largest Colombian energy group with integrated operations in hydrocarbons, gas, power, and infrastructure, focusing on diversification and decarbonization through renewables and technology. |
12,994 | |||
| 2 |
Alpinaalpina.com
A 78-year-old brand in Colombia that offers high nutritional value products with top quality standards and delicious flavors, focusing on sustainability and innovation |
8,901 | |||
| 3 |
TQ (Tecnoquímicas)tqconfiable.com
Leader in pharmaceutical and mass-market products, offering a wide range of reliable brands with a focus on health and wealth worldwide |
4,359 | |||
| 4 |
Fundación Valle del Lilivalledellili.org
A leading high-complexity hospital with over 40 years of history, 774 highly qualified doctors, all specialties, and top rankings nationally and internationally |
3,318 | |||
| 5 |
Universidad Tecnológica de Pereirautp.edu.co
A leading Colombian public university offering undergraduate and graduate programs across various faculties, with a diverse student body and flexible class schedules |
3,140 | |||
| 6 |
Universidad Externado de Colombiauexternado.edu.co
Higher education institution focused on social sciences, promoting pluralism, tolerance, national identity, democracy, and integral student formation. |
3,125 | |||
| 7 |
Organizacion Coronaempresa.corona.co
A Colombian multinational with over 140 years of history manufacturing and selling products for home, construction, industry, agriculture, and energy sectors globally |
3,112 | |||
| 8 |
Universidad del Caucaunicauca.edu.co
A 180-year-old national public higher education institution in Colombia, offering undergraduate and graduate programs in a peaceful environment in Popayán |
2,678 | |||
| 9 |
Universidad Icesiicesi.edu.co
A prestigious university in Cali, Colombia offering a wide range of undergraduate and graduate programs, with strong ties to businesses and a commitment to excellence |
2,625 | |||
| 10 |
Fundacion Santa Fe de Bogotafundacionsantafedebogota.com
A non-profit organization focusing on developing and implementing high-impact health management models, promoting healthy environments in vulnerable communities, and ensuring corporate social responsibility |
2,621 | |||
| 11 |
Universidad del Atlánticouniatlantico.edu.co
Leading higher education institution in the Caribbean region of Colombia with approximately 25,000 students, currently on the path to institutional accreditation |
2,262 | |||
| 12 |
Pontificia Universidad Javeriana Calijaverianacali.edu.co
A prestigious educational institution with nearly 400 years of history, offering undergraduate and postgraduate programs, as well as continuing education courses |
2,219 | |||
| 13 |
Universidad Autónoma de Occidenteuao.edu.co
Higher Education institution in Cali, Colombia, offering undergraduate and graduate programs in Engineering, Economics, Communication, Sciences, and Humanities with a focus on research |
2,011 | |||
| 14 |
Instituto Geográfico Agustín Codazzi (IGAC)igac.gov.co
The organization is responsible for producing official maps and basic cartography, conducting national real estate surveys, soil inventories, geographical research, and coordinating spatial data |
2,008 | |||
| 15 |
Organización Clínica General del Norteclinicageneraldelnorte.com
A healthcare institution with 50 years of experience, advanced medical technology, 24hr emergency services, and a commitment to excellence in patient care |
1,919 | |||
| 16 |
Clínica FOSCALfoscal.com.co
A medical complex founded in 1993 with the support of Dr Carlos Ardila Lülle, offering specialized healthcare services with a focus on quality and patient-centered care |
1,895 | |||
| 17 |
Universidad Central (CO)ucentral.edu.co
An institution of higher education, in compliance with Ministry of National Education regulations, with internal organization based on its General Statute |
1,806 | |||
| 18 |
Universidad de la Costa CUCcuc.edu.co
A higher education institution that has trained over 30,000 professionals, focusing on academic excellence, research, and fostering critical thinking and pluralism |
1,763 | |||
| 19 |
Fundación Cardiovascular de Colombiafcv.org
FCV is a national and international health ecosystem offering high-quality medical services and innovation, aiming to provide personalized, comprehensive care to improve lives |
1,641 | |||
| 20 |
AGROSAVIA - Corporación colombiana de investigación agropecuariaagrosavia.co
A Colombian entity focused on agrarian research, driving technical advancements to enhance productivity and competitiveness in the agricultural sector |
1,583 | |||
| 21 |
Universidad Simón Bolívarunisimon.edu.co
A non-profit private university in Barranquilla, Colombia known for academic excellence, promoting social development based on the ideals of the liberator |
1,523 | |||
| 22 |
Universidad Autonoma de Manizalesautonoma.edu.co
The organization is an educational community focused on promoting knowledge, ethical entrepreneurship, and critical thinking through diverse postgraduate programs in various fields |
1,442 | |||
| 23 |
Fundación Universitaria Los Libertadoresulibertadores.edu.co
An non-profit higher education institution inspired by the values of freedom, order, and justice, based on the ideals of national heroes |
1,400 | |||
| 24 |
Hospital Pablo Tobón Uribehptu.org
Committed to quality and safety in services since 1970, leading in excellence with awards for family-friendly practices and top rankings in Latin America |
1,377 | |||
| 25 |
CIATciat.cgiar.org
The organization specializes in providing research-based solutions that utilize agricultural biodiversity to enhance food systems and benefit communities amidst a climate crisis |
1,351 | |||
Want more companies than this list?This page shows the largest ones only. Connect to Tamtam to see every company that matches, filter by size, industry or growth, and reach their decision-makers. | |||||
| 26 |
Universidad de Santanderudes.edu.co
A private non-profit university in Colombia, founded in 1982, offering a wide range of academic programs in various fields across multiple cities |
1,312 | |||
| 27 |
Veolia Colombialatinoamerica.veolia.com
Global leader designing water, waste, and energy solutions for communities and industries to improve resource access while protecting and renewing environmental resources. |
1,294 | |||
| 28 |
Universidad FUCSfucsalud.edu.co
An institution of higher education focused on comprehensive student development in health sciences through research, technology, and social impact for community well-being |
1,264 | |||
| 29 |
Escuela Colombiana de Ingeniería Julio Garavitoescuelaing.edu.co
A university in Colombia focusing on integral education, knowledge building, and societal development with relevance to Colombian reality |
1,186 | |||
| 30 |
Elite Flowereliteflower.com
Specializing in growing and breeding roses, Alstroemerias, and Gerberas with a focus on sustainability, social responsibility, and environmental awareness |
1,181 | |||
| 31 |
Fundación Clínica Shaioshaio.org
A leading institution in high complexity cardiovascular care with over 60 years of experience, ensuring quality and safety through cutting-edge technology and innovation |
1,155 | |||
| 32 |
COTECMARcotecmar.com
Innovative organization specializing in advanced design, construction, repair, and maintenance of custom naval platforms for the Colombian maritime industry |
1,117 | |||
| 33 |
Universidad Autónoma del Caribeuac.edu.co
A center of culture and science focused on generating, validating, and applying knowledge across various areas of learning, fostering academic excellence and societal solutions |
1,111 | |||
| 34 |
Universidad de Boyacáuniboyaca.edu.co
Higher education institution offering undergraduate, postgraduate, master's, diplomas, and seminars in various faculties such as engineering, architecture, law, and health sciences |
1,110 | |||
| 35 |
Darnel Groupdarnelgroup.com
A global leader in plastic packaging and disposables, offering a diverse range of products and operating in over 20 countries worldwide |
1,075 | |||
| 36 |
Solla S.A.solla.com
Production and commercialization of balanced animal feed, supporting economically successful livestock farming with quality products and services since 1948. |
1,063 | |||
| 37 |
Unidades Tecnológicas de Santanderuts.edu.co
A public institution in Santander focused on ethical education, critical thinking, and entrepreneurship through quality teaching, research, and outreach for societal development |
1,038 | |||
| 38 |
Applus+ América Latinaapplus.com
Applus+ offers comprehensive project management, technical assistance, inspection, and testing solutions with a focus on ethics, customer orientation, and safety |
1,006 | |||
| 39 |
Institución Universitaria - Tecnológico de Antioquiatdea.edu.co
The institution offers a public university education with high-quality academic programs in a campus with extensive facilities and green areas |
987 | |||
| 40 |
Alianza Team®alianzateam.com
A multinational with over 7 decades in the vegetable oils industry, operating in Colombia, Chile, Mexico, and the US, focusing on lipid-based products and solutions |
953 | |||
| 41 |
Prebel S.Aprebel.com
With over 80 years of experience, this company manufactures and sells cosmetic and personal care products globally, focusing on customer satisfaction and employee well-being |
949 | |||
| 42 |
Universidad Marianaumariana.edu.co
An educational institution located in Nariño, Colombia, offering primary and secondary level education programs |
903 | |||
| 43 |
Universidad de Ibaguéunibague.edu.co
A university offering ten high-quality accredited programs, dedicated to supporting regional development in Ibagué |
838 | |||
| 44 |
Genfargenfar.com
Established in 1967 in Colombia, this organization is dedicated to manufacturing and providing affordable medications to enhance healthcare access in Latin America |
776 | |||
| 45 |
Universidad de San Buenaventurausbmed.edu.co
This page provides all information about Universidad de San Buenaventura Medellín, serving as a comprehensive resource for the institution |
747 | |||
| 46 |
Lockheed Martin Rotary & Mission Systemslockheedmartin.com
Specializes in a diverse portfolio of programs including defense, warfare, radar, cyber solutions, and training systems for various military and international customers Employing over 35,000 professionals globally |
740 | |||
| 47 |
Clínica Universidad de La Sabanaclinicaunisabana.edu.co
A high-complexity Health Academic Center dedicated to providing healthcare, training individuals, and conducting biomedical research |
738 | |||
| 48 |
Fundación Universitaria Konrad Lorenzkonradlorenz.edu.co
A higher education institution in Bogotá, Colombia, dedicated to teaching, research, and cultural diffusion in various fields like mathematics, engineering, marketing, and psychology |
651 | |||
| 49 |
Coaspharmacoaspharma.com.co
Colombian company specialized in developing, manufacturing, and selling pharmaceutical and cosmetic products for both human and veterinary use, following good practices |
619 | |||
| 50 | 616 | ||||
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Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 12, 2026.
More company lists in Colombia
- The largest companies in Colombia 2,285
- Multinational companies in Colombia 311
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- Higher Education companies in Colombia 138
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- Companies with a mobile app in Colombia 105
- Government Administration companies in Colombia 101
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- Logistics companies in Colombia 71
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