# The 30 largest companies with in-house R&D in the Doubs department

Tamtam tracks 78 companies with in-house R&D headquartered in the Doubs department. This list ranks the 30 largest by number of employees on LinkedIn, led by CHU de Besançon, DELFINGEN and Amphenol FCi. Their median headcount is 128. Half of them were founded in 1967 or later. The most common headquarters are Besançon (12).

This list features companies in the Doubs department that conduct in-house research and development. The selection includes a mix of established industrial firms and specialized manufacturers. Notable examples include DELFINGEN, a global automotive supplier for on-board networks, and Amphenol FCi, which designs and manufactures connectors for various electronics sectors. Peugeot Motocycles Groupe is also present, known for its two and three-wheeled vehicles.

The companies demonstrate a strong presence in the automotive sector, with several firms like Flex-N-Gate Europe and Schrader Pacific Advanced Valves focusing on motor vehicle parts and manufacturing. There is also a significant representation of precision manufacturing and industrial machinery, such as R.Bourgeois, producing magnetic steel laminations, and STREIT Groupe, a machining and assembly specialist.

🇫🇷 Doubs · 30 companies · Updated Nov 11, 2026

| # | Company | Industry | Headquarters | Employees | Founded |
|---|---|---|---|---|---|
| 1 | [CHU de Besançon](https://www.tamtam.ai/c/chu-de-besancon) (chu-besancon.fr)<br>The organization provides specialized healthcare services, conducts research, offers training for healthcare professionals, and collaborates with regional establishments in Besançon | Hospitals and Health Care | 🇫🇷 Besançon | 1,602 |  |
| 2 | [DELFINGEN](https://www.tamtam.ai/c/delfingen) (delfingen.com)<br>Global automotive supplier specializing in on-board networks protection solutions and fluid transfer tubing, with a focus on customer satisfaction and worldwide presence since 1954 | Motor Vehicle Parts Manufacturing | 🇫🇷 Anteuil | 1,440 | 1954 |
| 3 | [Amphenol FCi](https://www.tamtam.ai/c/amphenol-fci) (amphenol-fci-besancon.com)<br>Design and manufacture high-quality connectors in telecommunications, consumer electronics, data storage, industry, and automotive sectors with full in-house production. | Computers and Electronics Manufacturing | 🇫🇷 Besançon | 1,097 | 1981 |
| 4 | [Flex-N-Gate Europe](https://www.tamtam.ai/c/flex-n-gate-europe) (flex-n-gate.com)<br>Manufacturing and supplying high-quality automotive external parts including plastic, metal, assembly, and lighting with extensive R&D and production facilities. | Motor Vehicle Manufacturing | 🇫🇷 Audincourt | 457 |  |
| 5 | [Peugeot Motocycles Groupe](https://www.tamtam.ai/c/peugeot-motocycles-groupe) (peugeot-motocycles.com)<br>Designs and sells two and three-wheeled motorcycles, including premium French models, electric motorcycles, and historic brands, with a global network. | Motor Vehicle Manufacturing | 🇫🇷 Mandeure | 355 | 1898 |
| 6 | [SIS Manufacture de Maroquinerie](https://www.tamtam.ai/c/sis-manufacture-de-maroquinerie) (sis-fr.com)<br>Development, industrialization, and production of leather goods, leather wrapping, and watch straps with tradition and innovation. | Retail Luxury Goods and Jewelry | 🇫🇷 Valdahon | 332 | 1998 |
| 7 | [SOTTAS SA](https://www.tamtam.ai/c/sottas-sa) (sottas.ch)<br>Swiss company specializing in metal construction projects including industrial buildings, administrative centers, commercial spaces, bridges, and various metal structures with 300 employees. | Construction | 🇫🇷 Bulle | 289 | 1982 |
| 8 | [Zurflüh-Feller](https://www.tamtam.ai/c/zurfluh-feller) (zurfluh-feller.fr)<br>Design, development, and manufacturing of exterior building closure components with extensive industrial integration and international market presence. | Building Finishing Contractors | 🇫🇷 Noirefontaine | 255 | 1920 |
| 9 | [Schrader Pacific Advanced Valves](https://www.tamtam.ai/c/schrader-pacific-advanced-valves) (schrader-pacific.fr)<br>Designs and produces valves and components for automotive, industrial, and aeronautical sectors, focusing on innovative solutions for future mobility challenges. | Motor Vehicle Parts Manufacturing | 🇫🇷 Pontarlier | 219 | 1898 |
| 10 | [STREIT Groupe](https://www.tamtam.ai/c/streit-groupe) (linktr.ee)<br>A machining, assembly, and co-design specialist with a focus on high-quality global solutions, offering turn-key solutions and a range of services | Industrial Machinery Manufacturing | 🇫🇷 Pays-de-Clerval | 205 | 1968 |
| 11 | [GUILLIN EMBALLAGES](https://www.tamtam.ai/c/guillin-emballages) (groupeguillin.fr)<br>Design, manufacture, and distribute standard thermoformed plastic packaging for food industry professionals across Europe, focusing on cakes and catering. | Packaging and Containers Manufacturing | 🇫🇷 Ornans | 184 | 1972 |
| 12 | [R.Bourgeois](https://www.tamtam.ai/c/r-bourgeois) (rbourgeois.fr)<br>Production and supply of high precision magnetic steel rotor and stator lamination assemblies for electric motors, generators, and transformers worldwide. | Industrial Machinery Manufacturing | 🇫🇷 Besançon | 176 | 1929 |
| 13 | [PEUGEOT SAVEURS SNC](https://www.tamtam.ai/c/peugeot-saveurs-snc) (fr.peugeot-saveurs.com)<br>Design and production of spice and coffee mills, wine accessories, ceramic ovenware, and offering exceptional spices with sustainable practices. | Manufacturing | 🇫🇷 Quingey | 133 | 1810 |
| 14 | [MANTION](https://www.tamtam.ai/c/mantion) (mantion.com)<br>Design, manufacture, and distribution of sliding systems for doors, gates, and shutters serving residential and industrial construction markets worldwide. | Wholesale Building Materials | 🇫🇷 Besançon | 131 | 1920 |
| 15 | [JTEKT COLUMN SYSTEMS FRANCE](https://www.tamtam.ai/c/jtekt-column-systems-france) (jtekt-cs.fr)<br>An automotive supplier specializing in steering columns with 400 employees, part of the global FUJIKIKO Group based in Japan Recruiting in various sectors Visit website | Motor Vehicle Parts Manufacturing | 🇫🇷 Mandeure | 128 | 2023 |
| 16 | [MARCEAU](https://www.tamtam.ai/c/marceau) (marceau.fr)<br>Design and manufacture of robust continuous handling systems for internal logistics, optimizing processes with automation in various industrial sectors. | Machinery Manufacturing | 🇫🇷 Doubs | 99 | 1946 |
| 17 | [Micro-Mega SA](https://www.tamtam.ai/c/micro-mega-sa) (micro-mega.com)<br>A globally recognized company specializing in designing, manufacturing, and selling high-quality dental surgery devices since 1905, with a focus on endodontic products made in France | Medical Equipment Manufacturing | 🇫🇷 Besançon | 98 | 1905 |
| 18 | [Statice](https://www.tamtam.ai/c/statice) (statice.com)<br>Design, development, and production of customized medical implants and instruments using advanced microtechniques and biomaterials for various specialties. | Biotechnology Research | 🇫🇷 Besançon | 94 | 1978 |
| 19 | [AUGE MICROTECHNIC GROUP](https://www.tamtam.ai/c/auge-microtechnic-group) (augemicrotechnic.com)<br>Specializes in development, tooling, cutting, slitting, injection molding and overmolding, stamping, and assembly of microtechnic components. | Manufacturing | 🇫🇷 Thise | 89 | 1934 |
| 20 | [SOPIL](https://www.tamtam.ai/c/sopil) (sopil.fr)<br>Family-owned company specializing in stamping small ferrous and alloy metal parts for automotive, electrical, aerospace, medical, and household appliance industries. | Appliances, Electrical, and Electronics Manufacturing | 🇫🇷 Pirey | 81 | 1961 |
| 21 | [ALCIS](https://www.tamtam.ai/c/alcis) (alcis.net)<br>Expertise and equipment for developing, certifying, and manufacturing EC-marked medical devices, including quality management and legal manufacturing roles. | Biotechnology Research | 🇫🇷 Besançon | 77 | 1999 |
| 22 | [SIMONIN WOOD SOLUTIONS](https://www.tamtam.ai/c/simonin-wood-solutions) (simonin.com)<br>Manufacture and export of high-quality, customized wood construction components with advanced technology and extensive international experience since 1967. | Construction | 🇫🇷 Montlebon | 72 | 1967 |
| 23 | [CRYLA GROUP](https://www.tamtam.ai/c/cryla-group) (cryla-group.com)<br>Cryla Group specializes in high-precision microtechnical subcontracting, industrializing innovative solutions for demanding markets such as Aerospace, Medical, Luxury, and Industry | Industrial Machinery Manufacturing | 🇫🇷 Besançon | 70 | 1951 |
| 24 | [Alliance MIM](https://www.tamtam.ai/c/alliance-mim) (alliance-mim.com)<br>Design and manufacture of innovative technological solutions using metal and ceramic powder injection and sintering for high-value small technical assemblies. | Industrial Machinery Manufacturing | 🇫🇷 Saint-Vit | 68 | 1995 |
| 25 | [GROUPE MAILLARD INDUSTRIE](https://www.tamtam.ai/c/groupe-maillard-industrie) (groupgmi.com)<br>Specialized industrial group in plastic and metal transformation, offering custom solutions across diverse sectors with innovation and expertise. | Manufacturing | 🇫🇷 Autechaux | 67 | 1981 |
| 26 | [RD-BIOTECH](https://www.tamtam.ai/c/rd-biotech) (rd-biotech.com)<br>French CRO specializing in biomanufacturing of plasmids, monoclonal antibodies, recombinant proteins, and cells Services include antibody engineering, analytical services, and FastELISA kits development | Biotechnology Research | 🇫🇷 Besançon | 67 | 2002 |
| 27 | [DIXI microtechniques](https://www.tamtam.ai/c/dixi-microtechniques) (diximicrotechniques.com)<br>Manufacturing high-precision microtechnology components and solutions for various industries, focusing on quality and advanced engineering techniques. | Industrial Machinery Manufacturing | 🇫🇷 Marchaux-Chaudefontaine | 65 |  |
| 28 | [Pixee Medical](https://www.tamtam.ai/c/pixee-medical) (pixee-medical.com)<br>Development of augmented reality smart glasses and software for precise, consumable-free surgical navigation and prosthesis placement assistance. | Medical Equipment Manufacturing | 🇫🇷 Besançon | 65 | 2017 |
| 29 | [Digital Surf](https://www.tamtam.ai/c/digital-surf) (digitalsurf.com)<br>Provider of innovative micro and nano-surface metrology solutions with flagship Mountains Technology software for research, industrial, and production environments. | Software Development | 🇫🇷 Besançon | 61 | 1989 |
| 30 | [FRALSEN](https://www.tamtam.ai/c/fralsen) (fralsen.fr)<br>A precision microtechnical parts manufacturer serving high-tech industries like defense, medical, and space with expertise in design, R&D, and assembly | Primary Metal Manufacturing | 🇫🇷 Besançon | 53 | 1962 |

## How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 11, 2026.

## More company lists in the Doubs department

- [The largest companies in the Doubs department](https://www.tamtam.ai/l/largest-companies-doubs) (406)
- [Contract manufacturers in the Doubs department](https://www.tamtam.ai/l/contract-manufacturers-doubs) (56)
- [Manufacturers in the Doubs department](https://www.tamtam.ai/l/manufacturers-doubs) (54)
- [Multinational companies in the Doubs department](https://www.tamtam.ai/l/multinational-companies-doubs) (49)
- [Retail chains in the Doubs department](https://www.tamtam.ai/l/retail-chains-doubs) (32)
- [Public sector organisations in the Doubs department](https://www.tamtam.ai/l/public-sector-organisations-doubs) (31)
- [Hardware manufacturers in the Doubs department](https://www.tamtam.ai/l/hardware-companies-doubs) (27)
- [Family-owned companies in the Doubs department](https://www.tamtam.ai/l/family-owned-companies-doubs) (27)

## The same list elsewhere in France

- [Companies with in-house R&D in France](https://www.tamtam.ai/l/r-and-d-companies-france) (8,750)
- [Companies with in-house R&D in Île-de-France](https://www.tamtam.ai/l/r-and-d-companies-ile-de-france) (2,695)
- [Companies with in-house R&D in Auvergne-Rhône-Alpes](https://www.tamtam.ai/l/r-and-d-companies-auvergne-rhone-alpes) (1,460)
- [Companies with in-house R&D in Occitanie](https://www.tamtam.ai/l/r-and-d-companies-occitanie) (680)
- [Companies with in-house R&D in Grand Est](https://www.tamtam.ai/l/r-and-d-companies-grand-est) (640)
- [Companies with in-house R&D in Provence-Alpes-Côte d'Azur](https://www.tamtam.ai/l/r-and-d-companies-provence-alpes-cote-dazur) (613)
- [Companies with in-house R&D in Nouvelle-Aquitaine](https://www.tamtam.ai/l/r-and-d-companies-nouvelle-aquitaine) (566)
- [Companies with in-house R&D in the Hauts-de-Seine department](https://www.tamtam.ai/l/r-and-d-companies-hauts-de-seine) (510)
- [Companies with in-house R&D in the Rhône department](https://www.tamtam.ai/l/r-and-d-companies-rhone) (509)
- [Companies with in-house R&D in Pays de la Loire](https://www.tamtam.ai/l/r-and-d-companies-pays-de-la-loire) (480)
- [Companies with in-house R&D in Hauts-de-France](https://www.tamtam.ai/l/r-and-d-companies-hauts-de-france) (410)
- [Companies with in-house R&D in Brittany](https://www.tamtam.ai/l/r-and-d-companies-brittany) (366)
- [Companies with in-house R&D in the Haute-Garonne department](https://www.tamtam.ai/l/r-and-d-companies-haute-garonne) (323)
- [Companies with in-house R&D in the Bouches-du-Rhône department](https://www.tamtam.ai/l/r-and-d-companies-bouches-du-rhone) (321)
- [Companies with in-house R&D in the Isère department](https://www.tamtam.ai/l/r-and-d-companies-isere) (304)
- [Companies with in-house R&D in Bourgogne-Franche-Comté](https://www.tamtam.ai/l/r-and-d-companies-bourgogne-franche-comte) (261)
- [Companies with in-house R&D in the Nord department](https://www.tamtam.ai/l/r-and-d-companies-nord) (237)
- [Companies with in-house R&D in Normandy](https://www.tamtam.ai/l/r-and-d-companies-normandy) (227)
- [Companies with in-house R&D in the Gironde department](https://www.tamtam.ai/l/r-and-d-companies-gironde) (225)
- [Companies with in-house R&D in the Loire-Atlantique department](https://www.tamtam.ai/l/r-and-d-companies-loire-atlantique) (207)
- [Companies with in-house R&D in the Essonne department](https://www.tamtam.ai/l/r-and-d-companies-essonne) (198)
- [Companies with in-house R&D in Centre-Val de Loire](https://www.tamtam.ai/l/r-and-d-companies-centre-val-de-loire) (195)
- [Companies with in-house R&D in Paris](https://www.tamtam.ai/l/r-and-d-companies-paris) (1,249)
- [Companies with in-house R&D in Lyon](https://www.tamtam.ai/l/r-and-d-companies-lyon) (192)

---

Source: https://www.tamtam.ai/l/r-and-d-companies-doubs
