# Top 30 companies with in-house R&D in the Drôme department

Tamtam tracks 59 companies with in-house R&D headquartered in the Drôme department. This list ranks the 30 largest by number of employees on LinkedIn, led by HM.CLAUSE, Crouzet and COP Chimie. Their median headcount is 107. Half of them were founded in 1982 or later. The most common headquarters are Romans-sur-Isère (4) and Valence (4).

These companies in Drôme are primarily mid-sized firms, many with a long history, specializing in industrial manufacturing, particularly in sectors like construction, aerospace, and medical equipment. They often focus on niche markets and advanced technologies. For example, Crouzet manufactures mechatronic components for aerospace, while AMPLITUDE develops orthopedic surgical products.

A common pattern among these companies is their geographical concentration around Valence and Bourg-lès-Valence. COP Chimie produces high-performance polymers, PRODEVAL specializes in treating organic waste for biomethane production, and Infologic develops ERP software for various industries.

🇫🇷 Drôme · 30 companies · Updated Nov 11, 2026

| # | Company | Industry | Headquarters | Employees | Founded |
|---|---|---|---|---|---|
| 1 | [HM.CLAUSE](https://www.tamtam.ai/c/hm-clause) (hmclause.com)<br>Creating the vegetable seeds of tomorrow, collaborating with growers and partners globally, understanding agricultural challenges through close customer proximity. | Farming | 🇫🇷 Portes-lès-Valence | 1,913 |  |
| 2 | [Crouzet](https://www.tamtam.ai/c/crouzet) (crouzet.com)<br>A manufacturer providing customized mechatronic components for aerospace, transportation, energy, and machinery industries Specializing in automation, motion, sensors, controls, and instrumentation solutions | Aviation and Aerospace Component Manufacturing | 🇫🇷 Valence | 721 | 1921 |
| 3 | [COP Chimie](https://www.tamtam.ai/c/cop-chimie) (cop-chimie.com)<br>Manufacturing and supplying innovative, high-performance polymers for external orthopedic devices, supporting craft, industry, and research worldwide with sustainable chemistry. | Chemical Manufacturing | 🇫🇷 Saint-Nazaire-en-Royans | 524 | 1987 |
| 4 | [Groupe LPG®](https://www.tamtam.ai/c/groupe-lpg) (lpg-group.com)<br>Designs and commercializes non-invasive cellular stimulation treatments for medical and aesthetic applications, serving healthcare, beauty professionals, and the public worldwide. | Wellness and Fitness Services | 🇫🇷 Valence | 484 | 1986 |
| 5 | [PRODEVAL](https://www.tamtam.ai/c/prodeval) (prodeval.com)<br>A leading company specializing in treating organic waste through anaerobic digestion, producing biomethane for city gas networks and BioCNG vehicles worldwide | Services for Renewable Energy | 🇫🇷 Châteauneuf-sur-Isère | 401 | 1990 |
| 6 | [AMPLITUDE](https://www.tamtam.ai/c/amplitude) (amplitude-ortho.com)<br>Develops and markets high-end orthopedic surgical products for hip and knee pathologies, innovating with surgeons for patient and hospital needs. | Medical Equipment Manufacturing | 🇫🇷 Valence | 373 | 1997 |
| 7 | [ITW Construction Products - Continental Europe](https://www.tamtam.ai/c/itw-construction-products-continental-europe) (careers.itw.com)<br>ITW Construction Continental Europe designs, produces, and sells premium construction products, emphasizing diversity, inclusion, and employee development while prioritizing customer needs and innovation | Construction | 🇫🇷 Bourg-lès-Valence | 330 | 1951 |
| 8 | [Infologic](https://www.tamtam.ai/c/infologic) (infologic-copilote.fr)<br>Develops and integrates ERP software solutions for agro-industry, cosmetics, plant products, and construction businesses, enhancing their operational management with comprehensive tools. | Software Development | 🇫🇷 Bourg-lès-Valence | 293 | 1982 |
| 9 | [SODIMAS](https://www.tamtam.ai/c/sodimas) (sodimas.com)<br>A French elevator equipment manufacturer with a focus on sustainability, innovation, and international presence, providing solutions for repair and modernization | Industrial Machinery Manufacturing | 🇫🇷 Pont-de-l'Isère | 276 | 1975 |
| 10 | [CAN](https://www.tamtam.ai/c/can) (can.fr)<br>Specializing in difficult access works since 1977, this company is a leader in rope access services | Civil Engineering | 🇫🇷 Mirmande | 273 | 1977 |
| 11 | [COVAL](https://www.tamtam.ai/c/coval) (coval.com)<br>Designs and manufactures advanced vacuum automation components and systems for industrial applications, enhancing productivity and safety worldwide. | Automation Machinery Manufacturing | 🇫🇷 Montélier | 200 | 1986 |
| 12 | [Groupe VINCENT](https://www.tamtam.ai/c/groupe-vincent) (groupe-vincent.fr)<br>Leading French company specializing in lifting, bodywork construction, and handling equipment distribution with a strong heritage and service focus. | Transportation Equipment Manufacturing | 🇫🇷 Étoile-sur-Rhône | 186 | 1884 |
| 13 | [SPIT PASLODE France](https://www.tamtam.ai/c/spit-paslode-france) (spitpaslode.fr)<br>Manufacture and supply of fastening systems including nails, staples, chemical and mechanical anchors, and power tools for construction. | Industrial Machinery Manufacturing | 🇫🇷 Bourg-lès-Valence | 178 | 1951 |
| 14 | [EXSTO Group](https://www.tamtam.ai/c/exsto-group) (exsto.com)<br>Specializes in plastics processing and polymer expertise to design and produce products that enhance clients' performance and competitiveness. | Plastics Manufacturing | 🇫🇷 Romans-sur-Isère | 122 | 1976 |
| 15 | [LAFUMA MOBILIER](https://www.tamtam.ai/c/lafuma-mobilier) (lafuma-mobilier.fr)<br>Designing, manufacturing durable, comfortable, sustainable furniture for indoor and outdoor spaces, including professional and individual clients, specializing in relaxation seating with a medical collaboration. | Furniture and Home Furnishings Manufacturing | 🇫🇷 Anneyron | 107 | 2014 |
| 16 | [CTH Agri](https://www.tamtam.ai/c/cth-agri) (cth.fr)<br>Manufacture and distribute hygiene and nutrition products and equipment for agriculture, with strong R&D and customer focus. | Farming | 🇫🇷 Romans-sur-Isère | 104 | 1982 |
| 17 | [METALLIANCE](https://www.tamtam.ai/c/metalliance) (metalliance-tsi.com)<br>Design and manufacture of fully electric off-road vehicles and battery systems for transport and energy infrastructure construction sectors. | Industrial Machinery Manufacturing | 🇫🇷 Saint-Vallier | 98 | 1923 |
| 18 | [Bontoux](https://www.tamtam.ai/c/bontoux) (bontoux.com)<br>Production and distillation of essential oils and natural extracts for flavors, fragrances, cosmetics, pharmaceuticals, and aromatherapy worldwide. | Chemical Manufacturing | 🇫🇷 Saint-Auban-sur-l'Ouvèze | 93 | 1898 |
| 19 | [Vanatome](https://www.tamtam.ai/c/vanatome) (vanatome.com)<br>industrial sealing systems for nuclear, defense, and low-carbon solutions, ensuring reliability, expertise, and innovation for energy needs. | Primary Metal Manufacturing | 🇫🇷 Saint-Vallier | 83 |  |
| 20 | [SAFI Valves](https://www.tamtam.ai/c/safi-valves) (safi-valves.com)<br>Design, development, and production of industrial plastic valves providing quality, safety, and tailored solutions for various industries worldwide. | Chemical Manufacturing | 🇫🇷 Taulignan | 65 | 1963 |
| 21 | [SNIG](https://www.tamtam.ai/c/snig) (tuyauterie-chaudronnerie.fr)<br>A regional nuclear company in Rhône-Alpes specializing in industrial piping, boiler making, welding, and integrated engineering for nuclear facilities | Industrial Machinery Manufacturing | 🇫🇷 Pierrelatte | 62 | 2004 |
| 22 | [Chaussy](https://www.tamtam.ai/c/chaussy) (chaussygomez.fr)<br>Specializes in mechanical, electrical, and automated design, fabrication, maintenance, revamping, quality control, and site services for industrial installations. | Industrial Machinery Manufacturing | 🇫🇷 Donzère | 61 |  |
| 23 | [Groupe COURBIS](https://www.tamtam.ai/c/groupe-courbis) (groupe-courbis.com)<br>Development of advanced polymer technologies focused on innovation, simplicity, and value addition, supported by strong company values. | Plastics Manufacturing | 🇫🇷 Romans-sur-Isère | 60 | 1964 |
| 24 | [Millet Innovation](https://www.tamtam.ai/c/millet-innovation) (access.epitact.com)<br>Specialized in developing unique production tools and methods to control product quality from start to finish, ensuring high standards. | Pharmaceutical Manufacturing | 🇫🇷 Loriol-sur-Drôme | 54 | 1998 |
| 25 | [Vignal-Artru](https://www.tamtam.ai/c/vignal-artru) (vignal-artru.com)<br>Specializing in high precision mechanics for over 50 years, the company manufactures hydraulic components, satellite parts, and complex assemblies for aeronautics, space, medical, and defense industries | Mechanical Or Industrial Engineering | 🇫🇷 Chabeuil | 53 | 1959 |
| 26 | [Dracula Technologies](https://www.tamtam.ai/c/dracula-technologies) (dracula-technologies.com)<br>Specializes in organic photovoltaic technology, creating printed power-generating solutions from ambient light for battery-free IoT devices, meeting corporate green solution demands. | Renewable Energy Semiconductor Manufacturing | 🇫🇷 Valence | 52 | 2012 |
| 27 | [IPM France](https://www.tamtam.ai/c/ipm-france) (ipmfrance.fr)<br>Design manufacture deploy maintain interactive kiosks with middleware applications for mobility healthcare telecoms local authorities leisure sectors | IT Services and IT Consulting | 🇫🇷 Romans-sur-Isère | 51 | 2001 |
| 28 | [Markem-Imaje France](https://www.tamtam.ai/c/markem-imaje-france) (markem-imaje.com)<br>Provides marking, coding, and traceability solutions with software and services to ensure product authenticity, safety, and supply chain efficiency. | Automation Machinery Manufacturing | 🇫🇷 Châteauneuf-sur-Isère | 50 |  |
| 29 | [Phytéo Laboratoire](https://www.tamtam.ai/c/phyteo-laboratoire-aouste-sur-sye) (phyteo-laboratoire.com)<br>Phytéo Laboratoire specializes in developing and producing Made in France food supplements, offering tailored support and solutions based on plant extraction expertise | Wellness and Fitness Services | 🇫🇷 Aouste-sur-Sye | 48 | 2013 |
| 30 | [Nature Cos Officiel](https://www.tamtam.ai/c/nature-cos-officiel) (naturecos.org)<br>Manufacturer specializing in organic and natural cosmetics, producing skincare and beauty products with environmentally friendly ingredients and sustainable practices. | Personal Care Product Manufacturing | 🇫🇷 Bourg-de-Péage | 46 | 2002 |

## How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 11, 2026.

## More company lists in the Drôme department

- [The largest companies in the Drôme department](https://www.tamtam.ai/l/largest-companies-drome) (501)
- [Manufacturers in the Drôme department](https://www.tamtam.ai/l/manufacturers-drome) (76)
- [Multinational companies in the Drôme department](https://www.tamtam.ai/l/multinational-companies-drome) (55)
- [Retail chains in the Drôme department](https://www.tamtam.ai/l/retail-chains-drome) (53)
- [Family-owned companies in the Drôme department](https://www.tamtam.ai/l/family-owned-companies-drome) (41)
- [Hardware manufacturers in the Drôme department](https://www.tamtam.ai/l/hardware-companies-drome) (37)
- [Distributors and wholesalers in the Drôme department](https://www.tamtam.ai/l/distributors-and-wholesalers-drome) (28)
- [Contract manufacturers in the Drôme department](https://www.tamtam.ai/l/contract-manufacturers-drome) (25)

## The same list elsewhere in France

- [Companies with in-house R&D in France](https://www.tamtam.ai/l/r-and-d-companies-france) (8,750)
- [Companies with in-house R&D in Île-de-France](https://www.tamtam.ai/l/r-and-d-companies-ile-de-france) (2,695)
- [Companies with in-house R&D in Auvergne-Rhône-Alpes](https://www.tamtam.ai/l/r-and-d-companies-auvergne-rhone-alpes) (1,460)
- [Companies with in-house R&D in Occitanie](https://www.tamtam.ai/l/r-and-d-companies-occitanie) (680)
- [Companies with in-house R&D in Grand Est](https://www.tamtam.ai/l/r-and-d-companies-grand-est) (640)
- [Companies with in-house R&D in Provence-Alpes-Côte d'Azur](https://www.tamtam.ai/l/r-and-d-companies-provence-alpes-cote-dazur) (613)
- [Companies with in-house R&D in Nouvelle-Aquitaine](https://www.tamtam.ai/l/r-and-d-companies-nouvelle-aquitaine) (566)
- [Companies with in-house R&D in the Hauts-de-Seine department](https://www.tamtam.ai/l/r-and-d-companies-hauts-de-seine) (510)
- [Companies with in-house R&D in the Rhône department](https://www.tamtam.ai/l/r-and-d-companies-rhone) (509)
- [Companies with in-house R&D in Pays de la Loire](https://www.tamtam.ai/l/r-and-d-companies-pays-de-la-loire) (480)
- [Companies with in-house R&D in Hauts-de-France](https://www.tamtam.ai/l/r-and-d-companies-hauts-de-france) (410)
- [Companies with in-house R&D in Brittany](https://www.tamtam.ai/l/r-and-d-companies-brittany) (366)
- [Companies with in-house R&D in the Haute-Garonne department](https://www.tamtam.ai/l/r-and-d-companies-haute-garonne) (323)
- [Companies with in-house R&D in the Bouches-du-Rhône department](https://www.tamtam.ai/l/r-and-d-companies-bouches-du-rhone) (321)
- [Companies with in-house R&D in the Isère department](https://www.tamtam.ai/l/r-and-d-companies-isere) (304)
- [Companies with in-house R&D in Bourgogne-Franche-Comté](https://www.tamtam.ai/l/r-and-d-companies-bourgogne-franche-comte) (261)
- [Companies with in-house R&D in the Nord department](https://www.tamtam.ai/l/r-and-d-companies-nord) (237)
- [Companies with in-house R&D in Normandy](https://www.tamtam.ai/l/r-and-d-companies-normandy) (227)
- [Companies with in-house R&D in the Gironde department](https://www.tamtam.ai/l/r-and-d-companies-gironde) (225)
- [Companies with in-house R&D in the Loire-Atlantique department](https://www.tamtam.ai/l/r-and-d-companies-loire-atlantique) (207)
- [Companies with in-house R&D in the Essonne department](https://www.tamtam.ai/l/r-and-d-companies-essonne) (198)
- [Companies with in-house R&D in Centre-Val de Loire](https://www.tamtam.ai/l/r-and-d-companies-centre-val-de-loire) (195)
- [Companies with in-house R&D in Paris](https://www.tamtam.ai/l/r-and-d-companies-paris) (1,249)
- [Companies with in-house R&D in Lyon](https://www.tamtam.ai/l/r-and-d-companies-lyon) (192)

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Source: https://www.tamtam.ai/l/r-and-d-companies-drome