# 100 leading companies with in-house R&D in Grand Est

Tamtam tracks 640 companies with in-house R&D headquartered in Grand Est. This list ranks the 100 largest by number of employees on LinkedIn, led by Decathlon, Dassault Systèmes and Hermès. Their median headcount is 549. Half of them were founded in 1970 or later. The most common headquarters are Strasbourg (8), Nancy (4) and Reims (4).

The companies listed here are primarily large firms, many with an international presence, engaged in a variety of sectors including retail, technology, and manufacturing. Notable examples include Decathlon, a global sports retailer, and Dassault Systèmes, which develops virtual world platforms. Hermès, a family-owned French house, creates high-quality objects, while KIABI is a French ready-to-wear retailer.

Several companies are headquartered outside the Grand Est region, such as Decathlon in Villeneuve-d'Ascq and Dassault Systèmes in Velizy-Villacoublay. However, there is a notable presence of higher education institutions within the Grand Est, with Universite de Lorraine in Nancy and University of Strasbourg in Strasbourg, indicating a focus on research and development within the region.

🇫🇷 Grand Est · 100 companies · Updated Nov 12, 2026

| # | Company | Industry | Headquarters | Employees | Founded |
|---|---|---|---|---|---|
| 1 | [Decathlon](https://www.tamtam.ai/c/decathlon-ay-champagne) (decathlon-united.media)<br>A global sports retailer offering affordable world-class products for beginners to professionals, making sports accessible worldwide | Wholesale | 🇫🇷 Villeneuve-d'Ascq | 103,020 | 1976 |
| 2 | [Dassault Systèmes](https://www.tamtam.ai/c/dassault-systemes) (3ds.com)<br>Pioneering virtual worlds since 1981, this company offers a platform enabling customers across industries to collaborate, imagine, and create sustainable innovations for real-life impact. | Software Development | 🇫🇷 Velizy-Villacoublay | 27,414 |  |
| 3 | [Hermès](https://www.tamtam.ai/c/hermes-ay-champagne) (hermes.com)<br>Family-owned French house, creates and sells high-quality objects since 1837, cultivating freedom, transmitting exceptional know-how through 16 artisanal métiers. | Retail Apparel and Fashion | 🇫🇷 Paris | 26,494 | 1837 |
| 4 | [KIABI](https://www.tamtam.ai/c/kiabi) (kiabi.com)<br>French ready-to-wear retailer revolutionizing fashion with low-cost clothing for the whole family, designed by in-house fashion designers. | Retail | 🇫🇷 Hem | 11,444 | 1978 |
| 5 | [Disneyland Paris](https://www.tamtam.ai/c/disneyland-paris) (disneycareers.com)<br>Creates magical experiences for guests through a diverse team. Offers numerous career paths across various departments, from park operations to corporate functions. | Entertainment Providers | 🇫🇷 Chessy | 10,460 | 1992 |
| 6 | [Thales Alenia Space](https://www.tamtam.ai/c/thales-alenia-space) (thalesaleniaspace.com)<br>Designing satellite-based systems for telecommunications, navigation, Earth observation, defense, and space exploration, ensuring connections, monitoring our planet, and discovering the Universe. | Aviation and Aerospace Component Manufacturing | 🇫🇷 | 8,168 |  |
| 7 | [Groupe VIVESCIA](https://www.tamtam.ai/c/groupe-vivescia) (vivescia.com)<br>International cooperative agricultural and food processing group specializing in grain cultivation and value addition, serving farmers and consumers worldwide | Food and Beverage Manufacturing | 🇫🇷 Reims | 7,100 |  |
| 8 | [European Space Agency - ESA](https://www.tamtam.ai/c/european-space-agency-esa) (esa.int)<br>Coordinates member resources for space capability development, ensuring benefits for European and global citizens through ambitious space programs. | Space Research and Technology | 🇫🇷 Paris | 7,016 | 1975 |
| 9 | [Universite de Lorraine](https://www.tamtam.ai/c/universite-de-lorraine) (univ-lorraine.fr)<br>Leading campus in France, promoting knowledge sharing from basic to humanities, creating interdisciplinary ecosystems to drive innovation, economic and social development Offering diverse academic fields | Higher Education | 🇫🇷 Nancy | 6,783 | 2012 |
| 10 | [Air Liquide Healthcare](https://www.tamtam.ai/c/air-liquide-healthcare) (airliquide.com)<br>Provides home healthcare services, medical gases, and specialty ingredients. Supports chronic patients and supplies medical products to hospitals and healthcare professionals. | Health and Human Services | 🇫🇷 Bagneux | 6,583 |  |
| 11 | [University of Strasbourg](https://www.tamtam.ai/c/university-of-strasbourg) (unistra.fr)<br>Research and education in life sciences, health, chemistry, physics, humanities, fostering innovation and partnerships with socio-economic sectors. | Higher Education | 🇫🇷 Strasbourg | 5,938 |  |
| 12 | [Lesaffre](https://www.tamtam.ai/c/lesaffre) (lesaffre.com)<br>A global leader in fermentation with a focus on food, health, naturalness, and sustainability, harnessing microorganisms to address the challenge of feeding the growing population | Food and Beverage Manufacturing | 🇫🇷 | 5,337 | 1853 |
| 13 | [CHRU de Strasbourg - Hôpitaux Universitaires de Strasbourg](https://www.tamtam.ai/c/chru-de-strasbourg-hopitaux-universitaires-de-strasbourg) (chru-strasbourg.fr)<br>Provides comprehensive medical services across six specialized hospitals and three logistics sites focusing on surgery, obstetrics, orthopedics, and diverse clinical treatments. | Hospitals and Health Care | 🇫🇷 Strasbourg | 3,268 |  |
| 14 | [OVHcloud](https://www.tamtam.ai/c/ovhcloud) (ovhcloud.com)<br>Global player and leading European cloud provider operating 450,000 servers within 43 data centers across 4 continents, reaching 1.6 million customers. | Software Development | 🇫🇷 Roubaix | 3,251 | 1999 |
| 15 | [Socomec Group](https://www.tamtam.ai/c/socomec-group) (socomec.com)<br>Established in 1922, this independent industrial group specializes in ensuring the availability, control, and safety of low voltage electrical networks worldwide, generating a turnover of 725 M€ in 2022 | Appliances, Electrical, and Electronics Manufacturing | 🇫🇷 Benfeld | 3,166 | 1922 |
| 16 | [Salomon](https://www.tamtam.ai/c/salomon) (salomon.com)<br>Designing, manufacturing, and distributing innovative sporting goods since 1947, shaping the future of sport with gear for various outdoor activities. | Sporting Goods Manufacturing | 🇫🇷 Annecy | 2,848 | 1947 |
| 17 | [CHRU de Nancy](https://www.tamtam.ai/c/chru-de-nancy) (chru-nancy.fr)<br>Provides comprehensive medical-surgical care for all ages, conducts biomedical research, trains health professionals, and significantly contributes to the regional economy and employment. | Hospitals and Health Care | 🇫🇷 Nancy | 2,571 | 1883 |
| 18 | [KUHN Group](https://www.tamtam.ai/c/kuhn-group) (kuhn.com)<br>Provides top-quality, innovative agricultural equipment solutions. Focuses on improving farmers' efficiency and contributing to sustainable food production globally. | Machinery Manufacturing | 🇫🇷 Saverne | 2,464 | 1828 |
| 19 | [Technology & Strategy](https://www.tamtam.ai/c/technology-and-strategy) (tands.com)<br>Provides engineering, digital, and consulting services, developing innovative projects for industrial, automotive, and financial sectors with a focus on human values and global presence. | IT Services and IT Consulting | 🇫🇷 Schiltigheim | 2,370 | 2008 |
| 20 | [Ginger](https://www.tamtam.ai/c/ginger-ay-champagne) (groupeginger.com)<br>Leader in independent engineering, specializing in soil, water, material, and environmental engineering, securing projects, optimizing durability, and integrating them environmentally. | Business Consulting and Services | 🇫🇷 Élancourt | 1,777 | 1933 |
| 21 | [Liebherr Mining](https://www.tamtam.ai/c/liebherr-mining) (liebherr.com)<br>A global technology company providing innovative mining solutions, equipment, and support services to help customers thrive in challenging conditions | Mining | 🇫🇷 Colmar | 1,766 | 1949 |
| 22 | [Ifremer](https://www.tamtam.ai/c/ifremer) (ifremer.fr)<br>An organization conducting research on oceans, marine environment, and sustainable maritime activities, providing knowledge, innovation, and expertise for public policy and socio-economic activities | Research Services | 🇫🇷 | 1,703 | 1984 |
| 23 | [Axima Réfrigération France](https://www.tamtam.ai/c/axima-refrigeration-france) (equans.fr)<br>Industrial refrigeration specialist providing installation and maintenance services for food industries, retail, logistics, and chemistry through a network of eighty French regional agencies. | HVAC and Refrigeration Equipment Manufacturing | 🇫🇷 Bischheim | 1,690 | 1876 |
| 24 | [Petit Bateau](https://www.tamtam.ai/c/petit-bateau) (petit-bateau.com)<br>Creating durable clothing for over 125 years, focusing on freedom, quality, and sustainability | Textile Manufacturing | 🇫🇷 Troyes | 1,561 | 1893 |
| 25 | [GRTgaz](https://www.tamtam.ai/c/grtgaz) (natrangroupe.com)<br>Builds, maintains, and develops 85% of France's high-pressure natural gas transmission network, ensuring safe, reliable, and cost-effective gas delivery to industrial sites and public distribution. | Oil and Gas | 🇫🇷 Bois-Colombes | 1,512 | 2005 |
| 26 | [Exide Group](https://www.tamtam.ai/c/exide-group) (exidegroup.com)<br>Designs, manufactures, and markets advanced battery technologies for automotive, industrial, and specialized applications, focusing on efficient energy solutions and customer productivity. | Appliances, Electrical, and Electronics Manufacturing | 🇫🇷 Gennevilliers | 1,440 |  |
| 27 | [CHU de Reims](https://www.tamtam.ai/c/chu-de-reims) (chu-reims.fr)<br>A leading hospital center in Reims offering high-quality healthcare, education, and research services in various medical specialties, with a focus on collaboration and innovation | Hospitals and Health Care | 🇫🇷 Reims | 1,412 |  |
| 28 | [Vantiva](https://www.tamtam.ai/c/vantiva) (vantiva.com)<br>Global technology leader providing broadband, video, and IoT smart systems, connecting people worldwide. Specializes in hardware design and supply chain expertise. | Telecommunications | 🇫🇷 Paris | 1,380 |  |
| 29 | [Saint-Gobain PAM Canalisation](https://www.tamtam.ai/c/saint-gobain-pam-canalisation) (pamline.com)<br>Global manufacturer and supplier of ductile iron pipe solutions for water transport, sewerage, industrial applications, and drainage systems across diverse international markets. | Utilities | 🇫🇷 Pont-à-Mousson | 1,190 |  |
| 30 | [ERT Technologies SAS](https://www.tamtam.ai/c/ert-technologies-sas) (ert-technologies.fr)<br>Designs, builds, operates, and maintains multi-technical telecommunications infrastructure and network architectures across France for operators, local authorities, and major accounts. | Telecommunications | 🇫🇷 Thaon-les-Vosges | 1,186 | 2000 |
| 31 | [BUGATTI](https://www.tamtam.ai/c/bugatti) (bugatti.com)<br>Designing, developing, and manufacturing high-performance, luxurious hyper sports cars, while also expanding into luxury lifestyle products and collaborations. | Motor Vehicle Manufacturing | 🇫🇷 Molsheim | 1,175 |  |
| 32 | [ISAE-SUPAERO](https://www.tamtam.ai/c/isae-supaero) (isae-supaero.fr)<br>Educates in aerospace engineering, providing a wide range of science and engineering degrees, including master's, advanced masters, doctoral, and executive programs. | Education | 🇫🇷 Toulouse | 1,113 | 2007 |
| 33 | [SIAAP](https://www.tamtam.ai/c/siaap) (siaap.fr)<br>A unique public company in Europe, providing interdepartmental wastewater treatment services for 9 million residents in the Paris metropolitan area | Government Administration | 🇫🇷 | 1,071 | 1970 |
| 34 | [Clayens NP](https://www.tamtam.ai/c/clayens-np) (clayens.com)<br>Transforms high-performance polymers, composites, and precision metal parts, offering tailored solutions from project to production across diverse industrial sectors. | Manufacturing | 🇫🇷 Genas | 978 | 1931 |
| 35 | [Haulotte](https://www.tamtam.ai/c/haulotte) (haulotte.com)<br>Design, manufacture, and sale of aerial work platforms through global factories and subsidiaries, providing safe, innovative solutions for construction and industrial sectors. | Construction | 🇫🇷 Lorette | 975 | 1985 |
| 36 | [CORDON GROUP](https://www.tamtam.ai/c/cordon-group) (cordongroup.com)<br>Provides electronic product maintenance, repair, logistics, manufacturing, and engineering across 40 sites in 12 countries for various partners. | Telecommunications | 🇫🇷 Dinan | 907 | 1989 |
| 37 | [Institut Montsouris](https://www.tamtam.ai/c/institut-montsouris) (imm.fr)<br>Private healthcare institution in Paris providing high-quality, comprehensive patient care with recognized medical expertise and top national and international rankings. | Hospitals and Health Care | 🇫🇷 | 893 | 1999 |
| 38 | [Groupe LSDH](https://www.tamtam.ai/c/groupe-lsdh) (lsdh.fr)<br>Processes and packages various liquid foods in cartons or bottles, and fresh salads, managing the entire supply chain from sourcing to delivery. | Food and Beverage Manufacturing | 🇫🇷 Saint-Denis-de-l'Hôtel | 864 |  |
| 39 | [Université de Haute-Alsace - UHA](https://www.tamtam.ai/c/universite-de-haute-alsace-uha) (uha.fr)<br>Multidisciplinary university offering diverse degree programs, strong research teams, professional training, and close socio-economic partnerships in Alsace region. | Higher Education | 🇫🇷 Mulhouse | 850 | 1975 |
| 40 | [Groupe Lea Nature](https://www.tamtam.ai/c/groupe-lea-nature) (recrutement-leanature.com)<br>Develops and manufactures natural organic food, health, beauty, and home products across twenty-one French production sites for diverse distribution networks and sustainability. | Personal Care Product Manufacturing | 🇫🇷 Périgny | 814 | 1993 |
| 41 | [KP1](https://www.tamtam.ai/c/kp1) (kp1.fr)<br>Specialist in prefabricated building components including beams, slabs, and thermal bridge breakers, with extensive manufacturing across France. | Wholesale Building Materials | 🇫🇷 Avignon | 793 | 1959 |
| 42 | [Fives Nordon](https://www.tamtam.ai/c/fives-nordon) (fivesgroup.com)<br>Designs, manufactures, installs, and maintains high-tech industrial piping networks and equipment for clients in diverse demanding sectors, from engineering to on-site assembly. | Mechanical Or Industrial Engineering | 🇫🇷 Nancy | 661 | 1904 |
| 43 | [ICN Business School](https://www.tamtam.ai/c/icn-business-school) (icn-artem.com)<br>ICN Business School provides innovative and transdisciplinary education to develop responsible professionals capable of acting in a globalized economic environment | Higher Education | 🇫🇷 Nancy | 651 | 1905 |
| 44 | [Université de Haute-Alsace Mulhouse-Colmar](https://www.tamtam.ai/c/universite-de-haute-alsace-mulhouse-colmar) (uha.fr)<br>It offers multidisciplinary higher education programs from undergraduate to doctorate, conducts fundamental and applied research, and fosters innovation in various scientific and humanities fields. | Higher Education | 🇫🇷 Mulhouse | 649 | 1975 |
| 45 | [Rector Lesage](https://www.tamtam.ai/c/rector-lesage) (rector.fr)<br>Specializes in precast and prestressed concrete floor systems, offering durable, innovative, and environmentally conscious construction solutions since 1953. | Construction | 🇫🇷 Mulhouse | 628 | 1953 |
| 46 | [MAGNUM](https://www.tamtam.ai/c/magnum) (magnum.fr)<br>A specialist in audiovisual technical solutions for events, providing services, equipment rental, and sale of used equipment for over 30 years | Events Services | 🇫🇷 Gonesse | 608 | 1980 |
| 47 | [Centre François Baclesse](https://www.tamtam.ai/c/centre-francois-baclesse) (baclesse.fr)<br>A leading cancer center in Caen, France, offering top-notch care, education, and research in oncology Specializing in proton therapy for improved cancer treatment | Hospitals and Health Care | 🇫🇷 Caen | 600 | 1925 |
| 48 | [Bertin Technologies](https://www.tamtam.ai/c/bertin-technologies) (bertin-technologies.com)<br>Supplies high-end instrumentation, components, equipment, and systems for critical applications such as defense, nuclear, environment, and scientific knowledge improvement. | Measuring and Control Instrument Manufacturing | 🇫🇷 Montigny-Le-Bretonneux | 566 | 1956 |
| 49 | [EM Strasbourg Business School](https://www.tamtam.ai/c/em-strasbourg-business-school) (em-strasbourg.com)<br>Business school offering international programs, triple accredited and integrated into a university, supported by corporate partners and a strong alumni network. | Higher Education | 🇫🇷 Strasbourg | 555 | 1919 |
| 50 | [Eurofins Environment Testing France](https://www.tamtam.ai/c/eurofins-environment-testing-france) (eurofins.fr)<br>Provides extensive analytical testing services across food, environment, pharmaceuticals, agroscience, genomics, pharmacology, and clinical diagnostics worldwide. | Biotechnology Research | 🇫🇷 Saverne | 549 | 1987 |
| 51 | [SOPREMA France](https://www.tamtam.ai/c/soprema-france) (soprema.fr)<br>A leading independent family-owned group specializing in innovative, energy-efficient building products worldwide, with a focus on waterproofing, insulation, and roofing solutions | Wholesale Building Materials | 🇫🇷 Strasbourg | 548 | 1908 |
| 52 | [De Dietrich](https://www.tamtam.ai/c/de-dietrich) (dedietrich.com)<br>Global leader in design, supply of systems, process equipment, solutions for pharma, food, green chemistry, and chemical industries. | Industrial Machinery Manufacturing | 🇫🇷 Niederbronn les Bains | 533 | 1684 |
| 53 | [LACROIX](https://www.tamtam.ai/c/lacroix-ay-champagne) (lacroix-group.com)<br>Develops and manufactures electronic equipment and connected IoT solutions to create sustainable, safer environments, addressing challenges in various sectors including automotive, industrial, and smart infrastructure. | Appliances, Electrical, and Electronics Manufacturing | 🇫🇷 Saint-Herblain | 531 | 1936 |
| 54 | [EURO PROTECTION SURVEILLANCE](https://www.tamtam.ai/c/euro-protection-surveillance) (eps.fr)<br>French market leader providing twenty-four-seven remote alarm monitoring services for residential and professional properties with nearly forty years of specialized industry expertise. | Consumer Services | 🇫🇷 Strasbourg | 524 | 1986 |
| 55 | [Ekinops](https://www.tamtam.ai/c/ekinops) (ekinops.com)<br>Provides open, trusted, and innovative network connectivity solutions. Delivers high value-added software-driven solutions for optical transport and virtualized managed enterprise services. | Telecommunications | 🇫🇷 Lannion | 509 | 2003 |
| 56 | [IOC](https://www.tamtam.ai/c/ioc) (ioc.eu.com)<br>Provides personalized oenological advice, wine analysis, innovative products, and support throughout winemaking from harvest to bottling worldwide. | Wine & Spirits | 🇫🇷 Mardeuil | 481 | 1890 |
| 57 | [CEE R. SCHISLER](https://www.tamtam.ai/c/cee-r-schisler) (ceeschisler.fr)<br>Manufacturing diverse paper packaging products including bags, cups, wraps, and specialized items for shopping and fast food industries. | Packaging and Containers Manufacturing | 🇫🇷 Thouars cedex | 458 | 1950 |
| 58 | [COMEPA](https://www.tamtam.ai/c/comepa) (comepa.com)<br>Manufacture and supply of single-use medical devices designed specifically for surgical procedures and related medical applications. | Medical Equipment Manufacturing | 🇫🇷 | 440 |  |
| 59 | [Axon' Cable Group](https://www.tamtam.ai/c/axon-cable-group) (axon-cable.com)<br>Design and manufacture custom electrical connections, cables, and connectors for harsh environments across automotive, aerospace, defense, medical, and industrial sectors. | Appliances, Electrical, and Electronics Manufacturing | 🇫🇷 Montmirail | 438 | 1965 |
| 60 | [Institut de Cancérologie de Lorraine - ICL](https://www.tamtam.ai/c/institut-de-cancerologie-de-lorraine-icl) (icl-lorraine.fr)<br>A cancer center in Lorraine providing specialized care for various types of cancer, conducting research projects, receiving donations for research and patient support, and offering cancer education | Hospitals and Health Care | 🇫🇷 Vandœuvre-lès-Nancy | 427 |  |
| 61 | [BDR THERMEA FRANCE](https://www.tamtam.ai/c/bdr-thermea-france)<br>Provides innovative heating, air-conditioning, and domestic hot water solutions through well-known French brands focused on sustainable thermal comfort. | Industrial Machinery Manufacturing | 🇫🇷 Mertzwiller | 417 | 2018 |
| 62 | [Pharmagest Interactive](https://www.tamtam.ai/c/pharmagest-interactive) (pharmagest.com)<br>The company develops innovative technological solutions to enhance patient comfort and health, support pharmacists in coordinating healthcare, and improve patient monitoring and home care | Software Development | 🇫🇷 Villers-lès-Nancy | 414 | 1984 |
| 63 | [ASCOMETAL](https://www.tamtam.ai/c/ascometal) (ascometal.com)<br>Specializing in long engineering steel products for Automotive, Bearings, Oil & Gas, and Mechanical Engineering industries, designing, manufacturing, and delivering worldwide | Mining | 🇫🇷 Hagondange | 411 | 2018 |
| 64 | [Poulaillon](https://www.tamtam.ai/c/poulaillon) (poulaillon.fr)<br>A bakery, pastry, and catering company based in Alsace and the Grand-Est region since 1973, offering traditional French products 🥖🇫🇷 | Food and Beverage Manufacturing | 🇫🇷 Wittelsheim | 397 | 1973 |
| 65 | [ACD](https://www.tamtam.ai/c/acd) (acd-groupe.fr)<br>Provides modular software suites for accounting professionals, supporting digitalization with comprehensive production and management tools, specialized modules, and third-party integrations. | Software Development | 🇫🇷 Tours | 377 | 2010 |
| 66 | [MECATHERM](https://www.tamtam.ai/c/mecatherm) (mecatherm.fr)<br>A global leader in industrial bakery equipment, specializing in designing and manufacturing ovens, machinery, and automatic production lines for the bakery industry worldwide | Machinery Manufacturing | 🇫🇷 Schirmeck | 373 | 1964 |
| 67 | [Piveteaubois](https://www.tamtam.ai/c/piveteaubois) (piveteaubois.com)<br>French manufacturer wood solutions construction, outdoor landscaping, wood energy. Family business, wood industry development, multiple expertise for professionals, 5 exclusive technologies. | Paper and Forest Product Manufacturing | 🇫🇷 Sainte Florence | 373 | 1948 |
| 68 | [Lohr Group](https://www.tamtam.ai/c/lohr-group) (lohr.fr)<br>Design manufacture market transport systems for goods people including car carriers piggyback rail urban mobility solutions worldwide. | Truck Transportation | 🇫🇷 Hangenbieten | 365 | 1963 |
| 69 | [Forterro FR](https://www.tamtam.ai/c/forterro-fr) (forterro.com)<br>Deploys 6 ERP solutions and 1 planning solution, covering business processes for startups, SMEs, and multi-site industrial groups to structure activity, optimize management, and foster growth. | Software Development | 🇫🇷 Caen | 364 | 2021 |
| 70 | [Fibre Excellence](https://www.tamtam.ai/c/fibre-excellence) (fibre-excellence.com)<br>Production of pulp, biomass energy, and timber harvesting using locally sourced, PEFC certified wood supporting local French communities. | Paper and Forest Product Manufacturing | 🇫🇷 | 362 |  |
| 71 | [Centre Eugène Marquis](https://www.tamtam.ai/c/centre-eugene-marquis) (centre-eugene-marquis.fr)<br>Leading cancer center in Brittany, France. Provides medical oncology, radiotherapy, medical imaging, and nuclear medicine. Focuses on care, education, research. | Hospitals and Health Care | 🇫🇷 Rennes | 344 | 1923 |
| 72 | [Knauf France](https://www.tamtam.ai/c/knauf-france) (knauf.com)<br>Family-owned since 1932, specializing in interior solutions, sound and thermal insulation for professionals Leading global producer of construction materials | Wholesale Building Materials | 🇫🇷 Wolfgantzen | 339 | 1932 |
| 73 | [SEDIS](https://www.tamtam.ai/c/sedis) (sedis.com)<br>Leading French chain manufacturer specializing in high-performance transmission, agriculture, leaf, adapted, and conveying chains, wheels, and sprockets, with innovative chromizing process for extended life. | Industrial Machinery Manufacturing | 🇫🇷 Troyes | 338 | 1946 |
| 74 | [IMT Mines Albi](https://www.tamtam.ai/c/imt-mines-albi) (imt-mines-albi.fr)<br>French engineering school training engineers and doctors. Focus on high-level research and economic development through incubators, technopoles, and competitiveness clusters. | Higher Education | 🇫🇷 Albi | 337 | 1992 |
| 75 | [Hager France](https://www.tamtam.ai/c/hager-france) (hager.com)<br>Specializing in energy distribution and electric vehicle infrastructure management, providing tailored advice and services to meet clients' needs and requirements | Appliances, Electrical, and Electronics Manufacturing | 🇫🇷 Obernai | 337 | 1955 |
| 76 | [Malteurop](https://www.tamtam.ai/c/malteurop) (malteurop.com)<br>A global producer of malt for brewers, distillers, and food companies, with 23 industrial sites in 14 countries. | Food and Beverage Manufacturing | 🇫🇷 Reims | 337 | 1961 |
| 77 | [SYNERLAB GROUP](https://www.tamtam.ai/c/synerlab-group) (synerlab.com)<br>Pharmaceutical services company focused on innovation, enhanced capabilities, and strategic growth through mergers and acquisitions in the pharma sector. | Pharmaceutical Manufacturing | 🇫🇷 Entzheim | 337 | 2001 |
| 78 | [Groupe JVS](https://www.tamtam.ai/c/groupe-jvs) (groupe-jvs.fr)<br>The JVS Group consists of 5 specialized software and IT solution companies, focused on sectors like local government, healthcare, and water management, fostering innovation and collaboration | Software Development | 🇫🇷 Saint-Martin-sur-le-Pré | 335 | 1983 |
| 79 | [Withings](https://www.tamtam.ai/c/withings) (withings.com)<br>Develops clinically validated connected health devices, including smart scales and blood pressure monitors, enabling medical-grade measurements and long-term health insights at home. | Wellness and Fitness Services | 🇫🇷 Issy-les-Moulineaux | 333 | 2008 |
| 80 | [Novalix](https://www.tamtam.ai/c/novalix) (novalix.com)<br>Fully integrated drug discovery CRO offering support from target identification to preclinical candidates, specializing in medicinal chemistry, pharmacology, and biophysical techniques | Biotechnology Research | 🇫🇷 Strasbourg | 331 | 2002 |
| 81 | [ALSYMEX](https://www.tamtam.ai/c/alsymex) (alsymex-alcen.com)<br>Designing, manufacturing, and installing complex mechanical systems and equipment for diverse sectors including nuclear, aerospace, defense, and medical industries. | Industrial Machinery Manufacturing | 🇫🇷 Mérignac | 329 |  |
| 82 | [CLEEVEN](https://www.tamtam.ai/c/cleeven) (cleeven.com)<br>Offers engineering consulting services, focusing on delivering exceptional technical skills and human qualities to support clients in achieving their project goals. | Research Services | 🇫🇷 Lyon | 328 | 2015 |
| 83 | [Playmobil France](https://www.tamtam.ai/c/playmobil-france) (playmobil.fr)<br>Design, manufacture, and distribute iconic 7.5 cm figurines across various themes, supporting marketing, logistics, and customer services in France. | Manufacturing | 🇫🇷 | 324 | 1981 |
| 84 | [Institut supérieur d'électronique et du numérique](https://www.tamtam.ai/c/institut-superieur-d-electronique-et-du-numerique) (isen.fr)<br>Provides generalist engineering and high technology education across four French campuses as a founding member of the private Yncréa association group. | Higher Education | 🇫🇷 | 322 | 1956 |
| 85 | [Institut Godinot](https://www.tamtam.ai/c/institut-godinot) (institutgodinot.fr)<br>Comprehensive cancer care center providing treatment, research, education, and prevention services to patients in Reims and surrounding regions. | Hospitals and Health Care | 🇫🇷 Reims | 311 | 1924 |
| 86 | [ACIEO](https://www.tamtam.ai/c/acieo) (acieo.fr)<br>Specialized subsidiaries providing expert services in roofing, carpentry, and waterproofing across Western France, focusing on durable, quality construction solutions. | Construction | 🇫🇷 Aze | 292 | 2006 |
| 87 | [OREST GROUP](https://www.tamtam.ai/c/orest-group) (orestgroup.fr)<br>Specializes in jewelry manufacturing, combining industrial and artisanal skills, supporting luxury brands with precision engineering and craftsmanship. | Wholesale Luxury Goods and Jewelry | 🇫🇷 Strasbourg | 292 |  |
| 88 | [MDY](https://www.tamtam.ai/c/mdy) (mdy-france.com)<br>Company based in France, specializing in glass, ceramics, and concrete materials. | Wholesale Building Materials | 🇫🇷 Versailles | 286 | 1968 |
| 89 | [SEMIN](https://www.tamtam.ai/c/semin) (semin.com)<br>Manufacturing and supplying high-quality construction materials for building and interior renovation with focus on innovation, customer service, and environmental responsibility. | Wholesale Building Materials | 🇫🇷 Kédange-sur-Canner | 284 | 1838 |
| 90 | [HGH Infrared Systems](https://www.tamtam.ai/c/hgh-infrared-systems) (hgh-infrared.com)<br>Designs, develops, assembles, and sells optronic systems for industrial, civil, defense, and security applications, specializing in innovative infrared technology and advanced sensors. | Defense and Space Manufacturing | 🇫🇷 Igny | 283 | 1982 |
| 91 | [Lebronze alloys](https://www.tamtam.ai/c/lebronze-alloys) (lebronze-alloys.com)<br>Development and production of high-performance copper and nickel alloys with advanced metal processing technologies for various major industries. | Fabricated Metal Products | 🇫🇷 Suippes | 279 | 1934 |
| 92 | [Corplex](https://www.tamtam.ai/c/corplex) (corplex.com)<br>The company offers sustainable products designed to serve a purpose, with resilient properties to be reused instead of ending up in landfills | Packaging and Containers Manufacturing | 🇫🇷 Colmar | 276 |  |
| 93 | [Buffet Crampon](https://www.tamtam.ai/c/buffet-crampon) (buffetcrampon.com)<br>Manufactures woodwind instruments, collaborating with artisans, technicians, and musicians globally to ensure high-quality production and meet diverse musical needs across various brands. | Musicians | 🇫🇷 Mantes-la-Ville | 269 | 1825 |
| 94 | [INSA Hauts-de-France](https://www.tamtam.ai/c/insa-hauts-de-france) (insa-hautsdefrance.fr)<br>National Applied Science Institute, part of a polytechnic university, offering engineering degrees, and conducting research with high-level technological platforms and strong industry ties. | Education Administration Programs | 🇫🇷 Aulnoy-lez-Valenciennes | 265 | 2020 |
| 95 | [Divalto](https://www.tamtam.ai/c/divalto) (divalto.com)<br>It provides cloud-based management solutions, including CRM and ERP, tailored for various industries, enhancing collaboration and user experience. | Software Development | 🇫🇷 Entzheim | 265 | 1982 |
| 96 | [SOPROFEN](https://www.tamtam.ai/c/soprofen) (soprofen.fr)<br>French designer, extruder, and manufacturer of closures, consistently bringing new ideas and technical solutions to installers and users for 40 years. | Wholesale | 🇫🇷 Mertzwiller | 264 | 1984 |
| 97 | [Groupe Airwell](https://www.tamtam.ai/c/groupe-airwell) (airwell.com)<br>French brand specializing in air conditioning and heating solutions, present in over 80 countries since 1947, a reference in the industry. | Renewable Energy Equipment Manufacturing | 🇫🇷 Montigny-le-Bretonneux | 263 | 1947 |
| 98 | [IRH INGENIEUR CONSEIL](https://www.tamtam.ai/c/irh-ingenieur-conseil) (anteagroup.fr)<br>International engineering and environmental consulting firm serving diverse clients worldwide with expertise in environmental solutions and sustainable development. | Environmental Services | 🇫🇷 Ludres | 261 |  |
| 99 | [Soprema Group](https://www.tamtam.ai/c/soprema-group) (soprema.com)<br>global construction materials manufacturer, specializing in waterproofing solutions, with extensive operations worldwide, including manufacturing, subsidiaries, and distribution channels across numerous countries | Wholesale Building Materials | 🇫🇷 Strasbourg | 260 | 1908 |
| 100 | [Polycea](https://www.tamtam.ai/c/polycea) (polyconseil.fr)<br>Offers comprehensive digital transformation support to clients, developing high-value technical solutions and ambitious, state-of-the-art systems for various organizations. | IT Services and IT Consulting | 🇫🇷 Paris | 252 | 1989 |

## How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 12, 2026.

## More company lists in Grand Est

- [The largest companies in Grand Est](https://www.tamtam.ai/l/largest-companies-grand-est) (5,706)
- [Multinational companies in Grand Est](https://www.tamtam.ai/l/multinational-companies-grand-est) (788)
- [Manufacturers in Grand Est](https://www.tamtam.ai/l/manufacturers-grand-est) (573)
- [Retail chains in Grand Est](https://www.tamtam.ai/l/retail-chains-grand-est) (530)
- [Public sector organisations in Grand Est](https://www.tamtam.ai/l/public-sector-organisations-grand-est) (427)
- [Family-owned companies in Grand Est](https://www.tamtam.ai/l/family-owned-companies-grand-est) (365)
- [Hardware manufacturers in Grand Est](https://www.tamtam.ai/l/hardware-companies-grand-est) (342)
- [Professional services firms in Grand Est](https://www.tamtam.ai/l/professional-services-firms-grand-est) (316)
- [Distributors and wholesalers in Grand Est](https://www.tamtam.ai/l/distributors-and-wholesalers-grand-est) (307)
- [Critical infrastructure operators in Grand Est](https://www.tamtam.ai/l/critical-infrastructure-operators-grand-est) (259)
- [IT services companies in Grand Est](https://www.tamtam.ai/l/it-services-companies-grand-est) (248)
- [SaaS companies in Grand Est](https://www.tamtam.ai/l/saas-companies-grand-est) (216)
- [Education providers in Grand Est](https://www.tamtam.ai/l/education-companies-grand-est) (215)
- [IT Services and IT Consulting companies in Grand Est](https://www.tamtam.ai/l/it-services-and-it-consulting-companies-grand-est) (213)
- [Software Development companies in Grand Est](https://www.tamtam.ai/l/software-development-companies-grand-est) (211)
- [Healthcare providers in Grand Est](https://www.tamtam.ai/l/healthcare-providers-grand-est) (202)
- [Construction companies in Grand Est](https://www.tamtam.ai/l/construction-companies-grand-est) (196)
- [Contract manufacturers in Grand Est](https://www.tamtam.ai/l/contract-manufacturers-grand-est) (192)
- [Retail companies in Grand Est](https://www.tamtam.ai/l/retail-companies-grand-est) (169)
- [Government Administration companies in Grand Est](https://www.tamtam.ai/l/government-administration-companies-grand-est) (168)
- [Industrial Machinery Manufacturing companies in Grand Est](https://www.tamtam.ai/l/industrial-machinery-manufacturing-companies-grand-est) (166)
- [Consulting firms in Grand Est](https://www.tamtam.ai/l/consulting-firms-grand-est) (165)
- [Food and beverage companies in Grand Est](https://www.tamtam.ai/l/food-and-beverage-companies-grand-est) (161)
- [Wholesale companies in Grand Est](https://www.tamtam.ai/l/wholesale-companies-grand-est) (159)

## The same list elsewhere in France

- [Companies with in-house R&D in France](https://www.tamtam.ai/l/r-and-d-companies-france) (8,749)
- [Companies with in-house R&D in Île-de-France](https://www.tamtam.ai/l/r-and-d-companies-ile-de-france) (2,695)
- [Companies with in-house R&D in Auvergne-Rhône-Alpes](https://www.tamtam.ai/l/r-and-d-companies-auvergne-rhone-alpes) (1,460)
- [Companies with in-house R&D in Occitanie](https://www.tamtam.ai/l/r-and-d-companies-occitanie) (680)
- [Companies with in-house R&D in Provence-Alpes-Côte d'Azur](https://www.tamtam.ai/l/r-and-d-companies-provence-alpes-cote-dazur) (612)
- [Companies with in-house R&D in Nouvelle-Aquitaine](https://www.tamtam.ai/l/r-and-d-companies-nouvelle-aquitaine) (566)
- [Companies with in-house R&D in the Hauts-de-Seine department](https://www.tamtam.ai/l/r-and-d-companies-hauts-de-seine) (510)
- [Companies with in-house R&D in the Rhône department](https://www.tamtam.ai/l/r-and-d-companies-rhone) (509)
- [Companies with in-house R&D in Pays de la Loire](https://www.tamtam.ai/l/r-and-d-companies-pays-de-la-loire) (480)
- [Companies with in-house R&D in Hauts-de-France](https://www.tamtam.ai/l/r-and-d-companies-hauts-de-france) (410)
- [Companies with in-house R&D in Brittany](https://www.tamtam.ai/l/r-and-d-companies-brittany) (366)
- [Companies with in-house R&D in the Haute-Garonne department](https://www.tamtam.ai/l/r-and-d-companies-haute-garonne) (323)
- [Companies with in-house R&D in the Bouches-du-Rhône department](https://www.tamtam.ai/l/r-and-d-companies-bouches-du-rhone) (320)
- [Companies with in-house R&D in the Isère department](https://www.tamtam.ai/l/r-and-d-companies-isere) (304)
- [Companies with in-house R&D in Bourgogne-Franche-Comté](https://www.tamtam.ai/l/r-and-d-companies-bourgogne-franche-comte) (261)
- [Companies with in-house R&D in the Nord department](https://www.tamtam.ai/l/r-and-d-companies-nord) (237)
- [Companies with in-house R&D in Normandy](https://www.tamtam.ai/l/r-and-d-companies-normandy) (227)
- [Companies with in-house R&D in the Gironde department](https://www.tamtam.ai/l/r-and-d-companies-gironde) (225)
- [Companies with in-house R&D in the Loire-Atlantique department](https://www.tamtam.ai/l/r-and-d-companies-loire-atlantique) (207)
- [Companies with in-house R&D in the Essonne department](https://www.tamtam.ai/l/r-and-d-companies-essonne) (198)
- [Companies with in-house R&D in Centre-Val de Loire](https://www.tamtam.ai/l/r-and-d-companies-centre-val-de-loire) (195)
- [Companies with in-house R&D in Paris](https://www.tamtam.ai/l/r-and-d-companies-paris) (1,249)
- [Companies with in-house R&D in Lyon](https://www.tamtam.ai/l/r-and-d-companies-lyon) (192)
- [Companies with in-house R&D in Toulouse](https://www.tamtam.ai/l/r-and-d-companies-toulouse) (172)

## The same list elsewhere

- [Companies with in-house R&D in the world](https://www.tamtam.ai/l/r-and-d-companies-in-the-world) (34,346)
- [Companies with in-house R&D in Europe](https://www.tamtam.ai/l/r-and-d-companies-in-europe) (20,169)

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Source: https://www.tamtam.ai/l/r-and-d-companies-grand-est