These are some of the largest companies with in-house R&D in Israel. The list includes a mix of established corporations and younger tech firms, predominantly in the software development, higher education, and defense sectors. Notable companies include Teva Pharmaceuticals, a global pharmaceutical company; Wix, offering customizable website creation; IAI - Israel Aerospace Industries, developing advanced defense systems; and Mobileye, a leader in autonomous driving technologies.
A significant pattern observed is the strong presence of higher education institutions, with The Hebrew University of Jerusalem, Technion, Bar-Ilan University, and University of Haifa all appearing among the largest R&D employers. This highlights the foundational role of academic research and development in Israel's innovation landscape. The majority of these companies and institutions are headquartered in or around Tel Aviv and Haifa.
| # | Company | Employees | |||
|---|---|---|---|---|---|
| 1 |
Teva Pharmaceuticalstevapharm.com
A global pharmaceutical company with a century of experience, developing and producing 3,500 medicines across various therapeutic areas for millions worldwide |
30,163 | |||
| 2 | 7,324 | ||||
| 3 |
The Hebrew University of Jerusalemnew.huji.ac.il
Leading Israeli university with over 23,000 students across undergraduate, master's, and doctoral programs, operating from four campuses in Jerusalem and Rehovot Alumni network available |
5,931 | |||
| 4 |
Technion - Israel Institute of Technologytechnion.ac.il
Global pioneer in scientific and technological education and research, it drives innovation in fields like biotechnology and nanotechnology, shaping the 'Startup Nation' and impacting millions worldwide. |
5,772 | |||
| 5 |
IAI - Israel Aerospace Industriesiai.co.il
Develops and manufactures advanced systems for air, space, sea, land, cyber and security, including satellites, missiles, unmanned aircraft, radars, and commercial aviation conversions. |
5,054 | |||
| 6 |
Bar-Ilan Universitybiu.ac.il
Leading university specializing in energy, sustainability, medical sciences, cyber, nanotechnology, natural language processing, community clinics, and student well-being. |
4,006 | |||
| 7 |
monday.commonday.com
It provides a low code-no code platform for organizations to create customized work management tools, enhancing team collaboration and transparency. |
3,848 | |||
| 8 |
Mobileyemobileye.com
Leader in autonomous driving and driver-assist technologies, specializing in computer vision, machine learning, mapping, and data analysis for self-driving vehicles and mobility solutions |
3,778 | |||
| 9 |
Sheba Medical Center, Tel Hashomersheba-global.com
A leading healthcare facility in the Middle East, committed to sharing knowledge and expertise globally to improve healthcare standards worldwide |
3,357 | |||
| 10 |
University of Haifahaifa.ac.il
The University of Haifa offers personalized attention and freedom for students to succeed, making a positive impact in various fields globally |
3,099 | |||
| 11 |
SolarEdge Technologiessolaredge.com
Develops smart energy solutions for solar power optimization, battery storage, EV charging, home energy management, and uninterrupted power supply for various market segments. |
3,067 | |||
| 12 |
Playtikaplaytika.com
A pioneering digital entertainment company reshaping the gaming landscape with cutting-edge technologies, data-driven insights, and creative storytelling in casual games |
2,855 | |||
| 13 |
Rafael Advanced Defense Systemsrafael.co.il
Pioneering technological defense solutions for air, land, sea, space, and cyber domains through extensive operational experience and global industrial cooperation programs worldwide. |
2,567 | |||
| 14 |
ADAMA Ltd.adama.com
Global provider of diverse, high-quality crop protection products and solutions to control weeds, insects, diseases, and improve yields worldwide. |
2,420 | |||
| 15 |
Reichman Universityruni.ac.il
Leading educational institution in Israel offering interdisciplinary programs for future leaders in business, law, technology, communications, economics, and more |
2,266 | |||
| 16 |
Elbit Systemselbitsystems.com
Develops, manufactures, integrates and sustains next-generation defense solutions across multiple domains, leveraging Israel's technology ecosystem to address evolving battlefield challenges and threats. |
2,240 | |||
| 17 | 2,199 | ||||
| 18 |
Rambam Health Care Campusrambam.org.il
Leading hospital in Northern Israel, offering a wide range of healthcare services, specialized in trauma treatment, oncology, neurosurgery, and pediatric care |
2,077 | |||
| 19 |
Moon Activemoonactive.com
A rapidly expanding mobile game company creating enjoyable entertainment for players worldwide |
1,920 | |||
| 20 |
Netafimnetafim.com
Global leader in precision agriculture solutions, pioneering drip irrigation technology, offering end-to-end solutions for sustainable farming practices worldwide |
1,914 | |||
| 21 |
Stratasysstratasys.com
Stratasys offers industrial-grade additive solutions to address design and manufacturing challenges throughout the production cycle, pushing boundaries in a changing world |
1,896 | |||
| 22 |
ELTA Systems Ltdiai.co.il
Develops and manufactures advanced defense solutions specializing in electromagnetic sensors, radar, electronic warfare, communication systems, and cyber intelligence for global security forces. |
1,853 | |||
| 23 |
Nova Ltd.novami.com
Innovative provider of advanced metrology solutions for semiconductor manufacturing, enhancing process performance, yields, and time to market for global IC manufacturers |
1,783 | |||
| 24 |
Tel Aviv Medical Centertasmc.org.il
Leading healthcare institution in Israel, integrating clinical care with research to develop new medical understanding and treatment modalities through numerous research projects |
1,666 | |||
| 25 |
Radwareradware.com
Global leader in application security and delivery solutions for multi-cloud environments, utilizing AI-driven algorithms for real-time protection against web, application, DDoS attacks, API abuse, and bad bots. |
1,582 | |||
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| 26 |
Cognytecognyte.com
Global leader in investigative analytics software empowering organizations with actionable intelligence for security, investigations, threat mitigation, and decision-making |
1,564 | |||
| 27 |
Tower Semiconductortowersemi.com
Manufacturing analog integrated circuits for communication, automotive, medical, industrial, consumer, IoT, aerospace, defense markets worldwide. |
1,501 | |||
| 28 |
Rivulis Irrigationrivulis.com
Global leader providing innovative micro-irrigation solutions for seasonal, permanent, and protected crops to promote a sustainable agri-food supply chain. |
1,496 | |||
| 29 |
AudioCodesaudiocodes.com
A leading vendor providing advanced voice networking and media processing solutions for unified communications, contact centers, and hosted business services globally |
1,427 | |||
| 30 |
Plariumcompany.plarium.com
Global gaming developer since 2009, specializing in mobile and social games with over 480 million users worldwide and a focus on player engagement and community building |
1,323 | |||
| 31 |
רפאל מערכות לחימה מתקדמות - קריירהrafael.co.il
A leading defense systems provider specializing in high-tech solutions for air, land, sea, and space applications with strong international partnerships |
1,156 | |||
| 32 |
Tnuvatnuva.co.il
Leading consumer goods producer manufacturing dairy, frozen foods, and meat while supporting local agriculture through extensive distribution networks and foodtech innovation hubs. |
1,151 | |||
| 33 |
ISCAR Headquartersiscar.com
A leading producer of innovative cutting tools for metalworking, offering a wide range of solutions such as turning, milling, and threading tools |
1,101 | |||
| 34 | 1,080 | ||||
| 35 | 1,068 | ||||
| 36 |
3M Electronic Monitoring Ltd.3m.com
Global leader specializing in GPS, RF, and Alcohol monitoring technology for the criminal justice market, with a focus on offender supervision worldwide |
995 | |||
| 37 |
Shaare Zedek Medical Center, Jerusalemszmc.org.il
A leading medical center in Jerusalem, providing advanced and compassionate care to over 650,000 patients annually, while also conducting extensive scientific research efforts |
932 | |||
| 38 | 907 | ||||
| 39 | 893 | ||||
| 40 |
Ex Librisexlibrisgroup.com
Provides cloud-based software for managing and discovering library materials and mobile campus solutions to enhance student engagement and success at academic institutions globally. |
860 | |||
| 41 |
DRS RADA Technologiesdrsrada.com
Specializing in radar solutions and avionics, this company operates under Leonardo DRS to provide proprietary technology and legacy systems |
804 | |||
| 42 |
Shenkar - Engineering. Design. Art.shenkar.ac.il
A leading academic institution in Israel, offering multidisciplinary programs in engineering, design, and art at the undergraduate and graduate levels |
748 | |||
| 43 |
Kornit Digitalkornit.com
Global provider of sustainable digital printing systems, inks, consumables, and workflow management for on-demand fashion and textile production. |
731 | |||
| 44 |
Hazera Seedshazera.com
Breeds, develops, produces, and markets a wide range of vegetable crop varieties and seeds globally, focusing on innovation and grower support through extensive research. |
699 | |||
| 45 |
Camtekcamtek.com
Leading manufacturer of metrology and inspection equipment, providing software solutions for the Semiconductors industry, offering yield-enhancement data and expert customer support globally |
689 | |||
| 46 |
Beilinson - Rabin Medical Center
Prominent and largest medical facility in Israel, known for high-quality medical care, research, and technological advancements with a focus on patient well-being |
670 | |||
| 47 |
Maytronicsmaytronics.com
Leader in innovative pool cleaning solutions, specializing in robotic pool cleaners, pool safety products, and water treatment kits, with a worldwide customer base |
656 | |||
| 48 |
Alma Lasersalmalasers.com
A global innovator in medical aesthetics, specializing in laser, light-based, radiofrequency, and ultrasound technologies to provide safe and effective treatments worldwide |
640 | |||
| 49 |
IDE Technologieside-tech.com
A global leader in water treatment solutions, specializing in developing, engineering, constructing, and operating desalination and industrial water treatment plants with a focus on partnership and innovation |
627 | |||
| 50 |
Tama Grouptama.co.il
A leading producer of agricultural solutions with modern technology, rooted in farming values, employing thousands globally for 70 years |
602 | |||
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How this list is built
Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 12, 2026.
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