# List of companies with in-house R&D in Karlsruhe

Tamtam tracks 25 companies with in-house R&D headquartered in Karlsruhe. This list ranks all of them by number of employees on LinkedIn, led by EnBW Energie Baden-Württemberg AG, IONOS and Karlsruhe University of Applied Sciences. Their median headcount is 353. Half of them were founded in 1986 or later.

These Karlsruhe-based companies with in-house R&D are primarily large and mid-sized firms in the IT, manufacturing, and research sectors. EnBW Energie Baden-Württemberg AG, with 27,000 employees, supplies energy. IONOS offers web presence and cloud solutions, while PTV GROUP develops software for transport planning. PI (Physik Instrumente) Group specializes in precision positioning technology. Chaos develops design and visualization technology, and Bruker AXS provides analytical X-ray systems.

The data shows a strong presence of research institutions and technology-focused companies, indicating a concentration on scientific and engineering advancements. Many of these companies were founded in the 1970s and 1980s, suggesting a mature R&D landscape in the region.

🇩🇪 Karlsruhe · 25 companies · Updated Nov 12, 2026

| # | Company | Industry | Headquarters | Employees | Founded |
|---|---|---|---|---|---|
| 1 | [EnBW Energie Baden-Württemberg AG](https://www.tamtam.ai/c/enbw-energie-baden-wurttemberg-ag) (enbw.com)<br>A leading energy supply company in Germany and Europe with a workforce of 20,000, providing electricity, gas, water, and energy-related products and services to 55 million customers | Utilities | 🇩🇪 Karlsruhe | 27,000 |  |
| 2 | [IONOS](https://www.tamtam.ai/c/ionos) (ionos.com)<br>Leading digitalization partner serving millions of SMBs across Europe and North America, offering web presence, productivity solutions, e-commerce tools, online marketing, and cloud solutions | IT Services and IT Consulting | 🇩🇪 Karlsruhe | 2,812 | 1988 |
| 3 | [Karlsruhe University of Applied Sciences](https://www.tamtam.ai/c/karlsruhe-university-of-applied-sciences) (h-ka.de)<br>A leading university offering programs in engineering, computer science, business, and media disciplines with a strong focus on teaching, research, and scientific further education | Higher Education | 🇩🇪 Karlsruhe | 1,041 | 1878 |
| 4 | [PTV GROUP](https://www.tamtam.ai/c/ptv-group) (ptvgroup.com)<br>Develops and optimizes software solutions for transport planning, logistics, traffic management, and mobility-as-a-service, improving movement of people and goods. | IT Services and IT Consulting | 🇩🇪 Karlsruhe | 970 | 1979 |
| 5 | [PI (Physik Instrumente) Group](https://www.tamtam.ai/c/pi-physik-instrumente-group) (physikinstrumente.com)<br>A global leader in precision positioning technology, developing high-quality products with piezo or motor drives, backed by over 40 years of experience and 200 technology patents | Manufacturing | 🇩🇪 Karlsruhe | 928 | 1970 |
| 6 | [Chaos](https://www.tamtam.ai/c/chaos) (chaos.com)<br>Development of design and visualization technology for architecture, engineering, construction, product design, manufacturing, and media industries worldwide. | Software Development | 🇩🇪 Karlsruhe | 922 | 1997 |
| 7 | [Bruker AXS](https://www.tamtam.ai/c/bruker-axs) (bruker.com)<br>Global provider of advanced analytical X-ray systems for a wide range of industries, offering innovative solutions for research and industrial applications | Appliances, Electrical, and Electronics Manufacturing | 🇩🇪 Karlsruhe | 700 | 1997 |
| 8 | [alfatraining Bildungszentrum GmbH](https://www.tamtam.ai/c/alfatraining-bildungszentrum-gmbh) (alfatraining.de)<br>This education center offers professional training in various fields, utilizing their in-house virtual learning platform to teach courses locally or remotely | Professional Training and Coaching | 🇩🇪 Karlsruhe | 663 | 2005 |
| 9 | [ROMACO GROUP](https://www.tamtam.ai/c/romaco-group) (romaco.com)<br>Global leader in packing and process technology, specializing in intelligent system solutions for the pharmaceutical industry, offering a range of equipment for various packaging needs | Machinery Manufacturing | 🇩🇪 Karlsruhe | 567 |  |
| 10 | [INIT Group](https://www.tamtam.ai/c/init-group) (initse.com)<br>Leading provider of integrated systems for public transport, specializing in planning, dispatching, telematics, and ticketing to enhance efficiency and attractiveness of services | IT Services and IT Consulting | 🇩🇪 Karlsruhe | 415 | 1983 |
| 11 | [Fraunhofer IOSB](https://www.tamtam.ai/c/fraunhofer-iosb) (iosb.fraunhofer.de)<br>This company develops innovative cameras, optimizes sensor use, processes data streams for decision support systems, and applies technology in various fields | Research Services | 🇩🇪 Karlsruhe | 402 | 1956 |
| 12 | [Fraunhofer Institute for Systems and Innovation Research ISI](https://www.tamtam.ai/c/fraunhofer-institute-for-systems-and-innovation-research-isi) (isi.fraunhofer.de)<br>The institute analyzes innovation origins and impacts, researches technology impacts on society, and provides recommendations for industry, politics, and science | Research Services | 🇩🇪 Karlsruhe | 401 | 1972 |
| 13 | [Chrono24](https://www.tamtam.ai/c/chrono24) (chrono24.com)<br>Leading online marketplace for luxury watches with over 500,000 timepieces from 35,000 sellers worldwide, offering a secure platform for enthusiasts | Retail Luxury Goods and Jewelry | 🇩🇪 Karlsruhe | 353 | 2003 |
| 14 | [IPG Automotive](https://www.tamtam.ai/c/ipg-automotive) (ipg-automotive.com)<br>Global leader in virtual test driving technology, providing innovative simulation solutions for vehicle development in areas such as Autonomous Vehicles, ADAS, Powertrain, and Vehicle Dynamics | Software Development | 🇩🇪 Karlsruhe | 348 | 1984 |
| 15 | [PTV Logistics](https://www.tamtam.ai/c/ptv-logistics) (ptvlogistics.com)<br>Offers innovative software solutions for logistics providers, focusing on route optimization to enhance efficiency, reduce costs, and promote sustainability. | Software Development | 🇩🇪 Karlsruhe | 347 | 1979 |
| 16 | [Gameforge](https://www.tamtam.ai/c/gameforge) (corporate.gameforge.com)<br>Gameforge is a leading Western publisher of MMO and Browser-based game titles, creating engaging experiences for players worldwide through quality content and community management | Computer Games | 🇩🇪 Karlsruhe | 306 | 2003 |
| 17 | [aluplast GmbH](https://www.tamtam.ai/c/aluplast-gmbh) (aluplast.net)<br>A dynamic international manufacturer of window profile systems, known for innovation, high performance, and reliability with a global presence and focus on environmental protection | Construction | 🇩🇪 Karlsruhe | 306 | 1982 |
| 18 | [CAS Software AG](https://www.tamtam.ai/c/cas-software-ag) (cas.de)<br>It provides innovative CRM solutions for small and medium-sized enterprises, focusing on customer relationships and integration with existing software. | Software Development | 🇩🇪 Karlsruhe | 305 | 1986 |
| 19 | [Asseco Solutions DACH](https://www.tamtam.ai/c/asseco-solutions-dach) (applus-erp.de)<br>A German-based software company offering business solutions, led by experienced executives and committed to transparency and compliance with legal requirements | Software Development | 🇩🇪 Karlsruhe | 294 | 1993 |
| 20 | [Dr. Willmar Schwabe Business Services GmbH & Co. KG](https://www.tamtam.ai/c/schwabe-group) (schwabe-group.com)<br>Researching, developing, and producing plant-based medicines and health products, aiming for market leadership in phytomedicines globally for sustainable, productive, and healthy lives. | Pharmaceutical Manufacturing | 🇩🇪 Karlsruhe | 284 | 1866 |
| 21 | [Disy Informationssysteme GmbH](https://www.tamtam.ai/c/disy-informationssysteme-gmbh) (disy.net)<br>A software company specializing in data analysis and management solutions for large organizations, integrating spatial and non-spatial data with innovative products | Software Development | 🇩🇪 Karlsruhe | 143 | 1997 |
| 22 | [STARFACE GmbH](https://www.tamtam.ai/c/starface-gmbh) (starface.com)<br>Specializing in business communication solutions, we connect people in the digital workplace, emphasizing simplicity and digital innovation with a dynamic, flat-hierarchy culture | Telecommunications | 🇩🇪 Karlsruhe | 134 | 2005 |
| 23 | [Hitex GmbH](https://www.tamtam.ai/c/hitex-gmbh) (hitex.com)<br>A leading supplier of embedded solutions and development tools, offering consulting, support, and expertise in microcontrollers to integrate safety and security into applications quickly | Software Development | 🇩🇪 Karlsruhe | 47 | 1976 |
| 24 | [SPAES - Mission Equipment & Medical Systems](https://www.tamtam.ai/c/spaes-mission-equipment-and-medical-systems) (spaes-aviation.de)<br>Specializing in technical solutions for emergency medical systems in aviation, offering design, certification, and integration services for aircraft equipment and systems | Aviation and Aerospace Component Manufacturing | 🇩🇪 Karlsruhe | 17 | 2014 |
| 25 | [shonDynamics GmbH](https://www.tamtam.ai/c/shondynamics-gmbh) (shondynamics.de)<br>Simplifying complex fluid dynamics problems for engineers using proprietary solvers to provide accurate results quickly, focusing on interactions of solid bodies and fluids | Software Development | 🇩🇪 Karlsruhe | 11 | 2018 |

## How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 12, 2026.

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Source: https://www.tamtam.ai/l/r-and-d-companies-karlsruhe
