# List of companies with in-house R&D in Lazio
Tamtam tracks 120 companies with in-house R&D headquartered in Lazio. This list ranks the 50 largest by number of employees on LinkedIn, led by Leonardo, Eni and Enel Group. Their median headcount is 1,038. Half of them were founded in 1979 or later. The most common headquarters are Rome (43).
These large companies in Lazio, primarily headquartered in Rome, represent a diverse range of sectors with a strong emphasis on research and development. Key players include Leonardo, a defense and security multinational, and Eni, an integrated energy business. Enel Group focuses on electricity operations, while Ferrovie dello Stato Italiane manages national rail infrastructure. Sapienza Universitร di Roma and Consiglio Nazionale delle Ricerche are prominent research institutions, and Engineering Group is a digital transformation company.
A notable pattern among these companies is their significant employee count, with many having tens of thousands of employees, indicating established, large-scale operations. The concentration of headquarters in Rome also highlights the city as a central hub for these major Italian enterprises.
๐ฎ๐น Lazio ยท 50 companies ยท Updated Nov 11, 2026
| # | Company | Industry | Headquarters | Employees | Founded |
|---|---|---|---|---|---|
| 1 | [Leonardo](https://www.tamtam.ai/c/leonardo) (leonardo.com)
Defense and security multinational company specializing in aerospace, cybersecurity, military systems, and advanced technology solutions | Defense and Space Manufacturing | ๐ฎ๐น Rome | 38,521 | 1948 |
| 2 | [Eni](https://www.tamtam.ai/c/eni) (eni.com)
Integrated energy business, decarbonized products, renewable and retail, bio-refineries, biomethane, low-carbon energy, mobility services. | Oil and Gas | ๐ฎ๐น Rome | 32,259 | |
| 3 | [Enel Group](https://www.tamtam.ai/c/enel-group) (enel.com)
Multinational company reshaping the future of energy, a leading integrated electricity operator. Distributes and supplies electricity to millions of end users. | Utilities | ๐ฎ๐น Rome | 31,218 | 1962 |
| 4 | [Ferrovie dello Stato Italiane S.p.A.](https://www.tamtam.ai/c/ferrovie-dello-stato-italiane-s-p-a) (fsitaliane.it)
National rail infrastructure management, passenger transport services, logistics solutions, and urban regeneration projects across Italy. | Facilities Services | ๐ฎ๐น Rome | 28,071 | |
| 5 | [Sapienza Universitร di Roma](https://www.tamtam.ai/c/sapienza-universita-di-roma) (uniroma1.it)
A prestigious, historic university in Rome with a diverse range of academic programs, research opportunities, and international exchange programs for students and academics | Research Services | ๐ฎ๐น Rome | 16,981 | 1303 |
| 6 | [Engineering Group](https://www.tamtam.ai/c/engineering-group) (eng.it)
Leading digital transformation company with global presence, specializing in innovation, proprietary solutions, R&D, and diverse market expertise. | IT Services and IT Consulting | ๐ฎ๐น Rome | 11,815 | 1980 |
| 7 | [Consiglio Nazionale delle Ricerche](https://www.tamtam.ai/c/consiglio-nazionale-delle-ricerche) (cnr.it)
A public organization in Italy that conducts and promotes interdisciplinary research in various sectors for scientific, technological, and social development | Research Services | ๐ฎ๐น Rome | 6,744 | 1923 |
| 8 | [Terna SpA](https://www.tamtam.ai/c/terna-spa) (terna.it)
An Italian energy transmission grid operator focused on ensuring the safety, quality, and cost-effectiveness of the electricity system while promoting sustainability and innovation | Utilities | ๐ฎ๐น Rome | 5,058 | 1999 |
| 9 | [INAIL, Istituto Nazionale Assicurazione contro gli Infortuni sul Lavoro](https://www.tamtam.ai/c/inail-istituto-nazionale-assicurazione-contro-gli-infortuni-sul-lavoro) (inail.it)
A public non-profit entity founded in 1883, provides insurance for all workers against work-related accidents, disabilities, health damage, and occupational diseases Additionally, supports injured workers with rehabilitation and reintegration assistance | Government Administration | ๐ฎ๐น Rome | 4,031 | 1883 |
| 10 | [Fondazione Policlinico Universitario Agostino Gemelli IRCCS](https://www.tamtam.ai/c/fondazione-policlinico-universitario-agostino-gemelli-irccs) (policlinicogemelli.it)
A leading Italian hospital specializing in personalized medicine, innovative biotechnologies, and clinical care for a wide range of specialties, including oncology and rare diseases | Hospitals and Health Care | ๐ฎ๐น Rome | 3,810 | |
| 11 | [Telespazio](https://www.tamtam.ai/c/telespazio) (telespazio.com)
Provides comprehensive space services, from system design to satellite control, Earth observation, communication, and navigation, utilizing AI for advanced applications improving life and addressing climate change. | Defense and Space Manufacturing | ๐ฎ๐น Rome | 2,864 | 1961 |
| 12 | [ENEA](https://www.tamtam.ai/c/enea) (enea.it)
An Italian organization specialized in research, development, and promotion of technologies for energy efficiency, renewable sources, nuclear energy, environmental protection, and more | Research Services | ๐ฎ๐น Rome | 2,659 | |
| 13 | [INFN](https://www.tamtam.ai/c/infn) (infn.it)
An Italian research organization specializing in subnuclear, nuclear, and astroparticle physics, developing advanced technologies and collaborating with industry and academia | Research Services | ๐ฎ๐น Rome | 2,332 | 1951 |
| 14 | [Translated](https://www.tamtam.ai/c/translated) (translated.com)
A leading provider of human translation services in 150+ languages, combining human creativity and machine intelligence for speedy, high-quality translations | Translation and Localization | ๐ฎ๐น Rome | 2,070 | 1999 |
| 15 | [Angelini Pharma](https://www.tamtam.ai/c/angelini-pharma) (angelinipharma.com)
A pharmaceutical company dedicated to developing new medicines and solutions for patients, with a focus on CNS, mental health, and consumer health | Pharmaceutical Manufacturing | ๐ฎ๐น Rome | 2,043 | 1919 |
| 16 | [ELT Group](https://www.tamtam.ai/c/elt-group) (eltgroup.net)
A global leader in electronic defense systems, specializing in managing the electromagnetic spectrum and offering technology solutions for defense, cyber, space, and biodefense | Defense and Space Manufacturing | ๐ฎ๐น Rome | 1,728 | 1951 |
| 17 | [Yokohama TWS](https://www.tamtam.ai/c/yokohama-tws) (yokohama-tws.com)
A global leader in sustainable tire and wheel solutions for various industries, focusing on innovation, technology, and environmental responsibility | Industrial Machinery Manufacturing | ๐ฎ๐น Villa Adriana (Tivoli) - Rome | 1,680 | |
| 18 | [Angelini Industries](https://www.tamtam.ai/c/angelini-industries) (angeliniindustries.com)
Operates globally in health, industrial technology, and consumer goods sectors, focusing on growth, R&D, environmental impact reduction, and worker safety. | Manufacturing | ๐ฎ๐น Rome | 2,855 | |
| 19 | [BSP Pharmaceuticals S.p.A.](https://www.tamtam.ai/c/bsp-pharmaceuticals-s-p-a) (bsppharmaceuticals.com)
A contract development and manufacturing organization specializing in producing cytotoxic, high potent oncology drugs, innovative compounds, peptides, proteins, oligonucleotides, and nano medicines | Pharmaceutical Manufacturing | ๐ฎ๐น Latina Scalo | 1,413 | 2006 |
| 20 | [Italtel](https://www.tamtam.ai/c/italtel) (italtel.com)
The company provides communication technology solutions, integrates traditional and new technologies, offers managed services, and focuses on sustainability and inclusivity | Telecommunications | ๐ฎ๐น Rome | 1,398 | 1921 |
| 21 | [AVIO](https://www.tamtam.ai/c/avio) (avio.com)
A leading space propulsion company near Rome, Italy, offering competitive solutions for launching payloads into Earth orbit through Vega rockets | Aviation and Aerospace Component Manufacturing | ๐ฎ๐น Colleferro | 1,254 | 1912 |
| 22 | [CREA Ricerca](https://www.tamtam.ai/c/crea-ricerca) (crea.gov.it)
Leading Italian research organization focused on agri-food supply chains Innovative and sustainable solutions in agriculture, livestock, food science, and socio-economics Promoting circular economy and consumer protection | Research Services | ๐ฎ๐น Rome | 1,128 | 2015 |
| 23 | [KT - Kinetics Technology](https://www.tamtam.ai/c/kt-kinetics-technology) (kt-met.com)
Specialized EPC Contractor for refining industry, offering integrated engineering solutions with focus on process design, licensing, sulphur recovery, and hydrogen/syngas production | Oil and Gas | ๐ฎ๐น Rome | 1,088 | 1971 |
| 24 | [Daikin Applied Europe](https://www.tamtam.ai/c/daikin-applied-europe) (daikinapplied.eu)
Multinational company manufacturing components for hydronic HVAC systems with premium quality, reliability, and efficiency, leading development, manufacturing, and sale in Europe, Middle East, and Africa | Machinery Manufacturing | ๐ฎ๐น Ariccia | 1,056 | 1968 |
| 25 | [Istituto Poligrafico e Zecca dello Stato (IPZS)](https://www.tamtam.ai/c/istituto-poligrafico-e-zecca-dello-stato-ipzs) (ipzs.it)
The company protects citizens' physical and digital identities, secures sensitive data, ensures production reliability, and enhances cultural heritage through tailored solutions and products | Printing Services | ๐ฎ๐น Rome | 1,038 | 1928 |
| 26 | [Universitร degli Studi di Cassino e del Lazio Meridionale](https://www.tamtam.ai/c/universita-degli-studi-di-cassino-e-del-lazio-meridionale) (unicas.it)
The University offers a wide range of undergraduate and graduate programs, including courses in English, joint degrees with foreign universities, postgraduate opportunities, and various campus facilities | Research Services | ๐ฎ๐น Cassino | 1,002 | 1979 |
| 27 | [San Raffaele](https://www.tamtam.ai/c/san-raffaele) (sanraffaele.it)
A leading healthcare organization providing excellence in research, rehabilitation, and patient care with a network of facilities and specialists across Italy | Hospitals and Health Care | ๐ฎ๐น Rome | 944 | |
| 28 | [Universitร degli Studi Niccolรฒ Cusano](https://www.tamtam.ai/c/universita-degli-studi-niccolo-cusano) (unicusano.it)
An online university established in 2006, with a campus in Rome including dorms, sports facilities, a theater, and a Medical-Scientific Research Center | Higher Education | ๐ฎ๐น Rome | 922 | 2006 |
| 29 | [Istituto Nazionale di Geofisica e Vulcanologia](https://www.tamtam.ai/c/istituto-nazionale-di-geofisica-e-vulcanologia) (ingv.it)
The company specializes in monitoring geophysical phenomena, such as seismic activity and volcanic eruptions, in Italy through advanced instrumentation and collaboration with universities and research institutions | Research Services | ๐ฎ๐น Rome | 916 | 1841 |
| 30 | [Amplia Infrastructures](https://www.tamtam.ai/c/amplia-infrastructures) (ampliaspa.it)
A construction company specializing in roads, motorways, bridges, airports, and road surface materials International presence in Eastern Europe, Middle East, and South America | Construction | ๐ฎ๐น Rome | 891 | |
| 31 | [Topnetwork S.p.A.](https://www.tamtam.ai/c/topnetwork-s-p-a) (topnetwork.it)
A service agency supporting digital transformation with innovative solutions, integrating AI, blockchain, Cloud, Data Science, IoT, robotics, and more | IT Services and IT Consulting | ๐ฎ๐น Rome | 836 | 2003 |
| 32 | [Fondazione Santa Lucia](https://www.tamtam.ai/c/fondazione-santa-lucia) (fondazionesantalucia.it)
Specializing in neurorehabilitation, the organization provides autonomy and quality of life for adults and children through research and high levels of care | Hospitals and Health Care | ๐ฎ๐น Rome | 823 | 1960 |
| 33 | [INAF Istituto Nazionale di Astrofisica](https://www.tamtam.ai/c/inaf-istituto-nazionale-di-astrofisica) (inaf.it)
The company promotes, coordinates, and conducts research in Astronomy, Radioastronomy, Space Astrophysics, and Cosmic Physics It also promotes astronomy education in schools and society | Research Services | ๐ฎ๐น Rome | 777 | 1999 |
| 34 | [SEKO](https://www.tamtam.ai/c/seko) (seko.com)
Global manufacturer specializing in peristaltic pumps, dosing pumps, dosing skids, and control instruments for various industries in over 120 countries | Industrial Machinery Manufacturing | ๐ฎ๐น Santa Rufina | 702 | 1976 |
| 35 | [Sogin](https://www.tamtam.ai/c/sogin) (sogin.it)
Italian state-owned organization managing nuclear site decontamination, radioactive waste, and decommissioning projects for power plants, research centers, and repositories | Oil and Gas | ๐ฎ๐น Rome | 696 | 1999 |
| 36 | [MSD Italia](https://www.tamtam.ai/c/msd-italia) (msd-italia.it)
A multinational pharmaceutical leader dedicated to discovering innovative products and services to save and improve patients' lives worldwide | Pharmaceutical Manufacturing | ๐ฎ๐น Rome | 598 | |
| 37 | [Universitร degli Studi Guglielmo Marconi](https://www.tamtam.ai/c/universita-degli-studi-guglielmo-marconi) (unimarconi.it)
A world-class university offering innovative learning methodologies, interdisciplinary research, and programs to prepare students for global challenges with virtual labs and simulations | Higher Education | ๐ฎ๐น Rome | 562 | 2004 |
| 38 | [Fondazione Policlinico Universitario Campus Bio-Medico](https://www.tamtam.ai/c/fondazione-policlinico-universitario-campus-bio-medico) (policlinicocampusbiomedico.it)
A non-profit foundation focused on protecting and promoting human health through healthcare, education, scientific research, and innovation in biomedicine | Hospitals and Health Care | ๐ฎ๐น Rome | 536 | 1994 |
| 39 | [Gruppo Servizi Associati S.p.A.](https://www.tamtam.ai/c/gruppo-servizi-associati-s-p-a) (grupposerviziassociati.it)
A leading company in safety services with over 25 years of experience, offering fire prevention, rescue, and training services nationally and in Europe | Security and Investigations | ๐ฎ๐น Rome | 523 | 1999 |
| 40 | [University of Viterbo "La Tuscia"โ](https://www.tamtam.ai/c/university-of-viterbo-la-tuscia) (unitus.it)
Leader in research and teaching in various fields including agriculture, bio-science, economics, law, engineering, languages, and social studies in Italy | Higher Education | ๐ฎ๐น Viterbo | 491 | 1980 |
| 41 | [Eustema S.p.A.](https://www.tamtam.ai/c/eustema-s-p-a) (eustema.it)
A consulting and software engineering company in Italy, providing ICT solutions to public administrations and businesses in telecom, transportation, utilities, and services sectors | IT Services and IT Consulting | ๐ฎ๐น Rome | 466 | 1989 |
| 42 | [MOVYON](https://www.tamtam.ai/c/movyon) (movyon.com)
Design and implement smart, sustainable mobility solutions including infrastructure, traffic management, tolling, and smart city technologies for public and private sectors. | IT Services and IT Consulting | ๐ฎ๐น Rome | 457 | |
| 43 | [Takeda Italia](https://www.tamtam.ai/c/takeda-italia) (takeda.com)
Innovative healthcare company focused on gastroenterology and oncology, committed to advancing healthcare through new medicines and building a patient-centered model | Pharmaceutical Manufacturing | ๐ฎ๐น Rome | 449 | 1982 |
| 44 | [Tinexta Infocert](https://www.tamtam.ai/c/tinexta-infocert) (infocert.it)
It empowers customers' digital transformation with innovative solutions, ensuring trustworthiness, compliance, and sustainability across various sectors in Europe. | IT Services and IT Consulting | ๐ฎ๐น Rome | 443 | 2007 |
| 45 | [Intecs](https://www.tamtam.ai/c/intecs) (intecs.it)
International leader in design and development of applications, tools, software, hardware components and products for various critical markets including Aerospace, Defense, and Automotive. | Engineering Services | ๐ฎ๐น Rome | 413 | 1974 |
| 46 | [IDI IRCCS - Istituto Dermopatico dell'Immacolata](https://www.tamtam.ai/c/idi-irccs-istituto-dermopatico-dell-immacolata) (idi.it)
An Italian scientific research institute specializing in dermatology, providing high-quality inpatient and outpatient care with a multidisciplinary approach and expertise in rare skin diseases | Hospitals and Health Care | ๐ฎ๐น Rome | 392 | 1912 |
| 47 | [Almawave](https://www.tamtam.ai/c/almawave) (almawave.com)
Italian company specializing in Data and Artificial Intelligence. Offers proprietary technologies, solutions, services for digital evolution of companies and public administrations. | IT Services and IT Consulting | ๐ฎ๐น Rome | 369 | 2006 |
| 48 | [Deep Blue](https://www.tamtam.ai/c/deep-blue) (dblue.it)
A research and consultancy firm specializing in human-centred design and validation in various industries, offering services in human factors, safety, and sustainability | Research Services | ๐ฎ๐น Rome | 360 | 2001 |
| 49 | [GCF GENERALE COSTRUZIONI FERROVIARIE SPA](https://www.tamtam.ai/c/gcf-generale-costruzioni-ferroviarie-spa) (generalecostruzioniferroviarie.com)
A leader in railway infrastructure, electrification, and signaling with over 60 years of experience, strong presence in Europe and international markets, high productivity, safety, and quality standards | Railroad Equipment Manufacturing | ๐ฎ๐น Rome | 355 | 1950 |
| 50 | [Fondazione Telethon](https://www.tamtam.ai/c/fondazione-telethon) (fondazionetelethon.it)
Leading Italian biomedical charity advancing research for muscular dystrophies and genetic diseases through funding research projects from basic to clinical trials since 1990 | Research Services | ๐ฎ๐น Rome | 343 | 1990 |
## How this list is built
Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 11, 2026.
## More company lists in Lazio
- [The largest companies in Lazio](https://www.tamtam.ai/l/largest-companies-lazio) (1,243)
- [Multinational companies in Lazio](https://www.tamtam.ai/l/multinational-companies-lazio) (226)
- [Retail chains in Lazio](https://www.tamtam.ai/l/retail-chains-lazio) (128)
- [Critical infrastructure operators in Lazio](https://www.tamtam.ai/l/critical-infrastructure-operators-lazio) (105)
- [Public sector organisations in Lazio](https://www.tamtam.ai/l/public-sector-organisations-lazio) (102)
- [Financial services firms in Lazio](https://www.tamtam.ai/l/financial-services-firms-lazio) (98)
- [IT services companies in Lazio](https://www.tamtam.ai/l/it-services-companies-lazio) (84)
- [IT Services and IT Consulting companies in Lazio](https://www.tamtam.ai/l/it-services-and-it-consulting-companies-lazio) (78)
- [Manufacturers in Lazio](https://www.tamtam.ai/l/manufacturers-lazio) (77)
- [Companies with a mobile app in Lazio](https://www.tamtam.ai/l/companies-with-mobile-app-lazio) (75)
- [Financial Services companies in Lazio](https://www.tamtam.ai/l/financial-services-companies-lazio) (61)
- [Education providers in Lazio](https://www.tamtam.ai/l/education-companies-lazio) (60)
- [Consulting firms in Lazio](https://www.tamtam.ai/l/consulting-firms-lazio) (59)
- [Professional services firms in Lazio](https://www.tamtam.ai/l/professional-services-firms-lazio) (58)
- [Corporate groups and holding companies in Lazio](https://www.tamtam.ai/l/holding-companies-lazio) (51)
- [Software Development companies in Lazio](https://www.tamtam.ai/l/software-development-companies-lazio) (48)
- [Hospitality companies in Lazio](https://www.tamtam.ai/l/hospitality-companies-lazio) (46)
- [Family-owned companies in Lazio](https://www.tamtam.ai/l/family-owned-companies-lazio) (46)
- [Aerospace and defence companies in Lazio](https://www.tamtam.ai/l/aerospace-and-defense-companies-lazio) (45)
- [E-commerce companies in Lazio](https://www.tamtam.ai/l/ecommerce-companies-lazio) (45)
- [Hotel and hospitality groups in Lazio](https://www.tamtam.ai/l/hospitality-groups-lazio) (43)
- [Consumer goods companies in Lazio](https://www.tamtam.ai/l/consumer-goods-companies-lazio) (42)
- [Healthcare providers in Lazio](https://www.tamtam.ai/l/healthcare-providers-lazio) (42)
- [Luxury brands in Lazio](https://www.tamtam.ai/l/luxury-brands-lazio) (39)
## The same list elsewhere in Italy
- [Companies with in-house R&D in Italy](https://www.tamtam.ai/l/r-and-d-companies-italy) (1,418)
- [Companies with in-house R&D in Lombardy](https://www.tamtam.ai/l/r-and-d-companies-lombardy) (432)
- [Companies with in-house R&D in Emilia-Romagna](https://www.tamtam.ai/l/r-and-d-companies-emilia-romagna) (195)
- [Companies with in-house R&D in Veneto](https://www.tamtam.ai/l/r-and-d-companies-veneto) (182)
- [Companies with in-house R&D in Piedmont](https://www.tamtam.ai/l/r-and-d-companies-piedmont) (102)
- [Companies with in-house R&D in Tuscany](https://www.tamtam.ai/l/r-and-d-companies-tuscany) (80)
- [Companies with in-house R&D in Campania](https://www.tamtam.ai/l/r-and-d-companies-campania) (44)
- [Companies with in-house R&D in Friuli-Venezia Giulia](https://www.tamtam.ai/l/r-and-d-companies-friuli-venezia-giulia) (43)
- [Companies with in-house R&D in the Marche](https://www.tamtam.ai/l/r-and-d-companies-marche) (34)
- [Companies with in-house R&D in Apulia](https://www.tamtam.ai/l/r-and-d-companies-apulia) (26)
- [Companies with in-house R&D in Trentino-South Tyrol](https://www.tamtam.ai/l/r-and-d-companies-trentino-south-tyrol) (25)
- [Companies with in-house R&D in Milan](https://www.tamtam.ai/l/r-and-d-companies-milan) (124)
- [Companies with in-house R&D in Rome](https://www.tamtam.ai/l/r-and-d-companies-rome) (82)
- [Companies with in-house R&D in Turin](https://www.tamtam.ai/l/r-and-d-companies-turin) (31)
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Source: https://www.tamtam.ai/l/r-and-d-companies-lazio