# Top 30 companies with in-house R&D in Lyon

Tamtam tracks 192 companies with in-house R&D headquartered in Lyon. This list ranks the 30 largest by number of employees on LinkedIn, led by Hospices Civils de Lyon - HCL, Cegid and Université Lumière Lyon 2. Their median headcount is 667. Half of them were founded in 1973 or later.

These Lyon-based organizations with in-house R&D are primarily large groups and mid-sized firms, spanning diverse sectors from healthcare to industrial manufacturing and higher education. They include major institutions like Hospices Civils de Lyon, a public university hospital, and Cegid, a European leader in cloud management solutions. Université Lumière Lyon 2 and Université Jean Moulin are large public universities. Cerema is a public referent for territory development, and Gerflor produces innovative flooring and wallcovering.

A notable pattern among these companies is their strong presence in both public service and industrial sectors. Several organizations, such as Hospices Civils de Lyon, Université Lumière Lyon 2, and Cerema, are public or quasi-public entities. Concurrently, there is a significant cluster of manufacturing and industrial firms like Gerflor, Sicame Group, and KEM ONE, indicating a mixed economic landscape in Lyon.

🇫🇷 Lyon · 30 companies · Updated Nov 11, 2026

| # | Company | Industry | Headquarters | Employees | Founded |
|---|---|---|---|---|---|
| 1 | [Hospices Civils de Lyon - HCL](https://www.tamtam.ai/c/hospices-civils-de-lyon-hcl) (chu-lyon.fr)<br>Public university hospital provides care, education, research, medical innovation, prevention, and health education with over 22,000 professionals across 14 facilities. | Hospitals and Health Care | 🇫🇷 Lyon | 8,220 | 1796 |
| 2 | [Cegid](https://www.tamtam.ai/c/cegid) (cegid.com)<br>European leader cloud management solutions finance, HR, accounting, retail, and entrepreneurs. Offers tailored solutions for digital business transformation worldwide. | Software Development | 🇫🇷 Lyon | 4,896 |  |
| 3 | [Université Lumière Lyon 2](https://www.tamtam.ai/c/universite-lumiere-lyon-2) (univ-lyon2.fr)<br>Large French public university offering diverse programs from bachelor to doctorate, focusing on research, international partnerships, and societal engagement. | Higher Education | 🇫🇷 Lyon | 3,390 | 1973 |
| 4 | [Université Jean Moulin (Lyon III)](https://www.tamtam.ai/c/universite-jean-moulin-lyon-iii) (univ-lyon3.fr)<br>Public university offering multidisciplinary higher education and research in law, management, humanities, and social sciences with strong societal engagement. | Higher Education | 🇫🇷 Lyon | 2,461 | 1973 |
| 5 | [Cerema](https://www.tamtam.ai/c/cerema) (cerema.fr)<br>Public referent for territory development, assisting government, communities, and businesses in adapting areas to climate change across six activity domains. | Government Administration | 🇫🇷 Lyon | 2,160 | 2014 |
| 6 | [emlyon business school](https://www.tamtam.ai/c/emlyon-business-school) (em-lyon.com)<br>World-renowned business school offering higher education and continued education programs with a focus on skill hybridization, social responsibility, and impactful alumni worldwide | Education Administration Programs | 🇫🇷 Lyon | 2,101 |  |
| 7 | [Gerflor](https://www.tamtam.ai/c/gerflor) (gerflor.com)<br>Production and distribution of design-driven, innovative, environmentally-friendly flooring, wallcovering, and finishes across international healthcare, housing, education, sport, transport, retail, and industrial markets. | Wholesale Building Materials | 🇫🇷 Lyon | 2,037 | 1937 |
| 8 | [Sicame Group](https://www.tamtam.ai/c/sicame-group) (sicame-group.com)<br>World leader in production, sales of accessories and services for electrical energy transmission and distribution, safety equipment, and industrial applications. | Manufacturing | 🇫🇷 Lyon | 1,999 | 1955 |
| 9 | [CTC](https://www.tamtam.ai/c/ctc-lyon) (ctcgroupe.com)<br>CTC offers cross-disciplinary solutions for the leather, footwear, and textile industries, focusing on ethical practices, cost savings, waste reduction, and performance improvement worldwide | International Trade and Development | 🇫🇷 Lyon | 1,622 | 1899 |
| 10 | [NEMERA](https://www.tamtam.ai/c/nemera) (nemera.net)<br>Designs, develops, and manufactures drug delivery devices for ophthalmic, nasal, inhalation, dermal, and parenteral routes, prioritizing patient needs and treatment efficacy. | Medical Equipment Manufacturing | 🇫🇷 Lyon | 1,616 | 2015 |
| 11 | [Centre Léon Bérard](https://www.tamtam.ai/c/centre-leon-berard) (centreleonberard.fr)<br>Specialized cancer hospital and research center providing personalized treatment, innovative therapies, and compassionate care to support patients throughout their illness. | Hospitals and Health Care | 🇫🇷 Lyon | 1,418 | 1923 |
| 12 | [CNR (Compagnie Nationale du Rhône)](https://www.tamtam.ai/c/cnr-compagnie-nationale-du-rhone) (tm.fr)<br>French leading producer of 100% renewable electricity, managing the Rhône river for hydroelectricity, navigation, irrigation, and agricultural use, supporting local development and innovation | Electric Power Generation | 🇫🇷 Lyon | 1,256 | 1934 |
| 13 | [Eurofins Biomnis](https://www.tamtam.ai/c/eurofins-biomnis) (eurofins-biomnis.com)<br>A European leader in specialized medical pathology, providing over 2,500 tests including specialized, authorized analyses with a focus on innovation and international development | Medical and Diagnostic Laboratories | 🇫🇷 Lyon | 803 | 1897 |
| 14 | [Agicap](https://www.tamtam.ai/c/agicap-lyon) (agicap.com)<br>Elevating cash flow management strategies for businesses to optimize financial operations and achieve greater success | Software Development | 🇫🇷 Lyon | 685 | 2016 |
| 15 | [KEM ONE](https://www.tamtam.ai/c/kem-one) (kemone.com)<br>Industrial chemical company specializing in PVC production with activities from salt extraction to manufacturing, focusing on export markets and promoting diversity and career growth | Chemical Manufacturing | 🇫🇷 Lyon | 667 | 2012 |
| 16 | [Laboratoire Aguettant](https://www.tamtam.ai/c/laboratoire-aguettant) (aguettant-corporate.com)<br>Develops, produces, distributes innovative injectable pharmaceutical specialties for healthcare professionals and patients. European actor in hospital-initiated injectable drugs. | Pharmaceutical Manufacturing | 🇫🇷 Lyon | 611 | 1903 |
| 17 | [Babolat](https://www.tamtam.ai/c/babolat) (babolat.com)<br>Family-owned company, racquet sports equipment supplier, expertise in strings, serving tennis, padel, badminton players worldwide since 1875. | Sporting Goods Manufacturing | 🇫🇷 Lyon | 589 | 1875 |
| 18 | [Distech Controls](https://www.tamtam.ai/c/distech-controls) (distech-controls.com)<br>provides innovative building automation technologies and services enhancing health, efficiency, and sustainability across multiple global market segments | Software Development | 🇫🇷 Lyon | 507 | 1995 |
| 19 | [Novasep](https://www.tamtam.ai/c/novasep) (novasep.com)<br>Leading provider of molecule production & purification services for life science industries Specializing in small molecule APIs, natural products, purification equipment, and global R&D capabilities | Chemical Manufacturing | 🇫🇷 Lyon | 496 | 1993 |
| 20 | [Flexitech](https://www.tamtam.ai/c/flexitech) (flexitech.com)<br>Experienced engineers develop custom hose routing solutions with extensive global production ensuring quality, competitive pricing, and supplier consolidation support. | Motor Vehicle Manufacturing | 🇫🇷 Lyon | 484 | 1956 |
| 21 | [ECAM LaSalle](https://www.tamtam.ai/c/ecam-lasalle) (ecam.fr)<br>Offers five CTI-recognized engineering programs, including generalist and specialized options, a cybersecurity bachelor's, and a continuous improvement master's, located in Lyon. | Higher Education | 🇫🇷 Lyon | 364 | 1900 |
| 22 | [Indy](https://www.tamtam.ai/c/indy) (indy.fr)<br>Provides advanced AI-powered tools for businesses to manage their own bookkeeping and accounting efficiently without needing extensive financial knowledge. | Technology, Information and Internet | 🇫🇷 Lyon | 354 | 2016 |
| 23 | [Percall Group](https://www.tamtam.ai/c/percall-group) (percallgroup.com)<br>French IT engineering services company, specializing in CAD, PLM, and IoT software integration for major high-tech industries, a PTC partner. | IT Services and IT Consulting | 🇫🇷 Lyon | 347 | 2000 |
| 24 | [Gerflor France](https://www.tamtam.ai/c/gerflor-france) (gerflor.fr)<br>Designs, manufactures, and markets eco-responsible residential and professional floor coverings through global distribution, utilizing six production sites and three dedicated research and development centers. | Wholesale Building Materials | 🇫🇷 Lyon | 331 |  |
| 25 | [LA ROSÉE](https://www.tamtam.ai/c/la-rosee) (larosee-cosmetiques.com)<br>Formulates and manufactures natural, effective, eco-designed cosmetic products in France, sold in pharmacies across 12 countries. Focuses on sustainability and customer trust. | Retail Health and Personal Care Products | 🇫🇷 Lyon | 326 | 2014 |
| 26 | [ISISPHARMA](https://www.tamtam.ai/c/isispharma) (isispharma.com)<br>Development of scientifically rigorous, targeted dermatological products focused on emotional well-being and educational support for skin health balance. | Pharmaceutical Manufacturing | 🇫🇷 Lyon | 317 | 1987 |
| 27 | [FIDUCIAL Informatique](https://www.tamtam.ai/c/fiducial-informatique) (fiducial.fr)<br>design comprehensive software solutions and provide personalized services for various professional sectors including accounting, billing, payroll, and specialized industries | Software Development | 🇫🇷 Lyon | 281 | 2000 |
| 28 | [Cegid for SMB](https://www.tamtam.ai/c/cegid-for-smb) (cegid.com)<br>This company enables people to achieve more together by making more opportunities possible | Software Development | 🇫🇷 Lyon | 273 |  |
| 29 | [Ciss](https://www.tamtam.ai/c/ciss) (ciss.fr)<br>Designs, develops, and sells SaaS solutions for payment, customer relations, security, and data to enhance digital performance and trust for clients. | IT Services and IT Consulting | 🇫🇷 Lyon | 268 | 2001 |
| 30 | [LAB](https://www.tamtam.ai/c/lab-lyon) (lab.fr)<br>Engineering and construction of turnkey flue gas cleaning and condensation systems to reduce emissions and improve thermal plant efficiency. | Environmental Services | 🇫🇷 Lyon | 266 | 1953 |

## How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 11, 2026.

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## The same list elsewhere in France

- [Companies with in-house R&D in France](https://www.tamtam.ai/l/r-and-d-companies-france) (8,750)
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- [Companies with in-house R&D in the Bouches-du-Rhône department](https://www.tamtam.ai/l/r-and-d-companies-bouches-du-rhone) (321)
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- [Companies with in-house R&D in Centre-Val de Loire](https://www.tamtam.ai/l/r-and-d-companies-centre-val-de-loire) (195)
- [Companies with in-house R&D in Paris](https://www.tamtam.ai/l/r-and-d-companies-paris) (1,249)
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Source: https://www.tamtam.ai/l/r-and-d-companies-lyon