# Companies with in-house R&D headquartered in Massachusetts

Tamtam tracks 396 companies with in-house R&D headquartered in Massachusetts. This list ranks the 100 largest by number of employees on LinkedIn, led by Thermo Fisher Scientific, GE and GE Vernova. Their median headcount is 4,385. Half of them were founded in 1985 or later. The most common headquarters are Boston (33), Cambridge (12) and Waltham (7).

This selection of companies with in-house R&D in Massachusetts comprises mostly large corporations. They operate across diverse sectors, including biotechnology, medical equipment, higher education, and industrial machinery. Key players include Thermo Fisher Scientific, a global leader in science services; GE, focusing on aviation and energy industries; Boston Scientific, which develops medical technologies; and Harvard University, dedicated to teaching and research.

A notable pattern among these companies is their strong presence in Boston and Cambridge, indicating a concentration of research and development activities in these urban centers. The list also highlights a mix of well-established institutions like Harvard University, founded in 1636, and more recent technology companies such as Amazon Fulfillment Technologies & Robotics, established in 2003.

🇺🇸 Massachusetts · 100 companies · Updated Nov 11, 2026

| # | Company | Industry | Headquarters | Employees | Founded |
|---|---|---|---|---|---|
| 1 | [Thermo Fisher Scientific](https://www.tamtam.ai/c/thermo-fisher-scientific) (thermofisher.com)<br>A global leader in science services, providing innovative technologies and pharmaceutical support to make the world healthier, cleaner, and safer | Biotechnology Research | 🇺🇸 Waltham | 100,256 |  |
| 2 | [GE](https://www.tamtam.ai/c/ge) (ge.com)<br>Focus on advancing aviation and energy industries through innovative technologies and solutions shared via specialized aerospace and energy platforms. | Industrial Machinery Manufacturing | 🇺🇸 Boston | 99,488 |  |
| 3 | [GE Vernova](https://www.tamtam.ai/c/ge-vernova) (linktr.ee)<br>A purpose-built company focused on electrifying the planet and decarbonizing it through a diverse portfolio of energy businesses, ensuring reliable and sustainable energy | Energy Technology | 🇺🇸 Boston | 70,646 |  |
| 4 | [Boston Scientific](https://www.tamtam.ai/c/boston-scientific) (bostonscientific.com)<br>Develops and provides innovative medical technologies including devices and therapies for various diseases, improving patient health and reducing healthcare costs worldwide. | Medical Equipment Manufacturing | 🇺🇸 Marlborough | 54,633 |  |
| 5 | [Harvard University](https://www.tamtam.ai/c/harvard-university) (harvard.edu)<br>An institution dedicated to teaching, learning, and research, producing global leaders across disciplines since 1636 Maintains flagship social media channels | Higher Education | 🇺🇸 Cambridge | 34,940 |  |
| 6 | [Analog Devices](https://www.tamtam.ai/c/analog-devices) (analog.com)<br>Global semiconductor company combining analog, digital, and software technologies to advance digitized factories, mobility, healthcare, and climate solutions. | Semiconductor Manufacturing | 🇺🇸 Wilmington | 27,234 |  |
| 7 | [Publicis Sapient](https://www.tamtam.ai/c/publicis-sapient) (publicissapient.com)<br>A digital business transformation partner, specializing in strategy, product, experience, engineering, data, and delivering impactful solutions to global organizations | Business Consulting and Services | 🇺🇸 Boston | 24,251 |  |
| 8 | [Massachusetts Institute of Technology](https://www.tamtam.ai/c/massachusetts-institute-of-technology) (web.mit.edu)<br>A private research university in Cambridge, Massachusetts, advancing knowledge and educating students in science and technology-focused areas | Higher Education | 🇺🇸 Cambridge | 23,586 | 1861 |
| 9 | [Charles River Laboratories](https://www.tamtam.ai/c/charles-river-laboratories) (criver.com)<br>Guided by strong purpose, creating healthier lives, focusing on therapeutics for patients, animal care, planet well-being, and its passionate, skilled people. | Biotechnology Research | 🇺🇸 Wilmington | 22,000 | 1947 |
| 10 | [PPD](https://www.tamtam.ai/c/ppd) (ppd.com)<br>Global clinical development services including laboratory testing, patient recruitment, and data analytics to accelerate drug innovation for pharma, biotech, and government organizations. | Research Services | 🇺🇸 Waltham | 20,440 |  |
| 11 | [Massachusetts General Hospital](https://www.tamtam.ai/c/massachusetts-general-hospital) (massgeneral.org)<br>Dedicated to providing top-notch healthcare in a compassionate environment through innovative research and education, improving health in diverse communities served | Hospitals and Health Care | 🇺🇸 Boston | 20,001 | 1811 |
| 12 | [Amazon Fulfillment Technologies & Robotics](https://www.tamtam.ai/c/amazon-fulfillment-technologies-and-robotics) (amazon.jobs)<br>The company partners people with intelligent robots to enhance order fulfillment accuracy, create new jobs worldwide, and improve customer experience | Software Development | 🇺🇸 North Reading | 17,911 | 2003 |
| 13 | [Mass General Brigham](https://www.tamtam.ai/c/mass-general-brigham) (massgeneralbrigham.org)<br>Integrated academic health system providing patient care, research, teaching, and community services through hospitals, insurance, and specialized medical centers. | Hospitals and Health Care | 🇺🇸 Somerville | 17,890 |  |
| 14 | [Boston Children's Hospital](https://www.tamtam.ai/c/boston-children-s-hospital) (childrenshospital.org)<br>A leading pediatric medical center providing comprehensive healthcare services for children from birth to 21 years, with specialized clinical programs and renowned physicians | Hospitals and Health Care | 🇺🇸 Boston | 17,496 | 1869 |
| 15 | [Keurig Dr Pepper Inc.](https://www.tamtam.ai/c/keurig-dr-pepper-inc) (keurigdrpepper.com)<br>Leading North American beverage company with extensive portfolio including coffee, soft drinks, water, juice, and mixers, strong distribution network. | Food and Beverage Services | 🇺🇸 Burlington | 13,948 |  |
| 16 | [Wayfair](https://www.tamtam.ai/c/wayfair) (aboutwayfair.com)<br>Destination for all things home, offering expert customer service, tools for easy shopping, and wide selection to help create personalized spaces | Retail | 🇺🇸 Boston | 12,524 | 2002 |
| 17 | [Harvard Business School](https://www.tamtam.ai/c/harvard-business-school) (hbs.edu)<br>Offers MBA, PhD, executive education, and online programs focused on leadership development, business practice, and entrepreneurship worldwide. | Higher Education | 🇺🇸 Boston | 12,457 | 1908 |
| 18 | [HubSpot](https://www.tamtam.ai/c/hubspot) (hubspot.com)<br>It provides a comprehensive CRM platform with marketing, sales, and service tools, fostering employee growth and a flexible workplace culture. | Software Development | 🇺🇸 Cambridge | 12,229 | 2006 |
| 19 | [Harvard Medical School](https://www.tamtam.ai/c/harvard-medical-school) (hms.harvard.edu)<br>A prestigious medical school fostering a diverse community of leaders dedicated to advancing knowledge, education, and research to alleviate human suffering | Higher Education | 🇺🇸 Boston | 12,076 |  |
| 20 | [University at Buffalo](https://www.tamtam.ai/c/university-at-buffalo) (buffalo.edu)<br>Extraordinary community, creative activity and research changing the world. New York State's flagship university, AAU member. | Higher Education | 🇺🇸 Burlington | 11,906 | 1846 |
| 21 | [Waters Corporation](https://www.tamtam.ai/c/waters-corporation) (waters.com)<br>A global leader in analytical instruments and software, pioneering innovations in chromatography, mass spectrometry, and thermal analysis for various sciences | Biotechnology Research | 🇺🇸 Milford | 11,842 |  |
| 22 | [New Balance](https://www.tamtam.ai/c/new-balance) (newbalance.com)<br>Designing and manufacturing high-quality athletic footwear and apparel with a focus on comfort, fit, innovation, and community support worldwide. | Sporting Goods Manufacturing | 🇺🇸 Brighton | 11,624 | 1906 |
| 23 | [University of Massachusetts Amherst](https://www.tamtam.ai/c/university-of-massachusetts-amherst) (umass.edu)<br>A top-ranked teaching and research institution in western Massachusetts with about 28,500 students, part of the University of Massachusetts system | Higher Education | 🇺🇸 Amherst | 11,525 | 1863 |
| 24 | [UMass Memorial Health](https://www.tamtam.ai/c/umass-memorial-health) (ummhealth.org)<br>Largest healthcare system in Central Massachusetts offering hospital care, outpatient services, medical training, research, and community health support. | Hospitals and Health Care | 🇺🇸 Worcester | 10,819 | 1999 |
| 25 | [Akamai Technologies](https://www.tamtam.ai/c/akamai-technologies) (akamai.com)<br>A global leader in internet infrastructure, Akamai powers and protects online experiences for billions of users daily through innovative solutions | Technology, Information and Internet | 🇺🇸 Cambridge | 10,647 |  |
| 26 | [Dana-Farber Cancer Institute](https://www.tamtam.ai/c/dana-farber-cancer-institute) (dana-farber.org)<br>Providing expert, compassionate care to children and adults with cancer while advancing understanding, treatment, cure, and prevention. | Hospitals and Health Care | 🇺🇸 Boston | 8,981 | 1947 |
| 27 | [athenahealth](https://www.tamtam.ai/c/athenahealth) (athenahealth.com)<br>The company strives to simplify healthcare with innovative technology for electronic health records, revenue cycle management, and patient engagement solutions | IT Services and IT Consulting | 🇺🇸 Boston | 8,956 | 1997 |
| 28 | [Netcracker Technology](https://www.tamtam.ai/c/netcracker-technology) (netcracker.com)<br>It is a software company providing critical solutions for service providers, focusing on digital transformation and cloud opportunities worldwide. | Telecommunications | 🇺🇸 Waltham | 8,935 | 1993 |
| 29 | [PTC](https://www.tamtam.ai/c/ptc) (ptc.com)<br>It provides solutions for manufacturers to enhance product differentiation, operational excellence, and workforce productivity through digital transformation and technology. | Software Development | 🇺🇸 Boston | 8,184 |  |
| 30 | [Toast](https://www.tamtam.ai/c/toast-boston) (pos.toasttab.com)<br>Toast empowers restaurants with cloud-based software and hardware to streamline operations, drive revenue, and enhance guest experience through POS, marketing, and HR solutions | Software Development | 🇺🇸 Boston | 7,762 | 2011 |
| 31 | [Biogen](https://www.tamtam.ai/c/biogen) (biogen.com)<br>Company pioneers innovative science, delivering new medicines to transform patients' lives, with a global presence and focus on superior treatment outcomes. | Biotechnology Research | 🇺🇸 Cambridge | 7,724 |  |
| 32 | [Sensata Technologies](https://www.tamtam.ai/c/sensata-technologies) (sensata.com)<br>Supplier of sensing, electrical protection, control, and power management solutions enhancing safety, efficiency, and comfort across multiple industries worldwide. | Appliances, Electrical, and Electronics Manufacturing | 🇺🇸 Attleboro | 7,634 |  |
| 33 | [Hologic, Inc.](https://www.tamtam.ai/c/hologic-inc) (hologic.com)<br>Develops innovative medical products, especially for women's health, focusing on early detection and better outcomes across breast, skeletal, diagnostic, and GYN surgical solutions. | Medical Equipment Manufacturing | 🇺🇸 Marlborough | 6,921 | 1985 |
| 34 | [Moderna](https://www.tamtam.ai/c/moderna) (modernatx.com)<br>Pioneering mRNA technology for new medicines to improve patient lives by providing real-time instructions for protein production in cells | Biotechnology Research | 🇺🇸 Cambridge | 6,906 | 2010 |
| 35 | [Partners HealthCare](https://www.tamtam.ai/c/partners-healthcare) (partners.org)<br>Integrated healthcare system offering coordinated care, high-quality services, research, teaching, and community outreach through academic medical centers and various healthcare entities | Hospitals and Health Care | 🇺🇸 Somerville | 6,751 | 1994 |
| 36 | [Bose Corporation](https://www.tamtam.ai/c/bose-corporation) (bose.com)<br>Develops advanced audio technologies and products for home, automotive, portable, and public spaces, enhancing music listening experiences worldwide. | Computers and Electronics Manufacturing | 🇺🇸 Framingham | 6,699 |  |
| 37 | [Entegris](https://www.tamtam.ai/c/entegris) (entegris.com)<br>A global leader in advanced science-based solutions for technology challenges, driving innovation with artificial intelligence, augmented reality, and IoT technologies | Semiconductor Manufacturing | 🇺🇸 Billerica | 6,612 |  |
| 38 | [Vertex Pharmaceuticals](https://www.tamtam.ai/c/vertex-pharmaceuticals) (vrtx.com)<br>Global biotechnology company focusing on creating medicines for serious and life-threatening diseases, with a pioneering history in treating cystic fibrosis | Biotechnology Research | 🇺🇸 Boston | 6,382 | 1989 |
| 39 | [Baystate Health](https://www.tamtam.ai/c/baystate-health) (baystatehealth.org)<br>Largest healthcare organization in western Massachusetts providing quality, compassionate care across hospitals, improving community health and economic impact. | Hospitals and Health Care | 🇺🇸 Springfield | 6,269 | 1873 |
| 40 | [Teradyne](https://www.tamtam.ai/c/teradyne) (teradyne.com)<br>This company provides advanced test solutions for semiconductors, electronic systems, wireless devices, and robotics to improve productivity and lower costs for manufacturers worldwide | Semiconductor Manufacturing | 🇺🇸 North Reading | 6,210 | 1960 |
| 41 | [Dynatrace](https://www.tamtam.ai/c/dynatrace) (dynatrace.com)<br>This company specializes in providing a platform that unifies observability, business, and security data with AI-driven analytics and automation to optimize cloud operations and ensure flawless digital experiences | Software Development | 🇺🇸 Boston | 6,090 |  |
| 42 | [Veolia \| North America](https://www.tamtam.ai/c/veolia-north-america) (veolianorthamerica.com)<br>Provides resource management solutions including water decontamination, toxic waste handling, fossil fuel alternatives, wastewater reuse, and battery recycling for cities and industries. | Environmental Services | 🇺🇸 Boston | 5,812 |  |
| 43 | [DraftKings Inc.](https://www.tamtam.ai/c/draftkings-inc) (careers.draftkings.com)<br>The company is committed to creating popular games and betting experiences, leading the way in sports entertainment, innovation, and global collaboration | Mobile Gaming Apps | 🇺🇸 Boston | 5,760 | 2012 |
| 44 | [Pegasystems](https://www.tamtam.ai/c/pegasystems) (pega.com)<br>It provides a low-code platform for organizations to enhance agility, automate workflows, and address business challenges using AI technology. | Software Development | 🇺🇸 Waltham | 5,569 |  |
| 45 | [eClinicalWorks](https://www.tamtam.ai/c/eclinicalworks) (eclinicalworks.com)<br>It provides Electronic Health Record and Practice Management solutions to medical professionals, enhancing care quality and reducing costs through technology. | Software Development | 🇺🇸 Westborough | 5,426 | 1999 |
| 46 | [Insulet Corporation](https://www.tamtam.ai/c/insulet-corporation) (insulet.com)<br>Simplifying diabetes management for individuals with the Omnipod platform, offering tubeless, wearable insulin delivery and automated blood sugar control without injections or fingersticks globally. | Medical Equipment Manufacturing | 🇺🇸 Acton | 5,407 | 2000 |
| 47 | [Alexion Pharmaceuticals, Inc.](https://www.tamtam.ai/c/alexion-pharmaceuticals-inc) (alexion.com)<br>Development of innovative medicines targeting rare diseases, focusing on complement system biology, expanding global reach to serve patients worldwide. | Biotechnology Research | 🇺🇸 Boston | 5,112 | 1992 |
| 48 | [Bruker](https://www.tamtam.ai/c/bruker) (bruker.com)<br>Development and provision of advanced analytical instrumentation and solutions for research, industrial production, quality assurance, and process reliability worldwide. | Biotechnology Research | 🇺🇸 Billerica | 4,824 | 1960 |
| 49 | [MKS Inc.](https://www.tamtam.ai/c/mks-inc) (mks.com)<br>provides technology solutions including instruments, systems, and specialty chemicals for semiconductor manufacturing, electronics, packaging, and specialty industrial applications | Semiconductor Manufacturing | 🇺🇸 Andover | 4,581 | 1961 |
| 50 | [Rocket Software](https://www.tamtam.ai/c/rocket-software) (rocketsoftware.com)<br>Partner for organizations transforming IT infrastructure, applications, and data from core systems to cloud with global support and innovation. | IT Services and IT Consulting | 🇺🇸 Waltham | 4,385 |  |
| 51 | [Progress Software](https://www.tamtam.ai/c/progress-software) (progress.com)<br>Helping businesses drive innovation and success with high-impact application products, deployment flexibility, and secure management solutions, trusted by enterprises and developers worldwide | Software Development | 🇺🇸 Burlington | 4,212 | 1981 |
| 52 | [SharkNinja](https://www.tamtam.ai/c/sharkninja) (sharkninja.com)<br>A global product design and technology company known for innovative 5-star rated lifestyle solutions in household product categories like Cleaning, Cooking, and Food Preparation | Appliances, Electrical, and Electronics Manufacturing | 🇺🇸 Needham | 4,199 | 1994 |
| 53 | [Quantiphi](https://www.tamtam.ai/c/quantiphi) (quantiphi.com)<br>An AI-first digital engineering company that solves complex business problems with industry experience, cloud, data engineering, and cutting-edge AI research | IT Services and IT Consulting | 🇺🇸 Marlborough | 4,105 | 2013 |
| 54 | [Aspen Technology](https://www.tamtam.ai/c/aspen-technology) (aspentech.com)<br>Global software leader enabling industries to meet demand sustainably by optimizing asset design, operation, and maintenance lifecycle for improved operational excellence | Software Development | 🇺🇸 Bedford | 4,065 |  |
| 55 | [Roswell Park Comprehensive Cancer Center](https://www.tamtam.ai/c/roswell-park-comprehensive-cancer-center) (roswellpark.org)<br>A comprehensive cancer center offering cutting-edge care, research, and education to reduce the cancer burden and set national standards | Hospitals and Health Care | 🇺🇸 Burlington | 3,751 | 1898 |
| 56 | [Cabot Corporation](https://www.tamtam.ai/c/cabot-corporation) (cabotcorp.com)<br>Global specialty chemical and performance materials company providing solutions to address current challenges and future customer needs worldwide. | Chemical Manufacturing | 🇺🇸 Boston | 3,719 | 1882 |
| 57 | [MEDITECH](https://www.tamtam.ai/c/meditech) (ehr.meditech.com)<br>Healthcare organization empowering digital transformation with an intuitive and interoperable EHR system, cloud-based solutions, and personalized mobile tools to enhance efficiency and outcomes | IT Services and IT Consulting | 🇺🇸 Canton | 3,702 | 1969 |
| 58 | [Revvity](https://www.tamtam.ai/c/revvity) (revvity.com)<br>Revvity specializes in innovative health science solutions, technologies, and services for healthcare advancements worldwide, covering discovery, development, and diagnosis to cure | Biotechnology Research | 🇺🇸 Waltham | 3,569 | 2023 |
| 59 | [University of Massachusetts](https://www.tamtam.ai/c/university-of-massachusetts) (youtube.com)<br>Public university system offering high-quality education, conducting extensive research, and providing impactful public service to communities locally and globally. | Higher Education | 🇺🇸 Boston | 3,476 | 1863 |
| 60 | [BeOne Medicines](https://www.tamtam.ai/c/beone-medicines) (beonemedicines.com)<br>Developing innovative, affordable cancer treatments for hematology and solid tumors with a global team and collaborative approach. | Pharmaceutical Manufacturing | 🇺🇸 Cambridge | 3,350 | 2010 |
| 61 | [Rapid7](https://www.tamtam.ai/c/rapid7) (rapid7.com)<br>Global leader in AI-powered managed cybersecurity operations, advancing organizations' cyber resilience through integrating security data, AI, and threat intelligence to reduce risk and disrupt attackers. | Computer and Network Security | 🇺🇸 Boston | 3,268 |  |
| 62 | [Broad Institute of MIT and Harvard](https://www.tamtam.ai/c/broad-institute-of-mit-and-harvard) (broadinstitute.org)<br>Multidisciplinary teams collaborate across labs and programs to address complex biomedical challenges in human biology and disease worldwide. | Research Services | 🇺🇸 Cambridge | 3,204 | 2003 |
| 63 | [Saint-Gobain Abrasives](https://www.tamtam.ai/c/saint-gobain-abrasives) (saint-gobain-surfacesolutions.com)<br>The company offers powerful and precise abrasives solutions for various markets, focusing on customization, performance, and safety with global presence | Industrial Machinery Manufacturing | 🇺🇸 Worcester | 3,196 | 1885 |
| 64 | [Precisely](https://www.tamtam.ai/c/precisely) (precisely.com)<br>Provides data integrity solutions that enhance data quality, integrate datasets, and support analytics for organizations worldwide, ensuring reliable business insights. | Software Development | 🇺🇸 Burlington | 3,014 |  |
| 65 | [CCL Label](https://www.tamtam.ai/c/ccl-label) (ccllabel.com)<br>Global leader in innovative label solutions for various industries, offering pressure sensitive and extruded film materials, metal components, and complementary products worldwide | Packaging and Containers Manufacturing | 🇺🇸 Framingham | 2,988 | 1951 |
| 66 | [Draper](https://www.tamtam.ai/c/draper) (draper.com)<br>A nonprofit engineering innovation company advancing technologies for national security through collaboration with government, academia, and industry to solve complex challenges | Defense and Space Manufacturing | 🇺🇸 Cambridge | 2,932 |  |
| 67 | [Suffolk Construction](https://www.tamtam.ai/c/suffolk-construction) (suffolk.com)<br>National construction management firm providing real estate investment, design, self-perform construction, technology investment, and innovation research services across multiple industries. | Construction | 🇺🇸 Boston | 2,923 | 1982 |
| 68 | [Viant Medical](https://www.tamtam.ai/c/viant-medical) (viantmedical.com)<br>Global provider of design and manufacturing services for medical devices across various specialties, offering end-to-end capabilities from development to packaging. | Medical Equipment Manufacturing | 🇺🇸 Foxborough | 2,921 |  |
| 69 | [Klaviyo](https://www.tamtam.ai/c/klaviyo) (klaviyo.com)<br>Unified customer platform empowering brands with ownership of consumer data to automate personalized email/SMS communications, foster customer relationships, and drive growth | Marketing Services | 🇺🇸 Boston | 2,902 | 2012 |
| 70 | [Alnylam Pharmaceuticals](https://www.tamtam.ai/c/alnylam-pharmaceuticals) (alnylam.com)<br>A global biotech company pioneering RNAi therapeutics to treat rare genetic diseases, with a breakthrough product and a robust pipeline | Biotechnology Research | 🇺🇸 Cambridge | 2,883 | 2002 |
| 71 | [CyberArk](https://www.tamtam.ai/c/cyberark) (cyberark.com)<br>Global leader in identity security. Offers comprehensive security for human and machine identities across applications, workforces, cloud, and DevOps lifecycle. | IT System Custom Software Development | 🇺🇸 Newton | 2,712 | 1999 |
| 72 | [NETSCOUT](https://www.tamtam.ai/c/netscout) (netscout.com)<br>This company provides a Visibility Without Borders platform to help essential organizations manage complex networks, unlock insights, anticipate problems, and stay unstoppable | Software Development | 🇺🇸 Westford | 2,708 | 1984 |
| 73 | [Acushnet Company](https://www.tamtam.ai/c/acushnet-company) (employment.acushnetgolf.com)<br>Leading golf company offering high-quality golf equipment, apparel, and accessories for serious and recreational golfers worldwide. | Manufacturing | 🇺🇸 Fairhaven | 2,611 |  |
| 74 | [Cognex Corporation](https://www.tamtam.ai/c/cognex-corporation) (cognex.com)<br>Advanced machine vision technology enabling manufacturing and distribution companies to improve quality, efficiency, and automation with AI-powered vision sensors and systems. | Automation Machinery Manufacturing | 🇺🇸 Natick | 2,580 | 1981 |
| 75 | [EMC](https://www.tamtam.ai/c/emc) (dell.com)<br>Logo update for a company former owner was EMC, now owned by Dell The company's original logo is being reinstated | IT Services and IT Consulting | 🇺🇸 Hopkinton | 2,532 |  |
| 76 | [Spaulding Rehabilitation Hospital](https://www.tamtam.ai/c/spaulding-rehabilitation-hospital) (spauldingrehab.org)<br>A leading rehabilitation facility providing comprehensive treatment, part of a network with specialty hospitals, skilled nursing facilities, and outpatient centers in Eastern Massachusetts | Hospitals and Health Care | 🇺🇸 Boston | 2,441 | 1971 |
| 77 | [Abiomed](https://www.tamtam.ai/c/abiomed) (abiomed.com)<br>A leading provider of medical technology based in Danvers, MA, offering products for circulatory support and oxygenation to help patients recover | Medical Equipment Manufacturing | 🇺🇸 Danvers | 2,388 | 1981 |
| 78 | [Semrush](https://www.tamtam.ai/c/semrush) (semrush.com)<br>A leading online visibility management platform offering a suite of marketing tools to help companies improve their online presence and results | Software Development | 🇺🇸 Boston | 2,357 | 2008 |
| 79 | [argenx](https://www.tamtam.ai/c/argenx) (argenx.com)<br>Global immunology company focused on developing novel antibody-based medicines for severe autoimmune diseases through collaborations with leading researchers | Biotechnology Research | 🇺🇸 Boston | 2,315 | 2008 |
| 80 | [Mercury Systems](https://www.tamtam.ai/c/mercury-systems) (mrcy.com)<br>A technology company pushing processing power to the tactical edge for aerospace and defense missions, enabling innovation and decision superiority worldwide | Defense and Space Manufacturing | 🇺🇸 Andover | 2,300 | 1981 |
| 81 | [McLean Hospital](https://www.tamtam.ai/c/mclean-hospital) (mcleanhospital.org)<br>A leading psychiatric hospital dedicated to treating mental health conditions, conducting innovative research, and providing education to improve patient outcomes | Mental Health Care | 🇺🇸 Belmont | 2,296 | 1811 |
| 82 | [Curium Pharma](https://www.tamtam.ai/c/curium-pharma) (curiumpharma.com)<br>Global leader in nuclear medicine, providing life-changing diagnostics and treatment for cancer patients worldwide through innovative radiopharmaceutical products and AI-driven solutions | Pharmaceutical Manufacturing | 🇺🇸 Boston | 2,236 | 2017 |
| 83 | [OutSystems](https://www.tamtam.ai/c/outsystems) (outsystems.com)<br>Provides an AI development platform for enterprises to rapidly build custom applications and AI agents while modernizing legacy core business systems. | Software Development | 🇺🇸 Boston | 2,228 | 2001 |
| 84 | [Perk](https://www.tamtam.ai/c/perk) (perk.com)<br>A hyper-growth SaaS business travel platform revolutionizing business travel with an all-in-one solution for companies and organizations worldwide | Technology, Information and Internet | 🇺🇸 Boston | 2,228 | 2015 |
| 85 | [Novanta Inc.](https://www.tamtam.ai/c/novanta-inc) (novanta.com)<br>Supplier of advanced technology solutions in precision medicine, manufacturing, robotics, and surgery, enabling high-performance, tailored equipment for OEMs. | Manufacturing | 🇺🇸 Bedford | 2,189 |  |
| 86 | [MACOM](https://www.tamtam.ai/c/macom) (macom.com)<br>A semiconductor company with expertise in Data Center, Telecommunication, and Industrial/Defense applications, offering design, manufacturing, and distribution services globally | Semiconductor Manufacturing | 🇺🇸 Lowell | 2,182 | 1950 |
| 87 | [InterSystems](https://www.tamtam.ai/c/intersystems) (intersystems.com)<br>InterSystems provides data platforms and connected care solutions for healthcare, business, and government to drive better decisions and outcomes worldwide | Software Development | 🇺🇸 Boston | 2,127 | 1978 |
| 88 | [Symbotic](https://www.tamtam.ai/c/symbotic) (symbotic.com)<br>This company develops innovative robotics and software for advanced automation solutions in the supply chain industry to increase efficiency and profitability | Automation Machinery Manufacturing | 🇺🇸 Wilmington | 2,074 | 2007 |
| 89 | [BCG X](https://www.tamtam.ai/c/bcg-x) (bcg.com)<br>Builds and designs platforms and software with advanced tech knowledge and entrepreneurship to enable innovation and address challenges for organizations. | Technology, Information and Internet | 🇺🇸 Boston | 2,033 |  |
| 90 | [ArisGlobal](https://www.tamtam.ai/c/arisglobal) (arisglobal.com)<br>Transforms life sciences companies by automating drug development with an integrated technology platform, boosting efficiency, ensuring compliance, and reducing costs. | Software Development | 🇺🇸 Waltham | 2,028 | 1987 |
| 91 | [HP Hood LLC](https://www.tamtam.ai/c/hp-hood-llc) (hood.com)<br>Established in 1846, this company is a leading dairy processor in the US, known for high-quality dairy products under various brands | Food and Beverage Manufacturing | 🇺🇸 Lynnfield | 2,006 | 1846 |
| 92 | [Brooks Automation](https://www.tamtam.ai/c/brooks-automation) (brooks.com)<br>Provider of automation solutions for the semiconductor industry, specializing in robotics, automation systems, and contamination control to empower chip manufacturers worldwide | Semiconductor Manufacturing | 🇺🇸 Chelmsford | 1,982 | 1978 |
| 93 | [BeiGene](https://www.tamtam.ai/c/beigene) (beonemedicines.com)<br>Global oncology company developing accessible and affordable cancer treatments through innovative research, collaborations, and commitment to improving medicine access for patients worldwide | Biotechnology Research | 🇺🇸 Cambridge | 1,967 | 2010 |
| 94 | [Harvard Medical School and Massachusetts General Hospital](https://www.tamtam.ai/c/harvard-medical-school-and-massachusetts-general-hospital) (massgeneral.org)<br>A prestigious hospital affiliated with Harvard Medical School, offering clinical experience and clerkships while supporting a large research enterprise | Higher Education | 🇺🇸 Boston | 1,967 | 1811 |
| 95 | [Werfen North America](https://www.tamtam.ai/c/werfen-north-america) (werfen.com)<br>Worldwide leader specialized diagnostics: hemostasis, acute care, transfusion, autoimmunity, transplant. Operates in over 100 territories, with headquarters in Barcelona, Spain, and technology centers in the US and Europe. | Medical Equipment Manufacturing | 🇺🇸 Bedford | 1,933 | 1959 |
| 96 | [Duck Creek Technologies](https://www.tamtam.ai/c/duck-creek-technologies) (duckcreek.com)<br>Provides cloud-based software solutions for property, casualty, and general insurance industries enabling agile, intelligent, and transparent insurance operations. | Software Development | 🇺🇸 Boston | 1,904 | 2000 |
| 97 | [IPG Photonics](https://www.tamtam.ai/c/ipg-photonics) (ipgphotonics.com)<br>Global leader in fiber laser technology, providing reliable and efficient laser solutions across various industries with a strong focus on innovation and customer needs | Appliances, Electrical, and Electronics Manufacturing | 🇺🇸 Oxford | 1,901 |  |
| 98 | [Creation Technologies](https://www.tamtam.ai/c/creation-technologies) (creationtech.com)<br>Global Electronics Manufacturing Services provider with 14 locations worldwide offering Full Product Development, Manufacturing, Test & Design Services for OEMs in various industries | Manufacturing | 🇺🇸 Boston | 1,882 | 1991 |
| 99 | [Sovos](https://www.tamtam.ai/c/sovos) (sovos.com)<br>Sovos provides scalable, secure, and user-friendly IT solutions for businesses to navigate global compliance regulations, serving Fortune 500 companies and organizations worldwide | Software Development | 🇺🇸 Wilmington | 1,861 | 2015 |
| 100 | [Mass General Hospital](https://www.tamtam.ai/c/mass-general-hospital) (massgeneral.org)<br>A higher education company located in Cambridge, Massachusetts, United States, specializing in providing healthcare services and medical research at Mass General Hospital | Higher Education | 🇺🇸 Cambridge | 1,839 |  |

## How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 11, 2026.

## More company lists in Massachusetts

- [The largest companies in Massachusetts](https://www.tamtam.ai/l/largest-companies-massachusetts) (3,419)
- [Multinational companies in Massachusetts](https://www.tamtam.ai/l/multinational-companies-massachusetts) (637)
- [SaaS companies in Massachusetts](https://www.tamtam.ai/l/saas-companies-massachusetts) (339)
- [Education providers in Massachusetts](https://www.tamtam.ai/l/education-companies-massachusetts) (313)
- [Software Development companies in Massachusetts](https://www.tamtam.ai/l/software-development-companies-massachusetts) (273)
- [Manufacturers in Massachusetts](https://www.tamtam.ai/l/manufacturers-massachusetts) (269)
- [Professional services firms in Massachusetts](https://www.tamtam.ai/l/professional-services-firms-massachusetts) (249)
- [AI companies in Massachusetts](https://www.tamtam.ai/l/ai-companies-massachusetts) (243)
- [Financial services firms in Massachusetts](https://www.tamtam.ai/l/financial-services-firms-massachusetts) (235)
- [Healthcare providers in Massachusetts](https://www.tamtam.ai/l/healthcare-providers-massachusetts) (213)
- [Hospitals and Health Care companies in Massachusetts](https://www.tamtam.ai/l/hospitals-and-health-care-companies-massachusetts) (197)
- [Hardware manufacturers in Massachusetts](https://www.tamtam.ai/l/hardware-companies-massachusetts) (196)
- [Subscription businesses in Massachusetts](https://www.tamtam.ai/l/subscription-businesses-massachusetts) (183)
- [IT Services and IT Consulting companies in Massachusetts](https://www.tamtam.ai/l/it-services-and-it-consulting-companies-massachusetts) (176)
- [Retail chains in Massachusetts](https://www.tamtam.ai/l/retail-chains-massachusetts) (168)
- [Critical infrastructure operators in Massachusetts](https://www.tamtam.ai/l/critical-infrastructure-operators-massachusetts) (165)
- [Companies with a mobile app in Massachusetts](https://www.tamtam.ai/l/companies-with-mobile-app-massachusetts) (159)
- [Higher Education companies in Massachusetts](https://www.tamtam.ai/l/higher-education-companies-massachusetts) (158)
- [Venture capital and private equity firms in Massachusetts](https://www.tamtam.ai/l/vc-and-private-equity-firms-massachusetts) (157)
- [IT services companies in Massachusetts](https://www.tamtam.ai/l/it-services-companies-massachusetts) (155)
- [Consulting firms in Massachusetts](https://www.tamtam.ai/l/consulting-firms-massachusetts) (153)
- [Financial Services companies in Massachusetts](https://www.tamtam.ai/l/financial-services-companies-massachusetts) (153)
- [Pharmaceutical companies in Massachusetts](https://www.tamtam.ai/l/pharmaceutical-companies-massachusetts) (143)
- [Publicly traded companies in Massachusetts](https://www.tamtam.ai/l/publicly-traded-companies-massachusetts) (125)

## The same list elsewhere in United States

- [Companies with in-house R&D in the United States](https://www.tamtam.ai/l/r-and-d-companies-united-states) (6,796)
- [Companies with in-house R&D in California](https://www.tamtam.ai/l/r-and-d-companies-california) (1,276)
- [Companies with in-house R&D in Texas](https://www.tamtam.ai/l/r-and-d-companies-texas) (442)
- [Companies with in-house R&D in New York State](https://www.tamtam.ai/l/r-and-d-companies-new-york-state) (419)
- [Companies with in-house R&D in Illinois](https://www.tamtam.ai/l/r-and-d-companies-illinois) (322)
- [Companies with in-house R&D in Michigan](https://www.tamtam.ai/l/r-and-d-companies-michigan) (287)
- [Companies with in-house R&D in Ohio](https://www.tamtam.ai/l/r-and-d-companies-ohio) (277)
- [Companies with in-house R&D in Pennsylvania](https://www.tamtam.ai/l/r-and-d-companies-pennsylvania) (255)
- [Companies with in-house R&D in New Jersey](https://www.tamtam.ai/l/r-and-d-companies-new-jersey) (224)
- [Companies with in-house R&D in Florida](https://www.tamtam.ai/l/r-and-d-companies-florida) (221)
- [Companies with in-house R&D in Alabama](https://www.tamtam.ai/l/r-and-d-companies-alabama) (214)
- [Companies with in-house R&D in Georgia](https://www.tamtam.ai/l/r-and-d-companies-georgia) (173)
- [Companies with in-house R&D in Virginia](https://www.tamtam.ai/l/r-and-d-companies-virginia) (166)
- [Companies with in-house R&D in North Carolina](https://www.tamtam.ai/l/r-and-d-companies-north-carolina) (158)
- [Companies with in-house R&D in Wisconsin](https://www.tamtam.ai/l/r-and-d-companies-wisconsin) (154)
- [Companies with in-house R&D in Minnesota](https://www.tamtam.ai/l/r-and-d-companies-minnesota) (146)
- [Companies with in-house R&D in Washington State](https://www.tamtam.ai/l/r-and-d-companies-washington-state) (140)
- [Companies with in-house R&D in Colorado](https://www.tamtam.ai/l/r-and-d-companies-colorado) (113)
- [Companies with in-house R&D in Maryland](https://www.tamtam.ai/l/r-and-d-companies-maryland) (107)
- [Companies with in-house R&D in Indiana](https://www.tamtam.ai/l/r-and-d-companies-indiana) (104)
- [Companies with in-house R&D in New York](https://www.tamtam.ai/l/r-and-d-companies-new-york) (223)
- [Companies with in-house R&D in San Francisco](https://www.tamtam.ai/l/r-and-d-companies-san-francisco) (147)
- [Companies with in-house R&D in Houston](https://www.tamtam.ai/l/r-and-d-companies-houston) (129)
- [Companies with in-house R&D in San Jose](https://www.tamtam.ai/l/r-and-d-companies-san-jose) (103)

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Source: https://www.tamtam.ai/l/r-and-d-companies-massachusetts