# List of companies with in-house R&D in Milan

Tamtam tracks 124 companies with in-house R&D headquartered in Milan. This list ranks the 30 largest by number of employees on LinkedIn, led by Saipem, Prysmian and Luxottica. Their median headcount is 3,897. Half of them were founded in 1957 or later.

The companies listed here are large, established firms with significant employee numbers, predominantly headquartered in Milano. They represent a mix of industries, including manufacturing, luxury goods, engineering, and healthcare. Many of these companies have a global presence and a long history.

Notable examples include Saipem, a global leader in engineering and construction for energy and infrastructure projects, and Prysmian, specializing in high-tech cables and systems. Luxottica designs and distributes fashion eyewear globally, while Pirelli is a leading tyre producer. Mapei manufactures chemical products for the building industry, and Gruppo San Donato is a large European healthcare group. The data shows a strong presence of companies founded in the late 19th and early 20th centuries, indicating a long-standing industrial tradition in Milano.

🇮🇹 Milan · 30 companies · Updated Nov 11, 2026

| # | Company | Industry | Headquarters | Employees | Founded |
|---|---|---|---|---|---|
| 1 | [Saipem](https://www.tamtam.ai/c/saipem) (saipem.com)<br>Global leader in engineering and construction for energy and infrastructure projects worldwide, offering offshore and onshore services with a focus on sustainability and innovation | Engineering Services | 🇮🇹 Milan | 32,000 | 1957 |
| 2 | [Prysmian](https://www.tamtam.ai/c/prysmian) (prysmian.com)<br>A global leader in high-tech cables & systems for energy and telecom, driving the energy transition and digitalization worldwide | Manufacturing | 🇮🇹 Milan | 28,000 | 1872 |
| 3 | [Luxottica](https://www.tamtam.ai/c/luxottica) (essilorluxottica.com)<br>Luxottica designs, manufactures, and distributes fashion eyewear globally, with a focus on sustainability, universal beauty, and well-being | Retail Luxury Goods and Jewelry | 🇮🇹 Milan | 18,182 |  |
| 4 | [Pirelli](https://www.tamtam.ai/c/pirelli) (pirelli.com)<br>A global leader in tyre production with a strong focus on technological innovation, high-end quality, and Italian heritage, catering to consumer markets worldwide | Motor Vehicle Manufacturing | 🇮🇹 Milan | 15,159 | 1872 |
| 5 | [Prada Group](https://www.tamtam.ai/c/prada-group) (pradagroup.com)<br>A luxury fashion group with diverse brands focusing on creative independence, sustainability, and global distribution of ready-to-wear, leather goods, and footwear | Retail Luxury Goods and Jewelry | 🇮🇹 Milan | 12,267 |  |
| 6 | [Politecnico di Milano](https://www.tamtam.ai/c/politecnico-di-milano) (polimi.it)<br>A scientific-technological university focusing on high-quality teaching, research, and collaboration with businesses worldwide to drive innovation and internationalization | Research Services | 🇮🇹 Milan | 10,413 |  |
| 7 | [Gruppo San Donato](https://www.tamtam.ai/c/gruppo-san-donato) (grupposandonato.it)<br>Large European healthcare group integrating hospitals, research, universities, clinics, focusing on human-centered care and international expansion. | Hospitals and Health Care | 🇮🇹 Milan | 9,474 | 1957 |
| 8 | [Mapei](https://www.tamtam.ai/c/mapei) (mapei.com)<br>A leading manufacturer of chemical products for the building industry, contributing to global architectural and infrastructural projects with a focus on specialization, internationalization, R&D, and sustainability | Chemical Manufacturing | 🇮🇹 Milan | 7,645 | 1937 |
| 9 | [Accenture Italia](https://www.tamtam.ai/c/accenture-italia) (accenture.com)<br>Global professional services firm specializing in digital, cloud, security, strategy, consulting, technology, and operations across multiple industries worldwide. | IT Services and IT Consulting | 🇮🇹 Milan | 7,209 |  |
| 10 | [DOLCE&GABBANA](https://www.tamtam.ai/c/dolce-and-gabbana) (dolcegabbana.com)<br>Luxury fashion brand specializing in clothing, accessories, jewelry, and watches inspired by Italian art, tradition, and craftsmanship. | Retail Luxury Goods and Jewelry | 🇮🇹 Milan | 6,846 | 1985 |
| 11 | [Dedalus](https://www.tamtam.ai/c/dedalus) (dedalus.com)<br>This company is a leading healthcare and diagnostic software provider in Europe, facilitating digital transformation for healthcare systems worldwide | IT Services and IT Consulting | 🇮🇹 Milan | 6,177 | 1982 |
| 12 | [Ospedale San Raffaele](https://www.tamtam.ai/c/ospedale-san-raffaele) (hsr.it)<br>A high-specialization center within Gruppo San Donato focusing on medical, scientific research, and university education to deliver excellence in healthcare | Hospitals and Health Care | 🇮🇹 Milan | 4,965 | 1971 |
| 13 | [Recordati](https://www.tamtam.ai/c/recordati) (recordati.com)<br>Global pharmaceutical company developing and commercializing medicines for common and rare diseases, dedicated to improving health and unlocking the full potential of life | Pharmaceutical Manufacturing | 🇮🇹 Milan | 4,331 | 1926 |
| 14 | [Edison](https://www.tamtam.ai/c/edison-milano) (edison.it)<br>Leading energy company with 140 years history, operating in renewable production, gas supply, sustainable mobility, and energy services across Europe. | Utilities | 🇮🇹 Milan | 4,174 | 1884 |
| 15 | [MAIRE](https://www.tamtam.ai/c/maire) (groupmaire.com)<br>A technology and engineering group focused on enabling the Energy Transition, offering Sustainable Technology and E&C Solutions in various sectors worldwide | Engineering Services | 🇮🇹 Milan | 3,897 | 2005 |
| 16 | [Valentino](https://www.tamtam.ai/c/valentino) (valentino.com)<br>A luxury fashion house founded in 1960, known for Haute Couture and ready-to-wear lines for women and men, as well as accessories and fragrances | Retail Luxury Goods and Jewelry | 🇮🇹 Milan | 3,864 |  |
| 17 | [Moncler](https://www.tamtam.ai/c/moncler) (monclergroup.com)<br>A fashion brand founded in France in 1952, now based in Italy, known for combining style with mountain-inspired technology in outdoor and urban wear collections | Retail Luxury Goods and Jewelry | 🇮🇹 Milan | 3,838 | 1952 |
| 18 | [Italgas](https://www.tamtam.ai/c/italgas) (italgas.it)<br>A leading Network Tech Company in gas, water, energy efficiency, and IT sectors, providing services to millions of customers in Italy and Greece | Utilities | 🇮🇹 Milan | 3,661 |  |
| 19 | [PROMETEON TYRE GROUP](https://www.tamtam.ai/c/prometeon-tyre-group) (prometeon.com)<br>A tire manufacturer with a focus on industry, transport, AGRO, and OTR applications, offering innovative solutions and embracing diversity | Motor Vehicle Manufacturing | 🇮🇹 Milan | 3,236 | 2017 |
| 20 | [Bolton](https://www.tamtam.ai/c/bolton) (bolton.com)<br>A family-owned multinational producing and distributing over 60 quality brands, committed to making everyday life more enjoyable, beautiful, and delicious, while driving positive change | Manufacturing | 🇮🇹 Milan | 2,786 | 1949 |
| 21 | [Sogefi Group](https://www.tamtam.ai/c/sogefi-group) (sogefigroup.com)<br>A global leader in engine filtration and vehicle suspension components, committed to innovation, research, quality, and environmental sustainability | Motor Vehicle Parts Manufacturing | 🇮🇹 Milan | 2,734 | 1980 |
| 22 | [EPTA GROUP](https://www.tamtam.ai/c/epta-group) (eptarefrigeration.com)<br>Specializes in commercial refrigeration systems and turnkey projects for retail, Ho.Re.Ca, and food sectors with global presence. | Machinery Manufacturing | 🇮🇹 Milan | 1,943 |  |
| 23 | [Bracco](https://www.tamtam.ai/c/bracco) (bracco.com)<br>A leader in healthcare and diagnostic imaging, specializing in contrast agents, medical devices, and innovative solutions across international markets | Pharmaceutical Manufacturing | 🇮🇹 Milan | 1,899 | 1927 |
| 24 | [Olon](https://www.tamtam.ai/c/olon) (olonspa.com)<br>Global leader in developing and producing active pharmaceutical ingredients for CDMO and generics, offering chemical synthesis and biological processing services with extensive expertise and reliability | Chemical Manufacturing | 🇮🇹 Milan | 1,709 | 2003 |
| 25 | [Impresoft Group](https://www.tamtam.ai/c/impresoft-group) (impresoftgroup.com)<br>A group of innovative and leading companies in various industries, offering tailored digital solutions for businesses through agile and scalable approaches | Software Development | 🇮🇹 Milan | 1,588 |  |
| 26 | [Acciaierie d'Italia S.p.A. in A.S.](https://www.tamtam.ai/c/acciaierie-d-italia-s-p-a-in-a-s) (acciaierieditalia.com)<br>An Italian steel company producing sustainable, high-quality steel for various industries in the domestic market and worldwide export | Mining | 🇮🇹 Milan | 1,506 | 2018 |
| 27 | [Libera Università Vita-Salute San Raffaele](https://www.tamtam.ai/c/libera-universita-vita-salute-san-raffaele) (unisr.it)<br>The company is a university focusing on teaching, research, and clinical activities, with a mission centered on understanding and training professionals in human biology, psychology, and spirituality | Higher Education | 🇮🇹 Milan | 1,485 | 1996 |
| 28 | [CESI SpA](https://www.tamtam.ai/c/cesi-spa) (cesi.it)<br>A global technical consulting company specializing in energy sectors such as transmission, renewables, testing, and environmental impact assessments for various clients worldwide | Engineering Services | 🇮🇹 Milan | 1,423 | 1956 |
| 29 | [TAS](https://www.tamtam.ai/c/tas) (tasgroup.eu)<br>Specializing in digital payments, cards, and financial markets, TAS provides secure software solutions worldwide, simplifying business processes and revolutionizing commercial transactions | IT Services and IT Consulting | 🇮🇹 Milan | 1,277 |  |
| 30 | [De Nora](https://www.tamtam.ai/c/de-nora) (denora.com)<br>A multinational company specializing in electrochemistry and sustainable technologies, leading in industrial green hydrogen production, water treatment, and energy efficiency optimization | Industrial Machinery Manufacturing | 🇮🇹 Milan | 1,267 | 1923 |

## How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 11, 2026.

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- [Manufacturers in Milan](https://www.tamtam.ai/l/manufacturers-milan) (103)
- [SaaS companies in Milan](https://www.tamtam.ai/l/saas-companies-milan) (103)
- [Companies with a mobile app in Milan](https://www.tamtam.ai/l/companies-with-mobile-app-milan) (98)
- [Corporate groups and holding companies in Milan](https://www.tamtam.ai/l/holding-companies-milan) (98)
- [E-commerce companies in Milan](https://www.tamtam.ai/l/ecommerce-companies-milan) (90)
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- [Subscription businesses in Milan](https://www.tamtam.ai/l/subscription-businesses-milan) (68)
- [Education providers in Milan](https://www.tamtam.ai/l/education-companies-milan) (63)
- [Retail Luxury Goods and Jewelry companies in Milan](https://www.tamtam.ai/l/retail-luxury-goods-and-jewelry-companies-milan) (63)
- [Consumer goods companies in Milan](https://www.tamtam.ai/l/consumer-goods-companies-milan) (56)

## The same list elsewhere in Italy

- [Companies with in-house R&D in Italy](https://www.tamtam.ai/l/r-and-d-companies-italy) (1,418)
- [Companies with in-house R&D in Lombardy](https://www.tamtam.ai/l/r-and-d-companies-lombardy) (432)
- [Companies with in-house R&D in Emilia-Romagna](https://www.tamtam.ai/l/r-and-d-companies-emilia-romagna) (195)
- [Companies with in-house R&D in Veneto](https://www.tamtam.ai/l/r-and-d-companies-veneto) (182)
- [Companies with in-house R&D in Lazio](https://www.tamtam.ai/l/r-and-d-companies-lazio) (120)
- [Companies with in-house R&D in Piedmont](https://www.tamtam.ai/l/r-and-d-companies-piedmont) (102)
- [Companies with in-house R&D in Tuscany](https://www.tamtam.ai/l/r-and-d-companies-tuscany) (80)
- [Companies with in-house R&D in Campania](https://www.tamtam.ai/l/r-and-d-companies-campania) (44)
- [Companies with in-house R&D in Friuli-Venezia Giulia](https://www.tamtam.ai/l/r-and-d-companies-friuli-venezia-giulia) (43)
- [Companies with in-house R&D in the Marche](https://www.tamtam.ai/l/r-and-d-companies-marche) (34)
- [Companies with in-house R&D in Apulia](https://www.tamtam.ai/l/r-and-d-companies-apulia) (26)
- [Companies with in-house R&D in Trentino-South Tyrol](https://www.tamtam.ai/l/r-and-d-companies-trentino-south-tyrol) (25)
- [Companies with in-house R&D in Rome](https://www.tamtam.ai/l/r-and-d-companies-rome) (82)
- [Companies with in-house R&D in Turin](https://www.tamtam.ai/l/r-and-d-companies-turin) (31)

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Source: https://www.tamtam.ai/l/r-and-d-companies-milan