# The 30 largest companies with in-house R&D in Minneapolis

Tamtam tracks 31 companies with in-house R&D headquartered in Minneapolis. This list ranks the 30 largest by number of employees on LinkedIn, led by Medtronic, General Mills and Xcel Energy. Their median headcount is 431. Half of them were founded in 1975 or later.

This list features companies with in-house R&D based in Minneapolis, predominantly large and mid-sized firms. The selection includes companies like Medtronic, a healthcare technology company, and General Mills, which produces food products. Other notable firms are Xcel Energy, providing energy services, and The Toro Company, which offers equipment and solutions for various outdoor industries.

The companies here represent a mix of established sectors, with a strong presence in manufacturing, particularly medical equipment and industrial machinery. There is also a significant cluster of firms founded in the early to mid-20th century, such as General Mills (1928), Graco (1926), and Daikin Applied Americas (1924).

🇺🇸 Minneapolis · 30 companies · Updated Nov 12, 2026

| # | Company | Industry | Headquarters | Employees | Founded |
|---|---|---|---|---|---|
| 1 | [Medtronic](https://www.tamtam.ai/c/medtronic) (medtronic.com)<br>A healthcare technology company tackling challenging health issues worldwide with innovative solutions that significantly impact and improve lives | Medical Equipment Manufacturing | 🇺🇸 Minneapolis | 100,323 |  |
| 2 | [General Mills](https://www.tamtam.ai/c/general-mills) (generalmills.com)<br>The company is dedicated to creating beloved food products while prioritizing positive impact, learning, innovation, and growth through collaboration and leadership | Manufacturing | 🇺🇸 Minneapolis | 25,309 | 1928 |
| 3 | [Xcel Energy](https://www.tamtam.ai/c/xcel-energy) (xcelenergy.com)<br>providing reliable, resilient, and sustainable energy services to customers across eight states, focusing on excellent service and growth opportunities | Utilities | 🇺🇸 Minneapolis | 12,073 |  |
| 4 | [The Toro Company](https://www.tamtam.ai/c/the-toro-company) (thetorocompany.com)<br>Portfolio of global brands providing innovative equipment and solutions for landscaping, construction, irrigation, and outdoor maintenance industries worldwide. | Machinery Manufacturing | 🇺🇸 Minneapolis | 6,275 |  |
| 5 | [Graco](https://www.tamtam.ai/c/graco) (graco.com)<br>A global leader in fluid handling systems and components, providing technology for fluid management in industrial and commercial settings through innovative products and distribution channels | Machinery Manufacturing | 🇺🇸 Minneapolis | 4,942 | 1926 |
| 6 | [Daikin Applied Americas](https://www.tamtam.ai/c/daikin-applied-americas) (daikinapplied.com)<br>Provides advanced HVAC systems focusing on air quality, energy efficiency, IoT integration, and next-generation compressors through global sales and service network. | Industrial Machinery Manufacturing | 🇺🇸 Minneapolis | 4,833 | 1924 |
| 7 | [Entrust](https://www.tamtam.ai/c/entrust-minneapolis) (entrust.com)<br>Provides identity-centric security solutions, protecting people, devices, data. Fights fraud, cyber threats, secures identity lifecycle, ensures transaction confidence. Global presence, 150 countries. | Software Development | 🇺🇸 Minneapolis | 3,755 |  |
| 8 | [Sleep Number Corporation](https://www.tamtam.ai/c/sleep-number-corporation) (sleepnumber.com)<br>Company improves health and wellbeing through innovative sleep products, operating retail stores, distribution centers, and supporting diverse workforce nationwide. | Retail | 🇺🇸 Minneapolis | 3,632 | 1987 |
| 9 | [Bio-Techne](https://www.tamtam.ai/c/bio-techne) (bio-techne.com)<br>A leading developer and manufacturer of high-quality purified proteins, reagent solutions, diagnostic products, and genomic tools for research and clinical use globally | Biotechnology Research | 🇺🇸 Minneapolis | 2,924 |  |
| 10 | [NMDP](https://www.tamtam.ai/c/nmdp) (nmdp.org)<br>A global non-profit leader in cell therapy, connecting researchers, donors, and clinicians to save lives by finding cures for blood cancers and disorders | Non-profit Organizations | 🇺🇸 Minneapolis | 2,382 | 1987 |
| 11 | [Perforce Software](https://www.tamtam.ai/c/perforce-software) (perforce.com)<br>Leader in digital product development, providing innovative solutions for faster and higher quality output through the power of Perforce technology | Software Development | 🇺🇸 Minneapolis | 2,028 | 1995 |
| 12 | [HealthEast](https://www.tamtam.ai/c/healtheast) (fairview.org)<br>A leading nonprofit healthcare provider in Minnesota offering a full range of services including hospitals, clinics, senior care, rehabilitation, and home health services with compassion | Hospitals and Health Care | 🇺🇸 Minneapolis | 1,830 |  |
| 13 | [Federal Reserve Bank of Minneapolis](https://www.tamtam.ai/c/federal-reserve-bank-of-minneapolis) (minneapolisfed.org)<br>Support national monetary and financial system stability, uphold ethical standards, embrace diversity, and provide development opportunities for workforce excellence. | Banking | 🇺🇸 Minneapolis | 1,047 |  |
| 14 | [University of Minnesota College of Science and Engineering](https://www.tamtam.ai/c/university-of-minnesota-college-of-science-and-engineering) (cse.umn.edu)<br>The organization is the UMN College of Science and Engineering, part of the University of Minnesota, focusing on education and research | Higher Education | 🇺🇸 Minneapolis | 582 | 1935 |
| 15 | [University of Minnesota School of Public Health](https://www.tamtam.ai/c/university-of-minnesota-school-of-public-health) (sph.umn.edu)<br>Top public health school dedicated to researching and solving serious health issues, supporting alumni, students, faculty, and community in improving lives | Higher Education | 🇺🇸 Minneapolis | 431 | 1944 |
| 16 | [MGK](https://www.tamtam.ai/c/mgk) (mgk.com)<br>A family-run company since 1902, specializing in innovative insect control products for consumer, crop-protection, and professional pest control markets globally | Chemical Manufacturing | 🇺🇸 Minneapolis | 387 | 1902 |
| 17 | [Flagstone Foods](https://www.tamtam.ai/c/flagstone-foods) (flagstonefoods.com)<br>Flagstone Foods is a leading private label snacking company in North America, specializing in healthy snacks like nuts, trail mixes, and dried fruits | Food and Beverage Manufacturing | 🇺🇸 Minneapolis | 373 | 2010 |
| 18 | [Minco Products, Inc](https://www.tamtam.ai/c/minco-products-inc) (minco.com)<br>provides advanced engineered solutions combining product technologies, design, and engineering for medical, aerospace, defense, and high-reliability applications worldwide | Appliances, Electrical, and Electronics Manufacturing | 🇺🇸 Minneapolis | 334 | 1956 |
| 19 | [Apogee Enterprises, Inc.](https://www.tamtam.ai/c/apogee-enterprises-inc) (apog.com)<br>Design and manufacture glass and aluminum window, storefront, curtainwall systems, and protective glass products for buildings and framing markets. | Wholesale Building Materials | 🇺🇸 Minneapolis | 286 | 1949 |
| 20 | [Kurt Manufacturing](https://www.tamtam.ai/c/kurt-manufacturing) (kurt.com)<br>We are a driven, innovative company that strives to exceed industry standards and deliver quality products with precision, passion, and loyalty | Machinery Manufacturing | 🇺🇸 Minneapolis | 279 | 1946 |
| 21 | [CVRx \| Barostim](https://www.tamtam.ai/c/cvrx-barostim) (cvrx.com)<br>A medical devices company in Minneapolis, MN, using proprietary implantable technology to treat high blood pressure and heart failure | Medical Equipment Manufacturing | 🇺🇸 Minneapolis | 255 | 2001 |
| 22 | [AWT Labels & Packaging](https://www.tamtam.ai/c/awt-labels-and-packaging) (awtlabelpack.com)<br>A leader in innovative and sustainable solutions for labeling, packaging, and converting, servicing Healthcare, Consumer Brands, and Technology clients worldwide | Printing Services | 🇺🇸 Minneapolis | 217 | 1976 |
| 23 | [University of Minnesota College of Design](https://www.tamtam.ai/c/university-of-minnesota-college-of-design) (design.umn.edu)<br>The College of Design in the Twin Cities offers education, research, and innovation in various design disciplines with a focus on creativity and advancing technologies | Primary and Secondary Education | 🇺🇸 Minneapolis | 216 | 2006 |
| 24 | [ProteinSimple, a Bio-Techne brand](https://www.tamtam.ai/c/proteinsimple-a-bio-techne-brand) (bio-techne.com)<br>Leader in rethinking protein tools with a wide-ranging portfolio including immunoassay and structural analysis systems to help researchers gain new insights into proteins and diseases | Biotechnology Research | 🇺🇸 Minneapolis | 183 | 2004 |
| 25 | [Resolution Medical](https://www.tamtam.ai/c/resolution-medical) (resolutionmedical.com)<br>A company providing innovative business solutions to the medical device industry, focusing on high quality, exceptional customer service, and continuous life improvement | Medical Equipment Manufacturing | 🇺🇸 Minneapolis | 179 | 2012 |
| 26 | [Apothecary Products](https://www.tamtam.ai/c/apothecary-products) (apothecary-brands.com)<br>A consumer products company founded in 1975, focused on self-care and wellness solutions with innovative brands, international presence, and patented products | Consumer Goods | 🇺🇸 Minneapolis | 135 | 1975 |
| 27 | [Omnetics Connector Corporation](https://www.tamtam.ai/c/omnetics-connector-corporation) (omnetics.com)<br>Design and manufacture micro-miniature and nano-miniature high-reliability electronic connectors and interconnection systems for military, aerospace, medical, and high-tech OEMs. | Appliances, Electrical, and Electronics Manufacturing | 🇺🇸 Minneapolis | 128 | 1984 |
| 28 | [AMETEK Paragon Medical](https://www.tamtam.ai/c/ametek-paragon-medical) (paragonmedical.com)<br>A global leader in medical technology design and manufacturing, offering state-of-the-art solutions for clinical applications through custom interconnects, catheter components, and precision laser machining services | Medical Equipment Manufacturing | 🇺🇸 Minneapolis | 117 | 1972 |
| 29 | [Nidec America Corporation](https://www.tamtam.ai/c/nidec-america-corporation)<br>An electrical and electronic manufacturing company headquartered in Minneapolis, specializing in producing a wide range of products | Appliances, Electrical, and Electronics Manufacturing | 🇺🇸 Minneapolis | 50 |  |
| 30 | [Decca Contract Furniture](https://www.tamtam.ai/c/decca-contract-furniture) (deccacontract.com)<br>A luxury furniture manufacturer specializing in high-quality, custom cabinetry with a commitment to sustainability and responsible business practices | Furniture and Home Furnishings Manufacturing | 🇺🇸 Minneapolis | 18 |  |

## How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 12, 2026.

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## The same list elsewhere in United States

- [Companies with in-house R&D in the United States](https://www.tamtam.ai/l/r-and-d-companies-united-states) (6,796)
- [Companies with in-house R&D in California](https://www.tamtam.ai/l/r-and-d-companies-california) (1,275)
- [Companies with in-house R&D in Texas](https://www.tamtam.ai/l/r-and-d-companies-texas) (442)
- [Companies with in-house R&D in New York State](https://www.tamtam.ai/l/r-and-d-companies-new-york-state) (419)
- [Companies with in-house R&D in Massachusetts](https://www.tamtam.ai/l/r-and-d-companies-massachusetts) (396)
- [Companies with in-house R&D in Illinois](https://www.tamtam.ai/l/r-and-d-companies-illinois) (322)
- [Companies with in-house R&D in Michigan](https://www.tamtam.ai/l/r-and-d-companies-michigan) (287)
- [Companies with in-house R&D in Ohio](https://www.tamtam.ai/l/r-and-d-companies-ohio) (277)
- [Companies with in-house R&D in Pennsylvania](https://www.tamtam.ai/l/r-and-d-companies-pennsylvania) (255)
- [Companies with in-house R&D in New Jersey](https://www.tamtam.ai/l/r-and-d-companies-new-jersey) (224)
- [Companies with in-house R&D in Florida](https://www.tamtam.ai/l/r-and-d-companies-florida) (221)
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- [Companies with in-house R&D in Georgia](https://www.tamtam.ai/l/r-and-d-companies-georgia) (173)
- [Companies with in-house R&D in Virginia](https://www.tamtam.ai/l/r-and-d-companies-virginia) (166)
- [Companies with in-house R&D in North Carolina](https://www.tamtam.ai/l/r-and-d-companies-north-carolina) (158)
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## The same list elsewhere

- [Companies with in-house R&D in the world](https://www.tamtam.ai/l/r-and-d-companies-in-the-world) (34,346)
- [Companies with in-house R&D in North America](https://www.tamtam.ai/l/r-and-d-companies-in-north-america) (7,619)

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Source: https://www.tamtam.ai/l/r-and-d-companies-minneapolis
