# Companies with in-house R&D headquartered in Missouri

Tamtam tracks 96 companies with in-house R&D headquartered in Missouri. This list ranks the 50 largest by number of employees on LinkedIn, led by Emerson, Amdocs and University of Missouri-Columbia. Their median headcount is 1,018. Half of them were founded in 1956 or later. The most common headquarters are St. Louis (24), Kansas City (5) and Chesterfield (3).

These Missouri-based companies are largely established enterprises with significant employee numbers, predominantly focused on manufacturing, technology, and healthcare. Many of the featured companies, such as Emerson, Monsanto Company, Nestlé Purina North America, and Anheuser-Busch, are deeply rooted in the state's industrial landscape.

A notable pattern among these companies is their long-standing presence; several were founded in the late 19th or early 20th centuries, indicating a history of sustained operations and development within Missouri. For example, Anheuser-Busch was founded in 1852, Emerson in 1890, and Nestlé Purina North America in 1894.

🇺🇸 Missouri · 50 companies · Updated Nov 12, 2026

| # | Company | Industry | Headquarters | Employees | Founded |
|---|---|---|---|---|---|
| 1 | [Emerson](https://www.tamtam.ai/c/emerson) (emerson.com)<br>A global technology and engineering company providing innovative solutions for industrial and commercial markets, driving innovation for a healthier, safer, and smarter world | Automation Machinery Manufacturing | 🇺🇸 St. Louis | 51,841 | 1890 |
| 2 | [Amdocs](https://www.tamtam.ai/c/amdocs) (amdocs.com)<br>A global company empowers clients to innovate and create exceptional digital experiences, accelerate cloud migration, differentiate in 5G era, and enhance communication and media experiences | Software Development | 🇺🇸 Chesterfield | 34,637 |  |
| 3 | [University of Missouri-Columbia](https://www.tamtam.ai/c/university-of-missouri-columbia) (missouri.edu)<br>State-supported research university providing education, advancing arts, sciences, and professions, focusing on public service and economic development. | Higher Education | 🇺🇸 Columbia | 14,879 |  |
| 4 | [Monsanto Company](https://www.tamtam.ai/c/monsanto-company) (bayer.com)<br>Leading in modern agriculture with a focus on seeds, plant traits, and crop protection through innovative breakthroughs for global impact | Farming | 🇺🇸 St. Louis | 9,303 |  |
| 5 | [Children's Mercy](https://www.tamtam.ai/c/children-s-mercy) (childrensmercy.org)<br>Specialized pediatric healthcare provider focusing on exceptional care, innovative research, and education to improve children's health and well-being. | Hospitals and Health Care | 🇺🇸 Kansas City | 8,393 | 1897 |
| 6 | [Nestlé Purina North America](https://www.tamtam.ai/c/nestle-purina-north-america) (purinajobs.com)<br>Advances pet nutrition science, collaborates on innovation, and enriches lives of pets and owners. Builds strong teams for pet care. | Manufacturing | 🇺🇸 St. Louis | 8,321 | 1894 |
| 7 | [Anheuser-Busch](https://www.tamtam.ai/c/anheuser-busch) (anheuser-busch.com)<br>A leading brewer in the United States with a legacy of crafting high-quality beers, supporting communities, and valuing talented employees | Food and Beverage Services | 🇺🇸 St. Louis | 7,091 | 1852 |
| 8 | [Nidec Motor Corporation](https://www.tamtam.ai/c/nidec-motor-corporation) (acim.nidec.com)<br>manufacture high efficiency commercial and industrial motors, controls, and generators for applications in water treatment, mining, oil, gas, and refrigeration | Appliances, Electrical, and Electronics Manufacturing | 🇺🇸 Creve Coeur | 5,082 |  |
| 9 | [Copeland](https://www.tamtam.ai/c/copeland) (copeland.com)<br>Develop sustainable HVACR technologies for residential, commercial, and industrial spaces, ensuring cold chain integrity and global comfort. | Climate Technology Product Manufacturing | 🇺🇸 St. Louis | 4,804 |  |
| 10 | [EquipmentShare](https://www.tamtam.ai/c/equipmentshare) (equipmentshare.com)<br>A nationwide equipment and digital solutions company empowering construction industry with technology platform, equipment rental, retail, and service solutions | Construction | 🇺🇸 Columbia | 4,193 | 2014 |
| 11 | [Sigma-Aldrich](https://www.tamtam.ai/c/sigma-aldrich) (bit.ly)<br>Providing scientists with lab materials, technologies, and services to simplify, accelerate, and improve life science research and biotech production worldwide. | Biotechnology Research | 🇺🇸 St. Louis | 3,467 | 1951 |
| 12 | [Missouri University of Science and Technology](https://www.tamtam.ai/c/missouri-university-of-science-and-technology) (mst.edu)<br>A prestigious technological research university offering degrees in engineering, science, business, IT, humanities, and education with a focus on technological literacy | Higher Education | 🇺🇸 Rolla | 3,410 |  |
| 13 | [Hussmann](https://www.tamtam.ai/c/hussmann) (hussmann.com)<br>A global leader in providing innovative display cases and refrigeration systems, Hussmann focuses on improving food retailing with value-added solutions and services since 1906 | Retail Groceries | 🇺🇸 Bridgeton | 3,148 |  |
| 14 | [Watlow](https://www.tamtam.ai/c/watlow) (watlow.com)<br>Global industrial technology company, expertise in thermal systems, providing temperature control, power control, heater technologies, and temperature sensing platforms to various industries. | Industrial Machinery Manufacturing | 🇺🇸 St. Louis | 2,840 | 1922 |
| 15 | [Par Health](https://www.tamtam.ai/c/par-health) (parhealth.com)<br>Manufactures generic medicines, active pharmaceutical ingredients, and sterile injectables across multiple therapeutic areas, providing essential healthcare solutions for patients and providers. | Pharmaceutical Manufacturing | 🇺🇸 St Louis | 2,196 | 1978 |
| 16 | [SSM Health Saint Louis University Hospital](https://www.tamtam.ai/c/ssm-health-saint-louis-university-hospital) (ssmhealth.com)<br>An academic medical center affiliated with Saint Louis University School of Medicine, offering cutting-edge treatments, research, and compassionate care to patients | Hospitals and Health Care | 🇺🇸 St. Louis | 1,563 |  |
| 17 | [Hunter Engineering Company](https://www.tamtam.ai/c/hunter-engineering-company) (hunter.com)<br>Global leader in automotive service equipment with innovative wheel alignment systems, balancers, tire changers, inspection equipment, brake lathes, and patented features for efficient undercar service | Motor Vehicle Manufacturing | 🇺🇸 Bridgeton | 1,535 | 1946 |
| 18 | [EyeCare Partners](https://www.tamtam.ai/c/eyecare-partners) (eyecare-partners.com)<br>EyeCare Partners is dedicated to reinventing eye care by uniting optometry and ophthalmology practices to provide high-quality, accessible, and personalized vision health solutions nationwide | Hospitals and Health Care | 🇺🇸 St. Louis | 1,457 | 2015 |
| 19 | [Silgan Plastics](https://www.tamtam.ai/c/silgan-plastics) (silganplastics.com)<br>Silgan Plastics offers innovative and customized packaging solutions, from design to production, to help clients achieve packaging success | Plastics Manufacturing | 🇺🇸 Chesterfield | 1,397 | 1987 |
| 20 | [Herzog](https://www.tamtam.ai/c/herzog) (herzog.com)<br>A leading industry expert in railroad construction, maintenance, and operations with in-house equipment design for data-driven operational decisions | Construction | 🇺🇸 St Joseph | 1,356 | 1969 |
| 21 | [Vegetables by Bayer](https://www.tamtam.ai/c/vegetables-by-bayer) (vegetables.bayer.com)<br>A St Louis-based food production company specializing in vegetable seeds, part of Bayer CropScience | Farming | 🇺🇸 St. Louis | 1,354 |  |
| 22 | [Lumeris](https://www.tamtam.ai/c/lumeris) (lumeris.com)<br>Value-based care managed services operator aligning providers and payers to achieve high-quality, cost-effective care with satisfied consumers and engaged physicians | Hospitals and Health Care | 🇺🇸 Maryland Heights | 1,149 | 2012 |
| 23 | [Arch Resources, Inc](https://www.tamtam.ai/c/arch-resources-inc) (corenaturalresources.com)<br>Producer and exporter of metallurgical and thermal coals, operating multiple mines and marine export terminals focused on seaborne markets. | Mining | 🇺🇸 St. Louis | 1,136 |  |
| 24 | [Kansas City University](https://www.tamtam.ai/c/kansas-city-university) (kansascity.edu)<br>A private university offering programs in osteopathic medicine, dental medicine, biosciences, and clinical psychology, known for academic excellence and hands-on learning opportunities | Higher Education | 🇺🇸 Kansas City | 1,122 | 1916 |
| 25 | [Kansas City National Security Campus](https://www.tamtam.ai/c/kansas-city-national-security-campus) (kcnsc.doe.gov)<br>An advanced engineering and manufacturing facility dedicated to ensuring the safety and security of our country's nuclear deterrence | Defense and Space Manufacturing | 🇺🇸 Kansas City | 1,018 | 1949 |
| 26 | [MLC](https://www.tamtam.ai/c/mlc) (mlc.com)<br>A leading supplier of high-quality lime products, calcium carbonate, and technical solutions with a strong focus on customer satisfaction and reliable distribution network | Chemical Manufacturing | 🇺🇸 St. Louis | 1,010 | 1907 |
| 27 | [Nestlé Purina Latin America & Caribbean](https://www.tamtam.ai/c/nestle-purina-latin-america-and-caribbean) (nestle.com)<br>This company focuses on enhancing the lives of pets and their owners through nutritious food sourced responsibly, with a portfolio of recognized brands | Manufacturing | 🇺🇸 St. Louis | 999 |  |
| 28 | [LMI Aerospace - A Member of the Sonaca Group](https://www.tamtam.ai/c/lmi-aerospace-a-member-of-the-sonaca-group) (sonaca.com)<br>Designing, building, and manufacturing aerospace structures, systems, and components for commercial, business, regional, and military aerospace industries. | Aviation and Aerospace Component Manufacturing | 🇺🇸 St. Charles | 905 | 1948 |
| 29 | [PROENERGY](https://www.tamtam.ai/c/proenergy) (proenergyservices.com)<br>Integrated service provider delivering cost-effective, safe, and reliable solutions to the global energy industry with offices in multiple countries | Fossil Fuel Electric Power Generation | 🇺🇸 Sedalia | 866 | 2002 |
| 30 | [SSM Health Cardinal Glennon Children's Hospital](https://www.tamtam.ai/c/ssm-health-cardinal-glennon-children-s-hospital) (ssmhealth.com)<br>A non-profit Catholic pediatric hospital providing high-quality care to children with complex conditions, located in St Louis, MO | Hospitals and Health Care | 🇺🇸 St. Louis | 824 | 1956 |
| 31 | [Saint Louis Zoo](https://www.tamtam.ai/c/saint-louis-zoo) (stlzoo.org)<br>A world-renowned zoo with over 16,000 animals and 500 species, focusing on animal care, wildlife conservation, research, and education | Museums, Historical Sites, and Zoos | 🇺🇸 St. Louis | 793 | 1910 |
| 32 | [Pretium Packaging](https://www.tamtam.ai/c/pretium-packaging) (pretiumpkg.com)<br>Plastic container manufacturer specializing in sustainable packaging for food, beverage, healthcare, personal care, and more with custom design capabilities | Packaging and Containers Manufacturing | 🇺🇸 St. Louis | 760 |  |
| 33 | [Anchor Packaging](https://www.tamtam.ai/c/anchor-packaging) (anchorpackaging.com)<br>A leading thermoform packaging producer in North America, specializing in custom designs for foodservice industry with a focus on sustainability and innovation | Packaging and Containers Manufacturing | 🇺🇸 St. Louis | 698 | 1963 |
| 34 | [Fike Corporation](https://www.tamtam.ai/c/fike-corporation) (fike.com)<br>Designs and manufactures rupture discs, explosion protection, fire alarm, and suppression systems for global businesses seeking disaster prevention and safety assurance. | Engineering Services | 🇺🇸 Blue Springs | 692 | 1945 |
| 35 | [SunEdison Semiconductor](https://www.tamtam.ai/c/sunedison-semiconductor) (gw-semi.com)<br>Global leader in semiconductor technology, providing silicon wafers for electronic devices and industrial applications, serving top chip manufacturers worldwide since 1959 | Semiconductor Manufacturing | 🇺🇸 St. Peters | 674 | 1959 |
| 36 | [The Doe Run Company](https://www.tamtam.ai/c/the-doe-run-company) (doerun.com)<br>A privately held natural resources company in St Louis, USA, providing lead, copper, and zinc concentrates, with a focus on environmentally responsible mineral production and recycling | Mining | 🇺🇸 St. Louis | 546 | 1994 |
| 37 | [CST Industries, Inc.](https://www.tamtam.ai/c/cst-industries-inc) (cstindustries.com)<br>Global leader in manufacturing factory coated metal storage tanks, aluminum domes, and specialty covers with a worldwide presence in various industries | Machinery Manufacturing | 🇺🇸 Kansas City | 540 | 1893 |
| 38 | [Vi-Jon](https://www.tamtam.ai/c/vi-jon) (vijon.com)<br>A provider of private brand dry goods bath and personal care products, including Epsom salts and other personal care items | Manufacturing | 🇺🇸 St. Louis | 523 | 2020 |
| 39 | [EaglePicher Technologies](https://www.tamtam.ai/c/eaglepicher-technologies) (eaglepicher.com)<br>Leading producer of batteries and energetic devices. Serving mission-critical aerospace, defense, and aviation battery markets for over 80 years. Provides power solutions. | Defense and Space Manufacturing | 🇺🇸 Joplin | 518 | 1843 |
| 40 | [The Gund Company](https://www.tamtam.ai/c/the-gund-company) (thegundcompany.com)<br>Custom engineered material solutions provider, manufacturing and fabricating parts worldwide. Material specialists offer consultative services, optimizing production for efficiency and cost reduction. | Appliances, Electrical, and Electronics Manufacturing | 🇺🇸 St. Louis | 505 | 1951 |
| 41 | [White River Marine Group](https://www.tamtam.ai/c/white-river-marine-group) (whiterivermg.com)<br>The company is a leading manufacturer of fishing and recreational boats, ATVs, side-by-sides, kayaks, and provides financing solutions for outdoor recreational products | Maritime Transportation | 🇺🇸 Springfield | 473 | 1978 |
| 42 | [Brewer Science](https://www.tamtam.ai/c/brewer-science) (brewerscience.com)<br>A global leader in developing innovative materials, processes, and equipment for cutting-edge microdevices used in electronics, specializing in advanced lithography and nanotechnology | Semiconductor Manufacturing | 🇺🇸 Rolla | 447 | 1981 |
| 43 | [University of Missouri-Columbia, School of Medicine](https://www.tamtam.ai/c/university-of-missouri-columbia-school-of-medicine) (medicine.missouri.edu)<br>An academic health system dedicated to patient care, research, and education, serving patients from all Missouri counties and training future healthcare providers | Higher Education | 🇺🇸 Columbia | 431 |  |
| 44 | [Schaeffer Mfg. Company](https://www.tamtam.ai/c/schaeffer-mfg-company) (schaefferoil.com)<br>Family-owned company delivering specialized lubricant solutions for equipment challenges, enhancing engine durability, fuel economy, and overall equipment efficiency for customers. | Oil and Gas | 🇺🇸 St. Louis | 431 | 1839 |
| 45 | [Exegy](https://www.tamtam.ai/c/exegy) (exegy.com)<br>Global leader in market data and trading technology, offering fully managed solutions powered by cutting-edge hardware, AI, and service automation technologies worldwide | Financial Services | 🇺🇸 St. Louis | 423 | 2003 |
| 46 | [Alpha Packaging](https://www.tamtam.ai/c/alpha-packaging) (alphap.com)<br>Manufacturer of plastic bottles and jars for various industries worldwide, offering stock and custom PET and HDPE containers in sizes up to 1 gallon | Plastics Manufacturing | 🇺🇸 St. Louis | 411 | 1969 |
| 47 | [Spartech LLC](https://www.tamtam.ai/c/spartech-llc) (spartech.com)<br>Develops custom engineered plastic sheet and rollstock solutions for diverse industries, offering various materials, specializing in thermoforming, medical, military, and packaging applications. | Plastics Manufacturing | 🇺🇸 St. Louis | 407 | 1960 |
| 48 | [ALTOR](https://www.tamtam.ai/c/altor) (altorsolutions.com)<br>Innovative company revolutionizing Life Sciences and Engineered Transport Solutions industries with extensive manufacturing and distribution network in US and Mexico | Packaging and Containers Manufacturing | 🇺🇸 Chesterfield | 403 | 1957 |
| 49 | [AFB International](https://www.tamtam.ai/c/afb-international) (afbinternational.com)<br>A global leader creating high-quality palatability enhancers for pet food Enhancing taste and providing essential nutrients for companion animals worldwide | Food and Beverage Manufacturing | 🇺🇸 St. Charles | 394 | 1986 |
| 50 | [Butler Manufacturing](https://www.tamtam.ai/c/butler-manufacturing) (butlermfg.com)<br>Innovative construction company offering design, manufacturing, and construction services to reduce total building operating costs and provide sustainable, high-quality buildings | Wholesale Building Materials | 🇺🇸 Kansas City | 375 | 1901 |

## How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 12, 2026.

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Source: https://www.tamtam.ai/l/r-and-d-companies-missouri