# Top 50 companies with in-house R&D in North Carolina

Tamtam tracks 158 companies with in-house R&D headquartered in North Carolina. This list ranks the 50 largest by number of employees on LinkedIn, led by IQVIA, Collins Aerospace and Lenovo. Their median headcount is 5,907. Half of them were founded in 1970 or later. The most common headquarters are Charlotte (13), Durham (11) and Raleigh (7).

This selection of companies with in-house R&D in North Carolina reveals a strong presence of large organizations, particularly in the healthcare and technology sectors. Companies like IQVIA and Labcorp, both in Hospitals and Health Care, employ tens of thousands, providing clinical research, laboratory services, and healthcare intelligence. Other significant players include Lenovo, a global technology powerhouse, and Collins Aerospace, delivering connected solutions for aviation.

A notable pattern among these companies is the concentration of headquarters in a few key cities. Charlotte emerges as a prominent hub, hosting Advocate Health, Atrium Health, and Duke Energy Corporation, which focuses on utilities and clean energy transition. Raleigh also features prominently with Red Hat, an enterprise open source solutions leader, and North Carolina State University, specializing in STEM education.

🇺🇸 North Carolina · 50 companies · Updated Nov 11, 2026

| # | Company | Industry | Headquarters | Employees | Founded |
|---|---|---|---|---|---|
| 1 | [IQVIA](https://www.tamtam.ai/c/iqvia) (iqvia.com)<br>Provides clinical research, commercial insights, and healthcare intelligence to life sciences and healthcare industries, accelerating medical treatments for better patient outcomes. | Hospitals and Health Care | 🇺🇸 Durham | 80,633 | 1954 |
| 2 | [Collins Aerospace](https://www.tamtam.ai/c/collins-aerospace) (rtx.com)<br>Global aerospace company designing and delivering connected solutions for passenger safety, mission success, space exploration, and operational efficiency. | Aviation and Aerospace Component Manufacturing | 🇺🇸 Charlotte | 51,969 |  |
| 3 | [Lenovo](https://www.tamtam.ai/c/lenovo) (lenovo.com)<br>A global technology powerhouse with a focus on delivering smarter technology through innovation, serving millions of customers worldwide in various markets | IT Services and IT Consulting | 🇺🇸 Morrisville | 47,094 | 1984 |
| 4 | [Labcorp](https://www.tamtam.ai/c/labcorp) (labcorp.com)<br>Provides innovative, comprehensive laboratory services, insights, and advanced science to improve health outcomes and develop new drugs for global clients and patients. | Hospitals and Health Care | 🇺🇸 Burlington | 42,780 | 1905 |
| 5 | [Advocate Health](https://www.tamtam.ai/c/advocate-health) (advocatehealth.org)<br>Advocate Health redefines care delivery to help people live well by providing equitable services across six states for better outcomes at lower costs | Hospitals and Health Care | 🇺🇸 Charlotte | 34,037 |  |
| 6 | [Atrium Health](https://www.tamtam.ai/c/atrium-health) (atriumhealth.org)<br>Nationally recognized health leader providing innovative research, education, and compassionate patient care through top-ranked specialties, medical education, and community benefits | Hospitals and Health Care | 🇺🇸 Charlotte | 30,465 | 1940 |
| 7 | [Duke Energy Corporation](https://www.tamtam.ai/c/duke-energy-corporation) (duke-energy.com)<br>Electric and natural gas utilities serving millions, focusing on clean energy transition, grid upgrades, and net-zero emissions goals. | Utilities | 🇺🇸 Charlotte | 25,788 |  |
| 8 | [Red Hat](https://www.tamtam.ai/c/red-hat) (redhat.com)<br>A global leader in enterprise open source solutions, delivering high-performing Linux, hybrid cloud, edge, and Kubernetes technologies through community collaboration Join us and make an impact | Software Development | 🇺🇸 Raleigh | 21,000 | 1993 |
| 9 | [North Carolina State University](https://www.tamtam.ai/c/north-carolina-state-university) (ncsu.edu)<br>Comprehensive university specializing in STEM education and research, committed to improving quality of life locally and globally through innovation. | Higher Education | 🇺🇸 Raleigh | 20,729 | 1887 |
| 10 | [SAS](https://www.tamtam.ai/c/sas) (sas.com)<br>A trusted analytics partner providing fast and productive AI solutions, empowering customers worldwide with the power to generate insights quickly | Software Development | 🇺🇸 Cary | 18,697 | 1976 |
| 11 | [Sealed Air Corporation](https://www.tamtam.ai/c/sealed-air-corporation) (sealedair.com)<br>Development and supply of automated, sustainable packaging solutions protecting food, liquids, and goods, enhancing e-commerce and reducing environmental impact. | Packaging and Containers Manufacturing | 🇺🇸 Charlotte | 17,000 |  |
| 12 | [Duke University](https://www.tamtam.ai/c/duke-university) (duke.edu)<br>Private research university offering undergraduate, graduate, and professional education with strong emphasis on research and academic excellence. | Higher Education | 🇺🇸 Durham | 16,307 | 1924 |
| 13 | [Ingersoll Rand](https://www.tamtam.ai/c/ingersoll-rand) (irco.com)<br>Provider of durable, high-performance industrial flow creation and solutions, supporting complex environments with expertise and productivity. | Industrial Machinery Manufacturing | 🇺🇸 Davidson | 15,367 |  |
| 14 | [Trane Technologies](https://www.tamtam.ai/c/trane-technologies) (tranetechnologies.com)<br>This company challenges industry norms, commits to ambitious sustainability goals, and aims to influence global change through innovative solutions for heating, cooling, and refrigeration | Industrial Machinery Manufacturing | 🇺🇸 Davidson | 15,027 |  |
| 15 | [Duke University Health System](https://www.tamtam.ai/c/duke-university-health-system) (dukehealth.org)<br>Academic health system focused on innovative research, education, evidence-based medicine, community health improvement, and eliminating health disparities globally and locally. | Hospitals and Health Care | 🇺🇸 Durham | 12,096 |  |
| 16 | [Epic Games](https://www.tamtam.ai/c/epic-games) (epicgames.com)<br>Provider of 3D engine technology powering games and industries, operator of Fortnite, and digital ecosystem for developers and creators. | Computer Games | 🇺🇸 Cary | 11,831 |  |
| 17 | [Atrium Health Wake Forest Baptist](https://www.tamtam.ai/c/atrium-health-wake-forest-baptist) (wakehealth.edu)<br>Academic medical center with hospitals, clinics, medical school, research, and community health services providing extensive patient care and education. | Hospitals and Health Care | 🇺🇸 Winston-Salem | 11,679 |  |
| 18 | [Dentsply Sirona](https://www.tamtam.ai/c/dentsply-sirona) (dentsplysirona.com)<br>World's largest maker of professional dental products and technologies, enabling dental professionals to offer improved, safer, and quicker dental care. Comprehensive solutions across consumables, equipment, technology, specialty products. | Medical Equipment Manufacturing | 🇺🇸 Charlotte | 11,331 | 1899 |
| 19 | [Labcorp Drug Development](https://www.tamtam.ai/c/labcorp-drug-development) (labcorp.com)<br>A global leader in diagnostics and drug development, providing insights to improve health and lives through innovative solutions and unparalleled capabilities | Hospitals and Health Care | 🇺🇸 Burlington | 9,425 |  |
| 20 | [FHI 360](https://www.tamtam.ai/c/fhi-360) (fhi360.org)<br>Nonprofit organization advancing equity, health, and well-being worldwide through research, resources, and locally led, data-driven solutions. | International Trade and Development | 🇺🇸 Durham | 8,644 | 1971 |
| 21 | [East Carolina University](https://www.tamtam.ai/c/east-carolina-university) (ecu.edu)<br>Educates North Carolina residents, conducts research, and provides community service, preparing future workforce leaders through academic programs and partnerships, especially in eastern North Carolina. | Higher Education | 🇺🇸 Greenville | 8,642 | 1907 |
| 22 | [RTI International](https://www.tamtam.ai/c/rti-international) (rti.org)<br>Independent scientific research institute providing technical, social, statistical, and engineering expertise to solve critical global challenges and improve human conditions. | Research Services | 🇺🇸 Research Triangle Park | 6,607 | 1958 |
| 23 | [Vontier](https://www.tamtam.ai/c/vontier) (vontier.com)<br>A global industrial technology company specializing in smarter transportation, mobility technologies, fueling, fleet management, telematics, vehicle diagnostics, and smart cities solutions | Transportation Equipment Manufacturing | 🇺🇸 Raleigh | 6,201 | 2020 |
| 24 | [Ralliant](https://www.tamtam.ai/c/ralliant) (ralliant.com)<br>Design, develop, and deliver high-performance instruments and solutions enabling engineers to innovate and accelerate advanced product development worldwide. | Electrical Equipment Manufacturing | 🇺🇸 Raleigh | 6,173 |  |
| 25 | [FUJIFILM Biotechnologies](https://www.tamtam.ai/c/fujifilm-biotechnologies) (fujifilm.com)<br>Accelerates biopharma progress, expands capabilities, streamlines processes, and strengthens innovation for cures, vaccines, and biologics, improving patient outcomes worldwide. | Biotechnology Research | 🇺🇸 Billingham | 5,907 | 2011 |
| 26 | [Curtiss-Wright Corporation](https://www.tamtam.ai/c/curtiss-wright-corporation) (curtisswright.com)<br>Global manufacturer providing highly engineered products and advanced technology solutions for critical functions within international commercial, industrial, defense, and energy market sectors. | Defense and Space Manufacturing | 🇺🇸 Davidson | 5,835 |  |
| 27 | [Avalara](https://www.tamtam.ai/c/avalara) (avalara.com)<br>Provides an agentic AI platform for global tax and compliance, automating calculations, return filings, and exemption certificate management for businesses worldwide. | Software Development | 🇺🇸 Durham | 5,649 | 2004 |
| 28 | [University of North Carolina Wilmington](https://www.tamtam.ai/c/university-of-north-carolina-wilmington) (uncw.edu)<br>A coastal university emphasizing teaching, research, and service, offering a range of baccalaureate, master's, and doctoral programs with a focus on student engagement and diversity | Higher Education | 🇺🇸 Wilmington | 5,547 | 1947 |
| 29 | [JELD-WEN, Inc.](https://www.tamtam.ai/c/jeld-wen-inc) (corporate.jeld-wen.com)<br>designs manufactures distributes high-performance interior exterior doors windows related building products for new construction repair remodeling sectors | Wholesale Building Materials | 🇺🇸 Charlotte | 5,204 | 1960 |
| 30 | [Albemarle Corporation](https://www.tamtam.ai/c/albemarle-corporation) (albemarle.com)<br>A global leader in transforming essential resources into mobility, energy, connectivity, and health solutions with a focus on sustainability and innovation | Chemical Manufacturing | 🇺🇸 Charlotte | 4,300 |  |
| 31 | [SPX FLOW, Inc.](https://www.tamtam.ai/c/spx-flow-inc) (spxflow.com)<br>manufacturing and delivering technology, service, and support to nutrition, health, and industrial sectors for efficient manufacturing processes | Industrial Machinery Manufacturing | 🇺🇸 Charlotte | 4,154 | 2015 |
| 32 | [Extreme Networks](https://www.tamtam.ai/c/extreme-networks) (extremenetworks.com)<br>Leader in AI-powered cloud networking, delivering a unified platform simplifying and securing IT operations, connecting devices, applications, and users for thousands of customers. | Software Development | 🇺🇸 Morrisville | 4,064 | 1996 |
| 33 | [UTC Aerospace Systems](https://www.tamtam.ai/c/utc-aerospace-systems) (collinsaerospace.com)<br>The company designs and manufactures aerospace systems that power, control, and monitor aircraft, enabling modern flight and technological innovation worldwide | Aviation and Aerospace Component Manufacturing | 🇺🇸 Charlotte | 4,046 | 2012 |
| 34 | [Novolex](https://www.tamtam.ai/c/novolex) (novolex.com)<br>Leader in packaging innovation and sustainability, offering products in paper, plastic, and sustainable materials for food, retail, health, and industrial markets | Packaging and Containers Manufacturing | 🇺🇸 Charlotte | 3,879 | 2004 |
| 35 | [Duke University Hospital](https://www.tamtam.ai/c/duke-university-hospital)<br>A leading academic medical center known for exceptional care, groundbreaking research, and commitment to improving the health of individuals and communities | Hospitals and Health Care | 🇺🇸 Durham | 3,704 | 1925 |
| 36 | [Kontoor Brands, Inc.](https://www.tamtam.ai/c/kontoor-brands-inc) (kontoorbrands.com)<br>Portfolio management of iconic lifestyle, outdoor, and workwear brands including Wrangler, Lee, and Helly Hansen. | Retail Apparel and Fashion | 🇺🇸 Greensboro | 3,283 | 2019 |
| 37 | [Merz Aesthetics](https://www.tamtam.ai/c/merz-aesthetics) (merzaesthetics.com)<br>A global medical aesthetics business offering injectables, devices, and skincare treatments to help individuals look, feel, and live confidently worldwide | Pharmaceutical Manufacturing | 🇺🇸 Raleigh | 3,164 |  |
| 38 | [Center for Creative Leadership](https://www.tamtam.ai/c/center-for-creative-leadership) (ccl.org)<br>A global leader in executive education, using research to develop individuals and organizations into better leaders across the world | Professional Training and Coaching | 🇺🇸 Greensboro | 2,969 | 1970 |
| 39 | [University of North Carolina System](https://www.tamtam.ai/c/university-of-north-carolina-system) (northcarolina.edu)<br>A multi-campus university system in North Carolina dedicated to teaching, research, outreach, and service with over 225,000 students enrolled | Higher Education | 🇺🇸 Raleigh | 2,948 | 1776 |
| 40 | [Goodrich](https://www.tamtam.ai/c/goodrich) (goodrich.com)<br>A global supplier to aerospace, defense, and homeland security markets with a diversified product portfolio, serving customers worldwide with innovative systems and services | Aviation and Aerospace Component Manufacturing | 🇺🇸 Charlotte | 2,616 | 1870 |
| 41 | [Duke University School of Medicine](https://www.tamtam.ai/c/duke-university-school-of-medicine) (medschool.duke.edu)<br>Leading medical school with a focus on interdisciplinary collaboration, research, and innovation to improve human health locally and globally | Higher Education | 🇺🇸 Durham | 2,542 | 1930 |
| 42 | [Toshiba Global Commerce Solutions](https://www.tamtam.ai/c/toshiba-global-commerce-solutions) (commerce.toshiba.com)<br>Global leader in retail store technology, providing integrated in-store solutions that enhance customer engagement, transform the in-store experience, and accelerate digital transformation | Technology, Information and Internet | 🇺🇸 Durham | 2,537 | 2012 |
| 43 | [Wolfspeed](https://www.tamtam.ai/c/wolfspeed) (wolfspeed.com)<br>Global leader in Silicon Carbide technology for over 30 years, enabling breakthroughs in electric vehicles, 5G, renewable energy, aerospace, and defense industries | Semiconductor Manufacturing | 🇺🇸 Durham | 2,460 | 2015 |
| 44 | [Parker Lord](https://www.tamtam.ai/c/parker-lord) (parker.com)<br>Global leader in motion and control technologies serving industrial and aerospace markets with diverse products for manufacturing, transportation, and infrastructure | Industrial Machinery Manufacturing | 🇺🇸 Cary | 2,455 | 1924 |
| 45 | [N-able](https://www.tamtam.ai/c/n-able-morrisville) (n-able.com)<br>Protects businesses from cyberthreats with a unified cyber resiliency platform. Manages, secures, and recovers data using AI-powered technology and partner support. | Computer and Network Security | 🇺🇸 Morrisville | 2,289 |  |
| 46 | [insightsoftware](https://www.tamtam.ai/c/insightsoftware) (insightsoftware.com)<br>Global provider of reporting, analytics, and performance management solutions empowering finance teams with insights to make informed decisions and drive financial intelligence | Software Development | 🇺🇸 Raleigh | 2,267 |  |
| 47 | [Mack Trucks](https://www.tamtam.ai/c/mack-trucks) (linktr.ee)<br>Designs, builds, and delivers tools and services for business success since 1900 Dedicated to personal relationships, industry expertise, and long-lasting value Born Ready | Truck Transportation | 🇺🇸 Greensboro | 2,108 | 1900 |
| 48 | [Columbus McKinnon](https://www.tamtam.ai/c/columbus-mckinnon) (columbusmckinnon.com)<br>A global leader in intelligent motion solutions, offering high-quality brands for increasing safety, improving productivity, and moving the world forward | Machinery Manufacturing | 🇺🇸 Charlotte | 1,807 | 1875 |
| 49 | [KBI Biopharma](https://www.tamtam.ai/c/kbi-biopharma) (kbibiopharma.com)<br>Provides fully-integrated, accelerated drug development and biomanufacturing services to pharmaceutical and biotechnology companies globally with world-class analytical capabilities. | Biotechnology Research | 🇺🇸 Durham | 1,694 | 1996 |
| 50 | [Cree](https://www.tamtam.ai/c/cree) (wolfspeed.com)<br>Specializing in Silicon Carbide technology, we provide cutting-edge solutions and innovations Follow us at Wolfspeed, Inc for the latest updates | Semiconductor Manufacturing | 🇺🇸 Durham | 1,658 | 1987 |

## How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 11, 2026.

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Source: https://www.tamtam.ai/l/r-and-d-companies-north-carolina