# List of companies with in-house R&D in Overijssel

Tamtam tracks 41 companies with in-house R&D headquartered in Overijssel. This list ranks all of them by number of employees on LinkedIn, led by University of Twente, Saxion University of Applied Sciences and Windesheim. Their median headcount is 317. Half of them were founded in 1986 or later. The most common headquarters are Enschede (13), Deventer (4) and Zwolle (4).

The Overijssel region shows a strong presence of higher education and machinery manufacturing companies with in-house R&D. Key players include the University of Twente, conducting cutting-edge research, and Saxion University of Applied Sciences, offering Bachelor and Master programs. Medisch Spectrum Twente is a top clinical hospital, while Tembo Group provides manufacturing solutions for sustainable alternatives. ITM specializes in solutions for the tobacco industry, and Topicus develops IT solutions for healthcare, education, and finance.

A notable pattern is the concentration of headquarters in Enschede, which hosts several significant institutions like the University of Twente, Saxion University of Applied Sciences, Medisch Spectrum Twente, and Demcon, a firm that develops innovative and complex systems. This indicates a hub for research, education, and advanced engineering within the region.

🇳🇱 Overijssel · 41 companies · Updated Nov 11, 2026

| # | Company | Industry | Headquarters | Employees | Founded |
|---|---|---|---|---|---|
| 1 | [University of Twente](https://www.tamtam.ai/c/university-of-twente) (utwente.nl)<br>A forward-thinking university with 3,300 professionals conducting cutting-edge research, driving innovation, and providing inspiring education for over 12,000 students | Research Services | 🇳🇱 Enschede | 5,632 | 1961 |
| 2 | [Saxion University of Applied Sciences](https://www.tamtam.ai/c/saxion-university-of-applied-sciences) (saxion.nl)<br>A university of applied sciences in the Netherlands offering Bachelor and Master programs, short courses, and preparatory courses in English to local and international students | Higher Education | 🇳🇱 Enschede / Deventer / Apeldoorn | 4,348 | 1998 |
| 3 | [Windesheim](https://www.tamtam.ai/c/windesheim) (windesheim.nl)<br>Provides practice-oriented higher education with 87 study programs, emphasizing international elements and welcoming foreign students and lecturers. | Higher Education | 🇳🇱 Zwolle | 3,800 | 1986 |
| 4 | [Medisch Spectrum Twente](https://www.tamtam.ai/c/medisch-spectrum-twente) (mst.nl)<br>A top clinical hospital in Twente offering a wide range of healthcare services, medical education, research, trauma care, and collaboration within a network of hospitals | Hospitals and Health Care | 🇳🇱 Enschede | 2,709 |  |
| 5 | [Tembo Group](https://www.tamtam.ai/c/tembo-group) (tembo.eu)<br>A global family business with a focus on sustainability, providing manufacturing solutions for sustainable alternatives and innovative cross-over products | Machinery Manufacturing | 🇳🇱 Kampen | 1,083 | 1912 |
| 6 | [ITM](https://www.tamtam.ai/c/itm-kampen) (tembo.eu)<br>The company specializes in providing comprehensive solutions for the tobacco industry, focusing on high-volume, high-precision platforms for efficient production of innovative products | Machinery Manufacturing | 🇳🇱 Kampen | 916 |  |
| 7 | [Topicus](https://www.tamtam.ai/c/topicus) (topicus.nl)<br>The company develops user-friendly IT solutions that benefit healthcare, education, finance, and social sectors, aiming to empower citizens and reduce vulnerability | IT Services and IT Consulting | 🇳🇱 Deventer | 812 | 1998 |
| 8 | [TenCate](https://www.tamtam.ai/c/tencate) (us.tencatefabrics.com)<br>Design, develop, and produce advanced protective fabrics for professionals in firefighting, military, industry, and energy sectors ensuring safety and comfort. | Textile Manufacturing | 🇳🇱 Nijverdal | 755 |  |
| 9 | [TKF](https://www.tamtam.ai/c/tkf) (tkf.nl)<br>A leading supplier of connectivity solutions providing safe and reliable power and data connections worldwide with specialized knowledge, reliability, and service | Manufacturing | 🇳🇱 Haaksbergen | 663 | 1930 |
| 10 | [Voortman Steel Group](https://www.tamtam.ai/c/voortman-steel-group) (careers.voortman.net)<br>A global steel group focused on modern steel processing machines, innovative software, and services, driven by technology and entrepreneurship | Machinery Manufacturing | 🇳🇱 Rijssen | 597 | 1968 |
| 11 | [PM](https://www.tamtam.ai/c/pm-dedemsvaart) (pm.nl)<br>A family-run company specializes in designing precision linear and rotating bearings, advanced positioning systems, and custom solutions for industries like semiconductor and medical science | Industrial Machinery Manufacturing | 🇳🇱 Dedemsvaart | 530 | 1966 |
| 12 | [Demcon](https://www.tamtam.ai/c/demcon) (demcon.com)<br>Develops, prototypes, industrializes, and manufactures high-quality, innovative, and complex systems and products, integrating various engineering fields to solve societal and technological challenges. | Engineering Services | 🇳🇱 Enschede | 487 | 1993 |
| 13 | [Voortman Steel Machinery](https://www.tamtam.ai/c/voortman-steel-machinery) (voortman.net)<br>Design and manufacture CNC steel processing machinery with integrated software solutions, providing automation, optimization, and comprehensive customer support worldwide. | Machinery Manufacturing | 🇳🇱 Rijssen | 487 | 1968 |
| 14 | [VDL Enabling Technologies Group (ETG) Almelo](https://www.tamtam.ai/c/vdl-etg-almelo) (vdletg.com)<br>Develop and produce complex, innovative modules and systems. Focused on further development of computer chips, combating diseases, and researching the universe for international clients. | Industrial Machinery Manufacturing | 🇳🇱 Almelo | 468 |  |
| 15 | [Bizzdesign](https://www.tamtam.ai/c/bizzdesign) (bizzdesign.com)<br>This company offers enterprise architecture software to improve success rates of enterprise transformation, investment allocation, and risk management for organizations | Software Development | 🇳🇱 Enschede | 440 | 2000 |
| 16 | [Royal GD](https://www.tamtam.ai/c/royal-gd) (gddiergezondheid.nl)<br>The company focuses on improving animal health and safety of animal products through veterinary specialists' guidance on disease prevention, animal husbandry, and welfare | Veterinary Services | 🇳🇱 Deventer | 436 | 1919 |
| 17 | [Roessingh, Centrum voor Revalidatie](https://www.tamtam.ai/c/roessingh-centrum-voor-revalidatie) (roessingh.nl)<br>Specializing in rehabilitation treatment and care for adults and children with various diagnoses, including stroke, pain, and high spinal cord injuries | Hospitals and Health Care | 🇳🇱 Enschede | 407 | 1948 |
| 18 | [Faculty of Geo-Information Science and Earth Observation (ITC) of the University of Twente](https://www.tamtam.ai/c/faculty-of-geo-information-science-and-earth-observation-itc-of-the-university) (utwente.nl)<br>A leading international knowledge hub in geospatial sciences, specializing in collaborative education and research for solving global challenges with spatial information | Higher Education | 🇳🇱 Enschede | 387 | 1950 |
| 19 | [HITEC Power Protection](https://www.tamtam.ai/c/hitec-power-protection) (hitec-ups.com)<br>Manufacturing turnkey power solutions with dynamic UPS systems using flywheel energy storage, ensuring continuous, conditioned power supply to mission critical processes worldwide | Industrial Machinery Manufacturing | 🇳🇱 Almelo | 386 | 1894 |
| 20 | [Koninklijke Euroma BV](https://www.tamtam.ai/c/koninklijke-euroma-bv) (euroma.com)<br>A leading European provider of spice-based solutions for the food industry, specializing in developing tasty, healthy, sustainable, and safe ingredients | Food and Beverage Manufacturing | 🇳🇱 Zwolle | 357 | 1899 |
| 21 | [Indes](https://www.tamtam.ai/c/indes) (indes.eu)<br>Creating successful innovations in Medical Cure, Human Care, and E-mobility by delivering integrated product solutions that improve everyday life | Medical Equipment Manufacturing | 🇳🇱 Enschede | 317 | 1988 |
| 22 | [AHV International](https://www.tamtam.ai/c/ahv-international) (ahvint.com)<br>Innovative provider of animal health solutions, supporting livestock farmers and veterinarians with natural, scientific animal feeds and expert services for better care results | Biotechnology Research | 🇳🇱 Zwolle | 299 | 2014 |
| 23 | [Brink Group](https://www.tamtam.ai/c/brink-group) (brink.eu)<br>Designs and manufactures high-quality towbars for various vehicles, enabling safe and easy towing worldwide with extensive experience. | Motor Vehicle Manufacturing | 🇳🇱 Staphorst | 252 | 1903 |
| 24 | [HoSt Group](https://www.tamtam.ai/c/host-group) (host.nl)<br>A fast-growing family company leading the way in renewable energy generation, specializing in clean conversion technology for sustainable energy solutions globally | Renewable Energy Equipment Manufacturing | 🇳🇱 Enschede | 240 | 1991 |
| 25 | [Bosch Thermotechniek Deventer](https://www.tamtam.ai/c/bosch-thermotechniek-deventer) (nefit-bosch.nl)<br>In Deventer, part of an international group, Bosch Thermotechniek is a leading provider of heating technology, with expertise in research, production, and sales | Industrial Machinery Manufacturing | 🇳🇱 Deventer | 219 | 1948 |
| 26 | [Aeronamic](https://www.tamtam.ai/c/aeronamic) (aeronamic.com)<br>Aeronamic is a leading aerospace company specializing in design, manufacturing, testing, and maintenance of advanced turbomachinery, engine systems, and critical components for aviation | Airlines and Aviation | 🇳🇱 Almelo | 214 | 1988 |
| 27 | [Agrifac Machinery B.V.](https://www.tamtam.ai/c/agrifac-machinery-b-v) (agrifac.com)<br>Design and manufacture of self-propelled sprayers focusing on economics, ecology, efficiency, and ergonomics for sustainable farming. | Machinery Manufacturing | 🇳🇱 Steenwijk | 213 |  |
| 28 | [Rollecate](https://www.tamtam.ai/c/rollecate) (rollecate.nl)<br>A leading provider of custom aluminum and steel windows, doors, and complex facade systems for residential and commercial buildings since 1954 | Wholesale Building Materials | 🇳🇱 Staphorst | 212 | 1954 |
| 29 | [Beaphar B.V.](https://www.tamtam.ai/c/beaphar-b-v) (beaphar.com)<br>Develops manufactures pharmaceuticals, healthcare products, and super premium complete foods for all types of pets, improving their lives for over 80 years. | Pharmaceutical Manufacturing | 🇳🇱 Raalte | 177 | 1943 |
| 30 | [SELO](https://www.tamtam.ai/c/selo) (selo.com)<br>Provider of food and animal feed processing equipment and systems, offering stand-alone machines, turnkey production lines, tailor-made installations, and after-sales support | Machinery Manufacturing | 🇳🇱 Hengelo | 148 | 1944 |
| 31 | [DGS Processing Solutions](https://www.tamtam.ai/c/dgs-processing-solutions) (dgs-ps.com)<br>Designs, manufactures, installs, and maintains highly automated systems and lines for primary meat processing and product handling, including robotics. | Industrial Machinery Manufacturing | 🇳🇱 Haaksbergen | 108 | 2014 |
| 32 | [TKH Group](https://www.tamtam.ai/c/tkh-group) (tkhgroup.com)<br>A leading technology company focusing on innovative systems in Smart Vision, Manufacturing, and Connectivity, aiming to improve efficiency, sustainability, safety, and security globally | Automation Machinery Manufacturing | 🇳🇱 Haaksbergen | 103 |  |
| 33 | [Alltech Coppens](https://www.tamtam.ai/c/alltech-coppens) (alltechcoppens.com)<br>Provides aquaculture feed solutions for all farmed fish stages, focusing on nutrition, health, and sustainable feed production technology, maximizing farm performance. | Food and Beverage Manufacturing | 🇳🇱 Helmond | 92 | 1993 |
| 34 | [QuiX Quantum](https://www.tamtam.ai/c/quix-quantum) (quixquantum.com)<br>Building photonic quantum computers designed for scalability, data-center readiness, and the path toward fault-tolerant quantum computing through integrated photonics and quantum optics. | Computer Hardware Manufacturing | 🇳🇱 Enschede | 72 | 2019 |
| 35 | [De Dessert Meesters](https://www.tamtam.ai/c/de-dessert-meesters) (linktr.ee)<br>A Dutch company creates unique ice cream desserts with high-quality ingredients and innovative flavors, available in 26 European countries | Food and Beverage Manufacturing | 🇳🇱 Oldenzaal | 42 | 1925 |
| 36 | [OneThird](https://www.tamtam.ai/c/onethird) (onethird.io)<br>The company utilizes optical sensors and AI to predict produce spoilage, helping retailers reduce food waste and improve inventory management | IT Services and IT Consulting | 🇳🇱 Enschede | 33 | 2019 |
| 37 | [Datacadabra BV](https://www.tamtam.ai/c/datacadabra-bv) (datacadabra.nl)<br>Develops data science and artificial intelligence for practical applications, saving time and costs through smart, scalable solutions for various organizations. | IT Services and IT Consulting | 🇳🇱 Enschede | 17 | 2015 |
| 38 | [Davines Group - Netherlands \| Certified B Corp](https://www.tamtam.ai/c/davines-group-netherlands-certified-b-corp) (davinesgroup.com)<br>A family-owned group producing high-end hair and skin care products, promoting a holistic, sustainable lifestyle with a focus on beauty, ethics, and sustainability globally | Personal Care Product Manufacturing | 🇳🇱 Deventer | 13 |  |
| 39 | [Hitec Food Systems B.V.](https://www.tamtam.ai/c/hitec-food-systems-b-v) (hitecbv.nl)<br>A company with 35 years of experience specializing in developing and producing stainless steel process solutions for the food industry | Food and Beverage Manufacturing | 🇳🇱 Zwolle | 12 | 2005 |
| 40 | [Spectro-AI](https://www.tamtam.ai/c/spectro-ai) (spectroai.ai)<br>Designs and develops AI solutions, software and hardware, for detecting and analyzing objects and areas from sky (drone) and space (satellite). | Software Development | 🇳🇱 Enschede | 8 | 2018 |
| 41 | [Intelligent Data & Internet Of Things](https://www.tamtam.ai/c/intelligent-data-and-internet-of-things) (theidiotcompany.eu)<br>The company provides intelligent data and secure sensor solutions to businesses, aiming to bring control and insight while reducing environmental impact | IT Services and IT Consulting | 🇳🇱 Enschede | 2 | 2016 |

## How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 11, 2026.

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Source: https://www.tamtam.ai/l/r-and-d-companies-overijssel