# 100 leading companies with in-house R&D in Pennsylvania

Tamtam tracks 255 companies with in-house R&D headquartered in Pennsylvania. This list ranks the 100 largest by number of employees on LinkedIn, led by Comcast, UPMC and PPG. Their median headcount is 3,489. Half of them were founded in 1946 or later. The most common headquarters are Pittsburgh (21), Philadelphia (18) and Allentown (5).

These large organizations in Pennsylvania engage in in-house research and development across diverse sectors. Comcast delivers broadband and entertainment, UPMC provides healthcare and insurance, PPG develops paints and coatings, and Penn State University offers interdisciplinary education. Other notable companies include Wabtec Corporation, which supplies rail equipment, and Air Products, a global supplier of industrial gases.

The data reveals a strong concentration of R&D activities in the state's major cities. A significant number of these large companies are either headquartered in Philadelphia or Pittsburgh, with several prominent universities and healthcare systems also located in these urban centers. The presence of both long-established companies, like PPG (founded 1883), and more recent ventures, highlights a varied historical footprint.

🇺🇸 Pennsylvania · 100 companies · Updated Nov 11, 2026

| # | Company | Industry | Headquarters | Employees | Founded |
|---|---|---|---|---|---|
| 1 | [Comcast](https://www.tamtam.ai/c/comcast) (comcast.com)<br>Delivering broadband, mobile, and video products, along with entertainment, sports, news, and theme park experiences; driven by passionate creators and innovators | Telecommunications | 🇺🇸 Philadelphia | 189,000 | 1963 |
| 2 | [UPMC](https://www.tamtam.ai/c/upmc) (upmc.com)<br>A leading health care provider and insurer in Pittsburgh, offering patient-centered care, innovative models, and community benefits through hospitals and insurance services | Hospitals and Health Care | 🇺🇸 Pittsburgh | 41,860 |  |
| 3 | [PPG](https://www.tamtam.ai/c/ppg) (ppg.com)<br>Development and delivery of paints, coatings, and specialty materials serving construction, consumer products, industrial, transportation, and aftermarket markets worldwide. | Paint, Coating, and Adhesive Manufacturing | 🇺🇸 Pittsburgh | 33,277 | 1883 |
| 4 | [Penn State University](https://www.tamtam.ai/c/penn-state-university) (psu.edu)<br>Providing interdisciplinary education and resources across multiple campuses, fostering student success and positive global community impact through knowledge and experience. | Higher Education | 🇺🇸 University Park | 31,986 | 1855 |
| 5 | [Wabtec Corporation](https://www.tamtam.ai/c/wabtec-corporation) (wabteccorp.com)<br>Provider of equipment, systems, digital solutions, and services for freight rail, transit, mining, industrial, and marine transportation sectors. | Railroad Equipment Manufacturing | 🇺🇸 Pittsburgh | 27,000 | 1869 |
| 6 | [University of Pennsylvania](https://www.tamtam.ai/c/university-of-pennsylvania) (upenn.edu)<br>Renowned Ivy League university with 12 schools offering a wide range of programs including arts, sciences, engineering, business, and medicine | Higher Education | 🇺🇸 Philadelphia | 22,558 | 1740 |
| 7 | [Penn Medicine, University of Pennsylvania Health System](https://www.tamtam.ai/c/penn-medicine-university-of-pennsylvania-health-system) (pennmedicine.org)<br>Leading academic medical center combining cutting-edge research, comprehensive patient care, and education to improve health and transform lives regionally. | Hospitals and Health Care | 🇺🇸 Philadelphia | 21,979 |  |
| 8 | [Air Products](https://www.tamtam.ai/c/air-products) (airproducts.com)<br>Supplier of industrial gases serving over 250,000 customers in more than 50 countries worldwide with diverse applications. | Chemical Manufacturing | 🇺🇸 Allentown | 20,000 | 1940 |
| 9 | [University of Pittsburgh](https://www.tamtam.ai/c/university-of-pittsburgh) (pitt.edu)<br>Top-ranked public institution in Pennsylvania, member of leading research universities Known for innovative discoveries and shaping future paths | Higher Education | 🇺🇸 Pittsburgh | 19,349 | 1787 |
| 10 | [Children's Hospital of Philadelphia](https://www.tamtam.ai/c/children-s-hospital-of-philadelphia) (chop.edu)<br>Specialized pediatric hospital providing exceptional patient care, pioneering medical research, and training future pediatric healthcare professionals. | Hospitals and Health Care | 🇺🇸 Philadelphia | 18,042 | 1855 |
| 11 | [Viatris](https://www.tamtam.ai/c/viatris) (viatris.com)<br>Global healthcare company providing extensive medicine portfolio and supply chain to deliver high-quality medicines addressing diverse health needs worldwide. | Pharmaceutical Manufacturing | 🇺🇸 Pittsburgh | 17,886 |  |
| 12 | [Geisinger](https://www.tamtam.ai/c/geisinger) (geisinger.org)<br>Healthcare organization with 13 hospital campuses, research centers, medical college, and health plan serving millions in Pennsylvania Committed to quality healthcare | Hospitals and Health Care | 🇺🇸 Danville | 15,962 | 1915 |
| 13 | [Mylan](https://www.tamtam.ai/c/mylan) (viatris.com)<br>Empowering people worldwide to live healthier at every stage of life through a merger with Upjohn, now known as Viatris | Pharmaceutical Manufacturing | 🇺🇸 Canonsburg | 15,198 |  |
| 14 | [Temple University](https://www.tamtam.ai/c/temple-university) (temple.edu)<br>A top-tier research institution in a vibrant city, offering diverse degree programs to prepare future leaders for impactful careers | Higher Education | 🇺🇸 Philadelphia | 13,124 | 1884 |
| 15 | [FMC Corporation](https://www.tamtam.ai/c/fmc-corporation) (fmc.com)<br>The company is dedicated to innovating sustainable technologies to protect crops, support farmers, and tackle agriculture's challenges using science | Agricultural Chemical Manufacturing | 🇺🇸 Philadelphia | 11,986 | 1883 |
| 16 | [Allegheny Health Network](https://www.tamtam.ai/c/allegheny-health-network) (ahn.org)<br>Integrated healthcare delivery system with hospitals, medical centers, wellness pavilions, and numerous physician practices serving Western Pennsylvania. | Hospitals and Health Care | 🇺🇸 Pittsburgh | 11,676 |  |
| 17 | [The Hershey Company](https://www.tamtam.ai/c/the-hershey-company) (thehersheycompany.com)<br>Leading global snacks company producing iconic confectionery brands, committed to quality products, community support, and educational initiatives. | Manufacturing | 🇺🇸 Hershey | 11,057 | 1894 |
| 18 | [Teleflex](https://www.tamtam.ai/c/teleflex) (teleflex.com)<br>Provides diverse medical technologies and solutions across various therapy areas, improving health and quality of life for people worldwide through purpose-driven innovation. | Medical Equipment Manufacturing | 🇺🇸 Wayne | 9,909 | 1943 |
| 19 | [Penn State Health](https://www.tamtam.ai/c/penn-state-health) (pennstatehealth.org)<br>Multi-hospital health system in central Pennsylvania with medical centers, outpatient practices, and a partnership with Highmark Health for community care | Hospitals and Health Care | 🇺🇸 Hershey | 8,037 | 1963 |
| 20 | [Axalta](https://www.tamtam.ai/c/axalta) (axalta.com)<br>A global provider of performance coatings for industrial, automotive, and refinish applications, focused on innovation for a sustainable future | Chemical Manufacturing | 🇺🇸 Philadelphia | 7,744 | 2013 |
| 21 | [B. Braun Medical Inc. (US)](https://www.tamtam.ai/c/b-braun-medical-inc-us) (bbraunusa.com)<br>A global healthcare leader specializing in infusion therapy, pain management, nutrition, pharmacy admixture, and dialysis products and services Committed to safety and innovation | Medical Equipment Manufacturing | 🇺🇸 Bethlehem | 7,619 | 1839 |
| 22 | [Drexel University](https://www.tamtam.ai/c/drexel-university) (drexel.edu)<br>Academically comprehensive urban research university with a globally engaged community and a premier cooperative education program nationwide. | Higher Education | 🇺🇸 Philadelphia | 7,580 | 1891 |
| 23 | [Howmet Aerospace](https://www.tamtam.ai/c/howmet-aerospace) (howmet.com)<br>A global provider of advanced engineered solutions for aerospace and transportation industries, specializing in jet engine components, aerospace fastening systems, and titanium structural parts | Aviation and Aerospace Component Manufacturing | 🇺🇸 Pittsburgh | 7,402 | 2020 |
| 24 | [Coherent Corp.](https://www.tamtam.ai/c/coherent-corp) (coherent.com)<br>Development and delivery of breakthrough technologies and innovations for industrial, communications, electronics, and instrumentation market applications worldwide. | Semiconductor Manufacturing | 🇺🇸 Saxonburg | 7,389 | 1971 |
| 25 | [Clario](https://www.tamtam.ai/c/clario-philadelphia) (clario.com)<br>A leading healthcare research and technology company providing expertise and technology for advancing clinical trials in various therapeutic areas worldwide | Biotechnology Research | 🇺🇸 Philadelphia | 7,151 | 1972 |
| 26 | [PPL Corporation](https://www.tamtam.ai/c/ppl-corporation) (pplweb.com)<br>Providing electricity to millions, building smarter, resilient power grids, advancing sustainable energy solutions, and fostering inclusive work environments. | Utilities | 🇺🇸 Allentown | 7,118 | 1920 |
| 27 | [United States Steel Corporation](https://www.tamtam.ai/c/united-states-steel-corporation) (ussteel.com)<br>Developing and delivering profitable, next-generation steel solutions focused on safety and meeting current and future customer needs. | Manufacturing | 🇺🇸 Pittsburgh | 6,794 | 1901 |
| 28 | [Kennametal](https://www.tamtam.ai/c/kennametal) (kennametal.com)<br>A global industrial technology leader specializing in advanced materials innovation, tooling, and wear-resistant solutions to enhance productivity for various industries | Machinery Manufacturing | 🇺🇸 Pittsburgh | 6,659 |  |
| 29 | [Ansys](https://www.tamtam.ai/c/ansys) (ansys.com)<br>Delivering silicon design breakthroughs and IP to enable rapid innovation of AI-powered products across multiple high-tech industries. | Software Development | 🇺🇸 Canonsburg | 6,283 | 1970 |
| 30 | [West Pharmaceutical Services](https://www.tamtam.ai/c/west-pharmaceutical-services) (westpharma.com)<br>provider of high-quality injectable components and devices ensuring safe, effective delivery and containment of medicines worldwide | Pharmaceutical Manufacturing | 🇺🇸 Exton | 6,268 | 1923 |
| 31 | [EnerSys](https://www.tamtam.ai/c/enersys) (enersys.com)<br>Global leader in stored energy solutions for industrial applications, offering motive power, reserve power, aerospace/defense, specialty batteries, and integrated services worldwide | Appliances, Electrical, and Electronics Manufacturing | 🇺🇸 Reading | 6,257 |  |
| 32 | [AMETEK](https://www.tamtam.ai/c/ametek) (ametek.com)<br>Global provider of industrial technology solutions with over $60 billion in annual sales, serving niche markets with differentiated technology solutions and focused on shareholder value generation | Manufacturing | 🇺🇸 Berwyn | 5,963 | 1930 |
| 33 | [Crown Holdings, Inc.](https://www.tamtam.ai/c/crown-holdings-inc) (crowncork.com)<br>Design manufacture and sale of steel and aluminum cans, glass bottles, closures, and industrial packaging products and equipment worldwide. | Packaging and Containers Manufacturing | 🇺🇸 Yardley | 5,891 | 1892 |
| 34 | [Temple Health – Temple University Health System](https://www.tamtam.ai/c/temple-health-temple-university-health-system) (templehealth.org)<br>Temple Health provides advanced research and clinical care, offering innovative treatments through renowned physicians, nurses, and researchers in various medical facilities and practices | Hospitals and Health Care | 🇺🇸 Philadelphia | 5,770 | 1892 |
| 35 | [Thomas Jefferson University](https://www.tamtam.ai/c/thomas-jefferson-university) (jefferson.edu)<br>University focused on innovative health education, interdisciplinary learning, expert faculty collaboration, and redefining possibilities in health, education, and discovery. | Higher Education | 🇺🇸 Philadelphia | 5,700 | 1824 |
| 36 | [Bentley Systems](https://www.tamtam.ai/c/bentley-systems) (bentley.com)<br>Innovative software for infrastructure engineering, design, construction, and operations, advancing global economy and environment with industry-leading solutions in multiple sectors worldwide | Software Development | 🇺🇸 Exton | 5,633 | 1984 |
| 37 | [Vishay Intertechnology, Inc.](https://www.tamtam.ai/c/vishay-intertechnology-inc) (vishay.com)<br>Manufactures extensive range of discrete semiconductors and passive electronic components for automotive, industrial, computing, consumer, telecom, military, aerospace, and medical markets worldwide. | Appliances, Electrical, and Electronics Manufacturing | 🇺🇸 Malvern | 5,426 |  |
| 38 | [PCI Pharma Services](https://www.tamtam.ai/c/pci-pharma-services) (pci.com)<br>Provides world-class solutions for drug development, manufacturing, advanced drug delivery, clinical trials, and commercial packaging, delivering life-changing therapies globally. | Pharmaceutical Manufacturing | 🇺🇸 Philadelphia | 4,795 |  |
| 39 | [Olympus Corporation of the Americas](https://www.tamtam.ai/c/olympus-corporation-of-the-americas) (olympusamerica.com)<br>A global medical technology company partnering with healthcare professionals to provide solutions for early detection, diagnosis, and minimally invasive treatment | Medical Equipment Manufacturing | 🇺🇸 Center Valley | 4,752 |  |
| 40 | [Arconic](https://www.tamtam.ai/c/arconic) (arconic.com)<br>A leading provider of aluminum products for automotive, aerospace, transportation, industrial, packaging, and construction markets, committed to innovation and advancement | Manufacturing | 🇺🇸 Pittsburgh | 4,672 | 2016 |
| 41 | [Qlik](https://www.tamtam.ai/c/qlik) (qlik.com)<br>Delivers trusted data products, powerful analytics engines, and AI agents helping teams scale responsibly while reducing risk and maintaining flexible system integration. | Software Development | 🇺🇸 King of Prussia | 4,561 | 1993 |
| 42 | [MSA - The Safety Company](https://www.tamtam.ai/c/msa-the-safety-company) (msasafety.com)<br>Designs and manufactures advanced safety products and technologies protecting workers and infrastructure worldwide across diverse industries. | Public Safety | 🇺🇸 Cranberry Township | 4,260 | 1914 |
| 43 | [Naval Nuclear Laboratory (FMP)](https://www.tamtam.ai/c/naval-nuclear-laboratory-fmp) (navalnuclearlab.energy.gov)<br>The company operates the Naval Nuclear Laboratory, supporting the US Naval Nuclear Propulsion Program through research, development, training, and technical support | Defense and Space Manufacturing | 🇺🇸 West Mifflin | 3,940 | 1946 |
| 44 | [TRIUMPH](https://www.tamtam.ai/c/triumph-radnor) (triumphgroup.com)<br>Design, engineering, manufacturing, repair, and overhaul of aviation and industrial components, partnering with OEMs and operators globally. | Aviation and Aerospace Component Manufacturing | 🇺🇸 Radnor | 3,933 | 1993 |
| 45 | [Susquehanna International Group](https://www.tamtam.ai/c/susquehanna-international-group) (sig.com)<br>global proprietary trading firm providing liquidity, competitive pricing, quantitative strategies, private equity, structured capital, and institutional brokerage services | Financial Services | 🇺🇸 Bala Cynwyd | 3,913 | 1987 |
| 46 | [Graham Packaging](https://www.tamtam.ai/c/graham-packaging) (grahampackaging.com)<br>A leader in sustainable packaging design, manufacturing, and sales for food, beverage, household, and automotive industries with global reach | Packaging and Containers Manufacturing | 🇺🇸 Lancaster | 3,562 | 1970 |
| 47 | [Quaker Houghton](https://www.tamtam.ai/c/quaker-houghton) (home.quakerhoughton.com)<br>Global leader in industrial process fluids, serving advanced manufacturing industries with expertise in chemistry and engineering for efficient operations and future growth | Chemical Manufacturing | 🇺🇸 Conshohocken | 3,523 |  |
| 48 | [CertainTeed](https://www.tamtam.ai/c/certainteed) (certainteed.com)<br>A leading provider of sustainable exterior and interior building products in North America, with a focus on innovation and environmental responsibility | Wholesale Building Materials | 🇺🇸 Malvern | 3,511 | 1904 |
| 49 | [Crane Payment Innovations](https://www.tamtam.ai/c/crane-payment-innovations) (cranepi.com)<br>Provides world-class, automated payment solutions and experiences, developing products in currency validation, cash management, digital payment, mobile apps, and security for global consumers. | Appliances, Electrical, and Electronics Manufacturing | 🇺🇸 Malvern | 3,504 |  |
| 50 | [UPMC Children's Hospital of Pittsburgh](https://www.tamtam.ai/c/upmc-children-s-hospital-of-pittsburgh) (chp.edu)<br>A leader in treating childhood conditions, developing therapies, educating pediatricians, and advancing research with strong community support since 1890 | Hospitals and Health Care | 🇺🇸 Pittsburgh | 3,489 | 1890 |
| 51 | [Globus Medical](https://www.tamtam.ai/c/globus-medical) (globusmedical.com)<br>Development and manufacturing of innovative orthopedic surgical products focused on improving patient outcomes and enabling pain-free, active lives. | Medical Equipment Manufacturing | 🇺🇸 Audubon | 3,451 | 2003 |
| 52 | [Eurofins Lancaster Laboratories](https://www.tamtam.ai/c/eurofins-lancaster-laboratories) (eurofinsus.com)<br>A global contract laboratory providing comprehensive services in pharmaceutical, biopharmaceutical, and environmental sciences to a diverse range of clients worldwide | Biotechnology Research | 🇺🇸 Lancaster | 3,426 | 1961 |
| 53 | [Victaulic](https://www.tamtam.ai/c/victaulic) (victaulic.com)<br>A global leader in pipe joining and flow control solutions for construction projects, offering innovative products and technologies for increased system durability | Industrial Machinery Manufacturing | 🇺🇸 Easton | 3,373 | 1919 |
| 54 | [SunGard - now part of FIS](https://www.tamtam.ai/c/sungard-now-part-of-fis) (fisglobal.com)<br>Financial technology company offering updates and news through LinkedIn and FISGlobalcom after acquiring SunGard | IT Services and IT Consulting | 🇺🇸 Wayne | 3,348 | 1968 |
| 55 | [Lutron Electronics](https://www.tamtam.ai/c/lutron-electronics) (lutron.com)<br>Design and manufacture innovative lighting, shading, and control systems to enhance everyday experiences through transformative light technology. | Appliances, Electrical, and Electronics Manufacturing | 🇺🇸 Coopersburg | 3,347 | 1961 |
| 56 | [Boeing Defense, Space & Security](https://www.tamtam.ai/c/boeing-defense-space-and-security) (boeing.com)<br>A division of a leading company focusing on defense and aerospace products and services, based in Arlington, Virginia Formerly known as Boeing Integrated Defense Systems | Business Consulting and Services | 🇺🇸 Wayne | 3,334 | 2002 |
| 57 | [Carpenter Technology Corporation](https://www.tamtam.ai/c/carpenter-technology-corporation) (carpentertechnology.com)<br>Producer and distributor of premium specialty alloys and advanced materials for aerospace, transportation, medical, energy, and additive manufacturing applications. | Manufacturing | 🇺🇸 Philadelphia | 3,271 | 1889 |
| 58 | [Armstrong World Industries](https://www.tamtam.ai/c/armstrong-world-industries) (armstrongceilings.com)<br>Design and manufacture innovative ceiling and wall systems enhancing aesthetics, acoustics, well-being, and sustainability in various interior spaces. | Wholesale Building Materials | 🇺🇸 Lancaster | 3,186 | 1860 |
| 59 | [Excelitas Technologies Corp.](https://www.tamtam.ai/c/excelitas-technologies-corp) (excelitas.com)<br>Provider of advanced photonic technologies specializing in sensing, detection, imaging, optics, and specialty illumination for diverse global industries. | Manufacturing | 🇺🇸 Pittsburgh | 3,129 |  |
| 60 | [JLG Industries](https://www.tamtam.ai/c/jlg-industries) (jlg.com)<br>Manufacturing mobile elevating work platforms, telehandlers, utility vehicles, and accessories for construction and industrial safety worldwide. | Machinery Manufacturing | 🇺🇸 McConnellsburg | 3,052 | 1969 |
| 61 | [Boomi](https://www.tamtam.ai/c/boomi) (boomi.com)<br>The company offers a platform for intelligent connectivity and automation, enabling seamless connections between people and devices regardless of location | Software Development | 🇺🇸 Conshohocken | 3,030 | 2000 |
| 62 | [Aurora](https://www.tamtam.ai/c/aurora-pittsburgh) (aurora.tech)<br>Aurora provides self-driving technology for transportation, making it safer, more accessible, and efficient for various vehicle types and industries | Software Development | 🇺🇸 Pittsburgh | 2,568 | 2017 |
| 63 | [Matthews International](https://www.tamtam.ai/c/matthews-international) (matw.com)<br>Global provider of precision industrial technologies and memorialization products, serving industries and funeral homes with innovative, efficient solutions. | Manufacturing | 🇺🇸 Pittsburgh | 2,226 | 1850 |
| 64 | [Dorman Products](https://www.tamtam.ai/c/dorman-products) (dormanproducts.com)<br>Manufacture and supply aftermarket automotive, heavy-duty, and specialty vehicle replacement parts designed to save time, money, and increase reliability. | Motor Vehicle Parts Manufacturing | 🇺🇸 Colmar | 2,210 | 1918 |
| 65 | [University of Pittsburgh School of Medicine](https://www.tamtam.ai/c/university-of-pittsburgh-school-of-medicine) (medschool.pitt.edu)<br>Training physician leaders and scientists to improve health, advance research, promote equity, and collaborate internationally in medicine and education. | Higher Education | 🇺🇸 Pittsburgh | 2,199 | 1886 |
| 66 | [Fox Chase Cancer Center](https://www.tamtam.ai/c/fox-chase-cancer-center) (foxchase.org)<br>Dedicated cancer hospital with expert multidisciplinary teams advancing prevention, diagnosis, treatment, and survivorship through pioneering research and clinical care. | Hospitals and Health Care | 🇺🇸 Philadelphia | 2,146 | 1904 |
| 67 | [DDI \| Development Dimensions International](https://www.tamtam.ai/c/ddi-development-dimensions-international) (ddiworld.com)<br>Global leadership consulting firm assisting organizations with hiring, promotion, and development of exceptional leaders from first-time managers to senior C-suite executive levels. | Human Resources Services | 🇺🇸 Bridgeville | 2,120 | 1970 |
| 68 | [Trinseo](https://www.tamtam.ai/c/trinseo) (trinseo.com)<br>A specialty material solutions provider partnering with companies to innovate and create sustainable products across various industries worldwide | Chemical Manufacturing | 🇺🇸 Wayne | 2,009 |  |
| 69 | [Drexel University College of Medicine](https://www.tamtam.ai/c/drexel-university-college-of-medicine) (drexel.edu)<br>A prestigious medical school offering MD and graduate programs, committed to diversity and excellence in medical education and research | Higher Education | 🇺🇸 Philadelphia | 1,935 | 2002 |
| 70 | [Industrial Coatings](https://www.tamtam.ai/c/industrial-coatings) (ppg.com)<br>Global provider of advanced coatings, paints, and specialty materials focused on protecting and enhancing industrial products and landmarks. | Wholesale Building Materials | 🇺🇸 Pittsburgh | 1,830 |  |
| 71 | [Southco, Inc.](https://www.tamtam.ai/c/southco-inc) (southco.com)<br>Global leader in engineered access solutions for transportation, industrial, medical, and data center applications, with innovative products and a dedicated global team serving customers worldwide | Industrial Machinery Manufacturing | 🇺🇸 Concordville | 1,720 | 1899 |
| 72 | [Crayola](https://www.tamtam.ai/c/crayola) (crayola.com)<br>A leading art product company inspiring creativity in children globally, promoting diversity, inclusion, and sustainability in its operations and products | Manufacturing | 🇺🇸 Easton | 1,687 | 1903 |
| 73 | [Ebara Elliott Energy](https://www.tamtam.ai/c/ebara-elliott-energy) (elliott-turbo.com)<br>Designs and manufactures centrifugal compressors, steam turbines, pumps, and cryogenic products for petrochemical, refining, oil and gas industries. | Industrial Machinery Manufacturing | 🇺🇸 Jeannette | 1,644 | 1910 |
| 74 | [Certara](https://www.tamtam.ai/c/certara) (certara.com)<br>This company accelerates medicine development by using biosimulation software, technology, and services to revolutionize drug discovery and development globally | Business Consulting and Services | 🇺🇸 Radnor | 1,514 |  |
| 75 | [Sharp Services](https://www.tamtam.ai/c/sharp-services) (sharpservices.com)<br>Provides commercial packaging, clinical services, and sterile manufacturing for pharmaceutical and biotech clients, covering R&D to market launch globally. | Pharmaceutical Manufacturing | 🇺🇸 Allentown | 1,506 | 1993 |
| 76 | [TestingXperts](https://www.tamtam.ai/c/testingxperts) (testingxperts.com)<br>A global leader in Quality Engineering and Digital Assurance services, offering a comprehensive range of testing solutions for Next Gen technologies | IT Services and IT Consulting | 🇺🇸 Mechanicsburg | 1,480 | 2013 |
| 77 | [SK pharmteco](https://www.tamtam.ai/c/sk-pharmteco) (skpharmteco.com)<br>Global contract development and manufacturing organization for active pharmaceutical ingredients, advanced intermediates, and cell and gene therapy for the pharmaceutical industry. | Pharmaceutical Manufacturing | 🇺🇸 Rancho Cordova | 1,433 |  |
| 78 | [FXI](https://www.tamtam.ai/c/fxi) (fxi.com)<br>A leading producer of innovation for various markets, creating products for home, healthcare, electronics, personal care, transportation, and industrial applications | Manufacturing | 🇺🇸 Radnor | 1,408 |  |
| 79 | [Vishay Precision Group, Inc. (VPG)](https://www.tamtam.ai/c/vishay-precision-group-inc-vpg) (vpgsensors.com)<br>A global leader in precision measurement sensing technologies, focusing on accuracy, reliability, and repeatability for various applications worldwide | Appliances, Electrical, and Electronics Manufacturing | 🇺🇸 Malvern | 1,334 | 2010 |
| 80 | [Aquatech](https://www.tamtam.ai/c/aquatech) (aquatech.com)<br>Global leader in water technology, specializing in desalination, water reuse, and zero liquid discharge solutions to reduce water and carbon footprint worldwide | Environmental Services | 🇺🇸 Canonsburg | 1,270 | 1981 |
| 81 | [Greene Tweed](https://www.tamtam.ai/c/greene-tweed) (gtweed.com)<br>Global manufacturer of high-performance thermoplastics, composites, seals, and engineered components for industries like semiconductor, oil & gas, aerospace, defense, and pharmaceutical processing | Manufacturing | 🇺🇸 Lansdale | 1,238 | 1863 |
| 82 | [Colorcon](https://www.tamtam.ai/c/colorcon) (colorcon.com)<br>Develops, supplies, and supports formulated film coating systems, modified release technologies, core excipients, and functional packaging for the pharmaceutical industry. | Pharmaceutical Manufacturing | 🇺🇸 Harleysville | 1,228 | 1961 |
| 83 | [Concurrent Technologies Corporation](https://www.tamtam.ai/c/concurrent-technologies-corporation) (ctc.com)<br>Independent nonprofit organization providing applied scientific research, development, testing, prototyping, and innovative solutions supporting national security and American manufacturing. | Defense and Space Manufacturing | 🇺🇸 Johnstown | 1,134 | 1987 |
| 84 | [Madrigal Pharmaceuticals](https://www.tamtam.ai/c/madrigal-pharmaceuticals) (madrigalpharma.com)<br>Clinical-stage biopharmaceutical company developing novel therapeutics for NASH, focusing on thyroid hormone receptor agonist to target underlying causes in the liver | Pharmaceutical Manufacturing | 🇺🇸 Conshohocken | 1,133 | 2016 |
| 85 | [Koppers Inc.](https://www.tamtam.ai/c/koppers-inc) (koppers.com)<br>A global wood preservation technology company creating environmentally responsible solutions for various industries, with a focus on safety and sustainability | Chemical Manufacturing | 🇺🇸 Pittsburgh | 1,080 | 1988 |
| 86 | [Software Engineering Institute \| Carnegie Mellon University](https://www.tamtam.ai/c/software-engineering-institute-carnegie-mellon-university) (sei.cmu.edu)<br>The company conducts research on software engineering, cybersecurity, and AI, creating and testing innovative technologies for government and private industry since 1984 | Software Development | 🇺🇸 Pittsburgh | 1,061 | 1984 |
| 87 | [Tobyhanna Army Depot](https://www.tamtam.ai/c/tobyhanna-army-depot) (tobyhanna.army.mil)<br>Leader in logistics support for military C5ISR systems, offering sustainment, overhaul, manufacturing, engineering, integration, and field support for the Department of Defense | Armed Forces | 🇺🇸 Tobyhanna | 1,046 | 1953 |
| 88 | [Talogy](https://www.tamtam.ai/c/talogy) (talogy.com)<br>Experts in talent management crafting solutions for screening, selecting, developing, and engaging talent worldwide using psychology and technology for data-driven decisions | Human Resources Services | 🇺🇸 Pittsburgh | 1,036 | 1946 |
| 89 | [Spark Therapeutics, Inc.](https://www.tamtam.ai/c/spark-therapeutics-inc) (sparktx.com)<br>Leading gene therapy company focused on treating inherited diseases through innovative science, integrated expertise, and commitment to accelerating healthcare transformation globally | Biotechnology Research | 🇺🇸 Philadelphia | 1,035 | 2013 |
| 90 | [TIMET](https://www.tamtam.ai/c/timet) (timet.com)<br>A leading producer of titanium melted and mill products for various industries worldwide, offering a wide range of high-quality titanium products | Mining | 🇺🇸 Pittsburgh | 1,028 | 1950 |
| 91 | [Temple University - Lewis Katz School of Medicine](https://www.tamtam.ai/c/temple-university-lewis-katz-school-of-medicine) (temple.edu)<br>Leading medical school offering humanistic education, top clinical training, and groundbreaking research, recognized internationally, honored nationally, and essential locally | Higher Education | 🇺🇸 Philadelphia | 1,015 |  |
| 92 | [Good Shepherd Rehabilitation](https://www.tamtam.ai/c/good-shepherd-rehabilitation) (goodshepherdrehab.org)<br>A not-for-profit rehabilitation network offering inpatient, outpatient, and community-based services for patients of all ages and abilities in eastern PA and NJ | Hospitals and Health Care | 🇺🇸 Allentown | 1,004 | 1908 |
| 93 | [EXALTA Group](https://www.tamtam.ai/c/exalta-group) (exalta.com)<br>Global provider of manufacturing and integrated OEM solutions supporting leading MedTech companies in delivering innovative medical devices worldwide. | Medical Equipment Manufacturing | 🇺🇸 Bethlehem | 995 | 2012 |
| 94 | [Lake Erie College of Osteopathic Medicine (LECOM)](https://www.tamtam.ai/c/lake-erie-college-of-osteopathic-medicine-lecom) (lecom.edu)<br>Training future healthcare professionals in osteopathy, pharmacy, dentistry, and podiatry with a focus on innovation, excellence, and affordability | Higher Education | 🇺🇸 Erie | 956 | 1992 |
| 95 | [Clair Global](https://www.tamtam.ai/c/clair-global) (clairglobal.com)<br>A tech company specializing in live production services and integrated permanent solutions for events | Entertainment Providers | 🇺🇸 Lititz | 943 | 1966 |
| 96 | [Federal Reserve Bank of Philadelphia](https://www.tamtam.ai/c/federal-reserve-bank-of-philadelphia) (philadelphiafed.org)<br>Implement monetary policy, supervise banks, provide financial services to institutions and government One of 12 regional Reserve Banks in Federal Reserve System | Financial Services | 🇺🇸 Philadelphia | 852 | 1914 |
| 97 | [PennEngineering®](https://www.tamtam.ai/c/pennengineering) (pemnet.com)<br>A global leader in engineered fastening, installation, and wire protection solutions with in-house technical engineering experts worldwide since 1942 | Machinery Manufacturing | 🇺🇸 Danboro | 840 | 1942 |
| 98 | [HarbisonWalker International](https://www.tamtam.ai/c/harbisonwalker-international) (thinkhwi.com)<br>A global leader in refractory products delivering solutions to industries worldwide with over 150 years of excellence in performance and value | Glass, Ceramics and Concrete Manufacturing | 🇺🇸 Pittsburgh | 809 | 2000 |
| 99 | [Minaris Advanced Therapies](https://www.tamtam.ai/c/minaris-advanced-therapies) (minaris.com)<br>Global cell and gene therapy CDMO and biosafety testing provider with deep experience supporting therapeutic programs from IND through commercial supply. | Pharmaceutical Manufacturing | 🇺🇸 Tokyo | 808 | 2025 |
| 100 | [Fuller](https://www.tamtam.ai/c/fuller) (fuller-technologies.com)<br>Providing pioneering cement technologies, reliable services, and expertise to help producers operate sustainably and improve performance worldwide. | Industrial Machinery Manufacturing | 🇺🇸 Allentown | 786 | 1882 |

## How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 11, 2026.

## More company lists in Pennsylvania

- [The largest companies in Pennsylvania](https://www.tamtam.ai/l/largest-companies-pennsylvania) (3,427)
- [Multinational companies in Pennsylvania](https://www.tamtam.ai/l/multinational-companies-pennsylvania) (472)
- [Education providers in Pennsylvania](https://www.tamtam.ai/l/education-companies-pennsylvania) (373)
- [Manufacturers in Pennsylvania](https://www.tamtam.ai/l/manufacturers-pennsylvania) (364)
- [Financial services firms in Pennsylvania](https://www.tamtam.ai/l/financial-services-firms-pennsylvania) (264)
- [Healthcare providers in Pennsylvania](https://www.tamtam.ai/l/healthcare-providers-pennsylvania) (264)
- [Retail chains in Pennsylvania](https://www.tamtam.ai/l/retail-chains-pennsylvania) (246)
- [Professional services firms in Pennsylvania](https://www.tamtam.ai/l/professional-services-firms-pennsylvania) (245)
- [Hospitals and Health Care companies in Pennsylvania](https://www.tamtam.ai/l/hospitals-and-health-care-companies-pennsylvania) (243)
- [Critical infrastructure operators in Pennsylvania](https://www.tamtam.ai/l/critical-infrastructure-operators-pennsylvania) (225)
- [Hardware manufacturers in Pennsylvania](https://www.tamtam.ai/l/hardware-companies-pennsylvania) (173)
- [Higher Education companies in Pennsylvania](https://www.tamtam.ai/l/higher-education-companies-pennsylvania) (173)
- [IT Services and IT Consulting companies in Pennsylvania](https://www.tamtam.ai/l/it-services-and-it-consulting-companies-pennsylvania) (172)
- [Financial Services companies in Pennsylvania](https://www.tamtam.ai/l/financial-services-companies-pennsylvania) (160)
- [IT services companies in Pennsylvania](https://www.tamtam.ai/l/it-services-companies-pennsylvania) (157)
- [Consulting firms in Pennsylvania](https://www.tamtam.ai/l/consulting-firms-pennsylvania) (144)
- [Companies with a mobile app in Pennsylvania](https://www.tamtam.ai/l/companies-with-mobile-app-pennsylvania) (130)
- [Family-owned companies in Pennsylvania](https://www.tamtam.ai/l/family-owned-companies-pennsylvania) (130)
- [Public sector organisations in Pennsylvania](https://www.tamtam.ai/l/public-sector-organisations-pennsylvania) (123)
- [Corporate groups and holding companies in Pennsylvania](https://www.tamtam.ai/l/holding-companies-pennsylvania) (120)
- [Publicly traded companies in Pennsylvania](https://www.tamtam.ai/l/publicly-traded-companies-pennsylvania) (116)
- [SaaS companies in Pennsylvania](https://www.tamtam.ai/l/saas-companies-pennsylvania) (114)
- [Construction companies in Pennsylvania](https://www.tamtam.ai/l/construction-companies-pennsylvania) (106)
- [Insurance companies in Pennsylvania](https://www.tamtam.ai/l/insurance-companies-pennsylvania) (101)

## The same list elsewhere in United States

- [Companies with in-house R&D in the United States](https://www.tamtam.ai/l/r-and-d-companies-united-states) (6,796)
- [Companies with in-house R&D in California](https://www.tamtam.ai/l/r-and-d-companies-california) (1,276)
- [Companies with in-house R&D in Texas](https://www.tamtam.ai/l/r-and-d-companies-texas) (442)
- [Companies with in-house R&D in New York State](https://www.tamtam.ai/l/r-and-d-companies-new-york-state) (419)
- [Companies with in-house R&D in Massachusetts](https://www.tamtam.ai/l/r-and-d-companies-massachusetts) (396)
- [Companies with in-house R&D in Illinois](https://www.tamtam.ai/l/r-and-d-companies-illinois) (322)
- [Companies with in-house R&D in Michigan](https://www.tamtam.ai/l/r-and-d-companies-michigan) (287)
- [Companies with in-house R&D in Ohio](https://www.tamtam.ai/l/r-and-d-companies-ohio) (277)
- [Companies with in-house R&D in New Jersey](https://www.tamtam.ai/l/r-and-d-companies-new-jersey) (224)
- [Companies with in-house R&D in Florida](https://www.tamtam.ai/l/r-and-d-companies-florida) (221)
- [Companies with in-house R&D in Alabama](https://www.tamtam.ai/l/r-and-d-companies-alabama) (214)
- [Companies with in-house R&D in Georgia](https://www.tamtam.ai/l/r-and-d-companies-georgia) (173)
- [Companies with in-house R&D in Virginia](https://www.tamtam.ai/l/r-and-d-companies-virginia) (166)
- [Companies with in-house R&D in North Carolina](https://www.tamtam.ai/l/r-and-d-companies-north-carolina) (158)
- [Companies with in-house R&D in Wisconsin](https://www.tamtam.ai/l/r-and-d-companies-wisconsin) (154)
- [Companies with in-house R&D in Minnesota](https://www.tamtam.ai/l/r-and-d-companies-minnesota) (146)
- [Companies with in-house R&D in Washington State](https://www.tamtam.ai/l/r-and-d-companies-washington-state) (140)
- [Companies with in-house R&D in Colorado](https://www.tamtam.ai/l/r-and-d-companies-colorado) (113)
- [Companies with in-house R&D in Maryland](https://www.tamtam.ai/l/r-and-d-companies-maryland) (107)
- [Companies with in-house R&D in Indiana](https://www.tamtam.ai/l/r-and-d-companies-indiana) (104)
- [Companies with in-house R&D in New York](https://www.tamtam.ai/l/r-and-d-companies-new-york) (223)
- [Companies with in-house R&D in San Francisco](https://www.tamtam.ai/l/r-and-d-companies-san-francisco) (147)
- [Companies with in-house R&D in Houston](https://www.tamtam.ai/l/r-and-d-companies-houston) (129)
- [Companies with in-house R&D in San Jose](https://www.tamtam.ai/l/r-and-d-companies-san-jose) (103)

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Source: https://www.tamtam.ai/l/r-and-d-companies-pennsylvania