# Companies with in-house R&D headquartered in Philadelphia

Tamtam tracks 35 companies with in-house R&D headquartered in Philadelphia. This list ranks the 30 largest by number of employees on LinkedIn, led by Comcast, University of Pennsylvania and Penn Medicine, University of Pennsylvania Health System. Their median headcount is 1,935. Half of them were founded in 1904 or later.

This selection of companies with in-house R&D in Philadelphia is dominated by large organizations in healthcare and education. Among the prominent names are Comcast, offering broadband and entertainment, the University of Pennsylvania, an Ivy League institution, Penn Medicine, a leading academic medical center, and Children's Hospital of Philadelphia, specializing in pediatric care. FMC Corporation, focused on agricultural chemicals, and Axalta, a provider of performance coatings, also feature. These companies, each with thousands of employees, represent significant established entities.

The data reveals a strong concentration of institutions founded in the late 19th and early 20th centuries, such as Temple University (1884), FMC Corporation (1883), and Drexel University (1891). However, the list also includes newer companies like Axalta (2013) and Clario (1972), indicating a mix of long-standing establishments and more recently founded firms contributing to the R&D landscape in Philadelphia.

🇺🇸 Philadelphia · 30 companies · Updated Nov 12, 2026

| # | Company | Industry | Headquarters | Employees | Founded |
|---|---|---|---|---|---|
| 1 | [Comcast](https://www.tamtam.ai/c/comcast) (comcast.com)<br>Delivering broadband, mobile, and video products, along with entertainment, sports, news, and theme park experiences; driven by passionate creators and innovators | Telecommunications | 🇺🇸 Philadelphia | 189,000 | 1963 |
| 2 | [University of Pennsylvania](https://www.tamtam.ai/c/university-of-pennsylvania) (upenn.edu)<br>Renowned Ivy League university with 12 schools offering a wide range of programs including arts, sciences, engineering, business, and medicine | Higher Education | 🇺🇸 Philadelphia | 22,558 | 1740 |
| 3 | [Penn Medicine, University of Pennsylvania Health System](https://www.tamtam.ai/c/penn-medicine-university-of-pennsylvania-health-system) (pennmedicine.org)<br>Leading academic medical center combining cutting-edge research, comprehensive patient care, and education to improve health and transform lives regionally. | Hospitals and Health Care | 🇺🇸 Philadelphia | 21,979 |  |
| 4 | [Children's Hospital of Philadelphia](https://www.tamtam.ai/c/children-s-hospital-of-philadelphia) (chop.edu)<br>Specialized pediatric hospital providing exceptional patient care, pioneering medical research, and training future pediatric healthcare professionals. | Hospitals and Health Care | 🇺🇸 Philadelphia | 18,042 | 1855 |
| 5 | [Temple University](https://www.tamtam.ai/c/temple-university) (temple.edu)<br>A top-tier research institution in a vibrant city, offering diverse degree programs to prepare future leaders for impactful careers | Higher Education | 🇺🇸 Philadelphia | 13,124 | 1884 |
| 6 | [FMC Corporation](https://www.tamtam.ai/c/fmc-corporation) (fmc.com)<br>The company is dedicated to innovating sustainable technologies to protect crops, support farmers, and tackle agriculture's challenges using science | Agricultural Chemical Manufacturing | 🇺🇸 Philadelphia | 11,986 | 1883 |
| 7 | [Axalta](https://www.tamtam.ai/c/axalta) (axalta.com)<br>A global provider of performance coatings for industrial, automotive, and refinish applications, focused on innovation for a sustainable future | Chemical Manufacturing | 🇺🇸 Philadelphia | 7,744 | 2013 |
| 8 | [Drexel University](https://www.tamtam.ai/c/drexel-university) (drexel.edu)<br>Academically comprehensive urban research university with a globally engaged community and a premier cooperative education program nationwide. | Higher Education | 🇺🇸 Philadelphia | 7,580 | 1891 |
| 9 | [Clario](https://www.tamtam.ai/c/clario-philadelphia) (clario.com)<br>A leading healthcare research and technology company providing expertise and technology for advancing clinical trials in various therapeutic areas worldwide | Biotechnology Research | 🇺🇸 Philadelphia | 7,151 | 1972 |
| 10 | [Temple Health – Temple University Health System](https://www.tamtam.ai/c/temple-health-temple-university-health-system) (templehealth.org)<br>Temple Health provides advanced research and clinical care, offering innovative treatments through renowned physicians, nurses, and researchers in various medical facilities and practices | Hospitals and Health Care | 🇺🇸 Philadelphia | 5,770 | 1892 |
| 11 | [Thomas Jefferson University](https://www.tamtam.ai/c/thomas-jefferson-university) (jefferson.edu)<br>University focused on innovative health education, interdisciplinary learning, expert faculty collaboration, and redefining possibilities in health, education, and discovery. | Higher Education | 🇺🇸 Philadelphia | 5,700 | 1824 |
| 12 | [PCI Pharma Services](https://www.tamtam.ai/c/pci-pharma-services) (pci.com)<br>Provides world-class solutions for drug development, manufacturing, advanced drug delivery, clinical trials, and commercial packaging, delivering life-changing therapies globally. | Pharmaceutical Manufacturing | 🇺🇸 Philadelphia | 4,795 |  |
| 13 | [Carpenter Technology Corporation](https://www.tamtam.ai/c/carpenter-technology-corporation) (carpentertechnology.com)<br>Producer and distributor of premium specialty alloys and advanced materials for aerospace, transportation, medical, energy, and additive manufacturing applications. | Manufacturing | 🇺🇸 Philadelphia | 3,271 | 1889 |
| 14 | [Fox Chase Cancer Center](https://www.tamtam.ai/c/fox-chase-cancer-center) (foxchase.org)<br>Dedicated cancer hospital with expert multidisciplinary teams advancing prevention, diagnosis, treatment, and survivorship through pioneering research and clinical care. | Hospitals and Health Care | 🇺🇸 Philadelphia | 2,146 | 1904 |
| 15 | [Drexel University College of Medicine](https://www.tamtam.ai/c/drexel-university-college-of-medicine) (drexel.edu)<br>A prestigious medical school offering MD and graduate programs, committed to diversity and excellence in medical education and research | Higher Education | 🇺🇸 Philadelphia | 1,935 | 2002 |
| 16 | [Spark Therapeutics, Inc.](https://www.tamtam.ai/c/spark-therapeutics-inc) (sparktx.com)<br>Leading gene therapy company focused on treating inherited diseases through innovative science, integrated expertise, and commitment to accelerating healthcare transformation globally | Biotechnology Research | 🇺🇸 Philadelphia | 1,035 | 2013 |
| 17 | [Temple University - Lewis Katz School of Medicine](https://www.tamtam.ai/c/temple-university-lewis-katz-school-of-medicine) (temple.edu)<br>Leading medical school offering humanistic education, top clinical training, and groundbreaking research, recognized internationally, honored nationally, and essential locally | Higher Education | 🇺🇸 Philadelphia | 1,015 |  |
| 18 | [Federal Reserve Bank of Philadelphia](https://www.tamtam.ai/c/federal-reserve-bank-of-philadelphia) (philadelphiafed.org)<br>Implement monetary policy, supervise banks, provide financial services to institutions and government One of 12 regional Reserve Banks in Federal Reserve System | Financial Services | 🇺🇸 Philadelphia | 852 | 1914 |
| 19 | [Cardone Industries](https://www.tamtam.ai/c/cardone-industries) (cardone.com)<br>A global supplier of remanufactured and new automotive parts for cars and trucks, with over 50 years of experience in delivering high-quality products | Motor Vehicle Manufacturing | 🇺🇸 Philadelphia | 785 | 1970 |
| 20 | [Naval Surface Warfare Center Philadelphia Division](https://www.tamtam.ai/c/naval-surface-warfare-center-philadelphia-division) (navsea.navy.mil)<br>Specializing in naval machinery research, development, cybersecurity, and engineering, providing technical expertise for the Navy's fleet support and innovation | Armed Forces | 🇺🇸 Philadelphia | 768 |  |
| 21 | [NBME](https://www.tamtam.ai/c/nbme) (nbme.org)<br>NBME provides high-quality assessments and educational services for students, professionals, educators, and institutions in the medical education and healthcare fields | Education Administration Programs | 🇺🇸 Philadelphia | 733 | 1915 |
| 22 | [AgroFresh](https://www.tamtam.ai/c/agrofresh) (agrofresh.com)<br>AgroFresh empowers fresh produce businesses with science-based solutions to enhance quality, extend shelf life, prevent food waste, and preserve resources | Biotechnology Research | 🇺🇸 Philadelphia | 726 | 1996 |
| 23 | [Adare Pharma Solutions](https://www.tamtam.ai/c/adare-pharma-solutions) (adarepharmasolutions.com)<br>providing end-to-end integrated services from product development to commercial manufacturing and packaging with expertise in oral dosage forms and specialized technology platforms. | Pharmaceutical Manufacturing | 🇺🇸 Philadelphia | 597 |  |
| 24 | [Wills Eye Hospital](https://www.tamtam.ai/c/wills-eye-hospital) (willseye.org)<br>A global leader in eye disease treatment, providing top-notch care, cutting-edge technology, and advanced surgical capabilities to patients worldwide since 1832 | Hospitals and Health Care | 🇺🇸 Philadelphia | 556 | 1832 |
| 25 | [University of Pennsylvania Graduate School of Education](https://www.tamtam.ai/c/university-of-pennsylvania-graduate-school-of-education) (gse.upenn.edu)<br>A pioneer in education research, innovation, and leadership development, offering top-ranked graduate programs and a diverse, inclusive community of professionals | Higher Education | 🇺🇸 Philadelphia | 443 | 1893 |
| 26 | [University of Pennsylvania School of Veterinary Medicine](https://www.tamtam.ai/c/university-of-pennsylvania-school-of-veterinary-medicine) (vet.upenn.edu)<br>Innovative approach to veterinary medicine, providing medical treatments, public health vigilance, and education on animal and human health connections | Higher Education | 🇺🇸 Philadelphia | 377 | 1884 |
| 27 | [Tastepoint by IFF](https://www.tamtam.ai/c/tastepoint-by-iff) (tastepoint.com)<br>Tastepoint blends passion and technology to provide innovative taste solutions, creating delightful experiences for customers and consumers | Food and Beverage Services | 🇺🇸 Philadelphia | 375 | 2017 |
| 28 | [Penn Dental Medicine](https://www.tamtam.ai/c/penn-dental-medicine) (dental.upenn.edu)<br>Private, Ivy-League institution with a history deeply rooted in forging precedents in dental education, research, and patient care. Dentistry taught as a specialty of medicine. | Higher Education | 🇺🇸 Philadelphia | 312 | 1878 |
| 29 | [Sidney Kimmel Comprehensive Cancer Center at Jefferson](https://www.tamtam.ai/c/sidney-kimmel-comprehensive-cancer-center-at-jefferson) (jeffersonhealth.org)<br>A leading cancer center focused on research, patient care, and education in Greater Philadelphia, striving to improve lives through innovation and breakthroughs #CancerCure | Hospitals and Health Care | 🇺🇸 Philadelphia | 244 | 1996 |
| 30 | [Kingsbury, Inc.®](https://www.tamtam.ai/c/kingsbury-inc) (kingsbury.com)<br>A legacy company known for innovative fluid film bearings and tailored solutions for industrial applications, focusing on quality, sustainability, and customer satisfaction | Industrial Machinery Manufacturing | 🇺🇸 Philadelphia | 229 | 1912 |

## How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 12, 2026.

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## The same list elsewhere in United States

- [Companies with in-house R&D in the United States](https://www.tamtam.ai/l/r-and-d-companies-united-states) (6,796)
- [Companies with in-house R&D in California](https://www.tamtam.ai/l/r-and-d-companies-california) (1,275)
- [Companies with in-house R&D in Texas](https://www.tamtam.ai/l/r-and-d-companies-texas) (442)
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- [Companies with in-house R&D in Michigan](https://www.tamtam.ai/l/r-and-d-companies-michigan) (287)
- [Companies with in-house R&D in Ohio](https://www.tamtam.ai/l/r-and-d-companies-ohio) (277)
- [Companies with in-house R&D in Pennsylvania](https://www.tamtam.ai/l/r-and-d-companies-pennsylvania) (255)
- [Companies with in-house R&D in New Jersey](https://www.tamtam.ai/l/r-and-d-companies-new-jersey) (224)
- [Companies with in-house R&D in Florida](https://www.tamtam.ai/l/r-and-d-companies-florida) (221)
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- [Companies with in-house R&D in Georgia](https://www.tamtam.ai/l/r-and-d-companies-georgia) (173)
- [Companies with in-house R&D in Virginia](https://www.tamtam.ai/l/r-and-d-companies-virginia) (166)
- [Companies with in-house R&D in North Carolina](https://www.tamtam.ai/l/r-and-d-companies-north-carolina) (158)
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## The same list elsewhere

- [Companies with in-house R&D in the world](https://www.tamtam.ai/l/r-and-d-companies-in-the-world) (34,346)
- [Companies with in-house R&D in North America](https://www.tamtam.ai/l/r-and-d-companies-in-north-america) (7,619)

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Source: https://www.tamtam.ai/l/r-and-d-companies-philadelphia