# 30 leading companies with in-house R&D in Rome
Tamtam tracks 82 companies with in-house R&D headquartered in Rome. This list ranks the 30 largest by number of employees on LinkedIn, led by Leonardo, Eni and Enel Group. Their median headcount is 2,070. Half of them were founded in 1961 or later.
These large Rome-based companies conduct in-house research and development. The list comprises established organizations, many of which are publicly owned or have a strong public service component. They operate in sectors such as defense, energy, utilities, and research.
Key players include Leonardo, a multinational specializing in aerospace and cybersecurity; Eni, an integrated energy business; Enel Group, a leading electricity operator; and Ferrovie dello Stato Italiane S.p.A., managing national rail infrastructure. Sapienza Universitร di Roma and Consiglio Nazionale delle Ricerche are prominent research institutions. A notable pattern is the dominance of large, often state-backed, entities across critical infrastructure and public services.
๐ฎ๐น Rome ยท 30 companies ยท Updated Nov 11, 2026
| # | Company | Industry | Headquarters | Employees | Founded |
|---|---|---|---|---|---|
| 1 | [Leonardo](https://www.tamtam.ai/c/leonardo) (leonardo.com)
Defense and security multinational company specializing in aerospace, cybersecurity, military systems, and advanced technology solutions | Defense and Space Manufacturing | ๐ฎ๐น Rome | 38,521 | 1948 |
| 2 | [Eni](https://www.tamtam.ai/c/eni) (eni.com)
Integrated energy business, decarbonized products, renewable and retail, bio-refineries, biomethane, low-carbon energy, mobility services. | Oil and Gas | ๐ฎ๐น Rome | 32,259 | |
| 3 | [Enel Group](https://www.tamtam.ai/c/enel-group) (enel.com)
Multinational company reshaping the future of energy, a leading integrated electricity operator. Distributes and supplies electricity to millions of end users. | Utilities | ๐ฎ๐น Rome | 31,218 | 1962 |
| 4 | [Ferrovie dello Stato Italiane S.p.A.](https://www.tamtam.ai/c/ferrovie-dello-stato-italiane-s-p-a) (fsitaliane.it)
National rail infrastructure management, passenger transport services, logistics solutions, and urban regeneration projects across Italy. | Facilities Services | ๐ฎ๐น Rome | 28,071 | |
| 5 | [Sapienza Universitร di Roma](https://www.tamtam.ai/c/sapienza-universita-di-roma) (uniroma1.it)
A prestigious, historic university in Rome with a diverse range of academic programs, research opportunities, and international exchange programs for students and academics | Research Services | ๐ฎ๐น Rome | 16,981 | 1303 |
| 6 | [Engineering Group](https://www.tamtam.ai/c/engineering-group) (eng.it)
Leading digital transformation company with global presence, specializing in innovation, proprietary solutions, R&D, and diverse market expertise. | IT Services and IT Consulting | ๐ฎ๐น Rome | 11,815 | 1980 |
| 7 | [Consiglio Nazionale delle Ricerche](https://www.tamtam.ai/c/consiglio-nazionale-delle-ricerche) (cnr.it)
A public organization in Italy that conducts and promotes interdisciplinary research in various sectors for scientific, technological, and social development | Research Services | ๐ฎ๐น Rome | 6,744 | 1923 |
| 8 | [Terna SpA](https://www.tamtam.ai/c/terna-spa) (terna.it)
An Italian energy transmission grid operator focused on ensuring the safety, quality, and cost-effectiveness of the electricity system while promoting sustainability and innovation | Utilities | ๐ฎ๐น Rome | 5,058 | 1999 |
| 9 | [INAIL, Istituto Nazionale Assicurazione contro gli Infortuni sul Lavoro](https://www.tamtam.ai/c/inail-istituto-nazionale-assicurazione-contro-gli-infortuni-sul-lavoro) (inail.it)
A public non-profit entity founded in 1883, provides insurance for all workers against work-related accidents, disabilities, health damage, and occupational diseases Additionally, supports injured workers with rehabilitation and reintegration assistance | Government Administration | ๐ฎ๐น Rome | 4,031 | 1883 |
| 10 | [Fondazione Policlinico Universitario Agostino Gemelli IRCCS](https://www.tamtam.ai/c/fondazione-policlinico-universitario-agostino-gemelli-irccs) (policlinicogemelli.it)
A leading Italian hospital specializing in personalized medicine, innovative biotechnologies, and clinical care for a wide range of specialties, including oncology and rare diseases | Hospitals and Health Care | ๐ฎ๐น Rome | 3,810 | |
| 11 | [Telespazio](https://www.tamtam.ai/c/telespazio) (telespazio.com)
Provides comprehensive space services, from system design to satellite control, Earth observation, communication, and navigation, utilizing AI for advanced applications improving life and addressing climate change. | Defense and Space Manufacturing | ๐ฎ๐น Rome | 2,864 | 1961 |
| 12 | [ENEA](https://www.tamtam.ai/c/enea) (enea.it)
An Italian organization specialized in research, development, and promotion of technologies for energy efficiency, renewable sources, nuclear energy, environmental protection, and more | Research Services | ๐ฎ๐น Rome | 2,659 | |
| 13 | [INFN](https://www.tamtam.ai/c/infn) (infn.it)
An Italian research organization specializing in subnuclear, nuclear, and astroparticle physics, developing advanced technologies and collaborating with industry and academia | Research Services | ๐ฎ๐น Rome | 2,332 | 1951 |
| 14 | [Translated](https://www.tamtam.ai/c/translated) (translated.com)
A leading provider of human translation services in 150+ languages, combining human creativity and machine intelligence for speedy, high-quality translations | Translation and Localization | ๐ฎ๐น Rome | 2,070 | 1999 |
| 15 | [Angelini Pharma](https://www.tamtam.ai/c/angelini-pharma) (angelinipharma.com)
A pharmaceutical company dedicated to developing new medicines and solutions for patients, with a focus on CNS, mental health, and consumer health | Pharmaceutical Manufacturing | ๐ฎ๐น Rome | 2,043 | 1919 |
| 16 | [ELT Group](https://www.tamtam.ai/c/elt-group) (eltgroup.net)
A global leader in electronic defense systems, specializing in managing the electromagnetic spectrum and offering technology solutions for defense, cyber, space, and biodefense | Defense and Space Manufacturing | ๐ฎ๐น Rome | 1,728 | 1951 |
| 17 | [Angelini Industries](https://www.tamtam.ai/c/angelini-industries) (angeliniindustries.com)
Operates globally in health, industrial technology, and consumer goods sectors, focusing on growth, R&D, environmental impact reduction, and worker safety. | Manufacturing | ๐ฎ๐น Rome | 2,855 | |
| 18 | [Italtel](https://www.tamtam.ai/c/italtel) (italtel.com)
The company provides communication technology solutions, integrates traditional and new technologies, offers managed services, and focuses on sustainability and inclusivity | Telecommunications | ๐ฎ๐น Rome | 1,398 | 1921 |
| 19 | [CREA Ricerca](https://www.tamtam.ai/c/crea-ricerca) (crea.gov.it)
Leading Italian research organization focused on agri-food supply chains Innovative and sustainable solutions in agriculture, livestock, food science, and socio-economics Promoting circular economy and consumer protection | Research Services | ๐ฎ๐น Rome | 1,128 | 2015 |
| 20 | [KT - Kinetics Technology](https://www.tamtam.ai/c/kt-kinetics-technology) (kt-met.com)
Specialized EPC Contractor for refining industry, offering integrated engineering solutions with focus on process design, licensing, sulphur recovery, and hydrogen/syngas production | Oil and Gas | ๐ฎ๐น Rome | 1,088 | 1971 |
| 21 | [Istituto Poligrafico e Zecca dello Stato (IPZS)](https://www.tamtam.ai/c/istituto-poligrafico-e-zecca-dello-stato-ipzs) (ipzs.it)
The company protects citizens' physical and digital identities, secures sensitive data, ensures production reliability, and enhances cultural heritage through tailored solutions and products | Printing Services | ๐ฎ๐น Rome | 1,038 | 1928 |
| 22 | [San Raffaele](https://www.tamtam.ai/c/san-raffaele) (sanraffaele.it)
A leading healthcare organization providing excellence in research, rehabilitation, and patient care with a network of facilities and specialists across Italy | Hospitals and Health Care | ๐ฎ๐น Rome | 944 | |
| 23 | [Universitร degli Studi Niccolรฒ Cusano](https://www.tamtam.ai/c/universita-degli-studi-niccolo-cusano) (unicusano.it)
An online university established in 2006, with a campus in Rome including dorms, sports facilities, a theater, and a Medical-Scientific Research Center | Higher Education | ๐ฎ๐น Rome | 922 | 2006 |
| 24 | [Istituto Nazionale di Geofisica e Vulcanologia](https://www.tamtam.ai/c/istituto-nazionale-di-geofisica-e-vulcanologia) (ingv.it)
The company specializes in monitoring geophysical phenomena, such as seismic activity and volcanic eruptions, in Italy through advanced instrumentation and collaboration with universities and research institutions | Research Services | ๐ฎ๐น Rome | 916 | 1841 |
| 25 | [Amplia Infrastructures](https://www.tamtam.ai/c/amplia-infrastructures) (ampliaspa.it)
A construction company specializing in roads, motorways, bridges, airports, and road surface materials International presence in Eastern Europe, Middle East, and South America | Construction | ๐ฎ๐น Rome | 891 | |
| 26 | [Topnetwork S.p.A.](https://www.tamtam.ai/c/topnetwork-s-p-a) (topnetwork.it)
A service agency supporting digital transformation with innovative solutions, integrating AI, blockchain, Cloud, Data Science, IoT, robotics, and more | IT Services and IT Consulting | ๐ฎ๐น Rome | 836 | 2003 |
| 27 | [Fondazione Santa Lucia](https://www.tamtam.ai/c/fondazione-santa-lucia) (fondazionesantalucia.it)
Specializing in neurorehabilitation, the organization provides autonomy and quality of life for adults and children through research and high levels of care | Hospitals and Health Care | ๐ฎ๐น Rome | 823 | 1960 |
| 28 | [INAF Istituto Nazionale di Astrofisica](https://www.tamtam.ai/c/inaf-istituto-nazionale-di-astrofisica) (inaf.it)
The company promotes, coordinates, and conducts research in Astronomy, Radioastronomy, Space Astrophysics, and Cosmic Physics It also promotes astronomy education in schools and society | Research Services | ๐ฎ๐น Rome | 777 | 1999 |
| 29 | [Sogin](https://www.tamtam.ai/c/sogin) (sogin.it)
Italian state-owned organization managing nuclear site decontamination, radioactive waste, and decommissioning projects for power plants, research centers, and repositories | Oil and Gas | ๐ฎ๐น Rome | 696 | 1999 |
| 30 | [MSD Italia](https://www.tamtam.ai/c/msd-italia) (msd-italia.it)
A multinational pharmaceutical leader dedicated to discovering innovative products and services to save and improve patients' lives worldwide | Pharmaceutical Manufacturing | ๐ฎ๐น Rome | 598 | |
## How this list is built
Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 11, 2026.
## More company lists in Rome
- [The largest companies in Rome](https://www.tamtam.ai/l/largest-companies-rome) (1,036)
- [Multinational companies in Rome](https://www.tamtam.ai/l/multinational-companies-rome) (196)
- [Retail chains in Rome](https://www.tamtam.ai/l/retail-chains-rome) (99)
- [Critical infrastructure operators in Rome](https://www.tamtam.ai/l/critical-infrastructure-operators-rome) (92)
- [Financial services firms in Rome](https://www.tamtam.ai/l/financial-services-firms-rome) (92)
- [Public sector organisations in Rome](https://www.tamtam.ai/l/public-sector-organisations-rome) (92)
- [IT services companies in Rome](https://www.tamtam.ai/l/it-services-companies-rome) (73)
- [IT Services and IT Consulting companies in Rome](https://www.tamtam.ai/l/it-services-and-it-consulting-companies-rome) (72)
- [Companies with a mobile app in Rome](https://www.tamtam.ai/l/companies-with-mobile-app-rome) (62)
- [Financial Services companies in Rome](https://www.tamtam.ai/l/financial-services-companies-rome) (58)
- [Consulting firms in Rome](https://www.tamtam.ai/l/consulting-firms-rome) (56)
- [Education providers in Rome](https://www.tamtam.ai/l/education-companies-rome) (56)
- [Professional services firms in Rome](https://www.tamtam.ai/l/professional-services-firms-rome) (52)
- [Software Development companies in Rome](https://www.tamtam.ai/l/software-development-companies-rome) (46)
- [Corporate groups and holding companies in Rome](https://www.tamtam.ai/l/holding-companies-rome) (46)
- [Hospitality companies in Rome](https://www.tamtam.ai/l/hospitality-companies-rome) (42)
- [Government Administration companies in Rome](https://www.tamtam.ai/l/government-administration-companies-rome) (38)
- [Hotel and hospitality groups in Rome](https://www.tamtam.ai/l/hospitality-groups-rome) (36)
- [Luxury brands in Rome](https://www.tamtam.ai/l/luxury-brands-rome) (36)
- [Manufacturers in Rome](https://www.tamtam.ai/l/manufacturers-rome) (36)
- [Healthcare providers in Rome](https://www.tamtam.ai/l/healthcare-providers-rome) (35)
- [E-commerce companies in Rome](https://www.tamtam.ai/l/ecommerce-companies-rome) (34)
- [Family-owned companies in Rome](https://www.tamtam.ai/l/family-owned-companies-rome) (34)
- [Entertainment Providers companies in Rome](https://www.tamtam.ai/l/entertainment-providers-companies-rome) (31)
## The same list elsewhere in Italy
- [Companies with in-house R&D in Italy](https://www.tamtam.ai/l/r-and-d-companies-italy) (1,418)
- [Companies with in-house R&D in Lombardy](https://www.tamtam.ai/l/r-and-d-companies-lombardy) (432)
- [Companies with in-house R&D in Emilia-Romagna](https://www.tamtam.ai/l/r-and-d-companies-emilia-romagna) (195)
- [Companies with in-house R&D in Veneto](https://www.tamtam.ai/l/r-and-d-companies-veneto) (182)
- [Companies with in-house R&D in Lazio](https://www.tamtam.ai/l/r-and-d-companies-lazio) (120)
- [Companies with in-house R&D in Piedmont](https://www.tamtam.ai/l/r-and-d-companies-piedmont) (102)
- [Companies with in-house R&D in Tuscany](https://www.tamtam.ai/l/r-and-d-companies-tuscany) (80)
- [Companies with in-house R&D in Campania](https://www.tamtam.ai/l/r-and-d-companies-campania) (44)
- [Companies with in-house R&D in Friuli-Venezia Giulia](https://www.tamtam.ai/l/r-and-d-companies-friuli-venezia-giulia) (43)
- [Companies with in-house R&D in the Marche](https://www.tamtam.ai/l/r-and-d-companies-marche) (34)
- [Companies with in-house R&D in Apulia](https://www.tamtam.ai/l/r-and-d-companies-apulia) (26)
- [Companies with in-house R&D in Trentino-South Tyrol](https://www.tamtam.ai/l/r-and-d-companies-trentino-south-tyrol) (25)
- [Companies with in-house R&D in Milan](https://www.tamtam.ai/l/r-and-d-companies-milan) (124)
- [Companies with in-house R&D in Turin](https://www.tamtam.ai/l/r-and-d-companies-turin) (31)
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Source: https://www.tamtam.ai/l/r-and-d-companies-rome