# The 30 largest companies with in-house R&D in San Francisco
Tamtam tracks 147 companies with in-house R&D headquartered in San Francisco. This list ranks the 30 largest by number of employees on LinkedIn, led by Uber, Salesforce and DoorDash. Their median headcount is 8,490. Half of them were founded in 2009 or later.
This selection of San Francisco companies with in-house R&D includes large corporations and mid-sized firms. The majority operate in software development, such as Salesforce, which provides customer relationship management solutions, and Databricks, offering a Data Intelligence Platform. Other notable companies include Uber, a global platform for transportation and delivery, and Levi Strauss & Co., which designs and markets denim jeans and apparel.
The data shows a concentration of companies focused on digital platforms and technology. While many are in software, there is also representation from other sectors like retail with Williams-Sonoma, Inc. and healthcare with UCSF Health. The companies listed are all headquartered in San Francisco.
๐บ๐ธ San Francisco ยท 30 companies ยท Updated Nov 11, 2026
| # | Company | Industry | Headquarters | Employees | Founded |
|---|---|---|---|---|---|
| 1 | [Uber](https://www.tamtam.ai/c/uber-san-francisco) (uber.com)
Global platform powering flexible earnings and movement of people and things, constantly reimagining how to enable transportation and delivery services worldwide | Internet Marketplace Platforms | ๐บ๐ธ San Francisco | 160,913 | |
| 2 | [Salesforce](https://www.tamtam.ai/c/salesforce) (salesforce.com)
It provides customer relationship management solutions, integrating data, artificial intelligence, and a focus on trust to enhance customer experiences. | Software Development | ๐บ๐ธ San Francisco | 86,347 | |
| 3 | [DoorDash](https://www.tamtam.ai/c/doordash) (careersatdoordash.com)
A tech and logistics company focused on empowering local economies through delivery services, with a mission to expand beyond food delivery | Software Development | ๐บ๐ธ San Francisco | 80,754 | |
| 4 | [Airbnb](https://www.tamtam.ai/c/airbnb) (airbnb.com)
The company offers unique stays and experiences worldwide through a platform connecting hosts with guests, fostering community connections | Software Development | ๐บ๐ธ San Francisco | 72,938 | 2007 |
| 5 | [Rodan + Fields](https://www.tamtam.ai/c/rodan-fields) (rodanandfields.com)
A skincare company founded by dermatologists focusing on giving people the best skin and confidence, with a commitment to social impact | Manufacturing | ๐บ๐ธ San Francisco | 17,749 | 2000 |
| 6 | [Levi Strauss & Co.](https://www.tamtam.ai/c/levi-strauss-and-co) (levistrauss.com)
designs and markets iconic denim jeans and apparel brands, emphasizing sustainability, innovation, and global self-expression through fashion. | Retail Apparel and Fashion | ๐บ๐ธ San Francisco | 17,743 | 1853 |
| 7 | [Databricks](https://www.tamtam.ai/c/databricks) (databricks.com)
It provides a Data Intelligence Platform for organizations to manage their data effectively and leverage AI for better decision-making. | Software Development | ๐บ๐ธ San Francisco | 15,896 | |
| 8 | [Williams-Sonoma, Inc.](https://www.tamtam.ai/c/williams-sonoma-inc) (williams-sonomainc.com)
Specialty retailer offering high-quality kitchenware, furniture, and home decor through brands like Pottery Barn and West Elm across global multi-channel retail platforms. | Retail | ๐บ๐ธ San Francisco | 15,546 | |
| 9 | [Autodesk](https://www.tamtam.ai/c/autodesk) (autodesk.com)
It provides software for architecture, engineering, construction, and media, enabling users to design, collaborate, and solve various challenges effectively. | Software Development | ๐บ๐ธ San Francisco | 15,378 | 1982 |
| 10 | [Pinterest](https://www.tamtam.ai/c/pinterest) (pinterest.com)
It is a visual inspiration platform with 482 million monthly active users, helping people search, save, and shop ideas. | Software Development | ๐บ๐ธ San Francisco | 13,766 | 2010 |
| 11 | [UCSF Health](https://www.tamtam.ai/c/ucsf-health) (ucsfhealth.org)
An integrated healthcare network with top-ranked hospitals, providing innovative patient care, advanced technology, pioneering research, and compassionate treatment across numerous specialties. | Hospitals and Health Care | ๐บ๐ธ San Francisco | 11,588 | |
| 12 | [Deel](https://www.tamtam.ai/c/deel) (deel.com)
Platform offering HR tools, payroll, compliance, and mobility services to help companies manage and scale international workforces efficiently. | Human Resources Services | ๐บ๐ธ San Francisco | 9,873 | 2019 |
| 13 | [OpenAI](https://www.tamtam.ai/c/openai) (openai.com)
An AI research and deployment company focused on creating safe and beneficial general-purpose artificial intelligence for the benefit of humanity | Research Services | ๐บ๐ธ San Francisco | 9,268 | 2015 |
| 14 | [Splunk](https://www.tamtam.ai/c/splunk) (splunk.com)
Providing organizations with a unified security and observability platform to ensure operational resilience in the face of digital disruptions | Software Development | ๐บ๐ธ San Francisco | 8,820 | |
| 15 | [Docusign](https://www.tamtam.ai/c/docusign) (docusign.com)
It provides e-signature and contract lifecycle management solutions, helping businesses streamline agreement processes and unlock valuable data trapped in documents. | Software Development | ๐บ๐ธ San Francisco | 8,490 | 2003 |
| 16 | [Gensler](https://www.tamtam.ai/c/gensler) (gensler.com)
Global architecture, design, and planning firm with a network of 6,000+ professionals creating positive change through impactful design across various sectors worldwide | Architecture and Planning | ๐บ๐ธ San Francisco | 8,363 | 1965 |
| 17 | [Rippling](https://www.tamtam.ai/c/rippling) (rippling.com)
Workforce management system streamlining business operations by consolidating data and applications for payroll, IT, expenses, and more into one unified platform | Software Development | ๐บ๐ธ San Francisco | 7,811 | 2016 |
| 18 | [Okta](https://www.tamtam.ai/c/okta) (okta.com)
A platform that prioritizes identity management by offering neutrality, power, and flexibility, tailored to various industries, use cases, and support levels | Software Development | ๐บ๐ธ San Francisco | 7,522 | 2009 |
| 19 | [Cloudflare](https://www.tamtam.ai/c/cloudflare) (cloudflare.com)
The company is a leading connectivity cloud provider, empowering organizations to enhance speed and security while reducing complexity and cost | Computer and Network Security | ๐บ๐ธ San Francisco | 7,489 | 2009 |
| 20 | [Unity](https://www.tamtam.ai/c/unity) (unity.com)
Platform providing software solutions for creating, running, and monetizing interactive real-time 2D and 3D content across devices. | Software Development | ๐บ๐ธ San Francisco | 7,154 | |
| 21 | [Twilio](https://www.tamtam.ai/c/twilio) (twilio.com)
Platform enabling companies to build personalized customer relationships using communications and data across sales, marketing, service, and growth worldwide. | Software Development | ๐บ๐ธ San Francisco | 6,921 | 2008 |
| 22 | [Zendesk](https://www.tamtam.ai/c/zendesk) (zdsk.co)
It provides a customer service platform that connects brands with customers through various communication channels, enhancing customer experience globally. | Software Development | ๐บ๐ธ San Francisco | 6,874 | 2007 |
| 23 | [SoFi](https://www.tamtam.ai/c/sofi) (sofi.com)
Values-driven company providing modern financial products & services to help members borrow, save, spend, invest, and protect their money for financial independence | Financial Services | ๐บ๐ธ San Francisco | 6,754 | 2011 |
| 24 | [GitHub](https://www.tamtam.ai/c/github) (github.com)
It serves as a global platform for developers to collaborate, build, and deliver secure software using AI-powered tools and features. | Software Development | ๐บ๐ธ San Francisco | 6,506 | 2008 |
| 25 | [Notion](https://www.tamtam.ai/c/notion) (notion.com)
Combines product roadmaps, company wikis, and meeting notes into a single customizable workspace allowing teams to build and modify their own software tools. | Software Development | ๐บ๐ธ San Francisco | 6,434 | 2016 |
| 26 | [Square](https://www.tamtam.ai/c/square) (squareup.com)
It provides integrated software and financial services to help sellers manage sales, inventory, and cash flow across various channels. | Software Development | ๐บ๐ธ San Francisco | 6,380 | 2009 |
| 27 | [Samsara](https://www.tamtam.ai/c/samsara) (samsara.com)
A pioneer in Connected Operationsโข Cloud, leveraging IoT data for actionable insights to improve operations in various industries worldwide | Software Development | ๐บ๐ธ San Francisco | 5,639 | 2015 |
| 28 | [Elastic](https://www.tamtam.ai/c/elastic) (elastic.co)
This company specializes in Enterprise Search, Observability, and Security solutions to enhance customer and employee experiences, ensure smooth application performance, and protect against cyber threats | Software Development | ๐บ๐ธ San Francisco | 5,089 | |
| 29 | [Gusto](https://www.tamtam.ai/c/gusto) (gusto.com)
A payroll and HR platform providing benefits, insurance, and support to streamline operations for over 300,000 businesses nationwide | Software Development | ๐บ๐ธ San Francisco | 4,450 | 2011 |
| 30 | [Asana](https://www.tamtam.ai/c/asana) (asana.com)
It empowers organizations with a comprehensive platform for managing goals, initiatives, and work execution, serving over 150,000 customers globally. | Software Development | ๐บ๐ธ San Francisco | 4,407 | 2008 |
## How this list is built
Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 11, 2026.
## More company lists in San Francisco
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- [Companies with a mobile app in San Francisco](https://www.tamtam.ai/l/companies-with-mobile-app-san-francisco) (238)
- [Venture-backed startups in San Francisco](https://www.tamtam.ai/l/venture-backed-startups-san-francisco) (227)
- [Technology, Information and Internet companies in San Francisco](https://www.tamtam.ai/l/technology-information-and-internet-companies-san-francisco) (214)
- [Financial Services companies in San Francisco](https://www.tamtam.ai/l/financial-services-companies-san-francisco) (149)
- [IT Services and IT Consulting companies in San Francisco](https://www.tamtam.ai/l/it-services-and-it-consulting-companies-san-francisco) (130)
- [Professional services firms in San Francisco](https://www.tamtam.ai/l/professional-services-firms-san-francisco) (130)
- [Data and analytics companies in San Francisco](https://www.tamtam.ai/l/data-analytics-companies-san-francisco) (115)
- [Financial services firms in San Francisco](https://www.tamtam.ai/l/financial-services-firms-san-francisco) (109)
- [Online-only businesses in San Francisco](https://www.tamtam.ai/l/online-only-businesses-san-francisco) (95)
- [Consulting firms in San Francisco](https://www.tamtam.ai/l/consulting-firms-san-francisco) (88)
- [Education providers in San Francisco](https://www.tamtam.ai/l/education-companies-san-francisco) (86)
- [Fintech companies in San Francisco](https://www.tamtam.ai/l/fintech-companies-san-francisco) (86)
- [IT services companies in San Francisco](https://www.tamtam.ai/l/it-services-companies-san-francisco) (78)
- [Online marketplaces in San Francisco](https://www.tamtam.ai/l/online-marketplaces-san-francisco) (72)
- [E-commerce companies in San Francisco](https://www.tamtam.ai/l/ecommerce-companies-san-francisco) (67)
## The same list elsewhere in United States
- [Companies with in-house R&D in the United States](https://www.tamtam.ai/l/r-and-d-companies-united-states) (6,796)
- [Companies with in-house R&D in California](https://www.tamtam.ai/l/r-and-d-companies-california) (1,276)
- [Companies with in-house R&D in Texas](https://www.tamtam.ai/l/r-and-d-companies-texas) (442)
- [Companies with in-house R&D in New York State](https://www.tamtam.ai/l/r-and-d-companies-new-york-state) (419)
- [Companies with in-house R&D in Massachusetts](https://www.tamtam.ai/l/r-and-d-companies-massachusetts) (396)
- [Companies with in-house R&D in Illinois](https://www.tamtam.ai/l/r-and-d-companies-illinois) (322)
- [Companies with in-house R&D in Michigan](https://www.tamtam.ai/l/r-and-d-companies-michigan) (287)
- [Companies with in-house R&D in Ohio](https://www.tamtam.ai/l/r-and-d-companies-ohio) (277)
- [Companies with in-house R&D in Pennsylvania](https://www.tamtam.ai/l/r-and-d-companies-pennsylvania) (255)
- [Companies with in-house R&D in New Jersey](https://www.tamtam.ai/l/r-and-d-companies-new-jersey) (224)
- [Companies with in-house R&D in Florida](https://www.tamtam.ai/l/r-and-d-companies-florida) (221)
- [Companies with in-house R&D in Alabama](https://www.tamtam.ai/l/r-and-d-companies-alabama) (214)
- [Companies with in-house R&D in Georgia](https://www.tamtam.ai/l/r-and-d-companies-georgia) (173)
- [Companies with in-house R&D in Virginia](https://www.tamtam.ai/l/r-and-d-companies-virginia) (166)
- [Companies with in-house R&D in North Carolina](https://www.tamtam.ai/l/r-and-d-companies-north-carolina) (158)
- [Companies with in-house R&D in Wisconsin](https://www.tamtam.ai/l/r-and-d-companies-wisconsin) (154)
- [Companies with in-house R&D in Minnesota](https://www.tamtam.ai/l/r-and-d-companies-minnesota) (146)
- [Companies with in-house R&D in Washington State](https://www.tamtam.ai/l/r-and-d-companies-washington-state) (140)
- [Companies with in-house R&D in Colorado](https://www.tamtam.ai/l/r-and-d-companies-colorado) (113)
- [Companies with in-house R&D in Maryland](https://www.tamtam.ai/l/r-and-d-companies-maryland) (107)
- [Companies with in-house R&D in Indiana](https://www.tamtam.ai/l/r-and-d-companies-indiana) (104)
- [Companies with in-house R&D in New York](https://www.tamtam.ai/l/r-and-d-companies-new-york) (223)
- [Companies with in-house R&D in Houston](https://www.tamtam.ai/l/r-and-d-companies-houston) (129)
- [Companies with in-house R&D in San Jose](https://www.tamtam.ai/l/r-and-d-companies-san-jose) (103)
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Source: https://www.tamtam.ai/l/r-and-d-companies-san-francisco