# List of companies with in-house R&D in São Paulo State

Tamtam tracks 370 companies with in-house R&D headquartered in São Paulo State. This list ranks the 100 largest by number of employees on LinkedIn, led by JBS, Natura and Einstein Hospital Israelita. Their median headcount is 2,416. Half of them were founded in 1967 or later. The most common headquarters are São Paulo (58), Campinas (9) and São Bernardo do Campo (6).

This list features large companies with in-house R&D operations in São Paulo State. The industries represented include food and beverage manufacturing with JBS, personal care with Natura, and aviation with Embraer, which designs and manufactures aircraft. Healthcare is prominent, with major institutions like Einstein Hospital Israelita and Dasa, Brazil's largest integrated healthcare network. Suzano and Klabin represent the paper and forest product manufacturing sector.

A notable pattern is the concentration of headquarters in the city of São Paulo for many of these large organizations, such as TOTVS, a leading technology company, and Braskem, focused on sustainable chemicals and plastics. Another key sector is manufacturing, with Volkswagen do Brasil producing vehicles and EMS operating in pharmaceutical manufacturing in Hortolandia. The presence of Senai São Paulo and Universidade Estadual Paulista Júlio de Mesquita Filho indicates significant investment in professional training and higher education.

🇧🇷 São Paulo State · 100 companies · Updated Nov 13, 2026

| # | Company | Industry | Headquarters | Employees | Founded |
|---|---|---|---|---|---|
| 1 | [JBS](https://www.tamtam.ai/c/jbs) (jbs.com.br)<br>Global leader in protein-based food production with diverse product portfolio spanning multiple countries and industries, committed to feeding the world with excellence and innovation | Food and Beverage Manufacturing | 🇧🇷 São Paulo | 88,182 | 1953 |
| 2 | [Natura](https://www.tamtam.ai/c/natura) (natura.com.br)<br>A Brazilian multinational in cosmetics and personal care known for sustainable practices, direct sales, cruelty-free and vegan products, and Amazon biodiversity protection | Personal Care Product Manufacturing | 🇧🇷 São Paulo | 47,988 | 1969 |
| 3 | [Einstein Hospital Israelita](https://www.tamtam.ai/c/einstein-hospital-israelita) (einstein.br)<br>A leading healthcare institution offering cutting-edge treatments, compassionate care, social responsibility initiatives, and education and research programs for the community | Hospitals and Health Care | 🇧🇷 São Paulo | 40,979 |  |
| 4 | [Dasa](https://www.tamtam.ai/c/dasa) (dasa.com.br)<br>The company is the largest integrated healthcare network in Brazil, focusing on preventive, predictive, and personalized healthcare with a wide range of services and innovative solutions | Hospitals and Health Care | 🇧🇷 São Paulo | 32,801 | 1999 |
| 5 | [Embraer](https://www.tamtam.ai/c/embraer) (embraer.com)<br>A global aerospace company that designs, manufactures, and services aircraft for commercial, executive, defense, security, and agricultural aviation markets worldwide | Aviation and Aerospace Component Manufacturing | 🇧🇷 São José dos Campos | 25,284 | 1969 |
| 6 | [Suzano](https://www.tamtam.ai/c/suzano) (suzano.com.br)<br>Global leader in sustainable use of natural resources, producing eucalyptus pulp and paper, with innovative solutions promoting renewable bio-based materials worldwide | Paper and Forest Product Manufacturing | 🇧🇷 São Paulo | 23,529 | 1924 |
| 7 | [Sírio-Libanês](https://www.tamtam.ai/c/sirio-libanes) (hospitalsiriolibanes.org.br)<br>A renowned healthcare institution with philanthropic roots, offering top-notch medical services, cutting-edge technology, education, research, and social responsibility initiatives for 100 years | Hospitals and Health Care | 🇧🇷 São Paulo | 19,137 | 1921 |
| 8 | [TOTVS](https://www.tamtam.ai/c/totvs) (totvs.com)<br>A leading technology company in Brazil, providing comprehensive solutions for business digitalization through ERP, financial services, and business performance solutions | Software Development | 🇧🇷 São Paulo | 17,675 |  |
| 9 | [Klabin](https://www.tamtam.ai/c/klabin) (klabin.com.br)<br>A leading producer of renewable and biodegradable paper, cardboard, packaging, and wood products, focused on developing smart solutions for customer needs | Paper and Forest Product Manufacturing | 🇧🇷 São Paulo | 16,499 | 1899 |
| 10 | [EMS](https://www.tamtam.ai/c/ems) (ems.com.br)<br>A leading pharmaceutical organization in Brazil with 45 years of experience, focused on innovation, research, and expanding product lines | Pharmaceutical Manufacturing | 🇧🇷 Hortolandia | 14,399 | 1964 |
| 11 | [Volkswagen do Brasil](https://www.tamtam.ai/c/volkswagen-do-brasil) (vw.com.br)<br>Manufactures innovative cars and mobility solutions, focusing on advanced technologies and people-centric design for the Brazilian market, leading industry future. | Motor Vehicle Manufacturing | 🇧🇷 São Bernardo do Campo | 12,076 | 1953 |
| 12 | [Braskem](https://www.tamtam.ai/c/braskem) (braskem.com)<br>Global company dedicated to sustainable solutions in chemicals and plastics, driving the Circular Economy with innovation and a diverse product portfolio for various industries worldwide | Plastics Manufacturing | 🇧🇷 São Paulo | 10,586 |  |
| 13 | [Votorantim Cimentos](https://www.tamtam.ai/c/votorantim-cimentos) (votorantimcimentos.com.br)<br>A leading international provider of construction materials, with a diverse portfolio including cement, concrete, and aggregates Also active in agricultural inputs and waste management | Construction | 🇧🇷 São Paulo | 9,998 | 1936 |
| 14 | [Senai São Paulo](https://www.tamtam.ai/c/senai-sao-paulo) (sp.senai.br)<br>Industry-managed institution in Brazil and Latin America specializing in professional training for the industrial sector since 1942, with over 85 schools and training centers | Professional Training and Coaching | 🇧🇷 São Paulo | 9,989 | 1942 |
| 15 | [Universidade Estadual Paulista Júlio de Mesquita Filho](https://www.tamtam.ai/c/universidade-estadual-paulista-julio-de-mesquita-filho) (www2.unesp.br)<br>A leading Brazilian university with a multicampus structure offering quality education, research opportunities, and community services to students and society | Higher Education | 🇧🇷 São Paulo | 9,365 | 1976 |
| 16 | [CPFL Energia](https://www.tamtam.ai/c/cpfl-energia) (grupocpfl.com.br)<br>The company has been shaping the history of the Brazilian energy sector for 110 years, with a focus on distribution, generation, transmission, and services | Utilities | 🇧🇷 Campinas | 9,255 | 1912 |
| 17 | [Mercedes-Benz Caminhões e Ônibus](https://www.tamtam.ai/c/mercedes-benz-caminhoes-e-onibus) (mercedes-benz-trucks.com.br)<br>A leading manufacturer of trucks, buses, and automobiles in Brazil, known for quality, technology, and commitment to employee development | Motor Vehicle Manufacturing | 🇧🇷 São Bernardo do Campo | 8,533 | 1956 |
| 18 | [CEJAM - Centro de Estudos e Pesquisas Dr. João Amorim - OFICIAL](https://www.tamtam.ai/c/cejam-centro-de-estudos-e-pesquisas-dr-joao-amorim-oficial) (cejam.org.br)<br>Non-profit institution supporting the Brazilian public health system with over 30 years of experience in primary care, specialized services, emergency care, and hospital management | Hospitals and Health Care | 🇧🇷 São Paulo | 8,271 | 1991 |
| 19 | [Hospital das Clínicas da Faculdade de Medicina da USP](https://www.tamtam.ai/c/hospital-das-clinicas-da-faculdade-de-medicina-da-usp) (hc.fm.usp.br)<br>A public institution affiliated with a medical school in São Paulo, dedicated to health public healthcare through education, research, assistance, and management | Hospitals and Health Care | 🇧🇷 São Paulo | 8,241 | 1944 |
| 20 | [União Química Farmacêutica Nacional](https://www.tamtam.ai/c/uniao-quimica-farmaceutica-nacional) (uniaoquimica.com.br)<br>A pharmaceutical company in Brazil with a strong focus on innovation, social responsibility, and environmental sustainability, offering various benefits to employees | Pharmaceutical Manufacturing | 🇧🇷 São Paulo | 7,519 | 1936 |
| 21 | [Vulcabras](https://www.tamtam.ai/c/vulcabras) (vulcabras.com)<br>Sport-focused organization with multiple brands offering innovative technology and products for athletes, promoting sports participation and sponsoring events and athletes nationally and internationally | Footwear Manufacturing | 🇧🇷 Jundiaí | 7,048 | 1952 |
| 22 | [Aché Laboratórios](https://www.tamtam.ai/c/ache-laboratorios) (ache.com.br)<br>Develops similar drugs, manages a strong portfolio, and continuously develops products and services, promoting health and well-being for the population. | Pharmaceutical Manufacturing | 🇧🇷 Guarulhos | 6,815 | 1966 |
| 23 | [BP - A Beneficência Portuguesa de São Paulo](https://www.tamtam.ai/c/bp-a-beneficencia-portuguesa-de-sao-paulo) (bp.org.br)<br>The organization prioritizes valuing and celebrating life through research, understanding, and technology, with a focus on continuous evolution and respect for all | Hospitals and Health Care | 🇧🇷 São Paulo | 6,759 | 1859 |
| 24 | [A.C.Camargo Cancer Center](https://www.tamtam.ai/c/a-c-camargo-cancer-center) (accamargo.org.br)<br>A specialized center focused on cancer diagnosis, treatment, education, and research with highly specialized healthcare professionals working together in one place | Hospitals and Health Care | 🇧🇷 São Paulo | 6,452 | 1953 |
| 25 | [Uninove - Universidade Nove de Julho](https://www.tamtam.ai/c/uninove-universidade-nove-de-julho) (uninove.br)<br>A leading educational institution in São Paulo offering a wide range of undergraduate, postgraduate, and research programs through innovative teaching methods and state-of-the-art facilities | Higher Education | 🇧🇷 São Paulo | 6,396 | 1954 |
| 26 | [Hypera](https://www.tamtam.ai/c/hypera) (hypera.com.br)<br>Leading Brazilian pharmaceutical company across various segments including consumer health, prescription products, dermocosmetics, and generics, offering high-quality, safe products through continuous innovation. | Pharmaceutical Manufacturing | 🇧🇷 São Paulo | 6,251 | 2001 |
| 27 | [Bosch Brasil](https://www.tamtam.ai/c/bosch-brasil) (bosch.com.br)<br>A global technology supplier offering innovative solutions for smart homes, Industry 40, and connected mobility with a focus on sustainability and safety | Software Development | 🇧🇷 Campinas | 6,246 |  |
| 28 | [Hospital Alemão Oswaldo Cruz](https://www.tamtam.ai/c/hospital-alemao-oswaldo-cruz) (hospitaloswaldocruz.org.br)<br>A leading hospital in Latin America providing comprehensive healthcare services, high complexity treatments, and innovative care models focused on patient-centered approach | Hospitals and Health Care | 🇧🇷 São Paulo | 6,204 | 1897 |
| 29 | [Dexco](https://www.tamtam.ai/c/dexco) (dex.co)<br>We provide aesthetic and functional solutions through our brands, focusing on environmental and social issues, with a strong presence in the Brazilian market | Construction | 🇧🇷 São Paulo | 6,195 |  |
| 30 | [Saint-Gobain Brasil](https://www.tamtam.ai/c/saint-gobain-brasil) (saint-gobain.com.br)<br>A global leader in sustainable construction materials and solutions, operating in 66 countries with a focus on well-being, performance, and sustainability | Wholesale Building Materials | 🇧🇷 São Paulo | 5,593 | 1937 |
| 31 | [Universidade Presbiteriana Mackenzie](https://www.tamtam.ai/c/universidade-presbiteriana-mackenzie) (mackenzie.br)<br>Educates individuals for citizenship, fosters personal and societal development through teaching, research, extension, cultural, sports, social, and spiritual activities, grounded in reformed Christian faith. | Higher Education | 🇧🇷 São Paulo | 5,286 | 1870 |
| 32 | [LIBBS FARMACÊUTICA LTDA](https://www.tamtam.ai/c/libbs-farmaceutica-ltda) (libbs.com.br)<br>A national pharmaceutical company focused on producing healthcare solutions with a strong commitment to research, development, innovation, and social initiatives | Pharmaceutical Manufacturing | 🇧🇷 São Paulo | 5,236 | 1958 |
| 33 | [QuintoAndar](https://www.tamtam.ai/c/quintoandar) (carreiras.quintoandar.com.br)<br>Largest Latin America real estate ecosystem offering diverse brands and innovative technologies to enhance and support all housing journey stages. | Software Development | 🇧🇷 São Paulo | 5,039 | 2012 |
| 34 | [Biolab & Co](https://www.tamtam.ai/c/biolab-and-co) (biolabfarma.com.br)<br>Pharmaceutical innovator in Brazil, offering over 170 products for various health needs Leading in Cardiology, Dermatology, Gynecology, and more | Pharmaceutical Manufacturing | 🇧🇷 São Paulo | 5,014 | 1997 |
| 35 | [Laboratório Cristália](https://www.tamtam.ai/c/laboratorio-cristalia) (cristalia.com.br)<br>Chemical-pharmaceutical laboratory, leading anesthetic and anesthesia adjuvant production in Latin America. Prioritizes innovation and quality in medicine production, affordable prices. | Pharmaceutical Manufacturing | 🇧🇷 Itapira | 4,225 | 1972 |
| 36 | [Whirlpool Latin America](https://www.tamtam.ai/c/whirlpool-latin-america) (whirlpool.com.br)<br>Leading Latin American market in home appliances with popular brands, manufacturing plants, extensive R&D labs, and recognition for innovation and sustainability efforts Visit website for more information | Consumer Goods | 🇧🇷 São Paulo | 4,104 |  |
| 37 | [Instituto do Câncer do Estado de São Paulo - ICESP](https://www.tamtam.ai/c/instituto-do-cancer-do-estado-de-sao-paulo-icesp) (icesp.org.br)<br>A leading oncology center in Latin America, focused on providing high-quality care, education, and research in the public health system | Hospitals and Health Care | 🇧🇷 São Paulo | 4,018 | 2008 |
| 38 | [Hospital de Amor](https://www.tamtam.ai/c/hospital-de-amor) (hospitaldeamor.com.br)<br>Provides specialized cancer treatment for low-income patients, continuously expanding its facilities and services to meet growing demand and strengthen public healthcare. | Hospitals and Health Care | 🇧🇷 Barretos | 3,791 | 1962 |
| 39 | [UTC Engenharia](https://www.tamtam.ai/c/utc-engenharia) (utc.com.br)<br>An industry leader in various sectors including oil & gas, petrochemicals, power generation, and steel production with over 1,000 successful contracts | Construction | 🇧🇷 São Paulo | 3,618 |  |
| 40 | [Ajinomoto do Brasil](https://www.tamtam.ai/c/ajinomoto-do-brasil) (ajinomoto.com.br)<br>Specializing in creating products for various industries using umami flavor, with a focus on food, cosmetics, pharmaceuticals, animal nutrition, and agriculture | Food and Beverage Services | 🇧🇷 São Paulo | 3,618 |  |
| 41 | [Hcor](https://www.tamtam.ai/c/hcor) (hcor.com.br)<br>A leading Brazilian healthcare organization providing specialized medical services, research, training, and social initiatives to make a difference in people's lives | Hospitals and Health Care | 🇧🇷 São Paulo | 3,472 | 1977 |
| 42 | [Oncoclínicas&Co](https://www.tamtam.ai/c/oncoclinicas-and-co) (grupooncoclinicas.com)<br>A leading provider of oncology services in Latin America, offering advanced treatments, multidisciplinary care, and a patient-centered approach across 14 states | Hospitals and Health Care | 🇧🇷 São Paulo | 3,466 | 2010 |
| 43 | [Arco Educação](https://www.tamtam.ai/c/arco-educacao) (arcoeducacao.com.br)<br>A Brazilian company that provides educational solutions for elementary education, developing content, technology, and services for millions of students and schools nationwide | Primary and Secondary Education | 🇧🇷 São Paulo | 3,465 |  |
| 44 | [Scania Latin America](https://www.tamtam.ai/c/scania-latin-america) (scania.com)<br>Leading sustainable transport solutions provider, offering engines for various applications, service products, and financial services Operates globally with focus on R&D in Sweden | Motor Vehicle Manufacturing | 🇧🇷 São Bernardo do Campo | 3,341 | 1957 |
| 45 | [ZARAPLAST S.A.](https://www.tamtam.ai/c/zaraplast-s-a) (zaraplast.com.br)<br>A leading manufacturer of flexible packaging solutions, specializing in plastic rolls for food, cleaning, and hygiene industries ISO 9002 certified for quality | Plastics Manufacturing | 🇧🇷 Cabreúva | 3,199 | 1967 |
| 46 | [Ambipar \| Brasil](https://www.tamtam.ai/c/ambipar-brasil) (ambipar.com)<br>This organization promotes ecological transformation through waste management, water solutions, energy projects, and decarbonization initiatives, focusing on circular economy and environmental regeneration | Environmental Services | 🇧🇷 São Paulo | 3,063 | 1995 |
| 47 | [Pontifícia Universidade Católica de Campinas](https://www.tamtam.ai/c/pontificia-universidade-catolica-de-campinas) (puc-campinas.edu.br)<br>A university in Campinas, focusing on ethical and Christian values, aims to produce, enrich, and disseminate knowledge for professional excellence and holistic human development | Higher Education | 🇧🇷 Campinas | 2,891 | 1941 |
| 48 | [CAST](https://www.tamtam.ai/c/cast-sao-paulo) (cast4it.com)<br>A technology solutions provider with 25 years of experience, offering IT services in finance, industry, services, and the public sector nationally and globally | IT Services and IT Consulting | 🇧🇷 São Paulo | 2,866 | 1990 |
| 49 | [Apsen Farmacêutica](https://www.tamtam.ai/c/apsen-farmaceutica) (apsen.com.br)<br>A pharmaceutical company in Brazil for over 54 years, focused on researching, developing, and providing high-quality medications, prioritizing investment in R&D, HR, and technology | Pharmaceutical Manufacturing | 🇧🇷 São Paulo | 2,556 | 1969 |
| 50 | [Hospital IGESP](https://www.tamtam.ai/c/hospital-igesp) (hospitaligesp.com.br)<br>Specialized hospital founded in the 1950s in São Paulo, offering gastroenterology services and expanding through acquisitions for continued growth | Hospitals and Health Care | 🇧🇷 São Paulo | 2,416 | 1956 |
| 51 | [Blau Farmacêutica](https://www.tamtam.ai/c/blau-farmaceutica) (blau.com)<br>Established in 1987, a leading Brazilian pharmaceutical company specializes in complex medications and biotechnology They operate in various medical sectors nationally and internationally | Pharmaceutical Manufacturing | 🇧🇷 Cotia | 2,399 | 1987 |
| 52 | [Arcor do Brasil](https://www.tamtam.ai/c/arcor-do-brasil) (arcor.com)<br>Manufacturing and selling a variety of high-quality sweets and chocolates, continually expanding its product portfolio and investing in innovation | Food and Beverage Services | 🇧🇷 Campinas | 2,372 | 1981 |
| 53 | [Plascar](https://www.tamtam.ai/c/plascar) (plascar.com.br)<br>Traditional Brazilian company in the automotive sector manufacturing and selling internal and external finishing parts for vehicles for decades | Motor Vehicle Manufacturing | 🇧🇷 Jundiaí | 2,335 | 1963 |
| 54 | [Instituto de Pesquisas ELDORADO](https://www.tamtam.ai/c/instituto-de-pesquisas-eldorado) (org.br)<br>A world-class provider of customized software and hardware solutions for various industries, connecting people, universities, and startups to drive technological innovation globally | IT Services and IT Consulting | 🇧🇷 Campinas | 2,281 | 1999 |
| 55 | [ISA ENERGIA BRASIL](https://www.tamtam.ai/c/isa-energia-brasil) (isaenergiabrasil.com.br)<br>Leading in energy transmission, this organization transports a significant portion of Brazil's electricity annually, ensuring quality and reliability through innovation and improvements | Utilities | 🇧🇷 Morumbi | 2,245 | 1999 |
| 56 | [LongPing High-Tech](https://www.tamtam.ai/c/longping-high-tech) (lpht.com.br)<br>A leading provider of high-quality hybrid corn and sorghum seeds, focusing on research, development, and innovation in agriculture technologies | Farming | 🇧🇷 Cravinhos | 2,222 | 2017 |
| 57 | [CBC - Companhia Brasileira de Cartuchos](https://www.tamtam.ai/c/cbc-companhia-brasileira-de-cartuchos) (cbc.com.br)<br>Manufacturer of a wide range of products for defense, security, sport, and leisure, including innovative ammunition Committed to supporting national and international security forces | Defense and Space Manufacturing | 🇧🇷 Ribeirão Pires | 2,159 | 1926 |
| 58 | [AACD](https://www.tamtam.ai/c/aacd) (aacd.org.br)<br>Established in 1950, this organization provides assistance to children with disabilities through rehabilitation services, professional training, social integration, and resource mobilization efforts | Non-profit Organizations | 🇧🇷 São Paulo | 2,124 | 1950 |
| 59 | [Jacto](https://www.tamtam.ai/c/jacto) (jacto.com)<br>Supplier of high-tech agricultural equipment for pruning, spraying, harvesting, and planting, as well as solutions for precision and digital agriculture Sustainable production focus | Machinery Manufacturing | 🇧🇷 Pompeia | 2,001 | 1948 |
| 60 | [Santista](https://www.tamtam.ai/c/santista) (santistasa.com.br)<br>A prestigious holding company with a focus on innovation, quality products, respect for professionals, and ethical business practices in the textile industry | Textile Manufacturing | 🇧🇷 São Paulo | 1,970 | 1929 |
| 61 | [Maxion Structural Components](https://www.tamtam.ai/c/maxion-structural-components) (maxionsc.com)<br>Manufacturer of structural components for various vehicles, specializing in stamping and assembling products with a wide range of welding and surface treatment capabilities | Motor Vehicle Manufacturing | 🇧🇷 Cruzeiro | 1,960 | 1943 |
| 62 | [Toledo do Brasil](https://www.tamtam.ai/c/toledo-do-brasil) (toledobrasil.com)<br>A technology-driven organization that develops software, cloud platforms, and electronic labels, while also promoting employee engagement through music festivals, gaming tournaments, and cultural events | Appliances, Electrical, and Electronics Manufacturing | 🇧🇷 São Bernardo do Campo | 1,915 | 1956 |
| 63 | [LG Electronics Brasil](https://www.tamtam.ai/c/lg-electronics-brasil) (lg.com)<br>Leading consumer electronics manufacturer in Brazil with a wide range of products including TVs, audio and video equipment, smartphones, air conditioners, home appliances, and corporate solutions | Appliances, Electrical, and Electronics Manufacturing | 🇧🇷 São Paulo | 1,833 | 1996 |
| 64 | [Decathlon Brasil](https://www.tamtam.ai/c/decathlon-brasil) (decathlon.com.br)<br>Specialists in technical sports products Offering a wide range of personalized services and articles in 65 different sports, aiming for sustainable impact and excellence | Sporting Goods Manufacturing | 🇧🇷 São Paulo | 1,727 | 1976 |
| 65 | [Brazilian Center for Research in Energy and Materials (CNPEM)](https://www.tamtam.ai/c/brazilian-center-for-research-in-energy-and-materials-cnpem) (cnpem.br)<br>A research organization managing four national laboratories focused on synchrotron light, biotechnology, bioenergy, and nanotechnology, offering facilities to academia and industry worldwide | Research Services | 🇧🇷 Campinas | 1,686 | 1997 |
| 66 | [Villares Metals](https://www.tamtam.ai/c/villares-metals) (villaresmetals.com.br)<br>With over 75 years of history, the company is a global leader in developing high-quality special steels and alloys for various industries worldwide | Mining | 🇧🇷 Sumaré | 1,664 | 1944 |
| 67 | [Luizalabs](https://www.tamtam.ai/c/luizalabs) (luizalabs.com)<br>Using technology to provide a unique customer experience, this organization focuses on innovating and digitalizing the Brazilian retail sector through agile methodologies | Retail | 🇧🇷 São Paulo | 1,630 | 2014 |
| 68 | [CPQD](https://www.tamtam.ai/c/cpqd) (cpqd.com.br)<br>A leading innovator in information and communication technologies, specializing in solutions for various industries, digital transformation, IoT, AI, and more | IT Services and IT Consulting | 🇧🇷 Campinas | 1,577 | 1976 |
| 69 | [Myralis](https://www.tamtam.ai/c/myralis) (myralis.com.br)<br>A forward-looking pharmaceutical company focused on pioneering, excellence, and technology to deliver innovative medications nationwide through a strong production and distribution network | Pharmaceutical Manufacturing | 🇧🇷 Valinhos | 1,506 |  |
| 70 | [Mottu](https://www.tamtam.ai/c/mottu) (mottu.com.br)<br>Top startup in Brazil offering motorbike rentals for delivering goods, providing full support and maintenance, powered by proprietary technology for a seamless customer experience | Software Development | 🇧🇷 São Paulo | 1,470 | 2019 |
| 71 | [ICL América do Sul](https://www.tamtam.ai/c/icl-america-do-sul) (icl-growingsolutions.com)<br>Leading global provider of innovative and sustainable solutions in plant and animal nutrition, as well as raw materials for the fertilizer industry, impacting food production and environmental protection | Farming | 🇧🇷 São Paulo | 1,450 |  |
| 72 | [Denso Brasil](https://www.tamtam.ai/c/denso-brasil) (denso.com)<br>A global leader in technological innovation providing systems and components for major automotive manufacturers worldwide Committed to continuous improvement, excellence, and innovation | Motor Vehicle Parts Manufacturing | 🇧🇷 Santa Bárbara d'Oeste | 1,449 | 1980 |
| 73 | [Faculdade São Leopoldo Mandic](https://www.tamtam.ai/c/faculdade-sao-leopoldo-mandic) (slmandic.edu.br)<br>Leader in dental and medical education with top ranking by MEC Offer innovative education to enhance social development in Brazil across multiple locations | Higher Education | 🇧🇷 Campinas | 1,423 | 1978 |
| 74 | [AME](https://www.tamtam.ai/c/ame-sao-paulo) (linktr.ee)<br>A non-profit organization working for over 30 years to promote social inclusion for individuals facing barriers due to disabilities Utilizing technology for independence | Civic and Social Organizations | 🇧🇷 São Paulo | 1,400 | 1990 |
| 75 | [USCS - Universidade Municipal de São Caetano do Sul](https://www.tamtam.ai/c/uscs-universidade-municipal-de-sao-caetano-do-sul) (uscs.edu.br)<br>A municipal higher education institution in São Caetano do Sul, with diverse academic programs and full autonomy in academics and administration | Higher Education | 🇧🇷 São Caetano do Sul | 1,399 | 1968 |
| 76 | [GWM Brasil](https://www.tamtam.ai/c/gwm-brasil) (gwmmotors.com.br)<br>Investing in Brazilian automotive manufacturing, producing hybrid and electric vehicles for export across Latin America, and leading in SUVs and pickup trucks. | Motor Vehicle Manufacturing | 🇧🇷 São Paulo | 1,382 | 2021 |
| 77 | [Dedini](https://www.tamtam.ai/c/dedini) (dedini.com.br)<br>Manufacturer of capital goods, including a wide range of equipment for various industrial sectors, specializing in the global sugar and ethanol market | Industrial Machinery Manufacturing | 🇧🇷 Piracicaba | 1,347 | 1920 |
| 78 | [Packing Group](https://www.tamtam.ai/c/packing-group) (packinggroup.com.br)<br>Leader in flexible plastic packaging in Latin America, focusing on innovation and sustainability with Nanolayer technology, circular economy model, and sustainable resin products | Plastics Manufacturing | 🇧🇷 Valinhos | 1,333 | 1986 |
| 79 | [Grupo BBF](https://www.tamtam.ai/c/grupo-bbf) (linktr.ee)<br>A Brazilian company founded in 2008 to change the energy matrix in the North region, creating jobs, generating income, and reducing electricity costs with clean energy from palm oil | Renewable Energy Power Generation | 🇧🇷 São Paulo | 1,321 | 2008 |
| 80 | [AUNDE Brasil S.A.](https://www.tamtam.ai/c/aunde-brasil-s-a) (aunde.com.br)<br>For over 40 years, the company focuses on innovation and customer satisfaction, providing high-quality materials for vehicle interiors while prioritizing environmental conservation and occupational health | Textile Manufacturing | 🇧🇷 Poá | 1,314 |  |
| 81 | [&co. Cosméticos](https://www.tamtam.ai/c/and-co-cosmeticos) (andco.ind.br)<br>Specialized cosmetic industry with over 10 years of experience, offering personalized solutions for developing and manufacturing cosmetic products under private label, customization, or cobranding formats | Personal Care Product Manufacturing | 🇧🇷 Leme | 1,308 |  |
| 82 | [Unipac](https://www.tamtam.ai/c/unipac) (unipac.com.br)<br>A leading polymer transformation industry with innovative processes, high-performance products, digital services for various markets, and sustainable strategies Part of a global conglomerate | Plastics Manufacturing | 🇧🇷 Pompéia | 1,248 | 1976 |
| 83 | [Universidade Metodista de São Paulo](https://www.tamtam.ai/c/universidade-metodista-de-sao-paulo) (metodista.br)<br>A traditional higher education institution offering undergraduate, postgraduate, and short-term courses focusing on communication and information, with recognition for excellence in distance education | Higher Education | 🇧🇷 São Bernardo do Campo | 1,230 | 1938 |
| 84 | [IDEXX](https://www.tamtam.ai/c/idexx) (idexx.com.br)<br>Leader in innovation for pet healthcare, providing veterinary diagnostics, information, and services worldwide to improve animal health and well-being Also serving livestock and water safety industries | Biotechnology Research | 🇧🇷 São Paulo | 1,191 | 1983 |
| 85 | [CHRIS CINTOS DE SEGURANÇA](https://www.tamtam.ai/c/chris-cintos-de-seguranca) (chriscintos.com.br)<br>Established in 1952, this Latin American leader in safety belt manufacturing is committed to producing high-quality, competitively-priced products for customer satisfaction | Motor Vehicle Parts Manufacturing | 🇧🇷 São Paulo | 1,144 | 1952 |
| 86 | [Kromberg & Schubert do Brasil](https://www.tamtam.ai/c/kromberg-and-schubert-do-brasil) (kromberg-schubert.com)<br>Global supplier of electrical systems, cables, and plastic components with a focus on innovation, customer needs, and employee development. | Motor Vehicle Manufacturing | 🇧🇷 Itatiba | 1,144 | 1902 |
| 87 | [Nitro](https://www.tamtam.ai/c/nitro) (nitro.com.br)<br>Global producer of chemical specialties for diverse industrial sectors and agricultural inputs, focusing on technological competence and safety standards for client solutions. | Chemical Manufacturing | 🇧🇷 São Paulo | 1,135 | 1935 |
| 88 | [Faculdade Israelita Albert Einstein](https://www.tamtam.ai/c/faculdade-israelita-albert-einstein) (ensino.einstein.br)<br>A non-profit organization providing healthcare, education, research, and social projects, including a variety of educational programs in healthcare | Higher Education | 🇧🇷 São Paulo | 1,132 | 1989 |
| 89 | [Amway do Brasil Ltda](https://www.tamtam.ai/c/amway-do-brasil-ltda) (amway.com.br)<br>Manufacturing world-renowned brands, we empower individuals worldwide to improve their lifestyle through entrepreneurship, offering opportunities for extra income | Manufacturing | 🇧🇷 São Paulo | 1,125 | 1991 |
| 90 | [Gertec](https://www.tamtam.ai/c/gertec) (gertec.com.br)<br>With 24 years of experience, the company specializes in manufacturing a wide range of automated products for various industries worldwide | IT Services and IT Consulting | 🇧🇷 São Paulo | 1,108 | 1989 |
| 91 | [CTG Brasil](https://www.tamtam.ai/c/ctg-brasil) (ctgbr.com.br)<br>Develops world with large-scale clean energy. Investments in hydroelectric, wind, and solar power plants in Brazil. Part of a global clean energy leader. | Utilities | 🇧🇷 São Paulo | 1,081 | 2013 |
| 92 | [Hospital de Cancer de Barretos Fundação PIO XII](https://www.tamtam.ai/c/hospital-de-cancer-de-barretos-fundacao-pio-xii) (hospitaldeamor.com.br)<br>The organization provides specialized cancer treatment services for low-income patients, founded in 1967 and continually expanding with community and governmental support | Wellness and Fitness Services | 🇧🇷 Barretos | 1,062 | 1962 |
| 93 | [Caldic LATAM](https://www.tamtam.ai/c/caldic-latam)<br>Global provider of innovative and sustainable solutions for the food, pharmaceutical, personal care, and industrial markets, focused on customer needs with expertise in research and development | Chemical Manufacturing | 🇧🇷 São Paulo | 1,055 |  |
| 94 | [OBER S/A](https://www.tamtam.ai/c/ober-s-a) (ober.com.br)<br>A Brazilian company with over 50 years of experience in the production of nonwovens, fabrics, and converted products, focusing on quality, service, and innovation | Textile Manufacturing | 🇧🇷 Nova Odessa | 1,041 | 1962 |
| 95 | [MSD Saúde Animal](https://www.tamtam.ai/c/msd-saude-animal) (msd-saude-animal.com.br)<br>Global animal health unit providing veterinarians, farmers, pet owners, and governments with a wide range of veterinary pharmaceuticals, vaccines, and health management solutions | Veterinary Services | 🇧🇷 São Paulo | 1,034 | 1986 |
| 96 | [Beontag](https://www.tamtam.ai/c/beontag) (beontag.com)<br>Global leader providing IoT solutions and graphic materials to drive seamless communication in multiple industries, with a focus on sustainability and diversity | Packaging and Containers Manufacturing | 🇧🇷 São Paulo | 1,030 |  |
| 97 | [ARTEB](https://www.tamtam.ai/c/arteb) (arteb.com.br)<br>A leading automotive lighting manufacturer with over 85 years of experience, specializing in headlights, tail lights, and Full LED development for major Brazilian automakers | Motor Vehicle Parts Manufacturing | 🇧🇷 São Bernardo do Campo | 1,011 | 1934 |
| 98 | [Karina Plásticos](https://www.tamtam.ai/c/karina-plasticos) (karina.com.br)<br>A leading specialist in producing compounds, focusing on PVC, Polyolefin Specialties, and Masterbatch for national and international clients for nearly 40 years | Plastics Manufacturing | 🇧🇷 Guarulhos | 1,004 | 1979 |
| 99 | [Unigel](https://www.tamtam.ai/c/unigel) (unigel.com.br)<br>A conglomerate with over four decades of experience in the petrochemical and plastic sector, operating nationally and internationally in four business areas | Chemical Manufacturing | 🇧🇷 São Paulo | 1,004 | 1966 |
| 100 | [SiDi](https://www.tamtam.ai/c/sidi) (sidi.org.br)<br>An R&D institute in Brazil creating transformative projects and solving problems, impacting millions through innovation and making the future happen. | Retail | 🇧🇷 Campinas | 996 | 2004 |

## How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 13, 2026.

## More company lists in São Paulo State

- [The largest companies in São Paulo State](https://www.tamtam.ai/l/largest-companies-sao-paulo-state) (6,967)
- [Manufacturers in São Paulo State](https://www.tamtam.ai/l/manufacturers-sao-paulo-state) (972)
- [Multinational companies in São Paulo State](https://www.tamtam.ai/l/multinational-companies-sao-paulo-state) (757)
- [Retail chains in São Paulo State](https://www.tamtam.ai/l/retail-chains-sao-paulo-state) (741)
- [Financial Services companies in São Paulo State](https://www.tamtam.ai/l/financial-services-companies-sao-paulo-state) (557)
- [Financial services firms in São Paulo State](https://www.tamtam.ai/l/financial-services-firms-sao-paulo-state) (468)
- [Education providers in São Paulo State](https://www.tamtam.ai/l/education-companies-sao-paulo-state-brazil) (466)
- [Critical infrastructure operators in São Paulo State](https://www.tamtam.ai/l/critical-infrastructure-operators-sao-paulo-state) (437)
- [Companies with a mobile app in São Paulo State](https://www.tamtam.ai/l/companies-with-mobile-app-sao-paulo-state) (415)
- [Healthcare providers in São Paulo State](https://www.tamtam.ai/l/healthcare-providers-sao-paulo-state) (390)
- [Retail companies in São Paulo State](https://www.tamtam.ai/l/retail-companies-sao-paulo-state) (390)
- [E-commerce companies in São Paulo State](https://www.tamtam.ai/l/ecommerce-companies-sao-paulo-state) (369)
- [IT Services and IT Consulting companies in São Paulo State](https://www.tamtam.ai/l/it-services-and-it-consulting-companies-sao-paulo-state) (350)
- [Corporate groups and holding companies in São Paulo State](https://www.tamtam.ai/l/holding-companies-sao-paulo-state) (318)
- [Food and beverage companies in São Paulo State](https://www.tamtam.ai/l/food-and-beverage-companies-sao-paulo-state) (267)
- [Professional services firms in São Paulo State](https://www.tamtam.ai/l/professional-services-firms-sao-paulo-state) (265)
- [Hardware manufacturers in São Paulo State](https://www.tamtam.ai/l/hardware-companies-sao-paulo-state) (260)
- [Logistics companies in São Paulo State](https://www.tamtam.ai/l/logistics-companies-sao-paulo-state) (247)
- [Hospitals and Health Care companies in São Paulo State](https://www.tamtam.ai/l/hospitals-and-health-care-companies-sao-paulo-state) (242)
- [Distributors and wholesalers in São Paulo State](https://www.tamtam.ai/l/distributors-and-wholesalers-sao-paulo-state) (219)
- [Fintech companies in São Paulo State](https://www.tamtam.ai/l/fintech-companies-sao-paulo-state) (207)
- [Consumer goods companies in São Paulo State](https://www.tamtam.ai/l/consumer-goods-companies-sao-paulo-state) (199)
- [Franchise networks in São Paulo State](https://www.tamtam.ai/l/franchise-networks-sao-paulo-state) (199)
- [Food and Beverage Services companies in São Paulo State](https://www.tamtam.ai/l/food-and-beverage-services-companies-sao-paulo-state) (198)

## The same list elsewhere in Brazil

- [Companies with in-house R&D in Brazil](https://www.tamtam.ai/l/r-and-d-companies-brazil) (755)
- [Companies with in-house R&D in Minas Gerais](https://www.tamtam.ai/l/r-and-d-companies-minas-gerais) (62)
- [Companies with in-house R&D in Paraná](https://www.tamtam.ai/l/r-and-d-companies-parana) (61)
- [Companies with in-house R&D in Santa Catarina](https://www.tamtam.ai/l/r-and-d-companies-santa-catarina) (58)
- [Companies with in-house R&D in Rio de Janeiro State](https://www.tamtam.ai/l/r-and-d-companies-rio-de-janeiro-state) (43)
- [Companies with in-house R&D in Rio Grande do Sul](https://www.tamtam.ai/l/r-and-d-companies-rio-grande-do-sul) (42)
- [Companies with in-house R&D in São Paulo](https://www.tamtam.ai/l/r-and-d-companies-sao-paulo) (145)
- [Companies with in-house R&D in Rio de Janeiro](https://www.tamtam.ai/l/r-and-d-companies-rio-de-janeiro) (32)

## The same list elsewhere

- [Companies with in-house R&D in the world](https://www.tamtam.ai/l/r-and-d-companies-in-the-world) (34,334)
- [Companies with in-house R&D in Latin America](https://www.tamtam.ai/l/r-and-d-companies-in-latin-america) (1,191)

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Source: https://www.tamtam.ai/l/r-and-d-companies-sao-paulo-state