# Top 30 companies with in-house R&D in São Paulo

Tamtam tracks 145 companies with in-house R&D headquartered in São Paulo. This list ranks the 30 largest by number of employees on LinkedIn, led by JBS, Natura and Einstein Hospital Israelita. Their median headcount is 7,519. Half of them were founded in 1953 or later.

The companies with in-house R&D in São Paulo are mostly large Brazilian groups. They span diverse sectors such as food production with JBS, personal care with Natura, and pulp and paper with Suzano and Klabin. The list also includes major healthcare providers like Einstein Hospital Israelita and Sírio-Libanês, as well as technology firms such as TOTVS, which provides business digitalization solutions.

A notable characteristic of these companies is their strong representation in the healthcare sector, with multiple large hospitals and healthcare networks. Another pattern is the significant presence of companies founded in the mid-20th century, indicating established industrial development in the region.

🇧🇷 São Paulo · 30 companies · Updated Nov 13, 2026

| # | Company | Industry | Headquarters | Employees | Founded |
|---|---|---|---|---|---|
| 1 | [JBS](https://www.tamtam.ai/c/jbs) (jbs.com.br)<br>Global leader in protein-based food production with diverse product portfolio spanning multiple countries and industries, committed to feeding the world with excellence and innovation | Food and Beverage Manufacturing | 🇧🇷 São Paulo | 88,182 | 1953 |
| 2 | [Natura](https://www.tamtam.ai/c/natura) (natura.com.br)<br>A Brazilian multinational in cosmetics and personal care known for sustainable practices, direct sales, cruelty-free and vegan products, and Amazon biodiversity protection | Personal Care Product Manufacturing | 🇧🇷 São Paulo | 47,988 | 1969 |
| 3 | [Einstein Hospital Israelita](https://www.tamtam.ai/c/einstein-hospital-israelita) (einstein.br)<br>A leading healthcare institution offering cutting-edge treatments, compassionate care, social responsibility initiatives, and education and research programs for the community | Hospitals and Health Care | 🇧🇷 São Paulo | 40,979 |  |
| 4 | [Dasa](https://www.tamtam.ai/c/dasa) (dasa.com.br)<br>The company is the largest integrated healthcare network in Brazil, focusing on preventive, predictive, and personalized healthcare with a wide range of services and innovative solutions | Hospitals and Health Care | 🇧🇷 São Paulo | 32,801 | 1999 |
| 5 | [Suzano](https://www.tamtam.ai/c/suzano) (suzano.com.br)<br>Global leader in sustainable use of natural resources, producing eucalyptus pulp and paper, with innovative solutions promoting renewable bio-based materials worldwide | Paper and Forest Product Manufacturing | 🇧🇷 São Paulo | 23,529 | 1924 |
| 6 | [Sírio-Libanês](https://www.tamtam.ai/c/sirio-libanes) (hospitalsiriolibanes.org.br)<br>A renowned healthcare institution with philanthropic roots, offering top-notch medical services, cutting-edge technology, education, research, and social responsibility initiatives for 100 years | Hospitals and Health Care | 🇧🇷 São Paulo | 19,137 | 1921 |
| 7 | [TOTVS](https://www.tamtam.ai/c/totvs) (totvs.com)<br>A leading technology company in Brazil, providing comprehensive solutions for business digitalization through ERP, financial services, and business performance solutions | Software Development | 🇧🇷 São Paulo | 17,675 |  |
| 8 | [Klabin](https://www.tamtam.ai/c/klabin) (klabin.com.br)<br>A leading producer of renewable and biodegradable paper, cardboard, packaging, and wood products, focused on developing smart solutions for customer needs | Paper and Forest Product Manufacturing | 🇧🇷 São Paulo | 16,499 | 1899 |
| 9 | [Braskem](https://www.tamtam.ai/c/braskem) (braskem.com)<br>Global company dedicated to sustainable solutions in chemicals and plastics, driving the Circular Economy with innovation and a diverse product portfolio for various industries worldwide | Plastics Manufacturing | 🇧🇷 São Paulo | 10,586 |  |
| 10 | [Votorantim Cimentos](https://www.tamtam.ai/c/votorantim-cimentos) (votorantimcimentos.com.br)<br>A leading international provider of construction materials, with a diverse portfolio including cement, concrete, and aggregates Also active in agricultural inputs and waste management | Construction | 🇧🇷 São Paulo | 9,998 | 1936 |
| 11 | [Senai São Paulo](https://www.tamtam.ai/c/senai-sao-paulo) (sp.senai.br)<br>Industry-managed institution in Brazil and Latin America specializing in professional training for the industrial sector since 1942, with over 85 schools and training centers | Professional Training and Coaching | 🇧🇷 São Paulo | 9,989 | 1942 |
| 12 | [Universidade Estadual Paulista Júlio de Mesquita Filho](https://www.tamtam.ai/c/universidade-estadual-paulista-julio-de-mesquita-filho) (www2.unesp.br)<br>A leading Brazilian university with a multicampus structure offering quality education, research opportunities, and community services to students and society | Higher Education | 🇧🇷 São Paulo | 9,365 | 1976 |
| 13 | [CEJAM - Centro de Estudos e Pesquisas Dr. João Amorim - OFICIAL](https://www.tamtam.ai/c/cejam-centro-de-estudos-e-pesquisas-dr-joao-amorim-oficial) (cejam.org.br)<br>Non-profit institution supporting the Brazilian public health system with over 30 years of experience in primary care, specialized services, emergency care, and hospital management | Hospitals and Health Care | 🇧🇷 São Paulo | 8,271 | 1991 |
| 14 | [Hospital das Clínicas da Faculdade de Medicina da USP](https://www.tamtam.ai/c/hospital-das-clinicas-da-faculdade-de-medicina-da-usp) (hc.fm.usp.br)<br>A public institution affiliated with a medical school in São Paulo, dedicated to health public healthcare through education, research, assistance, and management | Hospitals and Health Care | 🇧🇷 São Paulo | 8,241 | 1944 |
| 15 | [União Química Farmacêutica Nacional](https://www.tamtam.ai/c/uniao-quimica-farmaceutica-nacional) (uniaoquimica.com.br)<br>A pharmaceutical company in Brazil with a strong focus on innovation, social responsibility, and environmental sustainability, offering various benefits to employees | Pharmaceutical Manufacturing | 🇧🇷 São Paulo | 7,519 | 1936 |
| 16 | [BP - A Beneficência Portuguesa de São Paulo](https://www.tamtam.ai/c/bp-a-beneficencia-portuguesa-de-sao-paulo) (bp.org.br)<br>The organization prioritizes valuing and celebrating life through research, understanding, and technology, with a focus on continuous evolution and respect for all | Hospitals and Health Care | 🇧🇷 São Paulo | 6,759 | 1859 |
| 17 | [A.C.Camargo Cancer Center](https://www.tamtam.ai/c/a-c-camargo-cancer-center) (accamargo.org.br)<br>A specialized center focused on cancer diagnosis, treatment, education, and research with highly specialized healthcare professionals working together in one place | Hospitals and Health Care | 🇧🇷 São Paulo | 6,452 | 1953 |
| 18 | [Uninove - Universidade Nove de Julho](https://www.tamtam.ai/c/uninove-universidade-nove-de-julho) (uninove.br)<br>A leading educational institution in São Paulo offering a wide range of undergraduate, postgraduate, and research programs through innovative teaching methods and state-of-the-art facilities | Higher Education | 🇧🇷 São Paulo | 6,396 | 1954 |
| 19 | [Hypera](https://www.tamtam.ai/c/hypera) (hypera.com.br)<br>Leading Brazilian pharmaceutical company across various segments including consumer health, prescription products, dermocosmetics, and generics, offering high-quality, safe products through continuous innovation. | Pharmaceutical Manufacturing | 🇧🇷 São Paulo | 6,251 | 2001 |
| 20 | [Hospital Alemão Oswaldo Cruz](https://www.tamtam.ai/c/hospital-alemao-oswaldo-cruz) (hospitaloswaldocruz.org.br)<br>A leading hospital in Latin America providing comprehensive healthcare services, high complexity treatments, and innovative care models focused on patient-centered approach | Hospitals and Health Care | 🇧🇷 São Paulo | 6,204 | 1897 |
| 21 | [Dexco](https://www.tamtam.ai/c/dexco) (dex.co)<br>We provide aesthetic and functional solutions through our brands, focusing on environmental and social issues, with a strong presence in the Brazilian market | Construction | 🇧🇷 São Paulo | 6,195 |  |
| 22 | [Saint-Gobain Brasil](https://www.tamtam.ai/c/saint-gobain-brasil) (saint-gobain.com.br)<br>A global leader in sustainable construction materials and solutions, operating in 66 countries with a focus on well-being, performance, and sustainability | Wholesale Building Materials | 🇧🇷 São Paulo | 5,593 | 1937 |
| 23 | [Universidade Presbiteriana Mackenzie](https://www.tamtam.ai/c/universidade-presbiteriana-mackenzie) (mackenzie.br)<br>Educates individuals for citizenship, fosters personal and societal development through teaching, research, extension, cultural, sports, social, and spiritual activities, grounded in reformed Christian faith. | Higher Education | 🇧🇷 São Paulo | 5,286 | 1870 |
| 24 | [LIBBS FARMACÊUTICA LTDA](https://www.tamtam.ai/c/libbs-farmaceutica-ltda) (libbs.com.br)<br>A national pharmaceutical company focused on producing healthcare solutions with a strong commitment to research, development, innovation, and social initiatives | Pharmaceutical Manufacturing | 🇧🇷 São Paulo | 5,236 | 1958 |
| 25 | [QuintoAndar](https://www.tamtam.ai/c/quintoandar) (carreiras.quintoandar.com.br)<br>Largest Latin America real estate ecosystem offering diverse brands and innovative technologies to enhance and support all housing journey stages. | Software Development | 🇧🇷 São Paulo | 5,039 | 2012 |
| 26 | [Biolab & Co](https://www.tamtam.ai/c/biolab-and-co) (biolabfarma.com.br)<br>Pharmaceutical innovator in Brazil, offering over 170 products for various health needs Leading in Cardiology, Dermatology, Gynecology, and more | Pharmaceutical Manufacturing | 🇧🇷 São Paulo | 5,014 | 1997 |
| 27 | [Whirlpool Latin America](https://www.tamtam.ai/c/whirlpool-latin-america) (whirlpool.com.br)<br>Leading Latin American market in home appliances with popular brands, manufacturing plants, extensive R&D labs, and recognition for innovation and sustainability efforts Visit website for more information | Consumer Goods | 🇧🇷 São Paulo | 4,104 |  |
| 28 | [Instituto do Câncer do Estado de São Paulo - ICESP](https://www.tamtam.ai/c/instituto-do-cancer-do-estado-de-sao-paulo-icesp) (icesp.org.br)<br>A leading oncology center in Latin America, focused on providing high-quality care, education, and research in the public health system | Hospitals and Health Care | 🇧🇷 São Paulo | 4,018 | 2008 |
| 29 | [UTC Engenharia](https://www.tamtam.ai/c/utc-engenharia) (utc.com.br)<br>An industry leader in various sectors including oil & gas, petrochemicals, power generation, and steel production with over 1,000 successful contracts | Construction | 🇧🇷 São Paulo | 3,618 |  |
| 30 | [Ajinomoto do Brasil](https://www.tamtam.ai/c/ajinomoto-do-brasil) (ajinomoto.com.br)<br>Specializing in creating products for various industries using umami flavor, with a focus on food, cosmetics, pharmaceuticals, animal nutrition, and agriculture | Food and Beverage Services | 🇧🇷 São Paulo | 3,618 |  |

## How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 13, 2026.

## More company lists in São Paulo

- [The largest companies in São Paulo](https://www.tamtam.ai/l/largest-companies-sao-paulo) (3,842)
- [Multinational companies in São Paulo](https://www.tamtam.ai/l/multinational-companies-sao-paulo) (472)
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- [Franchise networks in São Paulo](https://www.tamtam.ai/l/franchise-networks-sao-paulo) (114)
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## The same list elsewhere in Brazil

- [Companies with in-house R&D in Brazil](https://www.tamtam.ai/l/r-and-d-companies-brazil) (755)
- [Companies with in-house R&D in São Paulo State](https://www.tamtam.ai/l/r-and-d-companies-sao-paulo-state) (370)
- [Companies with in-house R&D in Minas Gerais](https://www.tamtam.ai/l/r-and-d-companies-minas-gerais) (62)
- [Companies with in-house R&D in Paraná](https://www.tamtam.ai/l/r-and-d-companies-parana) (61)
- [Companies with in-house R&D in Santa Catarina](https://www.tamtam.ai/l/r-and-d-companies-santa-catarina) (58)
- [Companies with in-house R&D in Rio de Janeiro State](https://www.tamtam.ai/l/r-and-d-companies-rio-de-janeiro-state) (43)
- [Companies with in-house R&D in Rio Grande do Sul](https://www.tamtam.ai/l/r-and-d-companies-rio-grande-do-sul) (42)
- [Companies with in-house R&D in Rio de Janeiro](https://www.tamtam.ai/l/r-and-d-companies-rio-de-janeiro) (32)

## The same list elsewhere

- [Companies with in-house R&D in the world](https://www.tamtam.ai/l/r-and-d-companies-in-the-world) (34,334)
- [Companies with in-house R&D in Latin America](https://www.tamtam.ai/l/r-and-d-companies-in-latin-america) (1,191)

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Source: https://www.tamtam.ai/l/r-and-d-companies-sao-paulo