# The 100 largest companies with in-house R&D in Spain

Tamtam tracks 1,067 companies with in-house R&D headquartered in Spain. This list ranks the 100 largest by number of employees on LinkedIn, led by MITSUBISHI ELECTRIC, Santander and Telefónica. Their median headcount is 4,163. Half of them were founded in 1968 or later. The most common headquarters are Madrid (30), Barcelona (14) and Bilbao (4).

This list covers major companies with in-house R&D operations in Spain. It includes large, established firms such as Santander, a global bank, Telefónica, a telecommunications leader, and Inditex, a global clothing and home goods conglomerate. Other notable companies are Quirónsalud, a healthcare provider, and Iberdrola, specializing in renewable energy.

Many of the companies featured are headquartered in Madrid, indicating a concentration of large corporate R&D activity in the capital. The sectors represented are diverse, ranging from banking and telecommunications to retail, healthcare, and energy.

🇪🇸 Spain · 100 companies · Updated Nov 11, 2026

| # | Company | Industry | Headquarters | Employees | Founded |
|---|---|---|---|---|---|
| 1 | [MITSUBISHI ELECTRIC](https://www.tamtam.ai/c/mitsubishi-electric) (mitsubishielectric.com)<br>A leader in electric and electronic equipment manufacturing, focusing on Energy Systems, Industrial Automation, Information Systems, Electronic Devices, and Home Appliances | Appliances, Electrical, and Electronics Manufacturing | 🇪🇸 Chiyoda-ku | 146,000 | 1921 |
| 2 | [Santander](https://www.tamtam.ai/c/santander) (santander.com)<br>Leading global bank offering retail, corporate, investment banking, wealth management, insurance, and payment services to diverse clients worldwide. | Banking | 🇪🇸 Boadilla del Monte | 129,701 |  |
| 3 | [Telefónica](https://www.tamtam.ai/c/telefonica) (telefonica.com)<br>Leading global telecommunications company providing advanced infrastructure, innovative digital and data services, focusing on secure, cutting-edge technology and social impact. | Telecommunications | 🇪🇸 Madrid | 121,569 |  |
| 4 | [Inditex](https://www.tamtam.ai/c/inditex) (inditexpeople.com)<br>A global conglomerate of clothing brands and home goods, with online and physical presence in 213 markets, led by a dedicated team focused on continuous improvement | Retail | 🇪🇸 Arteixo | 73,716 | 1974 |
| 5 | [Quirónsalud](https://www.tamtam.ai/c/quironsalud) (quironsalud.com)<br>Leader in healthcare in Spain and Europe with over 50,000 professionals and 59 hospitals, focusing on medical research, education, and cutting-edge technology | Wellness and Fitness Services | 🇪🇸 Madrid | 50,000 | 1893 |
| 6 | [Iberdrola](https://www.tamtam.ai/c/iberdrola) (iberdrola.com)<br>A global leader in renewable energy and electricity, focusing on sustainable and efficient services for millions worldwide with investments in clean energy and digital transformation | Electric Power Generation | 🇪🇸 Bilbao | 45,000 | 1901 |
| 7 | [Indra Group](https://www.tamtam.ai/c/indra-group) (indragroup.com)<br>Leading multinational providing defense, space, air traffic management, and mobility solutions alongside information technology services, artificial intelligence, cybersecurity, and advanced digital transformation projects. | Defense and Space Manufacturing | 🇪🇸 Madrid | 39,308 |  |
| 8 | [ACCIONA](https://www.tamtam.ai/c/acciona) (acciona.com)<br>The company specializes in developing regenerative infrastructure with a focus on sustainability, leading the transition to a low-carbon economy with a positive impact on people and the planet | Utilities | 🇪🇸 Madrid | 33,828 |  |
| 9 | [NTT DATA Europe & Latam](https://www.tamtam.ai/c/ntt-data-europe-and-latam) (nttdata.com)<br>Global IT services provider transforming clients through consulting, solutions, and managed services to enable a confident move into the digital future | IT Services and IT Consulting | 🇪🇸 Madrid | 31,932 |  |
| 10 | [repsol](https://www.tamtam.ai/c/repsol) (repsol.com)<br>A leading player in the oil and gas industry, involved in exploration, production, transformation, development, and marketing of efficient, sustainable energy solutions globally | Oil and Gas | 🇪🇸 Madrid | 26,030 |  |
| 11 | [Amadeus](https://www.tamtam.ai/c/amadeus) (amadeus.com)<br>A company revolutionizing the travel industry by inspiring innovation, partnerships, and responsibility, connecting the travel ecosystem and promoting social and environmental good | IT Services and IT Consulting | 🇪🇸 Madrid | 23,625 | 1987 |
| 12 | [Applus+](https://www.tamtam.ai/c/applus) (applus.com)<br>A global leader in testing, inspection, and certification services, providing innovative solutions for asset integrity, regulatory compliance, and environmental performance | Business Consulting and Services | 🇪🇸 Madrid | 20,046 |  |
| 13 | [Siemens Gamesa](https://www.tamtam.ai/c/siemens-gamesa) (siemensgamesa.com)<br>Global technology leader in renewable energy industry, specializing in wind turbine development, manufacturing, installation, and maintenance Driving energy transition towards sustainability | Renewable Energy Semiconductor Manufacturing | 🇪🇸 Zamudio | 19,821 | 2017 |
| 14 | [Gestamp](https://www.tamtam.ai/c/gestamp) (gestamp.com)<br>A multinational company specializing in designing and manufacturing advanced metal components for vehicle manufacturers worldwide, focusing on lighter, safer, and more environmentally friendly products | Motor Vehicle Manufacturing | 🇪🇸 Madrid | 17,667 | 1997 |
| 15 | [Grifols](https://www.tamtam.ai/c/grifols) (linktr.ee)<br>A global healthcare company specializing in plasma-derived medicines, transfusion medicine, and innovative healthcare solutions, committed to improving people's health worldwide | Pharmaceutical Manufacturing | 🇪🇸 Sant Cugat del Vallès | 14,329 | 1909 |
| 16 | [Universidad Complutense de Madrid](https://www.tamtam.ai/c/universidad-complutense-de-madrid) (ucm.es)<br>A public university in Madrid offering high-quality education, research opportunities, international collaborations, extensive library resources, diverse cultural activities, and sports facilities | Higher Education | 🇪🇸 Madrid | 14,024 | 1499 |
| 17 | [EVOLUTION MADRID SL.](https://www.tamtam.ai/c/evolution-birkirkara) (evolution.com)<br>A world-leader in innovative IT solutions for live casino streaming, processing millions of transactions globally with a market cap of over EUR 20B | IT Services and IT Consulting | 🇪🇸 Birkirkara | 14,000 | 2006 |
| 18 | [Universidad Autónoma de Madrid](https://www.tamtam.ai/c/universidad-autonoma-de-madrid) (uam.es)<br>Institution recognized for high-quality research, entrepreneurial capacity, teaching excellence, and social commitment. Actively promotes international exchange and training programs. | Higher Education | 🇪🇸 Madrid | 14,000 | 1968 |
| 19 | [Tecnicas Reunidas](https://www.tamtam.ai/c/tecnicas-reunidas) (tecnicasreunidas.es)<br>An international general contractor specializing in engineering and construction of industrial facilities in oil & gas, refining, power generation, infrastructures, and energy transition | Engineering Services | 🇪🇸 Madrid | 12,368 | 1960 |
| 20 | [Grupo Tragsa](https://www.tamtam.ai/c/grupo-tragsa) (tragsa.es)<br>Provides engineering, technical assistance, and execution of projects for public administrations in agriculture, environment, and rural development sectors. | Environmental Services | 🇪🇸 Madrid | 12,239 | 1977 |
| 21 | [Puig](https://www.tamtam.ai/c/puig) (puig.com)<br>A family company that houses Love Brands in beauty and fashion, creating engaging storytelling and honoring ESG commitments for a better world | Personal Care Product Manufacturing | 🇪🇸 Hospitalet de Llobregat | 11,873 |  |
| 22 | [Elecnor Group](https://www.tamtam.ai/c/elecnor-group) (grupoelecnor.com)<br>Global corporation specializing in engineering, construction, sustainable projects, infrastructure investments, renewable energy, asset management, and energy transmission across 50 countries. | Construction | 🇪🇸 Madrid | 10,383 | 1958 |
| 23 | [Universitat de Barcelona](https://www.tamtam.ai/c/universitat-de-barcelona) (web.ub.edu)<br>Leading Spanish university with extensive research departments, numerous projects, and collaborations with national and European institutions and businesses. | Research Services | 🇪🇸 Barcelona | 10,368 | 1450 |
| 24 | [CAF (Construcciones y Auxiliar de Ferrocarriles)](https://www.tamtam.ai/c/caf-construcciones-y-auxiliar-de-ferrocarriles) (cafmobility.com)<br>Designs and manufactures advanced sustainable transportation systems including accessible rail vehicles and zero-emission urban buses worldwide. | Motor Vehicle Manufacturing | 🇪🇸 Beasain | 10,000 | 1917 |
| 25 | [Universitat Autònoma de Barcelona](https://www.tamtam.ai/c/universitat-autonoma-de-barcelona) (uab.cat)<br>The organization is a pioneering, research-focused university in Barcelona, known for its diversity, sustainability, and campus culture, offering unique experiences | Higher Education | 🇪🇸 Bellaterra (Cerdanyola del Vallès) | 8,649 | 1968 |
| 26 | [NINGUNO](https://www.tamtam.ai/c/ninguno) (siadde.es)<br>A technology company with over 20 years of experience providing comprehensive solutions in security systems, telecommunications, software development, and more for various industries | Telecommunications | 🇪🇸 Madrid | 8,620 | 2026 |
| 27 | [SEAT S.A.](https://www.tamtam.ai/c/seat-s-a) (seat.com)<br>A multinational company in Spain, part of the Volkswagen Group, designing, manufacturing, and selling cars under SEAT and CUPRA brands globally Employing 15,000 professionals | Motor Vehicle Manufacturing | 🇪🇸 Martorell | 8,030 | 1950 |
| 28 | [Antolin](https://www.tamtam.ai/c/antolin) (antolin.com)<br>Design, development, and manufacture of modular automotive interior components including overhead, door, lighting, cockpits, and electronic systems worldwide. | Motor Vehicle Manufacturing | 🇪🇸 Burgos | 7,947 | 1950 |
| 29 | [Institut Català de la Salut](https://www.tamtam.ai/c/institut-catala-de-la-salut) (ics.gencat.cat)<br>The company provides healthcare services from pregnancy to old age, with a wide territorial coverage and a strong emphasis on education, research, and innovation | Hospitals and Health Care | 🇪🇸 Barcelona | 7,936 |  |
| 30 | [Roca Group](https://www.tamtam.ai/c/roca-group) (rocagroup.com)<br>Global enterprise manufacturing and selling bathroom solutions across 170 countries with 81 production plants to improve quality of life through sustainable development. | Manufacturing | 🇪🇸 Barcelona | 7,451 | 1917 |
| 31 | [Universidad de Granada](https://www.tamtam.ai/c/universidad-de-granada) (ugr.es)<br>The company is a university known for high-quality research, with 346 research groups, 165 projects, and partnerships with businesses and international organizations | Higher Education | 🇪🇸 Granada | 7,376 | 1531 |
| 32 | [Eroski](https://www.tamtam.ai/c/eroski) (corporativo.eroski.es)<br>A multinational socio-business group with over 50,000 employees, specializing in retail sales through a vast network of supermarkets and hypermarkets | Retail | 🇪🇸 Elorrio | 7,340 | 1969 |
| 33 | [Insud Pharma](https://www.tamtam.ai/c/insud-pharma) (insudpharma.com)<br>Specialized pharmaceutical company with global presence, offering APIs, finished dosage forms, branded medicines, and biotech solutions for human and animal health. | Pharmaceutical Manufacturing | 🇪🇸 Madrid | 7,035 | 1977 |
| 34 | [Werfen](https://www.tamtam.ai/c/werfen) (werfen.com)<br>A global innovator in specialized diagnostics, offering Hemostasis, Acute Care Diagnostics, Transfusion, Autoimmunity, and Transplant solutions through OEM manufacturing and distribution | Medical Equipment Manufacturing | 🇪🇸 L'Hospitalet de Llobregat | 6,858 |  |
| 35 | [Tragsatec](https://www.tamtam.ai/c/tragsatec) (tragsa.es)<br>Tragsatec offers engineering and technical assistance in various fields including environmental, agricultural, fisheries, infrastructures, and information technologies, focusing on innovation and quality services | Environmental Services | 🇪🇸 | 6,560 | 1989 |
| 36 | [Universidad Politécnica de Madrid](https://www.tamtam.ai/c/universidad-politecnica-de-madrid) (upm.es)<br>Educates students in architecture, engineering, sport, and fashion design, conducts research, and secures significant R&D funding from European and national programs. | Higher Education | 🇪🇸 Madrid | 6,447 | 1971 |
| 37 | [Hospital Clínic de Barcelona](https://www.tamtam.ai/c/hospital-clinic-de-barcelona) (clinicbarcelona.org)<br>A leading public university hospital in Spain, offering quality healthcare, cutting-edge research, and professional training with a focus on humanized medicine | Hospitals and Health Care | 🇪🇸 Barcelona | 6,159 | 1906 |
| 38 | [INECO](https://www.tamtam.ai/c/ineco) (ineco.com)<br>A leading engineering and consulting firm in sustainable mobility and digital transformation, with a global presence and a focus on innovation | Civil Engineering | 🇪🇸 Madrid | 5,743 | 1968 |
| 39 | [IDOM Consulting, Engineering, Architecture](https://www.tamtam.ai/c/idom-consulting-engineering-architecture) (idom.com)<br>A multinational consulting, engineering, and architecture firm offering personalized client services, delivering independent, impartial global projects with a diverse, engaged workforce | Engineering Services | 🇪🇸 Bilbao | 5,424 | 1957 |
| 40 | [Samu](https://www.tamtam.ai/c/samu-seville) (samu.es)<br>A pioneering group in Spain with 40 years of healthcare, social action, and emergency experience, employing 2,000 professionals worldwide | Wellness and Fitness Services | 🇪🇸 Seville | 5,416 | 1981 |
| 41 | [Universitat Politècnica de Catalunya](https://www.tamtam.ai/c/universitat-politecnica-de-catalunya) (upc.edu)<br>Public institution specializing in engineering, architecture, science, technology education and research, promoting innovation, sustainability, and social responsibility. | Higher Education | 🇪🇸 Barcelona | 5,306 | 1971 |
| 42 | [Universidad de Zaragoza](https://www.tamtam.ai/c/universidad-de-zaragoza) (unizar.es)<br>A prestigious center of technological innovation in the Ebro Valley with strong relationships with Spanish and European universities, tracing its origins back to Ecclesiastical Schools | Education Administration Programs | 🇪🇸 Zaragoza | 5,038 | 1474 |
| 43 | [Universidad Rey Juan Carlos](https://www.tamtam.ai/c/universidad-rey-juan-carlos) (urjc.es)<br>Public university offering diverse degree programs, including English and blended learning, promoting cooperation with institutions for academic excellence. | Higher Education | 🇪🇸 Móstoles | 4,984 | 1996 |
| 44 | [Sener](https://www.tamtam.ai/c/sener) (group.sener)<br>Responds to demanding challenges with innovative, efficient solutions, advancing society across aerospace, defense, energy, mobility, data centers, and digital sectors for 70 years. | Engineering Services | 🇪🇸 Getxo | 4,878 | 1956 |
| 45 | [Management Solutions](https://www.tamtam.ai/c/management-solutions) (managementsolutions.com)<br>Providing consulting services in strategy, organization, risk management, and technology for financial, energy, and telecommunications sectors worldwide. | Business Consulting and Services | 🇪🇸 Madrid | 4,798 | 2002 |
| 46 | [EHU](https://www.tamtam.ai/c/ehu) (ehu.eus)<br>A public research university rooted in Basque society, open to the world, with intellectual leadership and ethical and social commitment | Higher Education | 🇪🇸 Leioa | 4,520 | 1980 |
| 47 | [Universidad de Salamanca](https://www.tamtam.ai/c/universidad-de-salamanca) (usal.es)<br>A prestigious university founded in 1218, offering a wide range of undergraduate, master's, doctoral, and continuing education programs to over 30,000 students | Higher Education | 🇪🇸 Salamanca | 4,385 | 1218 |
| 48 | [Hospital Universitari Vall d'Hebron](https://www.tamtam.ai/c/hospital-universitari-vall-d-hebron) (vallhebron.com)<br>A leading hospital complex in Catalonia with four large centers offering a wide range of medical and surgical specialties | Hospitals and Health Care | 🇪🇸 Barcelona | 4,361 | 1955 |
| 49 | [OHLA Group](https://www.tamtam.ai/c/ohla-group) (ohla-group.com)<br>A global leader in construction, engineering, and development projects, focusing on transport infrastructure, unique buildings, and sustainable progress in various regions worldwide | Construction | 🇪🇸 Madrid | 4,270 | 1911 |
| 50 | [GMV](https://www.tamtam.ai/c/gmv) (gmv.com)<br>A technologically advanced business group offering solutions and services in various sectors including cybersecurity, defense, healthcare, and intelligent transportation systems | IT Services and IT Consulting | 🇪🇸 Tres Cantos | 4,163 | 1984 |
| 51 | [GRI RENEWABLE INDUSTRIES SL](https://www.tamtam.ai/c/gri-renewable-industries-sl) (gri.com.es)<br>Manufactures towers and flanges for the wind energy sector globally, including onshore and offshore towers, wind flanges, and wind castings components. | Semiconductor Manufacturing | 🇪🇸 Madrid | 4,000 | 2008 |
| 52 | [Universidade do Minho](https://www.tamtam.ai/c/universidade-do-minho) (uminho.pt)<br>Higher education institution in Portugal focusing on quality education, cutting-edge research, sustainability, and international recognition in a dynamic environment. | Higher Education | 🇪🇸 Braga | 3,939 | 1973 |
| 53 | [SEM](https://www.tamtam.ai/c/sem-gijon) (semgrupo.es)<br>Specializing in surface treatment, we are pioneers in metal coatings for various sectors including equipment, aerospace, energy generation, and oil & gas industries | Aviation and Aerospace Component Manufacturing | 🇪🇸 Gijón | 3,931 | 1956 |
| 54 | [Universidad de Santiago de Compostela](https://www.tamtam.ai/c/universidad-de-santiago-de-compostela) (usc.gal)<br>Public university in Galicia, Spain, offering diverse academic programs across two campuses with numerous departments and degree options. | Higher Education | 🇪🇸 Santiago de Compostela | 3,872 | 1495 |
| 55 | [HM Hospitales](https://www.tamtam.ai/c/hm-hospitales) (hmhospitales.com)<br>Private healthcare group with 54 centers offering specialized hospitals, clinics, and integrated care focused on quality, innovation, and patient wellbeing. | Wellness and Fitness Services | 🇪🇸 Madrid | 3,803 | 1989 |
| 56 | [Barcelona Children's Hospital Sant Joan de Déu](https://www.tamtam.ai/c/barcelona-children-s-hospital-sant-joan-de-deu) (sjdhospitalbarcelona.org)<br>A teaching hospital specializing in pediatrics, gynecology, and obstetrics in Barcelona, Catalonia Privately owned, affiliated with the Hospitaller Order of St John of God | Hospitals and Health Care | 🇪🇸 Esplugues de Llobregat | 3,728 | 1867 |
| 57 | [Oesia](https://www.tamtam.ai/c/oesia) (grupooesia.com)<br>Oesía is a multinational technology consultancy firm with divisions in ICT and security/defense, specializing in projects for clients worldwide Their innovative solutions and services drive value and growth | IT Services and IT Consulting | 🇪🇸 Rivas | 3,697 | 1976 |
| 58 | [Hospital del Mar](https://www.tamtam.ai/c/hospital-del-mar) (hospitaldelmar.cat)<br>Modern general hospital treating medium and high complexity pathologies, affiliated with a university and emphasizing research, located in a diverse, multicultural area | Hospitals and Health Care | 🇪🇸 Barcelona | 3,654 | 1983 |
| 59 | [University of Navarra](https://www.tamtam.ai/c/university-of-navarra) (unav.edu)<br>Private research university with global campuses, focusing on academic and personal growth, offering diverse programs, and contributing to medical research and cultural enrichment. | Education Administration Programs | 🇪🇸 Pamplona | 3,643 | 1952 |
| 60 | [Applus+ Idiada](https://www.tamtam.ai/c/applus-idiada) (applusidiada.com)<br>Global automotive partner providing design, engineering, testing, homologation, and validation services with advanced facilities and expert professionals worldwide. | Motor Vehicle Manufacturing | 🇪🇸 Santa Oliva | 3,500 | 1971 |
| 61 | [Universidad de Oviedo](https://www.tamtam.ai/c/universidad-de-oviedo) (uniovi.es)<br>Public higher education institution, offers diverse undergraduate and postgraduate programs, including bilingual and Erasmus Mundus degrees, and conducts 80% of regional R&D. | Higher Education | 🇪🇸 Oviedo | 3,498 | 1608 |
| 62 | [Ingeteam](https://www.tamtam.ai/c/ingeteam-zamudio) (ingeteam.com)<br>A global team of over 3,500 experts providing innovative solutions in renewable energy, electric vehicle chargers, green hydrogen production, and water technology | Electrical Equipment Manufacturing | 🇪🇸 Zamudio | 3,443 | 1972 |
| 63 | [ITP Aero](https://www.tamtam.ai/c/itp-aero) (itpaero.com)<br>A leading aircraft engine and component company developing technology for a sustainable aerospace future, with global facilities and commitment to net zero carbon emissions | Aviation and Aerospace Component Manufacturing | 🇪🇸 Zamudio | 3,345 | 1989 |
| 64 | [Universidad de Córdoba](https://www.tamtam.ai/c/universidad-de-cordoba) (uco.es)<br>The University of Cordoba focuses on agricultural, health sciences, humanities, and legal and social sciences education, leading the ceiA3 International Excellence Campus | Higher Education | 🇪🇸 Córdoba | 3,304 | 1972 |
| 65 | [Hospital Universitario La Paz](https://www.tamtam.ai/c/hospital-universitario-la-paz) (comunidad.madrid)<br>A public hospital in Madrid that offers specialized healthcare services to patients from Spain and other countries, with a strong reputation in the healthcare industry | Hospitals and Health Care | 🇪🇸 Madrid | 3,225 | 1964 |
| 66 | [Plexus Tech](https://www.tamtam.ai/c/plexus-tech) (plexus.es)<br>A technology company specializing in various sectors, offering 360º services with a focus on innovation to enhance people's lives | IT Services and IT Consulting | 🇪🇸 Santiago de Compostela | 3,154 | 2000 |
| 67 | [Hospital Gregorio Marañón](https://www.tamtam.ai/c/hospital-gregorio-maranon) (hggm.es)<br>A public hospital in Madrid known for highly trained professionals, teaching and research, technological advancements, and national/international specialty care | Medical Practices | 🇪🇸 Madrid | 3,146 |  |
| 68 | [Fluidra](https://www.tamtam.ai/c/fluidra) (fluidra.com)<br>Global leader in pool and wellness equipment, offering innovative products and services in over 45 countries with a trusted brand portfolio | Manufacturing | 🇪🇸 Sant Cugat del Vallès | 3,137 | 1969 |
| 69 | [Fundación Hospitalarias](https://www.tamtam.ai/c/fundacion-hospitalarias) (fundacionhospitalarias.org)<br>Non-profit institution providing specialized care, assistance, and social reintegration for individuals with mental illness, intellectual disabilities, and other conditions worldwide | Hospitals and Health Care | 🇪🇸 Madrid | 3,112 | 1881 |
| 70 | [Desigual](https://www.tamtam.ai/c/desigual) (desigual.com)<br>A fashion company that creates unique pieces for women, men, kids, and accessories, focusing on self-expression through patchwork, textures, and graphic motifs | Retail Apparel and Fashion | 🇪🇸 Barcelona | 3,072 | 1984 |
| 71 | [Navantia](https://www.tamtam.ai/c/navantia-madrid) (navantia.es)<br>Civil and military shipbuilding, ship repairs, turbine manufacturing, engine production, and weapon systems development with centuries of experience. | Shipbuilding | 🇪🇸 Madrid | 2,977 |  |
| 72 | [Universidad Pontificia Comillas](https://www.tamtam.ai/c/universidad-pontificia-comillas) (comillas.edu)<br>A long-standing university with Jesuit leadership, emphasizing tradition, modern education, and strong connections with business, professional, and social sectors | Higher Education | 🇪🇸 Madrid | 2,920 | 1890 |
| 73 | [Hospital de la Santa Creu i Sant Pau](https://www.tamtam.ai/c/hospital-de-la-santa-creu-i-sant-pau-barcelona) (santpau.cat)<br>A centuries-old highly complex hospital in Spain, primarily serving Barcelona and Catalonia, with a prominent national and international reputation | Hospitals and Health Care | 🇪🇸 Barcelona | 2,826 | 1401 |
| 74 | [Orona Group](https://www.tamtam.ai/c/orona-group) (orona-group.com)<br>Design manufacture install maintain modernize lifts escalators with innovations in traffic management space optimization comfort safety across Europe. | Mechanical Or Industrial Engineering | 🇪🇸 Hernani | 2,818 | 1964 |
| 75 | [Factorial](https://www.tamtam.ai/c/factorial) (factorialhr.com)<br>A leading HR software for SMEs, automating administrative tasks worldwide Offers solutions like time management, talent management, recruitment, and more | Software Development | 🇪🇸 Barcelona | 2,728 | 2016 |
| 76 | [Europastry](https://www.tamtam.ai/c/europastry) (europastry.com)<br>A leading bakery company specializing in frozen doughs for bread, pastries, and snacks, rooted in traditional baking with a strong focus on innovation and sustainability | Food and Beverage Services | 🇪🇸 Barcelona | 2,712 | 1987 |
| 77 | [Exeltis](https://www.tamtam.ai/c/exeltis) (exeltis.com)<br>Innovative global organization in the pharmaceutical sector, committed to improving health through the development and marketing of medicinal products worldwide | Pharmaceutical Manufacturing | 🇪🇸 Madrid | 2,659 | 2003 |
| 78 | [Banco de España](https://www.tamtam.ai/c/banco-de-espana) (bde.es)<br>National central bank and banking supervisor, managing monetary policy, currency issuance, payment systems, and financial system stability in Spain. | Banking | 🇪🇸 Madrid | 2,585 | 1782 |
| 79 | [CIE Automotive](https://www.tamtam.ai/c/cie-automotive) (cieautomotive.com)<br>An industrial group specializing in supplying automotive components and subassemblies on a global scale, offering various technologies to meet customer needs | Motor Vehicle Parts Manufacturing | 🇪🇸 Bilbao | 2,561 | 2002 |
| 80 | [Power Electronics](https://www.tamtam.ai/c/power-electronics) (power-electronics.com)<br>Leading solar inverter manufacturer, energy storage solutions, projects across 36 countries, prevents CO2 emissions, global energy benchmark. | Renewable Energy Semiconductor Manufacturing | 🇪🇸 Llíria | 2,513 | 1987 |
| 81 | [CUPA GROUP](https://www.tamtam.ai/c/cupa-group) (cupagroup.com)<br>Leading multinational in natural slate and stone, developing innovative solutions for energy efficiency and sustainability in construction worldwide. | Wholesale Building Materials | 🇪🇸 Sobradelo de Valdeorras | 2,500 | 1968 |
| 82 | [Laboratorios Normon](https://www.tamtam.ai/c/laboratorios-normon) (normon.com)<br>A Spanish pharmaceutical laboratory with over 85 years of experience specializing in high-quality medicines, offering a wide range of products internationally | Pharmaceutical Manufacturing | 🇪🇸 Tres Cantos | 2,427 | 1937 |
| 83 | [Almirall](https://www.tamtam.ai/c/almirall) (almirall.com)<br>Global biopharmaceutical company focused on medical dermatology, developing innovative solutions for dermatological diseases through R&D, healthcare partnerships, and global presence in 100+ countries | Pharmaceutical Manufacturing | 🇪🇸 Barcelona | 2,401 |  |
| 84 | [Chemo](https://www.tamtam.ai/c/chemo) (chemopharmaceuticals.com)<br>Specializing in pharmaceutical research, development, manufacturing, and sales worldwide, with a focus on innovation and sustainable development to improve health and quality of life | Pharmaceutical Manufacturing | 🇪🇸 Madrid | 2,388 | 1977 |
| 85 | [Clínica Universidad de Navarra](https://www.tamtam.ai/c/clinica-universidad-de-navarra) (cun.es)<br>A highly specialized medical center affiliated with the University of Navarra, known for innovative technology, team-based approach, research, teaching, and personalized patient care | Health and Human Services | 🇪🇸 Pamplona | 2,347 | 1962 |
| 86 | [Horse Technologies](https://www.tamtam.ai/c/horse-technologies) (horse-powertrain.com)<br>Global partner for low-emission powertrain solutions in automotive and industrial sectors, leveraging Renault Group expertise to accelerate decarbonisation with tailored solutions worldwide | Engines and Power Transmission Equipment Manufacturing | 🇪🇸 Alcobendas | 2,327 | 2023 |
| 87 | [ESTEVE](https://www.tamtam.ai/c/esteve) (esteve.com)<br>International pharmaceutical company focused on improving people's lives through innovative solutions and environmentally sustainable practices, with production sites globally | Pharmaceutical Manufacturing | 🇪🇸 Barcelona | 2,305 | 1929 |
| 88 | [Universitat de Girona](https://www.tamtam.ai/c/universitat-de-girona) (udg.edu)<br>A public institution in Catalonia focused on teaching, research, and societal development through knowledge creation and dissemination in various fields | Higher Education | 🇪🇸 Girona | 2,304 | 1991 |
| 89 | [bonÀrea Agrupa](https://www.tamtam.ai/c/bonarea-agrupa) (bonarea-agrupa.com)<br>The company specializes in the agri-food sector, handling all aspects from livestock farming to product distribution, ensuring quality, safety, and efficiency | Food and Beverage Services | 🇪🇸 Guissona | 2,251 |  |
| 90 | [Hospital Universitari de Bellvitge](https://www.tamtam.ai/c/hospital-universitari-de-bellvitge) (bellvitgehospital.cat)<br>Tertiary-care teaching facility with 700 beds, offering high complexity medical care to over 2 million people, ranked among the top hospitals in the state | Hospitals and Health Care | 🇪🇸 L'Hospitalet de Llobregat | 2,231 | 1972 |
| 91 | [ISDIN](https://www.tamtam.ai/c/isdin) (isdin.com)<br>International pharmaceutical company specializing in dermatology solutions, providing treatments, prevention and maintenance for skin conditions worldwide through research and innovation | Pharmaceutical Manufacturing | 🇪🇸 Barcelona | 2,172 | 1975 |
| 92 | [University of Deusto](https://www.tamtam.ai/c/university-of-deusto) (deusto.es)<br>A renowned university offering competency-based education, values-driven teaching, specialized research, and an international perspective for over 125 years | Higher Education | 🇪🇸 Bilbao | 2,169 | 1886 |
| 93 | [Hospital La Fe de Valencia](https://www.tamtam.ai/c/hospital-la-fe-de-valencia) (hospital-lafe.com)<br>A leading public healthcare center in Spain's Valencia region, offering comprehensive medical services, teaching programs, and research facilities with over 7,000 staff members | Wellness and Fitness Services | 🇪🇸 Valencia | 2,157 | 1968 |
| 94 | [UCAM Universidad Católica San Antonio de Murcia](https://www.tamtam.ai/c/ucam-universidad-catolica-san-antonio-de-murcia) (ucam.edu)<br>A private university established in 1996, dedicated to educating students, advancing research, and contributing to society and cultural development | Higher Education | 🇪🇸 Guadalupe | 2,116 | 1996 |
| 95 | [HIPRA](https://www.tamtam.ai/c/hipra) (hipra.com)<br>Biotechnological pharmaceutical company specializing in innovative vaccines and diagnostic services for animal and human health worldwide | Pharmaceutical Manufacturing | 🇪🇸 Amer | 2,113 |  |
| 96 | [Nippon Sanso Europe](https://www.tamtam.ai/c/nippon-sanso-europe) (nippongases.com)<br>A leading European company in industrial and medical gases, offering innovative solutions for various industries, prioritizing safety, quality, and sustainability | Chemical Manufacturing | 🇪🇸 Madrid | 2,106 |  |
| 97 | [Talgo](https://www.tamtam.ai/c/talgo) (talgo.com)<br>Specializing in designing, manufacturing, and servicing trains worldwide, this company is a global leader in high-speed trains with over 70 years of experience | Railroad Equipment Manufacturing | 🇪🇸 Las Rozas de Madrid | 2,077 | 1942 |
| 98 | [Hospital Privado Universitario de Córdoba](https://www.tamtam.ai/c/hospital-privado-universitario-de-cordoba) (hospitalprivado.com.ar)<br>A private university hospital in Córdoba, Argentina, dedicated to providing high-quality medical care, research, and education for over 60 years | Wellness and Fitness Services | 🇪🇸 Córdoba | 2,041 | 1957 |
| 99 | [MAXAM](https://www.tamtam.ai/c/maxam) (maxamcorp.com)<br>Design, development, manufacture of energetic materials including blasting solutions for mining, cartridges for shooting, and defense sector products worldwide. | Chemical Manufacturing | 🇪🇸 | 2,017 | 1872 |
| 100 | [DR. SCHAR ESPAÑA, SLU](https://www.tamtam.ai/c/dr-schar-espana-slu) (drschaer.com)<br>A global company founded in 1922 in the Alps, committed to improving special nutritional needs with products available in over 100 countries | Food and Beverage Manufacturing | 🇪🇸 Burgstall / Postal | 2,012 | 1981 |

## How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 11, 2026.

## More company lists in Spain

- [The largest companies in Spain](https://www.tamtam.ai/l/largest-companies-spain) (10,893)
- [Multinational companies in Spain](https://www.tamtam.ai/l/multinational-companies-spain) (2,706)
- [Retail chains in Spain](https://www.tamtam.ai/l/retail-chains-spain) (1,251)
- [Manufacturers in Spain](https://www.tamtam.ai/l/manufacturers-spain) (1,080)
- [Wellness and Fitness Services companies in Spain](https://www.tamtam.ai/l/wellness-and-fitness-services-companies-spain) (879)
- [Healthcare providers in Spain](https://www.tamtam.ai/l/healthcare-providers-spain) (711)
- [Companies with a mobile app in Spain](https://www.tamtam.ai/l/companies-with-mobile-app-spain) (561)
- [Hotel and hospitality groups in Spain](https://www.tamtam.ai/l/hospitality-groups-spain) (539)
- [Family-owned companies in Spain](https://www.tamtam.ai/l/family-owned-companies-spain) (531)
- [Software Development companies in Spain](https://www.tamtam.ai/l/software-development-companies-spain) (530)
- [Professional services firms in Spain](https://www.tamtam.ai/l/professional-services-firms-spain) (522)
- [Critical infrastructure operators in Spain](https://www.tamtam.ai/l/critical-infrastructure-operators-spain) (517)
- [IT services companies in Spain](https://www.tamtam.ai/l/it-services-companies-spain) (484)
- [Financial services firms in Spain](https://www.tamtam.ai/l/financial-services-firms-spain) (482)
- [Food and Beverage Services companies in Spain](https://www.tamtam.ai/l/food-and-beverage-services-companies-spain) (462)
- [SaaS companies in Spain](https://www.tamtam.ai/l/saas-companies-spain) (445)
- [Retail Apparel and Fashion companies in Spain](https://www.tamtam.ai/l/retail-apparel-and-fashion-companies-spain) (439)
- [IT Services and IT Consulting companies in Spain](https://www.tamtam.ai/l/it-services-and-it-consulting-companies-spain) (437)
- [Hospitality companies in Spain](https://www.tamtam.ai/l/hospitality-companies-spain) (435)
- [Consulting firms in Spain](https://www.tamtam.ai/l/consulting-firms-spain) (420)
- [E-commerce companies in Spain](https://www.tamtam.ai/l/ecommerce-companies-spain) (416)
- [Food and beverage companies in Spain](https://www.tamtam.ai/l/food-and-beverage-companies-spain) (416)
- [Hardware manufacturers in Spain](https://www.tamtam.ai/l/hardware-companies-spain) (415)
- [Transportation, Logistics, Supply Chain and Storage companies in Spain](https://www.tamtam.ai/l/transportation-logistics-supply-chain-and-storage-companies-spain) (397)

## The same list elsewhere in Spain

- [Companies with in-house R&D in Catalonia](https://www.tamtam.ai/l/r-and-d-companies-catalonia) (324)
- [Companies with in-house R&D in Community of Madrid](https://www.tamtam.ai/l/r-and-d-companies-community-of-madrid) (245)
- [Companies with in-house R&D in Valencian Community](https://www.tamtam.ai/l/r-and-d-companies-valencian-community) (102)
- [Companies with in-house R&D in Basque Country](https://www.tamtam.ai/l/r-and-d-companies-basque-country) (99)
- [Companies with in-house R&D in Andalusia](https://www.tamtam.ai/l/r-and-d-companies-andalusia) (89)
- [Companies with in-house R&D in Region of Murcia](https://www.tamtam.ai/l/r-and-d-companies-region-of-murcia) (25)
- [Companies with in-house R&D in Madrid](https://www.tamtam.ai/l/r-and-d-companies-madrid) (158)
- [Companies with in-house R&D in Barcelona](https://www.tamtam.ai/l/r-and-d-companies-barcelona) (122)

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Source: https://www.tamtam.ai/l/r-and-d-companies-spain