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Top 50 research institutes in Ontario

Tamtam tracks 64 research institutes headquartered in Ontario. This list ranks the 50 largest by number of employees on LinkedIn, led by University of Toronto, McMaster University and University of Ottawa. Their median headcount is 1,723. Half of them were founded in 1922 or later. The most common headquarters are Toronto (24), Ottawa (7) and Hamilton (5).

πŸ‡¨πŸ‡¦ Ontario50 companiesUpdated Nov 12, 2026

The largest research institutes in Ontario are predominantly higher education institutions and hospitals. For example, the University of Toronto focuses on research and global education, while McMaster University is known for innovation in education and research. Unity Health Toronto provides primary, community, and specialized care, and The Hospital for Sick Children integrates patient care, research, and education.

These organizations are primarily located in major urban centers. Toronto hosts several of the largest institutions, including York University, which educates students and drives societal change through research, and Toronto Metropolitan University, an urban university focusing on creativity and entrepreneurship. Ottawa also features prominently, with institutions like the University of Ottawa and Carleton University, which combines research and teaching.

#CompanyIndustryHeadquarters EmployeesFounded
1
University of Torontodefygravitycampaign.utoronto.ca

Leading Canadian university focused on research, innovation, and global education to address pressing societal challenges and prepare students for success

Higher Education πŸ‡¨πŸ‡¦ Toronto 28,832 n/a
2
McMaster Universitymcmaster.ca

Leading Canadian university known for innovation in education and research, serving 30,000 students and a global alumni network.

Higher Education πŸ‡¨πŸ‡¦ Hamilton 13,160 1887
3
University of Ottawauottawa.ca

The company is the largest bilingual university in the world, offering education in English and French with a focus on research and global advancements

Higher Education πŸ‡¨πŸ‡¦ Ottawa 12,220 n/a
4
Western Universityuwo.ca

A leading research-intensive university with a global community of students and alumni focused on making change in the world Welcome scholars worldwide

Higher Education πŸ‡¨πŸ‡¦ London 12,137 1878
5
York Universityyorku.ca

Educates students, fosters career advancement, and drives positive societal change through research and community engagement.

Higher Education πŸ‡¨πŸ‡¦ Toronto 11,154 1959
6
Queen's Universityqueensu.ca

A prestigious university known for its research, innovation, and commitment to addressing global challenges through scholarship and international engagement

Higher Education πŸ‡¨πŸ‡¦ Kingston 9,891 1841
7
Unity Health Torontounityhealth.to

A health network in Toronto providing primary, community, specialized, and long-term care services, as well as investing in research and education

Hospitals and Health Care πŸ‡¨πŸ‡¦ Toronto 8,686 2017
8
The Hospital for Sick Childrensickkids.ca

Leading pediatric hospital integrating patient care, research, and education to advance children's health and develop innovative treatments globally.

Hospitals and Health Care πŸ‡¨πŸ‡¦ Toronto 8,636 1875
9
Toronto Metropolitan Universitytorontomu.ca

Innovative urban university in Toronto, focusing on creativity, entrepreneurship, inclusivity, and global community engagement to serve societal needs

Higher Education πŸ‡¨πŸ‡¦ Toronto 8,478 n/a
10
University of Guelphuoguelph.ca

Dedicated to improving quality of life through innovative research and education in essential areas like water, food, health, and environment

Higher Education πŸ‡¨πŸ‡¦ Guelph 7,725 1964
11
London Health Sciences Centre (LHSC)lhsc.on.ca

Acute care teaching hospital offering specialized clinical services, leading in discovery and innovation, providing exceptional patient care and training healthcare professionals

Hospitals and Health Care πŸ‡¨πŸ‡¦ London 7,092 n/a
12
Carleton Universitycarleton.ca

University located near government and high tech companies, combining research and teaching to provide superior education and solve real problems.

Higher Education πŸ‡¨πŸ‡¦ Ottawa 6,886 1942
13
Hamilton Health Scienceshamiltonhealthsciences.ca

Healthcare organization delivering specialized cardiac, stroke, trauma, cancer, palliative, and pediatric care to southwestern Ontario and beyond.

Hospitals and Health Care πŸ‡¨πŸ‡¦ Hamilton 6,690 n/a
14
St. Michael's Hospitalunityhealth.to

A leading hospital providing compassionate care, medical education in 27 disciplines, and research through the Keenan Research Centre for global impact

Hospitals and Health Care πŸ‡¨πŸ‡¦ Toronto 4,868 1892
15
National Research Council Canada / Conseil national de recherches Canadanrc.canada.ca

Largest government research organization supporting innovation, helping SMEs scale, connecting Canadian innovators with advanced R&D capabilities, fostering partnerships.

Research Services πŸ‡¨πŸ‡¦ Ottawa 4,732 1916
16
Natural Resources Canada (NRCan)natural-resources.canada.ca

A department of the Government of Canada focused on advancing sustainable resource management, economic growth, and environmental stewardship through innovative policies and programs

Government Administration πŸ‡¨πŸ‡¦ Ottawa 4,579 n/a
17
CAMHcamh.ca

A leading teaching hospital in Canada focused on transforming lives through clinical care, research, education, and advocacy for mental health and addiction issues

Hospitals and Health Care πŸ‡¨πŸ‡¦ Toronto 4,477 1998
18
Sinai Healthsinaihealth.ca

A leading academic health science centre focused on integrated care, innovative research, and educating future healthcare leaders for comprehensive patient care

Hospitals and Health Care πŸ‡¨πŸ‡¦ Toronto 4,083 n/a
19
Wilfrid Laurier Universitywlu.ca

Canadian university focusing on teaching, research, and student satisfaction with programs in arts, business, science, social work, and education.

Higher Education πŸ‡¨πŸ‡¦ Waterloo 4,060 n/a
20
St. Joseph's Healthcare Hamiltonstjoes.ca

A values-based academic health science centre affiliated with McMaster University and Mohawk College, committed to providing integrated, compassionate care and advancing research and education

Hospitals and Health Care πŸ‡¨πŸ‡¦ Hamilton 2,983 1890
21
CHEOcheo.on.ca

A global leader in pediatric health care and research, providing excellence in complex care, education, and community partnership for children and youth

Hospitals and Health Care πŸ‡¨πŸ‡¦ Ottawa 2,784 1974
22
Niagara Collegeniagaracollege.ca

Leader in applied education and training, established in 1967 in Welland and now expanding across the Niagara region for top student satisfaction

Higher Education πŸ‡¨πŸ‡¦ Welland 2,686 1967
23
Ontario Tech Universityontariotechu.ca

Innovative university focusing on advancing knowledge, integrating social and ethical implications of technology, and collaborating on solutions with partners

Higher Education πŸ‡¨πŸ‡¦ Oshawa 2,479 2003
24
Canadian Nuclear Laboratoriescnl.ca

A leading organization in nuclear science and technology, specializing in research, development, engineering, waste management, and decommissioning services for various applications

Research Services πŸ‡¨πŸ‡¦ Chalk River 2,340 2014
25
University of Toronto Scarboroughutsc.utoronto.ca

Innovative university campus promoting diversity, academic excellence, experiential learning, research partnerships, and world-changing ideas in a vibrant environment

Higher Education πŸ‡¨πŸ‡¦ Toronto 1,723 1964

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26
St. Joseph's Health Care Londonsjhc.london.on.ca

A leading academic health care organization in Canada providing compassionate care, teaching, and research to help people live life fully

Hospitals and Health Care πŸ‡¨πŸ‡¦ London 1,707 1869
27
Baycrestbaycrest.org

Global leader in aging and brain health innovations, offering comprehensive care for aging patients, conducting top research in cognitive neuroscience, and promoting global knowledge exchange

Hospitals and Health Care πŸ‡¨πŸ‡¦ Toronto 1,407 1918
28
OCAD Universityocadu.ca

A leading institution in Canada, specializing in art and design education for aspiring students to excel in their creative pursuits

Higher Education πŸ‡¨πŸ‡¦ Toronto 1,343 1876
29
Princess Margaret Cancer Centreuhnresearch.ca

Leading cancer research center with internationally recognized scientists focusing on various aspects of cancer through cutting-edge research and state-of-the-art tools

Medical Practices πŸ‡¨πŸ‡¦ Toronto 1,211 n/a
30
Holland Bloorview Kids Rehabilitation Hospitalhollandbloorview.ca

Pioneering treatments, technologies, and programs for children with disabilities to fully participate in life through a world-class teaching hospital

Hospitals and Health Care πŸ‡¨πŸ‡¦ Toronto 1,086 n/a
31
Ivey Business School at Western Universityivey.uwo.ca

A business school specializing in leadership development with experiential learning, offering undergraduate, postgraduate, and executive programs affiliated with a university

Higher Education πŸ‡¨πŸ‡¦ London 965 1922
32
Temerty Faculty of Medicine, University of Torontotemertymedicine.utoronto.ca

Leader in medical research and innovation, collaborating with diverse partners to address global health challenges for over a century

Higher Education πŸ‡¨πŸ‡¦ Toronto 913 n/a
33
University of Toronto - Rotman School of Managementrotman.utoronto.ca

A global center for research and teaching excellence in Canada, Rotman School of Management fosters transformative learning and public engagement for creating value in business and society

Higher Education πŸ‡¨πŸ‡¦ Toronto 857 n/a
34
Royal Military College of Canada/Collège militaire royal du Canadarmc-cmr.ca

This bilingual institution provides undergraduate and post-graduate education in both English and French, offering a variety of courses and programs

Defense and Space Manufacturing πŸ‡¨πŸ‡¦ Kingston 770 1874
35
NOSM University | UniversitΓ© EMNOnosm.ca

A medical school focused on training healthcare professionals, leading in community-engaged education and research with a distributed learning approach

Higher Education πŸ‡¨πŸ‡¦ Sudbury 708 2005
36
Ontario Institute for Studies in Education of the University of Torontooise.utoronto.ca

A leading research and graduate institute in education, offering world-class programs for careers in teaching and learning

Higher Education πŸ‡¨πŸ‡¦ Toronto 677 1847
37
Schulich School of Medicine & Dentistryschulich.uwo.ca

The company delivers exceptional education, conducts impactful research, and collaborates with communities to enhance health and well-being for the future

Higher Education πŸ‡¨πŸ‡¦ London 655 1881
38
Royal Ontario Museumrom.on.ca

Showcasing art, culture, and nature from around the world since 1914, with over 13 million objects, including mummies, sculpture, meteorites, and dinosaurs

Museums, Historical Sites, and Zoos πŸ‡¨πŸ‡¦ Toronto 629 1914
39
Vector Institutevectorinstitute.ai

A non-profit organization dedicated to AI research, specializing in machine and deep learning Collaborates with various entities to advance AI adoption and commercialization

Research Services πŸ‡¨πŸ‡¦ Toronto 603 2017
40
Defence Research and Development Canada | Recherche et dΓ©veloppement pour la dΓ©fense Canadadrdc-rddc.gc.ca

Provides department of national defense and armed forces with technological advantages and scientific knowledge through seven research centers to protect interests nationwide.

Defense and Space Manufacturing πŸ‡¨πŸ‡¦ Ottawa 603 n/a
41
DeGroote School of Business - McMaster Universitydegroote.mcmaster.ca

Innovative business school at McMaster University focusing on interdisciplinary thinking and evidence-based management to empower graduates in a fast-paced world

Higher Education πŸ‡¨πŸ‡¦ Hamilton 482 1952
42
Faculty of Engineering - McMaster Universityeng.mcmaster.ca

Inspiring, innovative engineering school fostering collaboration among diverse scholars to solve real-world challenges and create a brighter future

Higher Education πŸ‡¨πŸ‡¦ Hamilton 470 n/a
43
York University - Osgoode Hall Law Schoolosgoode.yorku.ca

A prestigious law school in Toronto offering a range of clinical programs, publications, and the largest law library in the Commonwealth

Higher Education πŸ‡¨πŸ‡¦ Toronto 452 1889
44
Dalla Lana School of Public Health, University of Torontodlsph.utoronto.ca

This company is a prominent organization specializing in public health education, research, and services that have a global and local impact

Higher Education πŸ‡¨πŸ‡¦ Toronto 442 1927
45
ICESices.on.ca

Non-profit organization using population-based health data to produce unbiased knowledge for improving health care policy and decision-making

Research Services πŸ‡¨πŸ‡¦ Toronto 437 1992
46
Ontario Veterinary College, University of Guelphuoguelph.ca

Leader in veterinary education, ranking among the top globally Highly regarded program at University of Guelph for veterinary science

Higher Education πŸ‡¨πŸ‡¦ Guelph 426 1862
47
CHEO Research Institutecheoresearch.ca

The research institute strives to bring life-changing discoveries for children and youth through exceptional talent and technology, promoting trust and equity

Research Services πŸ‡¨πŸ‡¦ Ottawa 417 n/a
48
Lassonde School of Engineering - York Universitylassonde.yorku.ca

The company prepares engineers and scientists to tackle complex global challenges and seize opportunities through a holistic and innovative approach

Higher Education πŸ‡¨πŸ‡¦ Toronto 400 n/a
49
Leslie Dan Faculty of Pharmacy, University of Torontopharmacy.utoronto.ca

A leading Canadian pharmacy school offering cutting-edge educational programs and research focusing on modern drug therapy and healthcare innovation

Hospitals and Health Care πŸ‡¨πŸ‡¦ Toronto 372 1882
50
Canadian Memorial Chiropractic Collegecmcc.ca

A leading chiropractic institution offering rigorous academic and clinical preparation, research opportunities, and advanced technology to enhance patient care and student education

Higher Education πŸ‡¨πŸ‡¦ Toronto 355 1945

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How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 12, 2026.

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