# The 30 largest research institutes in São Paulo

Tamtam tracks 32 research institutes headquartered in São Paulo. This list ranks the 30 largest by number of employees on LinkedIn, led by Einstein Hospital Israelita, USP - Universidade de São Paulo and Sírio-Libanês. Their median headcount is 1,298. Half of them were founded in 1954 or later.

These research institutes in São Paulo are primarily large organizations in higher education and healthcare. They include major universities and hospitals dedicated to both patient care and scientific advancement. Examples are Einstein Hospital Israelita, which offers cutting-edge treatments, and USP - Universidade de São Paulo, recognized globally for its educational and research contributions. Sírio-Libanês is another prominent healthcare institution with a long history of medical services, education, and research.

A clear pattern among these institutions is their focus on public health and education. Many, like Hospital das Clínicas da Faculdade de Medicina da USP and Santa Casa de Misericórdia de São Paulo, are public or philanthropic entities with a long-standing commitment to community service. A significant number were founded in the mid-20th century, indicating a period of growth in structured research and educational initiatives in the region.

🇧🇷 São Paulo · 30 companies · Updated Nov 12, 2026

| # | Company | Industry | Headquarters | Employees | Founded |
|---|---|---|---|---|---|
| 1 | [Einstein Hospital Israelita](https://www.tamtam.ai/c/einstein-hospital-israelita) (einstein.br)<br>A leading healthcare institution offering cutting-edge treatments, compassionate care, social responsibility initiatives, and education and research programs for the community | Hospitals and Health Care | 🇧🇷 São Paulo | 40,979 |  |
| 2 | [USP - Universidade de São Paulo](https://www.tamtam.ai/c/usp-universidade-de-sao-paulo) (www5.usp.br)<br>Educates students, conducts research, and contributes to scientific productivity, recognized by global rankings for faculty, student, and staff dedication. | Higher Education | 🇧🇷 São Paulo | 23,205 | 1934 |
| 3 | [Sírio-Libanês](https://www.tamtam.ai/c/sirio-libanes) (hospitalsiriolibanes.org.br)<br>A renowned healthcare institution with philanthropic roots, offering top-notch medical services, cutting-edge technology, education, research, and social responsibility initiatives for 100 years | Hospitals and Health Care | 🇧🇷 São Paulo | 19,137 | 1921 |
| 4 | [Universidade Estadual Paulista Júlio de Mesquita Filho](https://www.tamtam.ai/c/universidade-estadual-paulista-julio-de-mesquita-filho) (www2.unesp.br)<br>A leading Brazilian university with a multicampus structure offering quality education, research opportunities, and community services to students and society | Higher Education | 🇧🇷 São Paulo | 9,365 | 1976 |
| 5 | [Hospital das Clínicas da Faculdade de Medicina da USP](https://www.tamtam.ai/c/hospital-das-clinicas-da-faculdade-de-medicina-da-usp) (hc.fm.usp.br)<br>A public institution affiliated with a medical school in São Paulo, dedicated to health public healthcare through education, research, assistance, and management | Hospitals and Health Care | 🇧🇷 São Paulo | 8,241 | 1944 |
| 6 | [Santa Casa de Misericórdia de São Paulo](https://www.tamtam.ai/c/santa-casa-de-misericordia-de-sao-paulo) (doar.santacasasp.org.br)<br>A long-standing philanthropic institution providing high-quality healthcare services, medical education, and research with a focus on complex treatments and diagnostic services | Hospitals and Health Care | 🇧🇷 São Paulo | 8,239 | 1560 |
| 7 | [Unifesp - Universidade Federal de São Paulo](https://www.tamtam.ai/c/unifesp-universidade-federal-de-sao-paulo) (portal.unifesp.br)<br>Specialized institution in health sciences, offering training for human resources and conducting scientific research Provides clinical practice and welfare services | Higher Education | 🇧🇷 São Paulo | 7,476 | 1994 |
| 8 | [Universidade Presbiteriana Mackenzie](https://www.tamtam.ai/c/universidade-presbiteriana-mackenzie) (mackenzie.br)<br>Educates individuals for citizenship, fosters personal and societal development through teaching, research, extension, cultural, sports, social, and spiritual activities, grounded in reformed Christian faith. | Higher Education | 🇧🇷 São Paulo | 5,286 | 1870 |
| 9 | [Instituto do Câncer do Estado de São Paulo - ICESP](https://www.tamtam.ai/c/instituto-do-cancer-do-estado-de-sao-paulo-icesp) (icesp.org.br)<br>A leading oncology center in Latin America, focused on providing high-quality care, education, and research in the public health system | Hospitals and Health Care | 🇧🇷 São Paulo | 4,018 | 2008 |
| 10 | [Pontifícia Universidade Católica de São Paulo](https://www.tamtam.ai/c/pontificia-universidade-catolica-de-sao-paulo) (www5.pucsp.br)<br>Established in 1946, this renowned Brazilian university upholds Catholic principles while promoting academic freedom and social responsibility, ranking highly nationwide | Higher Education | 🇧🇷 São Paulo | 3,113 | 1946 |
| 11 | [Fundação Faculdade de Medicina](https://www.tamtam.ai/c/fundacao-faculdade-de-medicina) (ffm.br)<br>A non-profit foundation supporting education, research, and healthcare at the University of São Paulo's Medical School and Hospital | Non-profit Organizations | 🇧🇷 São Paulo | 2,999 | 1986 |
| 12 | [FAPESP](https://www.tamtam.ai/c/fapesp) (fapesp.br)<br>FAPESP is a leading agency funding scientific and technological research in São Paulo, supporting projects, exchanges, and dissemination of knowledge | Research Services | 🇧🇷 São Paulo | 2,334 | 1962 |
| 13 | [Insper Instituto de Ensino e Pesquisa](https://www.tamtam.ai/c/insper-instituto-de-ensino-e-pesquisa) (insper.edu.br)<br>A non-profit institution offering education and research in business, economics, and law, with a modern campus in São Paulo and international partnerships | Higher Education | 🇧🇷 São Paulo | 1,962 | 1987 |
| 14 | [AFIP-Associação Fundo de Incentivo à Pesquisa](https://www.tamtam.ai/c/afip-associacao-fundo-de-incentivo-a-pesquisa) (afip.com.br)<br>A non-profit organization founded in the 1970s to provide financial support for healthcare, research, and community medical services, with a focus on public health | Non-profit Organizations | 🇧🇷 São Paulo | 1,670 | 1976 |
| 15 | [Instituto de Pesquisas Tecnológicas](https://www.tamtam.ai/c/instituto-de-pesquisas-tecnologicas) (ipt.br)<br>A non-profit public research institute in Brazil focused on applied research, technical services, innovation, and professional education to support industry and public policies | Research Services | 🇧🇷 São Paulo | 1,298 | 1899 |
| 16 | [Escola Politécnica da USP](https://www.tamtam.ai/c/escola-politecnica-da-usp) (poli.usp.br)<br>A prestigious engineering school in Latin America offering a wide range of undergraduate, graduate, and specialization courses with excellent teaching and research facilities | Higher Education | 🇧🇷 São Paulo | 1,267 | 1893 |
| 17 | [Faculdade de Ciências Médicas da Santa Casa de São Paulo](https://www.tamtam.ai/c/faculdade-de-ciencias-medicas-da-santa-casa-de-sao-paulo) (favc.fcmsantacasasp.edu.br)<br>The organization established in 1962 promotes medical education, supports scientific research, and addresses medical-social issues by training professionals and producing scientific knowledge | Higher Education | 🇧🇷 São Paulo | 1,063 | 1963 |
| 18 | [IPEN](https://www.tamtam.ai/c/ipen) (ipen.br)<br>An institute specializing in energy and nuclear research, promoting scientific advancements and innovation in the field | Government Administration | 🇧🇷 São Paulo | 987 | 1956 |
| 19 | [Escola Paulista de Medicina - EPM/UNIFESP](https://www.tamtam.ai/c/escola-paulista-de-medicina-epm-unifesp) (unifesp.br)<br>An institution offering a wide range of medical education programs, including Medicine, Nursing, Biomedical Sciences, Audiology, and Ophthalmic Technology Producing competent healthcare professionals | Higher Education | 🇧🇷 São Paulo | 818 | 1933 |
| 20 | [Instituto Dante Pazzanese de Cardiologia - IDPC](https://www.tamtam.ai/c/instituto-dante-pazzanese-de-cardiologia-idpc) (idpc.org.br)<br>Specialized in cardiovascular healthcare services, including outpatient care, emergency treatment, and research in cardiovascular diseases, focusing on prevention, diagnosis, treatment, and education | Public Health | 🇧🇷 São Paulo | 738 |  |
| 21 | [Instituição de Ensino FIPE](https://www.tamtam.ai/c/instituicao-de-ensino-fipe) (fipe.org.br)<br>A non-profit organization established in 1973 supporting the Department of Economics at the University of São Paulo, with a focus on education, projects, and economic indicators | Higher Education | 🇧🇷 São Paulo | 656 | 1973 |
| 22 | [Faculdade de Medicina da Universidade de São Paulo](https://www.tamtam.ai/c/faculdade-de-medicina-da-universidade-de-sao-paulo) (fm.usp.br)<br>The organization focuses on undergraduate and postgraduate education, research, and community service related to medicine, physiotherapy, speech therapy, and occupational therapy | Higher Education | 🇧🇷 São Paulo | 641 | 1912 |
| 23 | [Instituto Adolfo Lutz](https://www.tamtam.ai/c/instituto-adolfo-lutz) (ial.sp.gov.br)<br>The organization is a public health institute that leads surveillance, research, and innovation in biomedical, food, and chemical sciences, aiming to protect and improve public health | Hospitals and Health Care | 🇧🇷 São Paulo | 621 |  |
| 24 | [FGV EAESP](https://www.tamtam.ai/c/fgv-eaesp) (eaesp.fgv.br)<br>A high-level research center and leadership training institution with over a hundred international partners and various double degree agreements | Higher Education | 🇧🇷 São Paulo | 477 | 1954 |
| 25 | [Instituto de Saúde](https://www.tamtam.ai/c/instituto-de-saude) (saude.sp.gov.br)<br>The organization evaluates health policies, conducts scientific research, and promotes technological innovation to improve public health policies and the quality of life | Research Services | 🇧🇷 São Paulo | 467 | 1969 |
| 26 | [IPq - Instituto de Psiquiatria do Hospital das Clínicas da FMUSP](https://www.tamtam.ai/c/ipq-instituto-de-psiquiatria-do-hospital-das-clinicas-da-fmusp) (ipqhc.org.br)<br>A psychiatric institute affiliated with a renowned university hospital in São Paulo, Brazil, specializing in research, education, and patient care | Mental Health Care | 🇧🇷 São Paulo | 392 | 1952 |
| 27 | [Institute of Biomedical Sciences - University of Sao Paulo](https://www.tamtam.ai/c/institute-of-biomedical-sciences-university-of-sao-paulo) (icb.usp.br)<br>This institution specializes in teaching and researching various areas of Health Sciences, such as Immunology, Microbiology, and Physiology, to develop innovative solutions for health | Higher Education | 🇧🇷 São Paulo | 371 | 1969 |
| 28 | [FESPSP - Fundação Escola de Sociologia e Politica de São Paulo](https://www.tamtam.ai/c/fespsp-fundacao-escola-de-sociologia-e-politica-de-sao-paulo) (fespsp.org.br)<br>Specializing in sociology, politics, biblioteconomy, and social sciences education, research, and consulting for public and private sectors in Brazil | Higher Education | 🇧🇷 São Paulo | 339 | 1933 |
| 29 | [Instituto Biológico](https://www.tamtam.ai/c/instituto-biologico) (biologico.sp.gov.br)<br>The Biological Institute develops and shares scientific knowledge in animal and plant health, environmental impact, aiming to improve population's quality of life | Research Services | 🇧🇷 São Paulo | 329 | 1927 |
| 30 | [Universidade de São Paulo (USP)](https://www.tamtam.ai/c/universidade-de-sao-paulo-usp) (www5.usp.br)<br>A prestigious public university in São Paulo, Brazil, offering a wide range of courses in teaching, research, and university extension in all areas of knowledge | Higher Education | 🇧🇷 São Paulo | 307 |  |

## How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 12, 2026.

## More company lists in São Paulo

- [The largest companies in São Paulo](https://www.tamtam.ai/l/largest-companies-sao-paulo) (3,842)
- [Multinational companies in São Paulo](https://www.tamtam.ai/l/multinational-companies-sao-paulo) (472)
- [Financial Services companies in São Paulo](https://www.tamtam.ai/l/financial-services-companies-sao-paulo) (440)
- [Retail chains in São Paulo](https://www.tamtam.ai/l/retail-chains-sao-paulo) (397)
- [Financial services firms in São Paulo](https://www.tamtam.ai/l/financial-services-firms-sao-paulo) (381)
- [Education providers in São Paulo](https://www.tamtam.ai/l/education-companies-sao-paulo) (293)
- [Manufacturers in São Paulo](https://www.tamtam.ai/l/manufacturers-sao-paulo) (279)
- [Companies with a mobile app in São Paulo](https://www.tamtam.ai/l/companies-with-mobile-app-sao-paulo) (277)
- [Critical infrastructure operators in São Paulo](https://www.tamtam.ai/l/critical-infrastructure-operators-sao-paulo) (251)
- [IT Services and IT Consulting companies in São Paulo](https://www.tamtam.ai/l/it-services-and-it-consulting-companies-sao-paulo) (239)
- [E-commerce companies in São Paulo](https://www.tamtam.ai/l/ecommerce-companies-sao-paulo) (218)
- [Retail companies in São Paulo](https://www.tamtam.ai/l/retail-companies-sao-paulo) (212)
- [Professional services firms in São Paulo](https://www.tamtam.ai/l/professional-services-firms-sao-paulo) (200)
- [Healthcare providers in São Paulo](https://www.tamtam.ai/l/healthcare-providers-sao-paulo) (197)
- [Corporate groups and holding companies in São Paulo](https://www.tamtam.ai/l/holding-companies-sao-paulo) (182)
- [Fintech companies in São Paulo](https://www.tamtam.ai/l/fintech-companies-sao-paulo) (171)
- [Companies with in-house R&D in São Paulo](https://www.tamtam.ai/l/r-and-d-companies-sao-paulo) (145)
- [Consulting firms in São Paulo](https://www.tamtam.ai/l/consulting-firms-sao-paulo) (138)
- [IT services companies in São Paulo](https://www.tamtam.ai/l/it-services-companies-sao-paulo) (130)
- [Hospitals and Health Care companies in São Paulo](https://www.tamtam.ai/l/hospitals-and-health-care-companies-sao-paulo) (116)
- [Franchise networks in São Paulo](https://www.tamtam.ai/l/franchise-networks-sao-paulo) (114)
- [Subscription businesses in São Paulo](https://www.tamtam.ai/l/subscription-businesses-sao-paulo) (110)
- [Distributors and wholesalers in São Paulo](https://www.tamtam.ai/l/distributors-and-wholesalers-sao-paulo) (103)
- [Publicly traded companies in São Paulo](https://www.tamtam.ai/l/publicly-traded-companies-sao-paulo) (102)

## The same list elsewhere in Brazil

- [Research institutes in Brazil](https://www.tamtam.ai/l/research-institutes-brazil) (278)
- [Research institutes in São Paulo State](https://www.tamtam.ai/l/research-institutes-sao-paulo-state) (62)
- [Research institutes in Rio de Janeiro State](https://www.tamtam.ai/l/research-institutes-rio-de-janeiro-state) (33)
- [Research institutes in Minas Gerais](https://www.tamtam.ai/l/research-institutes-minas-gerais) (31)
- [Research institutes in Rio de Janeiro](https://www.tamtam.ai/l/research-institutes-rio-de-janeiro) (28)

## The same list elsewhere

- [Research institutes in the world](https://www.tamtam.ai/l/research-institutes-in-the-world) (5,686)
- [Research institutes in Latin America](https://www.tamtam.ai/l/research-institutes-in-latin-america) (512)

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Source: https://www.tamtam.ai/l/research-institutes-sao-paulo