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Top 32 AI-native companies in Grand Est

Tamtam tracks 32 AI-native companies headquartered in Grand Est. This list ranks all of them by number of employees on LinkedIn, led by AZmed, Purecontrol and muchbetter.ai. Their median headcount is 16. Half of them were founded in 2019 or later. The most common headquarters are Metz (5), Strasbourg (4) and Schiltigheim (3).

🇫🇷 Grand Est32 companiesUpdated Oct 24, 2026
#CompanyIndustryHeadquarters EmployeesFounded
1
AZmedazmed.co

Develops AI solutions for medical imaging, including X-ray and CT scans, to support diagnostic confidence, improve workflow efficiency, and enhance operational performance.

Medical Equipment Manufacturing 🇫🇷 Paris 105 2018
2
Purecontrolpurecontrol.com

Purecontrol utilizes AI for predictive and real-time control of industrial equipment in the water sector, optimizing efficiency and reducing energy costs

Engineering Services 🇫🇷 Rennes 55 2017
3
muchbetter.aimuchbetter.ai

Develops realistic industry scenarios and virtual clients to help sales and customer support representatives master best practices autonomously through immersive rapid training.

Technology, Information and Internet 🇫🇷 Paris 40 2023
4
Visible Patient Labvisiblepatient.com

Specializes in synthetic medical data, generating large-scale, ultra-realistic 3D medical image datasets using patented AI for AI development, validation, and deployment.

Medical Equipment Manufacturing 🇫🇷 Strasbourg 33 2025
5
OPTACAREoptacare.fr

Development of planning, forecasting, and decision-support solutions tailored to healthcare organizations, improving efficiency, responsiveness, and quality of care.

Software Development 🇫🇷 Rosières-près-Troyes 31 2013
6
APREX solutionsaprex-solutions.com

Transforming video into data for industrial control, scientific experiments, and research, with expertise in vision systems developed for thermonuclear fusion

Software Development 🇫🇷 Nancy 27 2017
7
i-Virtuali-virtual.ai

Development of AI-driven technology for contactless vital sign measurement, enabling integration via API across multiple industries for health data accessibility.

Software Development 🇫🇷 Metz 22 2014
8
Pixacarepixacare.com

A medical imaging app developed by a plastic surgeon and entrepreneurs, featuring AI technology for chronic wound analysis, CE marking, and hospital implementation

Software Development 🇫🇷 Strasbourg 21 2019
9
Vivokavivoka.com

A software company creating Voice Development Kit for simplified development of offline voice AI technologies across various industries

Embedded Software Products 🇫🇷 Metz 20 2015
10
OuiLinkouilink.fr

Software publisher for professionals in the restaurant industry

IT System Custom Software Development 🇫🇷 Saint-Martin-d'Hères 20 2016
11
BrightHeartbrightheart.fr

Ensuring every fetal ultrasound screening exam achieves peak accuracy for mothers and babies, prioritizing top-tier care quality.

Medical Equipment Manufacturing 🇫🇷 Paris 20 2020
12
Amaya Agamaya.ag

An innovative agritech startup using AI to transform agriculture, providing advanced technological solutions to optimize farms, increase productivity, and reduce environmental impact

Technology, Information and Internet 🇫🇷 Reims 20 2022
13
Submagicsubmagic.co

Simplifies video editing for creators and teams, enabling quick creation of short-form content with AI-powered captions, B-rolls, and visual effects.

Software Development 🇫🇷 Paris 20 2023
14
Reecallreecall-platform.com

AI-powered tools automate incoming request management, enabling 24/7 customer support, increasing team productivity, and focusing on customer advisement for immediate success

Software Development 🇫🇷 Paris 18 2019
15
All in Boxapp.allinbox.fr

Data collection, client communication, and customer base development platform with unlimited capabilities Short and effective actions to connect with new clients daily Contact alex@allinboxfr

Desktop Computing Software Products 🇫🇷 Metz 18 2018
16
Sales Closersalescloser.fr

Revolutionize your business by delegating prospecting and contract closing, increasing revenue by up to x2 in 3-6 months while saving time for core activities

Business Consulting and Services 🇫🇷 Guebwiller 16 2012
17
Two-itwo-i.com

A VCA platform utilizing computer vision, data science, and deep learning for instant alerts, video analysis, search, and interactive data visualization

Software Development 🇫🇷 Metz 15 2017
18
coblthinkeo.io

Multi-agent AI platform transforming deal specifics into sales proposals, ready for immediate sending. Streamlines sales operations.

Software Development 🇫🇷 Paris 14 2025
19
IAC.ai : the Intelligent Automation Companyiac.ai

Providing AI and automation services including RPA, chatbots, workflow automation, and augmented workforce to deliver measurable business outcomes.

IT Services and IT Consulting 🇫🇷 Paris 14 2021
20
TenderFactstenderfacts.ai

Innovative tender response platform offering quick, clever, and confident answers Join now for a 30-day free trial

Software Development 🇫🇷 Paris 10 2023
21
LLAAMAllaama.com

European startup specializing in Cloud-Native AI and Data Science, focusing on transparent, traceable, replicable, and reproducible AI workflows with expertise in AI and cloud technologies

Software Development 🇫🇷 Rixheim 10 2019
22
imki | data expert for Gen AIimki.com

A leading provider of augmented creative AI services for the Luxury and Fashion industry offering bespoke solutions that enhance brand creativity responsibly

Software Development 🇫🇷 Schiltigheim 10 2020
23
Healthcare Artificial Intelligencelinkedin.com

A SaaS e-Health solution for sharing and collaborating between patients and care teams, using AI technology to manage medical documents

Technology, Information and Internet 🇫🇷 Paris 9 2024
24
Opscidiaopscidia.com

Utilizing Open Science principles, AI, and NLP to enhance research dissemination and encourage societal impact through research results reuse

Software Development 🇫🇷 Saint-Ouen 9 n/a
25
Jumbo Manajumbomana.com

Development of generative behavioral AI creating human-like virtual avatars for authentic, immersive, and natural user interactions.

Software Development 🇫🇷 Schiltigheim 9 2022
26
SYNAPSIAsynapsia.fr

Specializing in intelligent automation and web/mobile solutions to enhance business performance through digital transformation, offering strategy consulting, process automation, project support, and development services

Technology, Information and Internet 🇫🇷 Yutz 7 n/a
27
Cephalgocephalgo.com

Pioneer in voice analysis for clinical assessment, providing objective, remote measurement of symptoms through speech as a biomarker for digital health and research.

Software Development 🇫🇷 Strasbourg 6 2021
28
Predimed technologypredimed-technology.fr

Predimed technology offers innovative AI-based telemedicine solutions for chronic disease monitoring to improve patient quality of life and prevent hospitalizations

Wellness and Fitness Services 🇫🇷 Schiltigheim 5 n/a
29
MarketMixermarketmixer.net

This company provides AI-powered solutions in pricing automation, BI analytics, and product databases for e-commerce, offering competitive pricing, product data normalization, and drop-shipping support

IT Services and IT Consulting 🇫🇷 Strasbourg 4 2007
30
Odimma Therapeuticsodimma-therapeutics.com

French biotech company focused on personalized cancer immunotherapy, leveraging neoantigens to improve efficacy of current therapies for hard-to-treat cancers Entering clinic soon

Pharmaceutical Manufacturing 🇫🇷 Illkirch-Graffenstaden 4 2017
31
Wiseonewiseone.io

This company has created an AI-powered browser extension designed to improve users' online reading experience by enhancing the content they view

Software Development 🇫🇷 Metz 3 2021
32
Médéeauditez.io

Develops AI solutions for semantic extraction of medical data and offers a tech studio to health startups, guiding innovation from ideation to deployment.

Public Health 🇫🇷 Rosières-près-Troyes 1 2024

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How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Oct 24, 2026.

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