The companies in this list from the Rhône department are primarily young to mid-sized firms focused on artificial intelligence. Many specialize in software development and biotech, applying AI to various sectors. Ziwig Biotech uses AI for non-invasive medical tests, while Nova In Silico offers a clinical trials simulation platform. BeeBryte applies AI to optimize energy consumption in commercial buildings, and LAINX specializes in digital document management solutions.
A clear pattern among these companies is their strong concentration in Lyon, with the majority of headquarters located there. Several firms, including Kurage, Diagnoly, and The QA Company, were founded around 2019-2020, suggesting a common founding era for many of these AI-native businesses.
| # | Company | Employees | |||
|---|---|---|---|---|---|
| 1 |
Ziwig Biotechziwig.com
Pioneering salivary RNA analysis and AI application in biomolecular biology to develop non-invasive tests and biomarkers for chronic diseases, especially women's health. |
92 | |||
| 2 |
Nova In Siliconovainsilico.ai
Provides a clinical trials simulation platform to biotech, pharma, and research centers to optimize drug development and predict trial outcomes. |
61 | |||
| 3 |
BeeBryte - New Ways for Energy Efficiencybeebryte.com
Providing innovative O&M services for HVAC-R systems in commercial buildings, using AI to optimize energy consumption, increase efficiency, and reduce carbon footprint |
57 | |||
| 4 | 53 | ||||
| 5 | 42 | ||||
| 6 |
Antidotfluidtopics.com
A software vendor leveraging advanced research in semantic search to develop a Content Delivery Platform that transforms technical documentation into personalized knowledge hubs |
40 | |||
| 7 |
stanestane-groupe.fr
Expert CRO facilitating clinical research in community medicine through a national professional network, health data warehouse, and platform for real-world health innovation. |
37 | |||
| 8 |
RocketFinrocketfin.ai
Revolutionizes credit risk assessment for agile businesses, combining financial, behavioral, and contextual data for fast, reliable, and customized decisions. |
34 | |||
| 9 |
ProovStationproovstation.com
Automated vehicle inspection, using computer vision to scan vehicles, detect damages, estimate repair costs, and provide SaaS solutions for automotive businesses. |
34 | |||
| 10 | 30 | ||||
| 11 |
Diagnolydiagnoly.com
This company applies computational physics and deep learning to obstetric ultrasound, improving fetal diagnostics, detecting pathologies, and simplifying decision-making for clinicians |
29 | |||
| 12 |
The QA Companyqanswer.ai
Leading AI startup offering enterprise solutions for information access through AI chatbot creation with QAnswer platform Solutions span industries like HR, legal, training, customer support |
27 | |||
| 13 | 26 | ||||
| 14 |
HawkCellhawkcell.com
Revolutionizing healthcare with patented animal MRI solutions for veterinary clinics and research labs, aiming to expand globally in the industry |
25 | |||
| 15 | 24 | ||||
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| 16 |
ReportLinkerreportlinker.com
This company provides AI-powered market intelligence to help businesses predict trends, understand competitive landscapes, and uncover insights for informed decision-making |
23 | |||
| 17 | 22 | ||||
| 18 | 19 | ||||
| 19 | 15 | ||||
| 20 |
Data New Roaddata-newroad.com
Utilizing AI, we support road operators in managing safety, congestion, and pollution by accelerating decision-making in a complex environment |
12 | |||
| 21 |
Inokufuinokufu.com
Edtech company providing software and data for training organizations, offering personalized learning through a search engine with 45 million resources |
12 | |||
| 22 |
PREVIA MEDICALprevia-medical.com
Artificial intelligence forecasts pathologies. Integrates with EHR systems, analyzes patient data, identifies complication risks, and alerts medical staff to enable early treatment. |
11 | |||
| 23 |
Meddenovo Drug Designmeddenovo.com
A company specializing in AI technology and molecular modeling for drug development, offering unique solutions for drug candidate optimization and custom computational services |
10 | |||
| 24 |
Miurosmiuros.com
Miuros provides AI-powered customer service performance platform to help companies streamline operations, analyze data, and enhance customer and agent experience |
9 | |||
| 25 | 6 | ||||
| 26 |
Vivienne Investissementvivienne-investissement.com
Innovative asset-management company utilizing Artificial Intelligence for active management, focusing on rigorous risk management and performance in the long term |
6 | |||
| 27 |
sweeeft.aisweeeft.ai
Boost HR operations with AI, automate hiring, assessing, and training processes AI-powered platform for corporations, agencies, and institutions to build high-performance teams |
6 | |||
| 28 |
CARDIAGScardiags.com
A startup that creates AI-based medical devices connected to cardiology, improving healthcare in the field of heart health |
4 | |||
| 29 |
Abbel
Provides an AI-powered platform for marketing consultants, agencies, and SMEs to centralize, automate, and optimize marketing functions like analysis, targeting, and reporting. |
2 | |||
| 30 |
Algorithmaalgorithma-fr.webflow.io
Incorporating AI, blockchain, and ergonomics to transform competitive intelligence, driving innovation in the sector |
1 | |||
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How this list is built
Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 12, 2026.
More company lists in the Rhône department
- The largest companies in the Rhône department 4,813
- Multinational companies in the Rhône department 577
- Companies with in-house R&D in the Rhône department 509
- Professional services firms in the Rhône department 400
- Manufacturers in the Rhône department 322
- Retail chains in the Rhône department 302
- IT services companies in the Rhône department 286
- SaaS companies in the Rhône department 284
- Software Development companies in the Rhône department 264
- IT Services and IT Consulting companies in the Rhône department 253
- Hardware manufacturers in the Rhône department 243
- Consulting firms in the Rhône department 242
- Business Consulting and Services companies in the Rhône department 219
- Distributors and wholesalers in the Rhône department 185
- Higher Education companies in the Rhône department 155
- Education providers in the Rhône department 154
- Law Practice companies in the Rhône department 152
- Real Estate companies in the Rhône department 151
- Family-owned companies in the Rhône department 149
- Subscription businesses in the Rhône department 149
- Construction companies in the Rhône department 140
- Pharmaceutical companies in the Rhône department 134
- Financial services firms in the Rhône department 132
- Advertising Services companies in the Rhône department 126
The same list elsewhere in France
- AI-native companies in Île-de-France 684
- AI-native companies in Auvergne-Rhône-Alpes 63
- AI-native companies in the Hauts-de-Seine department 47
- AI-native companies in Grand Est 45
- AI-native companies in Occitanie 44
- AI-native companies in Nouvelle-Aquitaine 30
- AI-native companies in Provence-Alpes-Côte d'Azur 28
- AI-native companies in Brittany 25
- AI-native companies in the Haute-Garonne department 25
- AI-native companies in Paris 619
- AI-native companies in Lyon 26