These Rhône-based companies with in-house R&D are primarily large organizations, including public institutions and established manufacturers. Notable examples include bioMérieux, a global provider of in vitro diagnostic solutions, Groupe SEB, a leader in small domestic equipment, and Hospices Civils de Lyon, a major public university hospital. Other significant players are Cegid, a European leader in cloud management solutions, and Gerflor, which produces and distributes flooring and wallcoverings.
The data reveals a concentration of headquarters in Lyon, with several large public universities like Université Lumière Lyon 2 and Université Jean Moulin (Lyon III) contributing to the R&D landscape. The companies represent a mix of sectors, from biotechnology and manufacturing to healthcare, software development, and higher education, indicating a diverse R&D environment within the department.
| # | Company | Employees | |||
|---|---|---|---|---|---|
| 1 |
bioMérieuxbiomerieux.com
A leading provider of in vitro diagnostic solutions worldwide, focusing on improving patient health and ensuring consumer safety through disease detection and contamination analysis |
13,106 | |||
| 2 |
Groupe SEBgroupeseb.com
Leading company small domestic equipment and professional coffee machines, offering innovative products improving daily lives consumers globally, operating nearly 150 countries. |
9,900 | |||
| 3 |
Hospices Civils de Lyon - HCLchu-lyon.fr
Public university hospital provides care, education, research, medical innovation, prevention, and health education with over 22,000 professionals across 14 facilities. |
8,220 | |||
| 4 | 4,896 | ||||
| 5 |
Université Lumière Lyon 2univ-lyon2.fr
Large French public university offering diverse programs from bachelor to doctorate, focusing on research, international partnerships, and societal engagement. |
3,390 | |||
| 6 |
Université Jean Moulin (Lyon III)univ-lyon3.fr
Public university offering multidisciplinary higher education and research in law, management, humanities, and social sciences with strong societal engagement. |
2,461 | |||
| 7 | 2,160 | ||||
| 8 |
emlyon business schoolem-lyon.com
World-renowned business school offering higher education and continued education programs with a focus on skill hybridization, social responsibility, and impactful alumni worldwide |
2,101 | |||
| 9 |
Gerflorgerflor.com
Production and distribution of design-driven, innovative, environmentally-friendly flooring, wallcovering, and finishes across international healthcare, housing, education, sport, transport, retail, and industrial markets. |
2,037 | |||
| 10 |
Sicame Groupsicame-group.com
World leader in production, sales of accessories and services for electrical energy transmission and distribution, safety equipment, and industrial applications. |
1,999 | |||
| 11 |
Reelreelinternational.com
Designs, produces, and maintains complex lifting and handling systems and solutions for highly technical installations in diverse markets like aerospace, nuclear, and energy. |
1,882 | |||
| 12 |
CTCctcgroupe.com
CTC offers cross-disciplinary solutions for the leather, footwear, and textile industries, focusing on ethical practices, cost savings, waste reduction, and performance improvement worldwide |
1,622 | |||
| 13 |
NEMERAnemera.net
Designs, develops, and manufactures drug delivery devices for ophthalmic, nasal, inhalation, dermal, and parenteral routes, prioritizing patient needs and treatment efficacy. |
1,616 | |||
| 14 |
Centre Léon Bérardcentreleonberard.fr
Specialized cancer hospital and research center providing personalized treatment, innovative therapies, and compassionate care to support patients throughout their illness. |
1,418 | |||
| 15 |
SEQENSseqens.com
Worldwide leader pharmaceutical solutions, specialty ingredients. Operates manufacturing sites, R&D centers. Offers broad portfolio active ingredients, intermediates, specialty ingredients. |
1,285 | |||
Want more companies than this list?This page shows the largest ones only. Connect to Tamtam to see every company that matches, filter by size, industry or growth, and reach their decision-makers. | |||||
| 16 |
CNR (Compagnie Nationale du Rhône)tm.fr
French leading producer of 100% renewable electricity, managing the Rhône river for hydroelectricity, navigation, irrigation, and agricultural use, supporting local development and innovation |
1,256 | |||
| 17 |
Le Vinatier - Psychiatrie Universitaire Lyon Métropolech-le-vinatier.fr
Specialized psychiatric hospital providing comprehensive mental health care, treatment, and support services for individuals with mental disorders. |
1,246 | |||
| 18 |
JTEKT European Operationsjtekt.eu
Designs and manufactures automotive components, bearings for various industries, and a range of machine tools for manufacturing jobs. |
1,006 | |||
| 19 |
Clayens NPclayens.com
Transforms high-performance polymers, composites, and precision metal parts, offering tailored solutions from project to production across diverse industrial sectors. |
978 | |||
| 20 |
Aldes Groupealdesgroup.com
Designs, manufactures, and sells integrated solutions for air quality and thermal comfort in residential and commercial buildings, including ventilation, heating, and cooling. |
914 | |||
| 21 | 844 | ||||
| 22 | 835 | ||||
| 23 |
Eurofins Biomniseurofins-biomnis.com
A European leader in specialized medical pathology, providing over 2,500 tests including specialized, authorized analyses with a focus on innovation and international development |
803 | |||
| 24 |
Agicapagicap.com
Elevating cash flow management strategies for businesses to optimize financial operations and achieve greater success |
685 | |||
| 25 |
KEM ONEkemone.com
Industrial chemical company specializing in PVC production with activities from salt extraction to manufacturing, focusing on export markets and promoting diversity and career growth |
667 | |||
| 26 |
Laboratoire Aguettantaguettant-corporate.com
Develops, produces, distributes innovative injectable pharmaceutical specialties for healthcare professionals and patients. European actor in hospital-initiated injectable drugs. |
611 | |||
| 27 |
Gravotechgravotech.com
Design and manufacture of engraving, marking, and cutting equipment with software and consumables for personalization and industrial applications. |
604 | |||
| 28 |
Babolatbabolat.com
Family-owned company, racquet sports equipment supplier, expertise in strings, serving tennis, padel, badminton players worldwide since 1875. |
589 | |||
| 29 | 557 | ||||
| 30 |
Symbiosymbio.one
Designing and mass-producing high-performance StackPack hydrogen-electric fuel cell systems for mobility and stationary applications through specialized Gigafactory facilities in Europe and North America. |
539 | |||
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Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 11, 2026.
More company lists in the Rhône department
- The largest companies in the Rhône department 4,813
- Multinational companies in the Rhône department 577
- Professional services firms in the Rhône department 400
- Manufacturers in the Rhône department 322
- Retail chains in the Rhône department 302
- IT services companies in the Rhône department 286
- SaaS companies in the Rhône department 284
- Software Development companies in the Rhône department 264
- IT Services and IT Consulting companies in the Rhône department 253
- Hardware manufacturers in the Rhône department 243
- Consulting firms in the Rhône department 242
- Business Consulting and Services companies in the Rhône department 219
- Distributors and wholesalers in the Rhône department 185
- Higher Education companies in the Rhône department 155
- Education providers in the Rhône department 154
- Law Practice companies in the Rhône department 152
- Real Estate companies in the Rhône department 151
- Family-owned companies in the Rhône department 149
- Subscription businesses in the Rhône department 149
- Construction companies in the Rhône department 140
- Pharmaceutical companies in the Rhône department 134
- Financial services firms in the Rhône department 132
- Advertising Services companies in the Rhône department 126
- Events Services companies in the Rhône department 126
The same list elsewhere in France
- Companies with in-house R&D in France 8,750
- Companies with in-house R&D in Île-de-France 2,695
- Companies with in-house R&D in Auvergne-Rhône-Alpes 1,460
- Companies with in-house R&D in Occitanie 680
- Companies with in-house R&D in Grand Est 640
- Companies with in-house R&D in Provence-Alpes-Côte d'Azur 613
- Companies with in-house R&D in Nouvelle-Aquitaine 566
- Companies with in-house R&D in the Hauts-de-Seine department 510
- Companies with in-house R&D in Pays de la Loire 480
- Companies with in-house R&D in Hauts-de-France 410
- Companies with in-house R&D in Brittany 366
- Companies with in-house R&D in the Haute-Garonne department 323
- Companies with in-house R&D in the Bouches-du-Rhône department 321
- Companies with in-house R&D in the Isère department 304
- Companies with in-house R&D in Bourgogne-Franche-Comté 261
- Companies with in-house R&D in the Nord department 237
- Companies with in-house R&D in Normandy 227
- Companies with in-house R&D in the Gironde department 225
- Companies with in-house R&D in the Loire-Atlantique department 207
- Companies with in-house R&D in the Essonne department 198
- Companies with in-house R&D in Centre-Val de Loire 195
- Companies with in-house R&D in Paris 1,249
- Companies with in-house R&D in Lyon 192
- Companies with in-house R&D in Toulouse 172