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Companies with in-house R&D headquartered in the Rhône department

Tamtam tracks 509 companies with in-house R&D headquartered in the Rhône department. This list ranks the 30 largest by number of employees on LinkedIn, led by bioMérieux, Groupe SEB and Hospices Civils de Lyon - HCL. Their median headcount is 1,285. Half of them were founded in 1955 or later. The most common headquarters are Lyon (17) and Écully (2).

🇫🇷 Rhône30 companiesUpdated Nov 11, 2026

These Rhône-based companies with in-house R&D are primarily large organizations, including public institutions and established manufacturers. Notable examples include bioMérieux, a global provider of in vitro diagnostic solutions, Groupe SEB, a leader in small domestic equipment, and Hospices Civils de Lyon, a major public university hospital. Other significant players are Cegid, a European leader in cloud management solutions, and Gerflor, which produces and distributes flooring and wallcoverings.

The data reveals a concentration of headquarters in Lyon, with several large public universities like Université Lumière Lyon 2 and Université Jean Moulin (Lyon III) contributing to the R&D landscape. The companies represent a mix of sectors, from biotechnology and manufacturing to healthcare, software development, and higher education, indicating a diverse R&D environment within the department.

#CompanyIndustryHeadquarters EmployeesFounded
1
bioMérieuxbiomerieux.com

A leading provider of in vitro diagnostic solutions worldwide, focusing on improving patient health and ensuring consumer safety through disease detection and contamination analysis

Biotechnology Research 🇫🇷 Marcy-l'Étoile 13,106 1963
2
Groupe SEBgroupeseb.com

Leading company small domestic equipment and professional coffee machines, offering innovative products improving daily lives consumers globally, operating nearly 150 countries.

Manufacturing 🇫🇷 Écully 9,900 1857
3
Hospices Civils de Lyon - HCLchu-lyon.fr

Public university hospital provides care, education, research, medical innovation, prevention, and health education with over 22,000 professionals across 14 facilities.

Hospitals and Health Care 🇫🇷 Lyon 8,220 1796
4
Cegidcegid.com

European leader cloud management solutions finance, HR, accounting, retail, and entrepreneurs. Offers tailored solutions for digital business transformation worldwide.

Software Development 🇫🇷 Lyon 4,896 n/a
5
Université Lumière Lyon 2univ-lyon2.fr

Large French public university offering diverse programs from bachelor to doctorate, focusing on research, international partnerships, and societal engagement.

Higher Education 🇫🇷 Lyon 3,390 1973
6
Université Jean Moulin (Lyon III)univ-lyon3.fr

Public university offering multidisciplinary higher education and research in law, management, humanities, and social sciences with strong societal engagement.

Higher Education 🇫🇷 Lyon 2,461 1973
7
Ceremacerema.fr

Public referent for territory development, assisting government, communities, and businesses in adapting areas to climate change across six activity domains.

Government Administration 🇫🇷 Lyon 2,160 2014
8
emlyon business schoolem-lyon.com

World-renowned business school offering higher education and continued education programs with a focus on skill hybridization, social responsibility, and impactful alumni worldwide

Education Administration Programs 🇫🇷 Lyon 2,101 n/a
9
Gerflorgerflor.com

Production and distribution of design-driven, innovative, environmentally-friendly flooring, wallcovering, and finishes across international healthcare, housing, education, sport, transport, retail, and industrial markets.

Wholesale Building Materials 🇫🇷 Lyon 2,037 1937
10
Sicame Groupsicame-group.com

World leader in production, sales of accessories and services for electrical energy transmission and distribution, safety equipment, and industrial applications.

Manufacturing 🇫🇷 Lyon 1,999 1955
11
Reelreelinternational.com

Designs, produces, and maintains complex lifting and handling systems and solutions for highly technical installations in diverse markets like aerospace, nuclear, and energy.

Industrial Machinery Manufacturing 🇫🇷 Saint-Cyr-au-Mont-d'Or 1,882 1946
12
CTCctcgroupe.com

CTC offers cross-disciplinary solutions for the leather, footwear, and textile industries, focusing on ethical practices, cost savings, waste reduction, and performance improvement worldwide

International Trade and Development 🇫🇷 Lyon 1,622 1899
13
NEMERAnemera.net

Designs, develops, and manufactures drug delivery devices for ophthalmic, nasal, inhalation, dermal, and parenteral routes, prioritizing patient needs and treatment efficacy.

Medical Equipment Manufacturing 🇫🇷 Lyon 1,616 2015
14
Centre Léon Bérardcentreleonberard.fr

Specialized cancer hospital and research center providing personalized treatment, innovative therapies, and compassionate care to support patients throughout their illness.

Hospitals and Health Care 🇫🇷 Lyon 1,418 1923
15
SEQENSseqens.com

Worldwide leader pharmaceutical solutions, specialty ingredients. Operates manufacturing sites, R&D centers. Offers broad portfolio active ingredients, intermediates, specialty ingredients.

Pharmaceutical Manufacturing 🇫🇷 Écully 1,285 2003

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16
CNR (Compagnie Nationale du Rhône)tm.fr

French leading producer of 100% renewable electricity, managing the Rhône river for hydroelectricity, navigation, irrigation, and agricultural use, supporting local development and innovation

Electric Power Generation 🇫🇷 Lyon 1,256 1934
17
Le Vinatier - Psychiatrie Universitaire Lyon Métropolech-le-vinatier.fr

Specialized psychiatric hospital providing comprehensive mental health care, treatment, and support services for individuals with mental disorders.

Hospitals and Health Care 🇫🇷 Bron 1,246 1876
18
JTEKT European Operationsjtekt.eu

Designs and manufactures automotive components, bearings for various industries, and a range of machine tools for manufacturing jobs.

Manufacturing 🇫🇷 Irigny 1,006 2006
19
Clayens NPclayens.com

Transforms high-performance polymers, composites, and precision metal parts, offering tailored solutions from project to production across diverse industrial sectors.

Manufacturing 🇫🇷 Genas 978 1931
20
Aldes Groupealdesgroup.com

Designs, manufactures, and sells integrated solutions for air quality and thermal comfort in residential and commercial buildings, including ventilation, heating, and cooling.

Industrial Machinery Manufacturing 🇫🇷 Vénissieux 914 1925
21
Eskeresker.com

Provides AI automation suite for CFOs to optimize working capital and cashflow, enhancing strategic decision-making and relationships with customers, suppliers, employees.

Software Development 🇫🇷 Villeurbanne 844 1985
22
Coexyacoexya.eu

Offers IT services, specializing in data valuation across customer experience, content, health, legal, location intelligence, and smart data for clients.

IT Services and IT Consulting 🇫🇷 Saint-Didier-au-Mont-d'Or 835 n/a
23
Eurofins Biomniseurofins-biomnis.com

A European leader in specialized medical pathology, providing over 2,500 tests including specialized, authorized analyses with a focus on innovation and international development

Medical and Diagnostic Laboratories 🇫🇷 Lyon 803 1897
24
Agicapagicap.com

Elevating cash flow management strategies for businesses to optimize financial operations and achieve greater success

Software Development 🇫🇷 Lyon 685 2016
25
KEM ONEkemone.com

Industrial chemical company specializing in PVC production with activities from salt extraction to manufacturing, focusing on export markets and promoting diversity and career growth

Chemical Manufacturing 🇫🇷 Lyon 667 2012
26
Laboratoire Aguettantaguettant-corporate.com

Develops, produces, distributes innovative injectable pharmaceutical specialties for healthcare professionals and patients. European actor in hospital-initiated injectable drugs.

Pharmaceutical Manufacturing 🇫🇷 Lyon 611 1903
27
Gravotechgravotech.com

Design and manufacture of engraving, marking, and cutting equipment with software and consumables for personalization and industrial applications.

Machinery Manufacturing 🇫🇷 Rillieux-la-Pape 604 n/a
28
Babolatbabolat.com

Family-owned company, racquet sports equipment supplier, expertise in strings, serving tennis, padel, badminton players worldwide since 1875.

Sporting Goods Manufacturing 🇫🇷 Lyon 589 1875
29
Acoemacoem.com

Acoem provides AI-powered sensors and data solutions to help organizations achieve a balance between progress, preservation, and conservation worldwide

Computers and Electronics Manufacturing 🇫🇷 Limonest 557 1967
30
Symbiosymbio.one

Designing and mass-producing high-performance StackPack hydrogen-electric fuel cell systems for mobility and stationary applications through specialized Gigafactory facilities in Europe and North America.

Fuel Cell Manufacturing 🇫🇷 Saint-Fons 539 2010

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How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 11, 2026.

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