These are the largest healthcare providers in Oklahoma. The list includes a mix of large integrated health systems, specialized hospitals, and government entities involved in health services. Companies like INTEGRIS Health, founded in 1994, offer comprehensive statewide services, while Saint Francis Health System, established in 1960, provides extensive care through multiple facilities in Tulsa. OU Health is a comprehensive academic health system, and Oklahoma Heart Hospital focuses on specialized cardiac care.
A notable pattern is the concentration of major healthcare organizations in Oklahoma City and Tulsa. Many of these providers, such as Norman Regional Health System (founded 1946) and Comanche County Memorial Hospital (founded 1948), have long histories, indicating established healthcare infrastructure in the state. The presence of entities like The Chickasaw Nation and Cherokee Nation highlights their role in providing health and community services.
| # | Company | Employees | |||
|---|---|---|---|---|---|
| 1 |
INTEGRIS Healthintegrishealth.org
Largest Oklahoma-owned health system offering hospitals, clinics, rehabilitation, mental health, fitness, home health, and urgent care services statewide. |
6,623 | |||
| 2 |
Saint Francis Health Systemsaintfrancis.com
Integrated health system in Tulsa offering extensive healthcare services through multiple hospitals, clinics, and specialized care centers across Oklahoma. |
4,699 | |||
| 3 |
The Chickasaw Nationchickasaw.net
A federally recognized tribe offering diverse programs and services to benefit Chickasaw families and communities through various business ventures |
4,208 | |||
| 4 |
Hillcrest HealthCare Systemhillcrest.com
Healthcare system serving northeastern Oklahoma with 9 hospitals, 2 physician groups, 6,250 employees, 322 providers, and treating nearly 150,000 patients annually |
4,055 | |||
| 5 |
OU Healthouhealth.com
Comprehensive academic health system in Oklahoma with hospitals, clinics, and specialty care, including the state's only freestanding children's hospital and cancer center |
3,571 | |||
| 6 |
Cherokee Nationcherokee.org
Sovereign tribal government with a strong focus on preserving Cherokee culture, language, and values, while also offering diverse career opportunities |
2,352 | |||
| 7 |
Norman Regional Health Systemnormanregional.com
A multi-campus health system in south central Oklahoma offering acute care, physician services, outpatient diagnostics, medical transport, and wellness services |
1,844 | |||
| 8 |
Oklahoma Heart Hospitalokheart.com
A physician-owned hospital in Oklahoma, designed by cardiologists to provide expert, individualized care with utmost comfort in a digital environment |
1,354 | |||
| 9 |
Family & Children's Servicesfcsok.org
A non-profit behavioral health clinic in metro Tulsa serving adults, children, and families by restoring wellbeing, healing abuse, and providing hope for recovery |
1,173 | |||
| 10 |
Comanche County Memorial Hospitalccmhhealth.com
Independent, non-profit acute care facility in Southwest Oklahoma, providing award-winning care with 283 beds, 2,000 employees, 250 physicians, and 100 volunteers |
1,057 | |||
| 11 |
Oklahoma Children's Hospital OU Healthouhealth.com
Innovative children's healthcare provider at OU Health, providing advanced research and treatments through hospital and outpatient services |
999 | |||
| 12 |
Crossroads Hospicecrossroadshospice.com
A national leader in hospice and palliative care, dedicated to providing innovative and compassionate support for patients and families facing serious illnesses or end-of-life care |
976 | |||
| 13 |
Stillwater Medical Centerstillwater-medical.org
A 117-bed acute care hospital in north central Oklahoma offering a wide range of medical services with a focus on quality care and patient satisfaction |
896 | |||
| 14 |
GRAND Mental Healthgrandmh.com
A mental health organization providing outpatient therapy, rehabilitation, case management, medication management, wraparound services, and support for vulnerable populations |
857 | |||
| 15 |
Ascension St. Johnhealthcare.ascension.org
Faith-based healthcare organization with hospitals, clinics, and facilities providing compassionate care to all, with special focus on persons in poverty |
805 | |||
| 16 |
SYNERGY HomeCaresynergyhomecare.com
SYNERGY HomeCare provides a range of compassionate in-home care services tailored to individuals' needs, enhancing their lives and promoting overall well-being |
773 | |||
| 17 |
Oxford HealthCareoxford-healthcare.com
A leading home healthcare provider in Tulsa offering comprehensive medical treatment and solutions for elderly and disabled individuals in the comfort of their homes |
767 | |||
| 18 |
Grady Memorial Hospital, Oklahomagradymem.org
A full-service hospital offering diagnostic, medical, surgical, and outpatient care with a 24/7 emergency center staffed by trained physicians and nurses |
654 | |||
| 19 |
Citizen Potawatomi Nationpotawatomi.org
This company is the official page of the Citizen Potawatomi Nation, representing the People of the Place of the Fire |
596 | |||
| 20 |
Our Blood Instituteobi.org
A large nonprofit blood center providing blood for patients at over 240 hospitals in Oklahoma, Arkansas, and Texas |
558 | |||
| 21 |
CareATCcareatc.com
Providing customizable healthcare solutions to employers, CareATC improves workforce health, reduces healthcare costs, and connects patients with providers efficiently |
549 | |||
| 22 |
CREOKS Health Servicescreoks.org
A provider of integrated mental health, wellness, and social services, offering comprehensive support for individuals' holistic well-being |
486 | |||
| 23 |
Bethany Children's Health Centerbethanychildrens.org
A pediatric rehabilitation hospital providing 24-hour complex care to children ages 0-21, offering inpatient and outpatient services with a multidisciplinary team |
479 | |||
| 24 |
Dental Depotdentaldepot.net
Family-owned dental practice prioritizing patient care with a focus on quality dentistry, business knowledge, and collaboration in a unique train station-themed environment |
473 | |||
| 25 |
Osage Nationosagenation-nsn.gov
A federally recognized tribe in the US, the organization works to enhance the lives of Osage people through cultural preservation and sustainable improvement initiatives |
466 | |||
Want more companies than this list?This page shows the largest ones only. Connect to Tamtam to see every company that matches, filter by size, industry or growth, and reach their decision-makers. | |||||
| 26 |
OU Health Stephenson Cancer Centerouhealth.com
A nationally recognized academic cancer center in Oklahoma conducting innovative research and providing top-notch patient care in collaboration with leading organizations |
465 | |||
| 27 |
Elder Careabouteldercare.org
A non-profit organization in Bartlesville, OK provides services for seniors and caregivers to promote healthy, independent living through various programs and support services |
434 | |||
| 28 |
Red Rock Behavioral Health Servicesred-rock.com
A nonprofit organization in Oklahoma providing integrated behavioral and physical health care to indigent and insured individuals, empowering Oklahomans to achieve better health |
431 | |||
| 29 |
OSU MEDICAL CENTER
A medical practice company located in Claremore, Oklahoma, providing healthcare services and treatments to patients in the United States |
430 | |||
| 30 |
Good Shepherd Hospicegoodshepherdhospice.com
A provider of compassionate hospice care, offering exceptional support and resources for patients, families, and staff members in multiple states |
423 | |||
| 31 |
Muscogee Nation Department of Healthcreekhealth.org
Operates hospitals, clinics, rehabilitation centers serving tribal citizens and public, expanding healthcare facilities across multiple Oklahoma locations for Native people. |
401 | |||
| 32 |
Loving Carelovingcarehealth.com
Leading home care provider in Oklahoma since 1997, offering innovative technology, data analytics, and patient-centered approach to enhance clients' lives |
400 | |||
| 33 |
Northeastern Health Systemalwaysnhs.org
Healthcare company focused on providing excellence in patient care, offering opportunities for clinical and non-clinical careers with advanced technology and innovative procedures |
391 | |||
| 34 |
Grace Living Centersgracelivingcenters.com
The company provides skilled nursing, therapy, and long-term care services in Oklahoma, with a focus on quality care and rehabilitation |
387 | |||
| 35 |
Oklahoma State University Medical Centerosumc.com
Largest osteopathic teaching hospital in Tulsa with multiple residency and fellowship programs training over 150 physicians annually. |
385 | |||
| 36 |
McAlester Regional Health Centermrhcok.com
A not-for-profit healthcare facility in McAlester, Southeastern Oklahoma, providing a wide range of medical specialties and services to the community |
383 | |||
| 37 |
St. Mary's Regional Medical Centerstmarysregional.com
A comprehensive medical center in Enid, Oklahoma offering specialized services in cardiac, neurosciences, orthopedics, women's health, emergency medicine, and rehabilitation |
378 | |||
| 38 |
The Muscogee Nationmuscogeenation.com
A self-governed Native American sovereign Nation with diverse interests in cultural tourism, business, and economic development, providing health care, social services, and education to its citizens |
375 | |||
| 39 |
Montereaumontereau.net
A locally owned, not-for-profit retirement community in Tulsa offering Independent Living, Life Care, and highly rated Short- and Long-Term Care services |
350 | |||
| 40 |
Oklahoma Surgical Hospitaloklahomasurgicalhospital.com
This hospital was founded by local physicians to prioritize patient needs and deliver high-quality, personalized medical care in a comfortable environment |
342 | |||
| 41 |
Variety Carevarietycare.org
Oklahoma's largest community health center, offering affordable and accessible primary medical, dental, vision, behavioral care, women's health, and teen services Leading the way in healthcare |
335 | |||
| 42 |
Physical Therapy Centralptcentral.org
Private physical therapy practice group in Oklahoma, focused on delivering innovative treatments and personalized care that positively impacts patients' lives |
333 | |||
| 43 |
Senior Starseniorstar.com
A family-owned company passionate about serving seniors, providing vibrant communities with personalized living and care options, and valuing their associates |
328 | |||
| 44 |
PharmcareUSApharmcareusa.com
PharmcareUSA is a pharmacy providing specialized services for Skilled, Long Term Care, and Assisted Living facilities in multiple states |
259 | |||
| 45 |
Jackson County Memorial Hospitaljcmh.com
A not-for-profit hospital in Altus, Oklahoma, offering health care services to enhance the well-being of residents, governed by a nine-member Board of Trustees |
258 | |||
| 46 |
Baptist Village Communitiesbaptistvillage.org
Provider of senior housing services in Oklahoma, offering residential living, assisted living, nursing care, rehabilitation, memory support, home healthcare, and more Residents and families benefit together |
249 | |||
| 47 |
Mental Health Association Oklahomamhaok.org
Advocacy organization supporting those with mental illness, homelessness, and substance abuse through education, counseling, referrals, and crisis response services |
233 | |||
| 48 |
Lumio Dentallumiodental.com
Modern, convenient, and comfortable dental care focused on values like patient care, teamwork, integrity, continuous improvement, and attention to detail |
227 | |||
| 49 |
OU Nursing - Life Stage Solutionsoulifestagesolutions.com
Specializing in elder care solutions, we offer collaborative assessment, coordination, education, and management of healthcare services for seniors and individuals with disabilities |
209 | |||
| 50 |
Hillcrest Hospital Southhillcrestsouth.com
A 180-bed acute care medical center in South Tulsa offering a wide range of inpatient and outpatient services, with a focus on family health |
186 | |||
Turn this list into pipeline
Tamtam finds the decision-makers at every company on a list like this one, with verified emails, phone numbers and the buying signals that tell you when to reach out.
How this list is built
Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 12, 2026.
More company lists in Oklahoma
- The largest companies in Oklahoma 714
- Oil and Gas companies in Oklahoma 112
- Energy companies in Oklahoma 103
- Critical infrastructure operators in Oklahoma 86
- Retail chains in Oklahoma 73
- Education providers in Oklahoma 70
- Manufacturers in Oklahoma 55
- Public sector organisations in Oklahoma 53
- Financial services firms in Oklahoma 51
- Multinational companies in Oklahoma 51
- Hospitals and Health Care companies in Oklahoma 44
- Companies with a mobile app in Oklahoma 41
- Hardware manufacturers in Oklahoma 40
- Companies with in-house R&D in Oklahoma 40
- Professional services firms in Oklahoma 39
- Higher Education companies in Oklahoma 35
- Family-owned companies in Oklahoma 32
- Hotel and hospitality groups in Oklahoma 30
- Government Administration companies in Oklahoma 25
- Publicly traded companies in Oklahoma 25
The same list elsewhere in United States
- Healthcare providers in the United States 5,810
- Healthcare providers in California 569
- Healthcare providers in New York State 494
- Healthcare providers in Texas 408
- Healthcare providers in Florida 361
- Healthcare providers in Pennsylvania 264
- Healthcare providers in Illinois 262
- Healthcare providers in Massachusetts 213
- Healthcare providers in Ohio 181
- Healthcare providers in Tennessee 180
- Healthcare providers in Michigan 157
- Healthcare providers in North Carolina 153
- Healthcare providers in New Jersey 151
- Healthcare providers in Georgia 148
- Healthcare providers in Washington State 136
- Healthcare providers in Colorado 126
- Healthcare providers in Alabama 124
- Healthcare providers in Indiana 123
- Healthcare providers in Arizona 122
- Healthcare providers in Virginia 121
- Healthcare providers in Minnesota 120
- Healthcare providers in Missouri 118
- Healthcare providers in Maryland 105
- Healthcare providers in New York 155