These Oklahoma companies with in-house R&D are primarily large organizations, with a strong presence in higher education and the oil and gas sector. Oklahoma State University and the University of Oklahoma, both established in 1890, are significant employers, alongside H&P, a provider of advanced drilling technologies, and Paycom, a payroll and HR software company. Other notable firms include T.D. Williamson, which offers solutions for pipeline operators, and Zeeco, Inc., a leader in combustion and environmental solutions.
A clear pattern among these companies is the prevalence of the oil and gas industry, particularly in Tulsa, which is home to H&P, T.D. Williamson, Zeeco, and John Zink. Additionally, the presence of major universities like Oklahoma State University and the University of Oklahoma highlights a strong foundation in research and development within the state.
| # | Company | Employees | |||
|---|---|---|---|---|---|
| 1 |
Oklahoma State Universitygo.okstate.edu
Delivering education, research, and community engagement in alignment with a land-grant mission for over a century |
13,451 | |||
| 2 |
University of Oklahomaou.edu
A top public university attracting students nationally and internationally, offering a private college atmosphere, academic excellence, and a wide range of fields of study |
11,872 | |||
| 3 |
H&Phelmerichpayne.com
Provider of advanced drilling technologies and solutions enhancing productivity, reliability, safety, and efficiency in land, international, and offshore operations. |
11,576 | |||
| 4 |
Paycompaycom.com
A payroll and HR software company simplifying employee life and transforming business processes with innovative technology and award-winning team |
5,731 | |||
| 5 |
T.D. Williamsontdwilliamson.com
The company provides innovative solutions for pipeline operators worldwide to maximize uptime, improve throughput, minimize risk, and address regulatory climate challenges |
1,872 | |||
| 6 |
Zeeco, Inc.zeeco.com
A global leader in combustion and environmental solutions for various industries, specializing in ultra-low emission burners, flaring systems, and waste incineration |
1,812 | |||
| 7 |
AAON, Inc.aaon.com
Innovative company advancing the HVAC industry with customizable solutions for commercial and industrial spaces, focusing on design, manufacturing, and testing |
1,654 | |||
| 8 |
NORDAMnordam.com
A global aerospace company specializing in designing, manufacturing, and maintaining propulsion systems, aircraft structures, and transparencies for business and military markets |
1,637 | |||
| 9 |
Oklahoma Heart Hospitalokheart.com
A physician-owned hospital in Oklahoma, designed by cardiologists to provide expert, individualized care with utmost comfort in a digital environment |
1,354 | |||
| 10 |
Nortek Air Solutions, LLCnortekair.com
Leading HVAC manufacturer in North America providing custom solutions for industrial air handling, cleanroom systems, and mission critical technology with extensive experience and facilities |
1,305 | |||
| 11 |
Chickasaw Nation Industries, Inc.chickasaw.com
Operating subsidiaries for federal government and commercial clients, offering solutions in various sectors, supporting Chickasaw Nation economic development. |
1,095 | |||
| 12 |
Oklahoma Children's Hospital OU Healthouhealth.com
Innovative children's healthcare provider at OU Health, providing advanced research and treatments through hospital and outpatient services |
999 | |||
| 13 |
John Zinkjohnzink.com
Global leader in environmental solutions for various industries, specializing in engineered vapor and combustion systems with Smart Combustionโข technology for optimized performance and efficiency |
869 | |||
| 14 |
ATCatcreman.com
A global leader in remanufacturing solutions for powertrain and drivetrain products for vehicles of all types, offering engineering services worldwide |
727 | |||
| 15 |
Webco Industrieswebcotube.com
A leading manufacturer and distributor of steel tubing, founded in 1969, with locations in Oklahoma, Texas, and Pennsylvania Specializing in various types of steel tubing |
699 | |||
| 16 |
Thru Tubing Solutionsthrutubing.com
Specializing in downhole operations, we offer specialized equipment and services for optimal results in shale regions worldwide, available 24/7 |
549 | |||
| 17 |
Kimray, Inckimray.com
A manufacturer based in Oklahoma City creating oil and gas control equipment since 1948 Specializing in temperature, level, flow, and pressure control solutions |
532 | |||
| 18 |
The Bama Companies, Incbama.com
Supplier of hand-held pies, biscuits, buns, pie shells, and pizza crusts to major restaurant chains worldwide with custom oven-ready products. |
486 | |||
| 19 |
AMETEK MROametekmro.com
Global provider of third-party MRO services for commercial, regional, and general aviation Specializing in repair and overhaul services with various approvals |
481 | |||
Want more companies than this list?This page shows the largest ones only. Connect to Tamtam to see every company that matches, filter by size, industry or growth, and reach their decision-makers. | |||||
| 20 |
OU Health Stephenson Cancer Centerouhealth.com
A nationally recognized academic cancer center in Oklahoma conducting innovative research and providing top-notch patient care in collaboration with leading organizations |
465 | |||
| 21 |
Summit ESPsummitesp.com
A service provider offering integrated Electric Submersible Pumping systems to optimize production, reduce costs, and increase profitability in the artificial lift industry |
448 | |||
| 22 |
BS&B Safety Systemsbsbsystems.com
Global leader in non-reclosing pressure relief devices, setting industry standards with innovative products and services to protect personnel and equipment worldwide |
442 | |||
| 23 |
Page Not Active - H&P Technologieshpinc.com
A division of H&P, find us on LinkedIn under the handle @Helmerich-Payne for more information |
431 | |||
| 24 |
OU Health Campus Graduate Collegegraduate.ouhsc.edu
Networking platform for currently enrolled students and alumni of The University of Oklahoma Health Sciences Center Graduate College to connect and stay updated on activities |
361 | |||
| 25 |
Jasco Productsbyjasco.com
Jasco designs and develops innovative home automation, lighting, security, entertainment, power, and mobility products for global distribution through major retailers and online platforms |
361 | |||
| 26 |
PCI Energy Solutionspcienergysolutions.com
A team of experts creates software solutions for power generation companies, optimizing efficiency, reducing costs, and promoting a cleaner energy future |
358 | |||
| 27 |
McElroy Manufacturing, Inc.mcelroy.com
Established in 1954, this company specializes in engineering and manufacturing fusion equipment for thermoplastic pipes, leading the industry with technological advancements |
335 | |||
| 28 |
MIRATECHmiratechcorp.com
Industry leader providing emission and acoustical solutions for engines, helping customers meet regulatory requirements while reducing emissions complexity Engineered for performance and quality |
325 | |||
| 29 |
Enovation Controlsenovationcontrols.com
Innovator of electronic controls and displays, providing customized solutions for engines, engine-driven equipment, and specialty vehicles across diverse markets globally. |
265 | |||
| 30 |
Noble Research Institutenoble.org
A company dedicated to promoting regenerative ranching principles to transform grazing lands and benefit the environment while supporting producers' bottom line |
262 | |||
| 31 |
Wolverine Tube, Inc.wlv.com
A global leader in innovative heat transfer solutions, specializing in thermal management products for various industries worldwide with a focus on energy efficiency and tailored customer solutions |
187 | |||
| 32 |
Mercer Valve Co., Inc.mercervalve.net
A company focused on delivering high-quality pressure relief valves with patented technology, competitive pricing, timely delivery, and professional services |
186 | |||
| 33 |
Field Aerospacefieldaero.com
Field Aerospace in Oklahoma City offers aircraft modifications, maintenance, project management, and integration services for special mission aircraft and avionics systems |
143 | |||
| 34 |
Da/Pro Rubber, Inc.daprorubber.com
Specializing in molding high-quality components since 1960, providing expert assistance in rubber, plastic, and TPE molding with ISO-certified facilities |
124 | |||
| 35 |
DMI International, LLC.dmiinternational.com
Manufacturer and supplier of construction and maintenance equipment for the pipeline industry, offering quality products, engineering expertise, and world class service globally |
53 | |||
| 36 |
Walvoil Fluid Power USAwalvoilusa.com
Global manufacturer of hydraulic valves, pumps, motors, and mechatronic systems for various industries, providing integrated hydraulic and electronic solutions for major OEMs worldwide |
43 | |||
| 37 |
SISU Energy and Environmentalsisu-ee.com
A solutions-driven partner specializing in emissions reduction, retrofit optimization, field service, waste heat recovery, renewables, and distributed energy for sustainable projects |
35 | |||
| 38 |
CMI ROADBUILDING INC.cmi-roadbuilding.com
A heavy equipment manufacturing company specializing in road building, construction, and waste management Offers products for compaction, paving, and recycling |
33 | |||
| 39 |
Ascend Beyond Spaceascendbeyond.space
Democratizing end-of-life management and disposal of satellites with a complete and accessible ecosystem for sustainable space debris solutions. |
4 | |||
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Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 11, 2026.
More company lists in Oklahoma
- The largest companies in Oklahoma 714
- Oil and Gas companies in Oklahoma 112
- Energy companies in Oklahoma 103
- Critical infrastructure operators in Oklahoma 86
- Retail chains in Oklahoma 73
- Education providers in Oklahoma 70
- Healthcare providers in Oklahoma 57
- Manufacturers in Oklahoma 55
- Public sector organisations in Oklahoma 53
- Financial services firms in Oklahoma 51
- Multinational companies in Oklahoma 51
- Hospitals and Health Care companies in Oklahoma 44
- Companies with a mobile app in Oklahoma 41
- Hardware manufacturers in Oklahoma 40
- Professional services firms in Oklahoma 39
- Higher Education companies in Oklahoma 35
- Family-owned companies in Oklahoma 32
- Hotel and hospitality groups in Oklahoma 30
- Government Administration companies in Oklahoma 25
- Publicly traded companies in Oklahoma 25
The same list elsewhere in United States
- Companies with in-house R&D in the United States 6,796
- Companies with in-house R&D in California 1,276
- Companies with in-house R&D in Texas 442
- Companies with in-house R&D in New York State 419
- Companies with in-house R&D in Massachusetts 396
- Companies with in-house R&D in Illinois 322
- Companies with in-house R&D in Michigan 287
- Companies with in-house R&D in Ohio 277
- Companies with in-house R&D in Pennsylvania 255
- Companies with in-house R&D in New Jersey 224
- Companies with in-house R&D in Florida 221
- Companies with in-house R&D in Alabama 214
- Companies with in-house R&D in Georgia 173
- Companies with in-house R&D in Virginia 166
- Companies with in-house R&D in North Carolina 158
- Companies with in-house R&D in Wisconsin 154
- Companies with in-house R&D in Minnesota 146
- Companies with in-house R&D in Washington State 140
- Companies with in-house R&D in Colorado 113
- Companies with in-house R&D in Maryland 107
- Companies with in-house R&D in Indiana 104
- Companies with in-house R&D in New York 223
- Companies with in-house R&D in San Francisco 147
- Companies with in-house R&D in Houston 129