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100 leading companies with in-house R&D in Pennsylvania

Tamtam tracks 255 companies with in-house R&D headquartered in Pennsylvania. This list ranks the 100 largest by number of employees on LinkedIn, led by Comcast, UPMC and PPG. Their median headcount is 3,489. Half of them were founded in 1946 or later. The most common headquarters are Pittsburgh (21), Philadelphia (18) and Allentown (5).

๐Ÿ‡บ๐Ÿ‡ธ Pennsylvania100 companiesUpdated Nov 11, 2026

These large organizations in Pennsylvania engage in in-house research and development across diverse sectors. Comcast delivers broadband and entertainment, UPMC provides healthcare and insurance, PPG develops paints and coatings, and Penn State University offers interdisciplinary education. Other notable companies include Wabtec Corporation, which supplies rail equipment, and Air Products, a global supplier of industrial gases.

The data reveals a strong concentration of R&D activities in the state's major cities. A significant number of these large companies are either headquartered in Philadelphia or Pittsburgh, with several prominent universities and healthcare systems also located in these urban centers. The presence of both long-established companies, like PPG (founded 1883), and more recent ventures, highlights a varied historical footprint.

#CompanyIndustryHeadquarters EmployeesFounded
1
Comcastcomcast.com

Delivering broadband, mobile, and video products, along with entertainment, sports, news, and theme park experiences; driven by passionate creators and innovators

Telecommunications ๐Ÿ‡บ๐Ÿ‡ธ Philadelphia 189,000 1963
2
UPMCupmc.com

A leading health care provider and insurer in Pittsburgh, offering patient-centered care, innovative models, and community benefits through hospitals and insurance services

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Pittsburgh 41,860 n/a
3
PPGppg.com

Development and delivery of paints, coatings, and specialty materials serving construction, consumer products, industrial, transportation, and aftermarket markets worldwide.

Paint, Coating, and Adhesive Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Pittsburgh 33,277 1883
4
Penn State Universitypsu.edu

Providing interdisciplinary education and resources across multiple campuses, fostering student success and positive global community impact through knowledge and experience.

Higher Education ๐Ÿ‡บ๐Ÿ‡ธ University Park 31,986 1855
5
Wabtec Corporationwabteccorp.com

Provider of equipment, systems, digital solutions, and services for freight rail, transit, mining, industrial, and marine transportation sectors.

Railroad Equipment Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Pittsburgh 27,000 1869
6
University of Pennsylvaniaupenn.edu

Renowned Ivy League university with 12 schools offering a wide range of programs including arts, sciences, engineering, business, and medicine

Higher Education ๐Ÿ‡บ๐Ÿ‡ธ Philadelphia 22,558 1740
7
Penn Medicine, University of Pennsylvania Health Systempennmedicine.org

Leading academic medical center combining cutting-edge research, comprehensive patient care, and education to improve health and transform lives regionally.

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Philadelphia 21,979 n/a
8
Air Productsairproducts.com

Supplier of industrial gases serving over 250,000 customers in more than 50 countries worldwide with diverse applications.

Chemical Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Allentown 20,000 1940
9
University of Pittsburghpitt.edu

Top-ranked public institution in Pennsylvania, member of leading research universities Known for innovative discoveries and shaping future paths

Higher Education ๐Ÿ‡บ๐Ÿ‡ธ Pittsburgh 19,349 1787
10
Children's Hospital of Philadelphiachop.edu

Specialized pediatric hospital providing exceptional patient care, pioneering medical research, and training future pediatric healthcare professionals.

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Philadelphia 18,042 1855
11
Viatrisviatris.com

Global healthcare company providing extensive medicine portfolio and supply chain to deliver high-quality medicines addressing diverse health needs worldwide.

Pharmaceutical Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Pittsburgh 17,886 n/a
12
Geisingergeisinger.org

Healthcare organization with 13 hospital campuses, research centers, medical college, and health plan serving millions in Pennsylvania Committed to quality healthcare

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Danville 15,962 1915
13
Mylanviatris.com

Empowering people worldwide to live healthier at every stage of life through a merger with Upjohn, now known as Viatris

Pharmaceutical Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Canonsburg 15,198 n/a
14
Temple Universitytemple.edu

A top-tier research institution in a vibrant city, offering diverse degree programs to prepare future leaders for impactful careers

Higher Education ๐Ÿ‡บ๐Ÿ‡ธ Philadelphia 13,124 1884
15
FMC Corporationfmc.com

The company is dedicated to innovating sustainable technologies to protect crops, support farmers, and tackle agriculture's challenges using science

Agricultural Chemical Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Philadelphia 11,986 1883
16
Allegheny Health Networkahn.org

Integrated healthcare delivery system with hospitals, medical centers, wellness pavilions, and numerous physician practices serving Western Pennsylvania.

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Pittsburgh 11,676 n/a
17
The Hershey Companythehersheycompany.com

Leading global snacks company producing iconic confectionery brands, committed to quality products, community support, and educational initiatives.

Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Hershey 11,057 1894
18
Teleflexteleflex.com

Provides diverse medical technologies and solutions across various therapy areas, improving health and quality of life for people worldwide through purpose-driven innovation.

Medical Equipment Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Wayne 9,909 1943
19
Penn State Healthpennstatehealth.org

Multi-hospital health system in central Pennsylvania with medical centers, outpatient practices, and a partnership with Highmark Health for community care

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Hershey 8,037 1963
20
Axaltaaxalta.com

A global provider of performance coatings for industrial, automotive, and refinish applications, focused on innovation for a sustainable future

Chemical Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Philadelphia 7,744 2013
21
B. Braun Medical Inc. (US)bbraunusa.com

A global healthcare leader specializing in infusion therapy, pain management, nutrition, pharmacy admixture, and dialysis products and services Committed to safety and innovation

Medical Equipment Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Bethlehem 7,619 1839
22
Drexel Universitydrexel.edu

Academically comprehensive urban research university with a globally engaged community and a premier cooperative education program nationwide.

Higher Education ๐Ÿ‡บ๐Ÿ‡ธ Philadelphia 7,580 1891
23
Howmet Aerospacehowmet.com

A global provider of advanced engineered solutions for aerospace and transportation industries, specializing in jet engine components, aerospace fastening systems, and titanium structural parts

Aviation and Aerospace Component Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Pittsburgh 7,402 2020
24
Coherent Corp.coherent.com

Development and delivery of breakthrough technologies and innovations for industrial, communications, electronics, and instrumentation market applications worldwide.

Semiconductor Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Saxonburg 7,389 1971
25
Clarioclario.com

A leading healthcare research and technology company providing expertise and technology for advancing clinical trials in various therapeutic areas worldwide

Biotechnology Research ๐Ÿ‡บ๐Ÿ‡ธ Philadelphia 7,151 1972
26
PPL Corporationpplweb.com

Providing electricity to millions, building smarter, resilient power grids, advancing sustainable energy solutions, and fostering inclusive work environments.

Utilities ๐Ÿ‡บ๐Ÿ‡ธ Allentown 7,118 1920
27
United States Steel Corporationussteel.com

Developing and delivering profitable, next-generation steel solutions focused on safety and meeting current and future customer needs.

Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Pittsburgh 6,794 1901
28
Kennametalkennametal.com

A global industrial technology leader specializing in advanced materials innovation, tooling, and wear-resistant solutions to enhance productivity for various industries

Machinery Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Pittsburgh 6,659 n/a
29
Ansysansys.com

Delivering silicon design breakthroughs and IP to enable rapid innovation of AI-powered products across multiple high-tech industries.

Software Development ๐Ÿ‡บ๐Ÿ‡ธ Canonsburg 6,283 1970
30
West Pharmaceutical Serviceswestpharma.com

provider of high-quality injectable components and devices ensuring safe, effective delivery and containment of medicines worldwide

Pharmaceutical Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Exton 6,268 1923
31
EnerSysenersys.com

Global leader in stored energy solutions for industrial applications, offering motive power, reserve power, aerospace/defense, specialty batteries, and integrated services worldwide

Appliances, Electrical, and Electronics Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Reading 6,257 n/a
32
AMETEKametek.com

Global provider of industrial technology solutions with over $60 billion in annual sales, serving niche markets with differentiated technology solutions and focused on shareholder value generation

Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Berwyn 5,963 1930
33
Crown Holdings, Inc.crowncork.com

Design manufacture and sale of steel and aluminum cans, glass bottles, closures, and industrial packaging products and equipment worldwide.

Packaging and Containers Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Yardley 5,891 1892
34
Temple Health โ€“ Temple University Health Systemtemplehealth.org

Temple Health provides advanced research and clinical care, offering innovative treatments through renowned physicians, nurses, and researchers in various medical facilities and practices

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Philadelphia 5,770 1892
35
Thomas Jefferson Universityjefferson.edu

University focused on innovative health education, interdisciplinary learning, expert faculty collaboration, and redefining possibilities in health, education, and discovery.

Higher Education ๐Ÿ‡บ๐Ÿ‡ธ Philadelphia 5,700 1824
36
Bentley Systemsbentley.com

Innovative software for infrastructure engineering, design, construction, and operations, advancing global economy and environment with industry-leading solutions in multiple sectors worldwide

Software Development ๐Ÿ‡บ๐Ÿ‡ธ Exton 5,633 1984
37
Vishay Intertechnology, Inc.vishay.com

Manufactures extensive range of discrete semiconductors and passive electronic components for automotive, industrial, computing, consumer, telecom, military, aerospace, and medical markets worldwide.

Appliances, Electrical, and Electronics Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Malvern 5,426 n/a
38
PCI Pharma Servicespci.com

Provides world-class solutions for drug development, manufacturing, advanced drug delivery, clinical trials, and commercial packaging, delivering life-changing therapies globally.

Pharmaceutical Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Philadelphia 4,795 n/a
39
Olympus Corporation of the Americasolympusamerica.com

A global medical technology company partnering with healthcare professionals to provide solutions for early detection, diagnosis, and minimally invasive treatment

Medical Equipment Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Center Valley 4,752 n/a
40
Arconicarconic.com

A leading provider of aluminum products for automotive, aerospace, transportation, industrial, packaging, and construction markets, committed to innovation and advancement

Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Pittsburgh 4,672 2016
41
Qlikqlik.com

Delivers trusted data products, powerful analytics engines, and AI agents helping teams scale responsibly while reducing risk and maintaining flexible system integration.

Software Development ๐Ÿ‡บ๐Ÿ‡ธ King of Prussia 4,561 1993
42
MSA - The Safety Companymsasafety.com

Designs and manufactures advanced safety products and technologies protecting workers and infrastructure worldwide across diverse industries.

Public Safety ๐Ÿ‡บ๐Ÿ‡ธ Cranberry Township 4,260 1914
43
Naval Nuclear Laboratory (FMP)navalnuclearlab.energy.gov

The company operates the Naval Nuclear Laboratory, supporting the US Naval Nuclear Propulsion Program through research, development, training, and technical support

Defense and Space Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ West Mifflin 3,940 1946
44
TRIUMPHtriumphgroup.com

Design, engineering, manufacturing, repair, and overhaul of aviation and industrial components, partnering with OEMs and operators globally.

Aviation and Aerospace Component Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Radnor 3,933 1993
45
Susquehanna International Groupsig.com

global proprietary trading firm providing liquidity, competitive pricing, quantitative strategies, private equity, structured capital, and institutional brokerage services

Financial Services ๐Ÿ‡บ๐Ÿ‡ธ Bala Cynwyd 3,913 1987
46
Graham Packaginggrahampackaging.com

A leader in sustainable packaging design, manufacturing, and sales for food, beverage, household, and automotive industries with global reach

Packaging and Containers Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Lancaster 3,562 1970
47
Quaker Houghtonhome.quakerhoughton.com

Global leader in industrial process fluids, serving advanced manufacturing industries with expertise in chemistry and engineering for efficient operations and future growth

Chemical Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Conshohocken 3,523 n/a
48
CertainTeedcertainteed.com

A leading provider of sustainable exterior and interior building products in North America, with a focus on innovation and environmental responsibility

Wholesale Building Materials ๐Ÿ‡บ๐Ÿ‡ธ Malvern 3,511 1904
49
Crane Payment Innovationscranepi.com

Provides world-class, automated payment solutions and experiences, developing products in currency validation, cash management, digital payment, mobile apps, and security for global consumers.

Appliances, Electrical, and Electronics Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Malvern 3,504 n/a
50
UPMC Children's Hospital of Pittsburghchp.edu

A leader in treating childhood conditions, developing therapies, educating pediatricians, and advancing research with strong community support since 1890

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Pittsburgh 3,489 1890

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51
Globus Medicalglobusmedical.com

Development and manufacturing of innovative orthopedic surgical products focused on improving patient outcomes and enabling pain-free, active lives.

Medical Equipment Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Audubon 3,451 2003
52
Eurofins Lancaster Laboratorieseurofinsus.com

A global contract laboratory providing comprehensive services in pharmaceutical, biopharmaceutical, and environmental sciences to a diverse range of clients worldwide

Biotechnology Research ๐Ÿ‡บ๐Ÿ‡ธ Lancaster 3,426 1961
53
Victaulicvictaulic.com

A global leader in pipe joining and flow control solutions for construction projects, offering innovative products and technologies for increased system durability

Industrial Machinery Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Easton 3,373 1919
54
SunGard - now part of FISfisglobal.com

Financial technology company offering updates and news through LinkedIn and FISGlobalcom after acquiring SunGard

IT Services and IT Consulting ๐Ÿ‡บ๐Ÿ‡ธ Wayne 3,348 1968
55
Lutron Electronicslutron.com

Design and manufacture innovative lighting, shading, and control systems to enhance everyday experiences through transformative light technology.

Appliances, Electrical, and Electronics Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Coopersburg 3,347 1961
56
Boeing Defense, Space & Securityboeing.com

A division of a leading company focusing on defense and aerospace products and services, based in Arlington, Virginia Formerly known as Boeing Integrated Defense Systems

Business Consulting and Services ๐Ÿ‡บ๐Ÿ‡ธ Wayne 3,334 2002
57
Carpenter Technology Corporationcarpentertechnology.com

Producer and distributor of premium specialty alloys and advanced materials for aerospace, transportation, medical, energy, and additive manufacturing applications.

Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Philadelphia 3,271 1889
58
Armstrong World Industriesarmstrongceilings.com

Design and manufacture innovative ceiling and wall systems enhancing aesthetics, acoustics, well-being, and sustainability in various interior spaces.

Wholesale Building Materials ๐Ÿ‡บ๐Ÿ‡ธ Lancaster 3,186 1860
59
Excelitas Technologies Corp.excelitas.com

Provider of advanced photonic technologies specializing in sensing, detection, imaging, optics, and specialty illumination for diverse global industries.

Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Pittsburgh 3,129 n/a
60
JLG Industriesjlg.com

Manufacturing mobile elevating work platforms, telehandlers, utility vehicles, and accessories for construction and industrial safety worldwide.

Machinery Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ McConnellsburg 3,052 1969
61
Boomiboomi.com

The company offers a platform for intelligent connectivity and automation, enabling seamless connections between people and devices regardless of location

Software Development ๐Ÿ‡บ๐Ÿ‡ธ Conshohocken 3,030 2000
62
Auroraaurora.tech

Aurora provides self-driving technology for transportation, making it safer, more accessible, and efficient for various vehicle types and industries

Software Development ๐Ÿ‡บ๐Ÿ‡ธ Pittsburgh 2,568 2017
63
Matthews Internationalmatw.com

Global provider of precision industrial technologies and memorialization products, serving industries and funeral homes with innovative, efficient solutions.

Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Pittsburgh 2,226 1850
64
Dorman Productsdormanproducts.com

Manufacture and supply aftermarket automotive, heavy-duty, and specialty vehicle replacement parts designed to save time, money, and increase reliability.

Motor Vehicle Parts Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Colmar 2,210 1918
65
University of Pittsburgh School of Medicinemedschool.pitt.edu

Training physician leaders and scientists to improve health, advance research, promote equity, and collaborate internationally in medicine and education.

Higher Education ๐Ÿ‡บ๐Ÿ‡ธ Pittsburgh 2,199 1886
66
Fox Chase Cancer Centerfoxchase.org

Dedicated cancer hospital with expert multidisciplinary teams advancing prevention, diagnosis, treatment, and survivorship through pioneering research and clinical care.

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Philadelphia 2,146 1904
67
DDI | Development Dimensions Internationalddiworld.com

Global leadership consulting firm assisting organizations with hiring, promotion, and development of exceptional leaders from first-time managers to senior C-suite executive levels.

Human Resources Services ๐Ÿ‡บ๐Ÿ‡ธ Bridgeville 2,120 1970
68
Trinseotrinseo.com

A specialty material solutions provider partnering with companies to innovate and create sustainable products across various industries worldwide

Chemical Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Wayne 2,009 n/a
69
Drexel University College of Medicinedrexel.edu

A prestigious medical school offering MD and graduate programs, committed to diversity and excellence in medical education and research

Higher Education ๐Ÿ‡บ๐Ÿ‡ธ Philadelphia 1,935 2002
70
Industrial Coatingsppg.com

Global provider of advanced coatings, paints, and specialty materials focused on protecting and enhancing industrial products and landmarks.

Wholesale Building Materials ๐Ÿ‡บ๐Ÿ‡ธ Pittsburgh 1,830 n/a
71
Southco, Inc.southco.com

Global leader in engineered access solutions for transportation, industrial, medical, and data center applications, with innovative products and a dedicated global team serving customers worldwide

Industrial Machinery Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Concordville 1,720 1899
72
Crayolacrayola.com

A leading art product company inspiring creativity in children globally, promoting diversity, inclusion, and sustainability in its operations and products

Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Easton 1,687 1903
73
Ebara Elliott Energyelliott-turbo.com

Designs and manufactures centrifugal compressors, steam turbines, pumps, and cryogenic products for petrochemical, refining, oil and gas industries.

Industrial Machinery Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Jeannette 1,644 1910
74
Certaracertara.com

This company accelerates medicine development by using biosimulation software, technology, and services to revolutionize drug discovery and development globally

Business Consulting and Services ๐Ÿ‡บ๐Ÿ‡ธ Radnor 1,514 n/a
75
Sharp Servicessharpservices.com

Provides commercial packaging, clinical services, and sterile manufacturing for pharmaceutical and biotech clients, covering R&D to market launch globally.

Pharmaceutical Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Allentown 1,506 1993
76
TestingXpertstestingxperts.com

A global leader in Quality Engineering and Digital Assurance services, offering a comprehensive range of testing solutions for Next Gen technologies

IT Services and IT Consulting ๐Ÿ‡บ๐Ÿ‡ธ Mechanicsburg 1,480 2013
77
SK pharmtecoskpharmteco.com

Global contract development and manufacturing organization for active pharmaceutical ingredients, advanced intermediates, and cell and gene therapy for the pharmaceutical industry.

Pharmaceutical Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Rancho Cordova 1,433 n/a
78
FXIfxi.com

A leading producer of innovation for various markets, creating products for home, healthcare, electronics, personal care, transportation, and industrial applications

Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Radnor 1,408 n/a
79
Vishay Precision Group, Inc. (VPG)vpgsensors.com

A global leader in precision measurement sensing technologies, focusing on accuracy, reliability, and repeatability for various applications worldwide

Appliances, Electrical, and Electronics Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Malvern 1,334 2010
80
Aquatechaquatech.com

Global leader in water technology, specializing in desalination, water reuse, and zero liquid discharge solutions to reduce water and carbon footprint worldwide

Environmental Services ๐Ÿ‡บ๐Ÿ‡ธ Canonsburg 1,270 1981
81
Greene Tweedgtweed.com

Global manufacturer of high-performance thermoplastics, composites, seals, and engineered components for industries like semiconductor, oil & gas, aerospace, defense, and pharmaceutical processing

Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Lansdale 1,238 1863
82
Colorconcolorcon.com

Develops, supplies, and supports formulated film coating systems, modified release technologies, core excipients, and functional packaging for the pharmaceutical industry.

Pharmaceutical Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Harleysville 1,228 1961
83
Concurrent Technologies Corporationctc.com

Independent nonprofit organization providing applied scientific research, development, testing, prototyping, and innovative solutions supporting national security and American manufacturing.

Defense and Space Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Johnstown 1,134 1987
84
Madrigal Pharmaceuticalsmadrigalpharma.com

Clinical-stage biopharmaceutical company developing novel therapeutics for NASH, focusing on thyroid hormone receptor agonist to target underlying causes in the liver

Pharmaceutical Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Conshohocken 1,133 2016
85
Koppers Inc.koppers.com

A global wood preservation technology company creating environmentally responsible solutions for various industries, with a focus on safety and sustainability

Chemical Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Pittsburgh 1,080 1988
86
Software Engineering Institute | Carnegie Mellon Universitysei.cmu.edu

The company conducts research on software engineering, cybersecurity, and AI, creating and testing innovative technologies for government and private industry since 1984

Software Development ๐Ÿ‡บ๐Ÿ‡ธ Pittsburgh 1,061 1984
87
Tobyhanna Army Depottobyhanna.army.mil

Leader in logistics support for military C5ISR systems, offering sustainment, overhaul, manufacturing, engineering, integration, and field support for the Department of Defense

Armed Forces ๐Ÿ‡บ๐Ÿ‡ธ Tobyhanna 1,046 1953
88
Talogytalogy.com

Experts in talent management crafting solutions for screening, selecting, developing, and engaging talent worldwide using psychology and technology for data-driven decisions

Human Resources Services ๐Ÿ‡บ๐Ÿ‡ธ Pittsburgh 1,036 1946
89
Spark Therapeutics, Inc.sparktx.com

Leading gene therapy company focused on treating inherited diseases through innovative science, integrated expertise, and commitment to accelerating healthcare transformation globally

Biotechnology Research ๐Ÿ‡บ๐Ÿ‡ธ Philadelphia 1,035 2013
90
TIMETtimet.com

A leading producer of titanium melted and mill products for various industries worldwide, offering a wide range of high-quality titanium products

Mining ๐Ÿ‡บ๐Ÿ‡ธ Pittsburgh 1,028 1950
91
Temple University - Lewis Katz School of Medicinetemple.edu

Leading medical school offering humanistic education, top clinical training, and groundbreaking research, recognized internationally, honored nationally, and essential locally

Higher Education ๐Ÿ‡บ๐Ÿ‡ธ Philadelphia 1,015 n/a
92
Good Shepherd Rehabilitationgoodshepherdrehab.org

A not-for-profit rehabilitation network offering inpatient, outpatient, and community-based services for patients of all ages and abilities in eastern PA and NJ

Hospitals and Health Care ๐Ÿ‡บ๐Ÿ‡ธ Allentown 1,004 1908
93
EXALTA Groupexalta.com

Global provider of manufacturing and integrated OEM solutions supporting leading MedTech companies in delivering innovative medical devices worldwide.

Medical Equipment Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Bethlehem 995 2012
94
Lake Erie College of Osteopathic Medicine (LECOM)lecom.edu

Training future healthcare professionals in osteopathy, pharmacy, dentistry, and podiatry with a focus on innovation, excellence, and affordability

Higher Education ๐Ÿ‡บ๐Ÿ‡ธ Erie 956 1992
95
Clair Globalclairglobal.com

A tech company specializing in live production services and integrated permanent solutions for events

Entertainment Providers ๐Ÿ‡บ๐Ÿ‡ธ Lititz 943 1966
96
Federal Reserve Bank of Philadelphiaphiladelphiafed.org

Implement monetary policy, supervise banks, provide financial services to institutions and government One of 12 regional Reserve Banks in Federal Reserve System

Financial Services ๐Ÿ‡บ๐Ÿ‡ธ Philadelphia 852 1914
97
PennEngineeringยฎpemnet.com

A global leader in engineered fastening, installation, and wire protection solutions with in-house technical engineering experts worldwide since 1942

Machinery Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Danboro 840 1942
98
HarbisonWalker Internationalthinkhwi.com

A global leader in refractory products delivering solutions to industries worldwide with over 150 years of excellence in performance and value

Glass, Ceramics and Concrete Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Pittsburgh 809 2000
99
Minaris Advanced Therapiesminaris.com

Global cell and gene therapy CDMO and biosafety testing provider with deep experience supporting therapeutic programs from IND through commercial supply.

Pharmaceutical Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Tokyo 808 2025
100
Fullerfuller-technologies.com

Providing pioneering cement technologies, reliable services, and expertise to help producers operate sustainably and improve performance worldwide.

Industrial Machinery Manufacturing ๐Ÿ‡บ๐Ÿ‡ธ Allentown 786 1882

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Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 11, 2026.

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