These New York companies with in-house R&D are primarily large groups, with significant representation in financial services and healthcare. Key players include Pfizer, a biopharmaceutical company; American Express, a global payments company; Goldman Sachs, a financial institution; and The Estée Lauder Companies Inc., a leader in personal care products. Other notable firms are WNS, providing digital business transformation, and BNY, a global financial platforms provider.
The data shows a strong concentration of established enterprises, with many founded before the 21st century. For example, BNY was founded in 1784 and Columbia University in 1754. This indicates a long history of corporate presence and research and development activities in New York.
| # | Company | Employees | |||
|---|---|---|---|---|---|
| 1 |
Pfizerpfizer.com
A leading biopharmaceutical company focused on research and innovation to develop therapies that improve and extend the lives of patients worldwide |
102,598 | |||
| 2 |
American Expressamericanexpress.com
A globally integrated payments company supporting customers' financial confidence, promoting commerce, and providing experiences that enrich lives and drive business success |
94,909 | |||
| 3 |
Goldman Sachsgoldmansachs.com
Global financial institution providing expert capital markets services, investment banking, and asset management for clients through partnership, integrity, and world-class operational excellence. |
76,000 | |||
| 4 | 61,367 | ||||
| 5 |
The Estée Lauder Companies Inc.elcompanies.com
A global leader in skincare, makeup, fragrance, and hair care, offering luxury brands sold in 150+ countries, with a diverse product portfolio |
60,000 | |||
| 6 | 55,654 | ||||
| 7 |
Compasscompass.com
Real estate technology company with a platform supporting the buying and selling process, delivering exceptional experiences for agents and clients |
35,116 | |||
| 8 |
BlackRockblackrock.com
Global asset manager and technology provider helping people invest through diverse market access and expert financial insights across more than forty countries. |
34,599 | |||
| 9 |
Colgate-Palmolivecolgatepalmolive.com
Develops, produces, distributes, and sells essential health & hygiene products and pet nutrition offerings, with a focus on sustainability and community wellbeing. |
30,816 | |||
| 10 |
Mount Sinai Health Systemmountsinai.org
Provides distinguished care, conducts transformative research, and advances biomedical education through hospitals, a medical school, and extensive ambulatory network. |
30,202 | |||
| 11 |
NYU Langone Healthjobs.nyulangone.org
World-class academic medical center with top-ranked patient care, education, and research programs, serving diverse communities with excellence and inclusive values |
29,840 | |||
| 12 |
Nielsennielsen.com
Global leader in audience insights, data, and analytics shaping media and content by understanding behaviors across all platforms, empowering clients with actionable intelligence |
29,147 | |||
| 13 |
Bloombergbloomberg.com
Global provider of real-time financial data, market information, and news, leveraging technology and analysis to support financial decision-making worldwide. |
26,832 | |||
| 14 |
Columbia Universitycolumbia.edu
A renowned leader in higher education, Columbia attracts top minds to drive academic inquiry, make groundbreaking discoveries, and serve society globally |
23,565 | |||
| 15 | 22,222 | ||||
Want more companies than this list?This page shows the largest ones only. Connect to Tamtam to see every company that matches, filter by size, industry or growth, and reach their decision-makers. | |||||
| 16 | 22,000 | ||||
| 17 |
Ralph Laurencorporate.ralphlauren.com
Global leader in luxury lifestyle products across apparel, footwear, accessories, home, fragrances, and hospitality, inspiring timeless style and authenticity for over 50 years |
21,641 | |||
| 18 |
Memorial Sloan Kettering Cancer Centermskcc.org
Specialized teams provide personalized cancer care, conduct innovative research, and train future scientists and clinicians worldwide. |
19,653 | |||
| 19 |
Broadridgebroadridge.com
Provide technology and operations platforms supporting financial services, processing communications, enabling trading, and enhancing investor experiences worldwide. |
17,674 | |||
| 20 |
Hospital for Special Surgeryhss.edu
Academic medical center specializing in orthopedics and rheumatology with top national rankings, low complication rates, and multiple regional facilities. |
17,614 | |||
| 21 |
L3 Technologiesl3harris.com
Develops advanced defense technologies and commercial solutions in pilot training, aviation security, night vision, weapons, maritime systems and space for worldwide deployment. |
15,734 | |||
| 22 | 15,308 | ||||
| 23 |
Moody's Corporationmoodys.com
Global risk assessment firm providing data, analytics, and insights to empower organizations in making informed decisions and managing business risks worldwide |
15,249 | |||
| 24 |
Gapgapinc.com
Iconic global retailer specializing in denim and elevated American style clothing across fourteen hundred stores worldwide with a focus on community and diversity. |
15,202 | |||
| 25 |
Synechronsynechron.com
Innovative consulting firm leveraging digital technology to deliver leading solutions in AI, digital, cloud, data, and software engineering for financial services and technology industries globally |
14,671 | |||
| 26 |
Tiffany & Co.tiffany.com
Luxury jewelry and accessories company founded in 1837, known for innovative design, fine craftsmanship, and global cultural influence Operates worldwide |
14,000 | |||
| 27 |
Cliniqueclinique.com
A leading skincare and makeup brand founded by dermatologists, offering clinically proven, allergy-tested solutions for remarkable skin results worldwide |
11,697 | |||
| 28 |
Moody's Analyticsmoodys.com
Financial intelligence and analytical tools provider empowering clients to make better decisions through expertise in risk, information resources, and innovative technology solutions |
11,588 | |||
| 29 |
Datadogdatadoghq.com
Provider of essential monitoring platform for cloud applications, consolidating data from various sources to ensure optimal performance and user experience for DevOps teams |
10,888 | |||
| 30 |
Weill Cornell Medicinecareers.weill.cornell.edu
A leading medical institution in NYC, conducting cutting-edge research, providing top-notch patient care, and educating future physicians and scientists worldwide |
10,471 | |||
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How this list is built
Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 11, 2026.
More company lists in New York
- The largest companies in New York 8,171
- Multinational companies in New York 1,836
- Financial services firms in New York 995
- SaaS companies in New York 958
- Financial Services companies in New York 885
- Professional services firms in New York 735
- Venture capital and private equity firms in New York 727
- Software Development companies in New York 612
- AI companies in New York 543
- Subscription businesses in New York 422
- Investment Management companies in New York 421
- Real Estate companies in New York 417
- Marketing and communications agencies in New York 389
- Advertising Services companies in New York 387
- IT Services and IT Consulting companies in New York 387
- Companies with a mobile app in New York 371
- Venture Capital and Private Equity Principals companies in New York 370
- Consulting firms in New York 368
- Retail Apparel and Fashion companies in New York 334
- IT services companies in New York 331
- Retail chains in New York 326
- Media companies and publishers in New York 304
- Data and analytics companies in New York 303
- Technology, Information and Internet companies in New York 293
The same list elsewhere in United States
- Companies with in-house R&D in the United States 6,796
- Companies with in-house R&D in California 1,276
- Companies with in-house R&D in Texas 442
- Companies with in-house R&D in New York State 419
- Companies with in-house R&D in Massachusetts 396
- Companies with in-house R&D in Illinois 322
- Companies with in-house R&D in Michigan 287
- Companies with in-house R&D in Ohio 277
- Companies with in-house R&D in Pennsylvania 255
- Companies with in-house R&D in New Jersey 224
- Companies with in-house R&D in Florida 221
- Companies with in-house R&D in Alabama 214
- Companies with in-house R&D in Georgia 173
- Companies with in-house R&D in Virginia 166
- Companies with in-house R&D in North Carolina 158
- Companies with in-house R&D in Wisconsin 154
- Companies with in-house R&D in Minnesota 146
- Companies with in-house R&D in Washington State 140
- Companies with in-house R&D in Colorado 113
- Companies with in-house R&D in Maryland 107
- Companies with in-house R&D in Indiana 104
- Companies with in-house R&D in San Francisco 147
- Companies with in-house R&D in Houston 129
- Companies with in-house R&D in San Jose 103