The 100 largest companies in Mississippi (2026 list)

#	Company	Industry	Headquarters	Employees	Founded
1	Mississippi State University msstate.edu Public research university offering diverse academic programs, fostering leadership, and impacting communities locally and globally through education and innovation.	Higher Education	🇺🇸 Mississippi State	8,502	1878
2	University of Mississippi Medical Center umc.edu A leading academic medical center in Mississippi, providing education, research, and high-quality healthcare services to improve health and eliminate disparities	Hospitals and Health Care	🇺🇸 Jackson	6,962	1955
3	University of Mississippi olemiss.edu A public research university in Mississippi with multiple campuses, known for its coeducational programs and medical center in Jackson	Higher Education	🇺🇸 University	6,771	n/a
4	Hancock Whitney hancockwhitney.com An institution with over a century of experience offering a wide range of financial products and services focused on helping clients achieve their goals	Banking	🇺🇸 Gulfport	4,852	1899
5	The University of Southern Mississippi usm.edu A leading research university preparing graduates for success in diverse fields such as polymer science, cybersecurity, education, and sports safety	Higher Education	🇺🇸 Hattiesburg	4,696	1910
6	Cadence Bank cadencebank.com A regional banking franchise offering a full range of banking and financial services, including consumer and business banking, lending, wealth management, and insurance	Banking	🇺🇸 Tupelo	3,431	n/a
7	Ingalls Shipbuilding, a Division of HII hii.com Innovative shipbuilders with 85 years of experience producing advanced naval vessels for various military branches and international clients	Shipbuilding	🇺🇸 Pascagoula	3,360	n/a
8	North Mississippi Health Services nmhs.net Health care system serving 24 counties in north Mississippi and northwest Alabama, offering acute diagnostic and therapeutic services, primary and specialty clinics, managed care plans, and more	Hospitals and Health Care	🇺🇸 Tupelo	3,167	n/a
9	Jackson State University jsums.edu Providing opportunities for success and public service programs in an urban setting, emphasizing quality of life and solutions to urban problems	Higher Education	🇺🇸 Jackson	2,549	1877
10	North Mississippi Medical Center nmhs.net A healthcare organization serving 24 counties in north Mississippi and northwest Alabama, offering diagnostic, therapeutic, and managed care services with a focus on quality and cost-effectiveness	Hospitals and Health Care	🇺🇸 Tupelo	2,316	n/a
11	Trustmark Bank trustmark.com Provides banking and financial solutions across multiple states including Alabama, Florida, Georgia, Mississippi, Tennessee, and Texas.	Banking	🇺🇸 Jackson	2,190	1889
12	Renasant Bank renasantbank.com A financial services institution with $173 billion in assets, operating 195 offices in the Southeast, offering banking, lending, wealth management, and insurance services	Banking	🇺🇸 Tupelo	2,053	1904
13	Yates Construction wgyates.com A leading construction services provider with $2 billion in annual revenues, offering a full range of engineering and construction services globally	Construction	🇺🇸 Philadelphia	2,045	1963
14	Southern Farm Bureau Casualty Insurance Company w3.sfbcic.com A regional property and casualty insurance company offering great rates and friendly service through local agents in multiple states for over 75 years	Insurance	🇺🇸 Ridgeland	1,918	1947
15	Forrest Health forresthealth.org Healthcare organization in south Mississippi with flagship hospital and multiple facilities, focused on quality patient care and creating a compassionate work environment for staff	Hospitals and Health Care	🇺🇸 Hattiesburg	1,905	1952
16	Singing River Health System singingriverhealthsystem.com Comprehensive healthcare provider in South Mississippi with three hospitals, primary care clinics, specialties, and community benefit programs, employing over 3,000 team members	Hospitals and Health Care	🇺🇸 Ocean Springs	1,808	1931
17	BancorpSouth bancorpsouth.com A regional banking division provides relationship-focused financial services, innovative banking solutions, and community support with honesty, integrity, and value	Banking	🇺🇸 Tupelo	1,807	n/a
18	Desoto County Schools desotocountyschools.org This company based in Hernando, Mississippi, specializes in school transportation services	Primary and Secondary Education	🇺🇸 Hernando	1,784	n/a
19	Memorial Hospital at Gulfport wearememorial.com Not-for-profit healthcare system with comprehensive services including trauma care, surgical centers, specialty clinics, and advanced medical technology	Hospitals and Health Care	🇺🇸 Gulfport	1,753	1946
20	C Spire cspire.com A technology provider offering ultra-fast 5G wireless services, high-speed fiber internet, and cutting-edge business solutions to enhance the user experience Apply now	Telecommunications	🇺🇸 Ridgeland	1,671	1988
21	Newk's Eatery newks.com Express casual dining experience emphasizing freshness and flavor with made-from-scratch recipes, premium ingredients, open kitchen, and friendly service across 15 states	Food and Beverage Services	🇺🇸 Jackson	1,666	2004
22	Southern Tire Mart stmtires.com A leading truck retreader and commercial tire dealer in North America, providing high-quality tires and services while prioritizing employee satisfaction and growth opportunities	Motor Vehicle Manufacturing	🇺🇸 Columbia	1,660	1973
23	St. Dominic Hospital stdom.com This company blends high-tech services with high-touch care to provide healing with advanced technology and skilled healthcare professionals while prioritizing patient needs	Hospitals and Health Care	🇺🇸 Jackson	1,608	1946
24	Madison County madison-co.com A fast-growing county in Mississippi with rich history, friendly community, and thriving businesses, attracting settlers for farming in lush, fertile lands	Government Administration	🇺🇸 Canton	1,573	n/a
25	Forrest General Hospital forresthealth.org A leading medical facility in South Mississippi offering a wide range of services including trauma care, behavioral health, rehabilitation, hospice, and long-term acute care	Hospitals and Health Care	🇺🇸 Hattiesburg	1,527	1952
26	Lincoln County School District lcsd.k12.ms.us A dedicated school district in rural communities, serving over 3,000 students from Kindergarten to 12th grade in Brookhaven, Mississippi	Education Administration Programs	🇺🇸 Brookhaven	1,454	n/a
27	Hinds Community College hindscc.edu A leading educational institution in Mississippi, offering affordable and convenient quality educational programs to around 19,500 students annually since 1917	Higher Education	🇺🇸 Raymond	1,306	1917
28	KLLM Transport Services kllm.com A leading temperature-controlled carrier providing long-haul, regional, Mexico, dedicated, intermodal, logistics, and equipment solutions with a focus on safety and customer satisfaction	Truck Transportation	🇺🇸 Richland	1,249	1963
29	Delta State University deltastate.edu A diverse and family-oriented university in the Mississippi Delta offering personalized education and career opportunities for students at all levels	Higher Education	🇺🇸 Cleveland	1,200	n/a
30	Hattiesburg Clinic, PA hattiesburgclinic.com A medical practice that provides high quality, patient-centered healthcare with a focus on commitment, compassion, fairness, integrity, respect, and innovation	Medical Practices	🇺🇸 Hattiesburg	1,196	1963
31	Phi Theta Kappa Honor Society International ptk.org An international honor society for students pursuing associate degrees, providing scholarships, job skills training, and leadership opportunities to members	Higher Education	🇺🇸 Jackson	1,172	1918
32	Hollywood Casino Gulf Coast hollywoodgulfcoast.com A waterfront casino resort offering Las Vegas style gaming, hotel accommodations, dining options, an RV park, and an Arnold Palmer Signature golf course	Gambling Facilities and Casinos	🇺🇸 Bay St Louis	1,152	1992
33	Pascagoula-Gautier School District psd.ms A K-12 public education institution in Gautier and Pascagoula, MS, with 19 campuses serving almost 7,000 students for the past 100 years	Education Administration Programs	🇺🇸 Pascagoula	1,130	1912
34	Catawba Valley Health System catawbavalleyhealth.org Providing high-quality healthcare services and supporting organizations to improve community health in Catawba Valley through compassion and innovation	Hospitals and Health Care	🇺🇸 Hickory	1,115	1968
35	Lamar County School District lamarcountyschools.org This school district provides a quality education in a safe environment, focusing on student success, leadership, and lifelong learning based on core values	Education Administration Programs	🇺🇸 Purvis	1,052	n/a
36	U.S. Army Engineer Research and Development Center (ERDC)erdc.usace.army.mil A research and development center for the US Army Corps of Engineers, specializing in diverse engineering areas and top-ranked facilities worldwide	Research Services	🇺🇸 Vicksburg	1,052	1999
37	Hood Packaging Corporation hoodpkg.com A leading manufacturer of packaging materials with 23 production facilities in the US and Canada, specializing in Paper, Plastic, and Woven packaging substrates	Packaging and Containers Manufacturing	🇺🇸 Madison	1,002	n/a
38	Mississippi Department of Human Services mdhs.ms.gov Providing tangible assistance to people of all ages in Mississippi, instilling lasting hope for the future through their services	Government Administration	🇺🇸 Jackson	988	1935
39	Mississippi College mc.edu A private, Christian university in Mississippi offering liberal arts education, founded in 1826 Affiliated with the Mississippi Baptist Convention	Higher Education	🇺🇸 Clinton	986	1826
40	Southern Farm Bureau Life Insurance Company sfbli.com An insurance company that prioritizes people by providing competitive products, superior customer service, and fostering employee development and engagement	Insurance	🇺🇸 Jackson	964	1946
41	Ergon Inc.ergon.com A well-established, family-owned organization in the petroleum industry providing reliable supply, quality products, and exceptional customer service worldwide for over 60 years	Oil and Gas	🇺🇸 Flowood	950	1954
42	Cal-Maine Foods, Inc.calmainefoods.com A leading producer and distributor of shell eggs in the US, focused on sustainability, quality, and value for shareholders, customers, and communities	Food and Beverage Manufacturing	🇺🇸 Ridgeland	913	n/a
43	Meridian Community College meridiancc.edu A public institution offering diverse programs for higher education, workforce training, continuing education, and support services to enhance employment opportunities and personal enrichment	Higher Education	🇺🇸 Meridian	888	1937
44	Rankin County School District rcsd.ms A large school district in Mississippi serving nearly 19,500 students across 28 schools in a 757 square mile area with the lowest tax rate in the metro Jackson area	Education Administration Programs	🇺🇸 Brandon	835	1900
45	SchoolStatus schoolstatus.com The company empowers schools with data-driven tools to enhance communication and engagement for student success among families, educators, and administrators	Education Administration Programs	🇺🇸 Ridgeland	814	2012
46	YoungWilliams youngwilliams.com YoungWilliams supports government agencies in providing streamlined, efficient services to individuals and families, offering customer service, payment processing, and operational solutions	Government Administration	🇺🇸 Ridgeland	762	1994
47	Belhaven University belhaven.edu Christian liberal arts college focusing on leadership preparation, individual growth, and integrating academic learning with Christian values and community.	Higher Education	🇺🇸 Jackson	760	1883
48	Butler Snow LLP butlersnow.com A team of over 400 attorneys offering business law and litigation services nationally and internationally, focusing on client satisfaction and innovative solutions	Legal Services	🇺🇸 Ridgeland	751	1954
49	The Vertex Company gov2x.com Global aerospace company providing rotary and fixed-wing aircraft maintenance and logistical solutions for government and private sector customers Strong military support and high veteran employee rate	Defense and Space Manufacturing	🇺🇸 Madison	734	1975
50	William Carey University wmcarey.edu A community of learners blending faith and learning, offering a wide range of undergraduate, graduate, and doctoral degrees in various fields	Higher Education	🇺🇸 Hattiesburg	708	1892
51	Irby Construction Company irbyconstruction.com Specializes in major transmission, substation, and distribution line construction across the U.S. and Canada with extensive electric construction experience.	Construction	🇺🇸 Richland	697	n/a
52	Howard Technology Solutions howardcomputers.com Provider of cutting-edge technology solutions, offering high quality and affordable products including desktops, notebooks, servers, and medical carts from Howard-manufactured and leading partner brands	Technology, Information and Internet	🇺🇸 Ellisville	696	1998
53	South Central Regional Medical Center scrmc.com A not-for-profit hospital in Laurel, MS providing excellent healthcare services to residents in South Central Mississippi with 80 physicians and over 2,100 employees	Hospitals and Health Care	🇺🇸 Laurel	692	1952
54	Tower Loan towerloan.com Established in 1936, the company started as a single office and grew to multiple locations, offering consumer finance services and expanding operations into multiple states	Financial Services	🇺🇸 Flowood	687	1936
55	Mississippi State Hospital msh.ms.gov A publicly funded psychiatric treatment facility in Mississippi, offering various services including acute and continued treatment, forensic, and substance use services	Hospitals and Health Care	🇺🇸 Whitfield	681	1855
56	Mcallisters Deli Hospitality services provider with a location in Jackson, Mississippi, focusing on food and dining experiences for customers	Hospitality	🇺🇸 Jackson	672	n/a
57	Total Transportation of MS totalms.com A dedicated team providing efficient and safe transportation services across the US, committed to customer satisfaction, safety, and reliability	Truck Transportation	🇺🇸 Richland	667	1990
58	IACO Agricola S/A ind.br This company transforms natural resources into competitive agro-industrial products and services, prioritizing customer satisfaction, technology, and environmental respect Join us!	Renewable Energy Power Generation	🇺🇸 Chapadao Do Sul	661	n/a
59	Mississippi Department of Corrections mdoc.ms.gov A law enforcement agency that focuses on corrections and maintaining public safety within the community	Law Enforcement	🇺🇸 Jackson	656	n/a
60	Keesler Federal Credit Union kfcu.org A dynamic, financially strong credit union serving over 300,000 members with $4 billion in assets across Mississippi Gulf Coast, Mobile, New Orleans, and more	Financial Services	🇺🇸 Biloxi	656	1947
61	Jones College jcjc.edu A publicly supported two-year college in south Mississippi offering academic, technical, and vocational courses leading to degrees and certificates Committed to quality education	Higher Education	🇺🇸 Ellisville	655	1911
62	Merit Health mymerithealth.com A healthcare organization that operates hospitals and provides medical care services	Hospitals and Health Care	🇺🇸 Flowood	655	n/a
63	Neel-Schaffer, Inc.neel-schaffer.com Multi-disciplined engineering and planning firm offering transportation, civil site, environmental, water/wastewater services across the South with a focus on community improvement	Civil Engineering	🇺🇸 Jackson	647	1983
64	Mississippi Department of Child Protection Services mdcps.ms.gov State agency in Mississippi focused on protecting children, supporting families, and preventing child abuse and neglect through various programs and services	Government Administration	🇺🇸 Jackson	635	n/a
65	Vicksburg Warren School District vwsd.org A public education entity in Mississippi serving the Vicksburg, Warren County area, focused on teaching and inspiring students to achieve their aspirations	Education Administration Programs	🇺🇸 Vicksburg	633	1988
66	Magnolia Regional Health Center mrhc.org A 200-bed acute care community hospital in Mississippi, jointly owned by the City of Corinth and Alcorn County, offering various medical services and employing over 1,500 people	Hospitals and Health Care	🇺🇸 Corinth	626	1965
67	Pearl River Community College prcc.edu Offering academic, vocational, and continuing education programs with on-campus housing, dual enrollment, and online courses for a strong academic foundation	Higher Education	🇺🇸 Poplarville	624	1909
68	Mississippi Gulf Coast Community College mgccc.edu The company provides superior instruction through traditional and technological formats to offer various educational pathways in Mississippi Gulf Coast	Higher Education	🇺🇸 Perkinston	610	1911
69	Mississippi Baptist Health Systems baptistonline.org A Christian healing ministry focused on providing quality care, recognized for excellence, with employees committed to high standards of performance	Hospitals and Health Care	🇺🇸 Jackson	601	1908
70	Mississippi Power mississippipower.com A company providing safe, reliable, and affordable energy to over 191,000 customers in southeast Mississippi, along with community wellness support	Utilities	🇺🇸 Gulfport	601	1925
71	Gulfport School District gulfportschools.org A public school district that serves students from pre-kindergarten to grade 12	Education Administration Programs	🇺🇸 Gulfport	594	n/a
72	Irby Co.irby.com A distributor of electrical supplies and services catering to industrial, commercial, contractor, and utility businesses representing major electrical manufacturing lines	Wholesale	🇺🇸 Jackson	585	1926
73	Mississippi Valley State University mvsu.edu A Carnegie Classified Master's University offering comprehensive undergraduate and graduate programs in education, arts, sciences, and professional studies Committed to excellence in teaching and research	Higher Education	🇺🇸 Itta Bena	576	1950
74	Venture Technologies West convergeone.com Premier IT solutions provider offering infrastructure, collaboration, cloud services, and business applications consulting to organizations in the US and abroad	IT Services and IT Consulting	🇺🇸 Ridgeland	565	1998
75	Ochsner Rush Health ochsnerrush.org A non-profit healthcare system serving east Mississippi and west Alabama, dedicated to healing, leading, educating, and innovating in local communities	Hospitals and Health Care	🇺🇸 Meridian	562	1915
76	Convience Store Consumer goods company located in Magee, Mississippi that operates a convenience store providing a variety of products for daily needs	Manufacturing	🇺🇸 Magee	561	n/a
77	District Health Office Facilities services company located in Hattiesburg, Mississippi, providing services related to district health office operations	Facilities Services	🇺🇸 Hattiesburg	550	n/a
78	Northwest Mississippi Community College northwestms.edu An open-access, public, two-year institution providing quality education in academic, health sciences, and career-technical fields for students in multiple counties	Higher Education	🇺🇸 Senatobia	544	1927
79	Community Bank communitybank.net A fast-growing financial institution with a unique approach, originally from a small community, now with over $42 billion in assets	Banking	🇺🇸 Brandon	533	1904
80	Oxford School District oxfordsd.org A top-ranked K-12 school district in Oxford, Mississippi, providing rigorous academics, extracurricular activities, and student support for well-rounded education and growth	Primary and Secondary Education	🇺🇸 Oxford	528	n/a
81	Hard Rock Hotel & Casino Biloxi hrhcbiloxi.com A casino hotel in Biloxi, offering a wide range of gaming options, dining choices, live entertainment, and career opportunities	Hospitality	🇺🇸 Biloxi	522	2007
82	Wise Staffing Group wisestaffinggroup.com A full-service human resource company specializing in temporary and career staffing, focused on providing excellent customer service in the Southeast	Staffing and Recruiting	🇺🇸 Tupelo	501	1987
83	Channel Control Merchants, LLC ccmllc.com Extreme value retailer and exporter managing brand-sensitive secondary market inventories through physical stores and wholesale channels across multiple regions.	Transportation, Logistics, Supply Chain and Storage	🇺🇸 Hattiesburg	500	n/a
84	Itawamba Community College iccms.edu The company recently unveiled its new brand, symbolizing its identity after months of planning, discussions, and work Excited to share!	Higher Education	🇺🇸 Fulton	495	n/a
85	Sprint Mart sprintmart.com A company focused on providing excellent service, coffee, and convenience to customers, aiming to ensure each guest has a great day	Retail	🇺🇸 Ridgeland	460	1992
86	Mississippi University for Women muw.edu A public, coeducational university with a rich tradition of educating both men and women, consistently ranked among the top in the nation	Higher Education	🇺🇸 Columbus	455	1884
87	Blossman Gas blossmangas.com Established in 1951, this family-owned propane business offers tailored solutions, competitive pricing, and reliable service with a focus on customer satisfaction	Oil and Gas	🇺🇸 Ocean Springs	450	1951
88	Mississippi Department of Education mdek12.org The Mississippi Department of Education supports public schools by implementing education laws, disbursing funds, holding schools accountable, and ensuring student success in college and career	Education	🇺🇸 Jackson	446	n/a
89	Holmes Community College holmescc.edu A public institution in Central Mississippi offering innovative and affordable higher education through campus-based and distance learning programs	Higher Education	🇺🇸 Goodman	443	1911
90	Millsaps College millsaps.edu A nationally recognized liberal arts college in Mississippi, offering high value higher education with praise from various reputable sources	Higher Education	🇺🇸 Jackson	443	1890
91	Southern Pipe & Supply Co.southernpipe.com Independent wholesale distributor providing brand name plumbing, heating, air-conditioning, industrial, mechanical, and waterworks supplies through over one hundred locations across the Southeast.	Wholesale	🇺🇸 Meridian	443	1938
92	JHU APL jhuapl.edu The Johns Hopkins Applied Physics Lab conducts research and development in collaboration with government agencies, focusing on national security and space exploration	Defense and Space Manufacturing	🇺🇸 Laurel	442	1942
93	Greenwood Leflore Hospital glh.org A 208-bed healthcare organization offering advanced medical and surgical care, serving as a regional hub for North Central Mississippi for over 100 years	Hospitals and Health Care	🇺🇸 Greenwood	435	n/a
94	CoreLogic \| FNC fncinc.com A team of skilled professionals revolutionizing the global real estate economy with simple software solutions for mortgage, appraisal, and insurance industries	Software Development	🇺🇸 Oxford	424	1995
95	Hancock Fabrics hancockfabrics.com A company founded in 1957, specializing in fabric, sewing, crafts, and home decorating supplies, with retail stores in 37 states and an online store	Retail	🇺🇸 Baldwyn	423	1957
96	Treasure Bay Casino and Hotel treasurebay.com A beachside casino resort in Biloxi, Mississippi offering gaming, dining, and accommodation with a sophisticated redesign after Hurricane Katrina	Gambling Facilities and Casinos	🇺🇸 Biloxi	417	1994
97	Irby Utilities irby.com Leading provider of products, services, and solutions to utility and utility contracting industries Specializing in distribution, transmission, substation, renewable energy, and more	Utilities	🇺🇸 Jackson	411	1926
98	Hood Industries, Inc.hoodindustries.com A blend of wood manufacturing and distribution, with a focus on safety, customer satisfaction, sustainable growth, serving multiple regions in the US	Paper and Forest Product Manufacturing	🇺🇸 Hattiesburg	410	1986
99	CLUB4 Fitness club4fitness.com Membership-based health facility with extensive equipment, workout classes, amenities, and exceptional service to help members reach their fitness goals	Wellness and Fitness Services	🇺🇸 Madison	409	2002
100	Naval Oceanographic Office Providing oceanographic products and services for military and civilian customers worldwide, maximizing maritime environmental knowledge for warfighter maneuverability and lethality	Armed Forces	🇺🇸 Stennis Space Center	402	1830

Turn this list into pipeline

Tamtam finds the decision-makers at every company on a list like this one, with verified emails, phone numbers and the buying signals that tell you when to reach out.

Build your own list, free

How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Oct 24, 2026.

More company lists in Mississippi

The same list elsewhere in United States

The largest companies in the United States 91,669
The largest companies in California 12,813
The largest companies in New York State 10,485
The largest companies in Texas 8,086
The largest companies in Florida 4,945
The largest companies in Illinois 4,175
The largest companies in Pennsylvania 3,110
The largest companies in Massachusetts 3,093
The largest companies in Georgia 2,632
The largest companies in Ohio 2,618
The largest companies in New Jersey 2,569
The largest companies in Virginia 2,503
The largest companies in Michigan 2,346
The largest companies in North Carolina 2,174
The largest companies in Alabama 1,806
The largest companies in Washington State 1,785
The largest companies in Colorado 1,774
The largest companies in Minnesota 1,700
The largest companies in Maryland 1,527
The largest companies in Wisconsin 1,482
The largest companies in New York 6,920
The largest companies in San Francisco 2,030
The largest companies in Houston 1,791
The largest companies in Chicago 1,668