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Top 50 medical device companies in Spain

Tamtam tracks 72 medical device companies headquartered in Spain. This list ranks the 50 largest by number of employees on LinkedIn, led by Grifols, Werfen and Exeltis. Their median headcount is 194. Half of them were founded in 1995 or later. The most common headquarters are Madrid (6), Barcelona (4) and Sant Cugat del Vallès (3).

🇪🇸 Spain50 companiesUpdated Nov 12, 2026

These companies are primarily large and mid-sized firms in Spain's medical device and pharmaceutical sectors. They specialize in a range of healthcare solutions, from plasma-derived medicines to diagnostic systems. Grifols is a global healthcare company focusing on plasma-derived medicines, while Werfen specializes in diagnostic solutions. HIPRA develops vaccines for animal and human health, and Impress provides clear aligner orthodontic treatments.

A notable pattern among these companies is the concentration of headquarters in Catalonia, particularly around Barcelona, with several firms also based in Madrid. The firms represent a mix of established players, such as Grifols (founded 1909) and Prim (a Spanish private capital group), alongside more recent ventures like Impress (founded 2019) in orthodontics.

#CompanyIndustryHeadquarters EmployeesFounded
1
Grifolslinktr.ee

A global healthcare company specializing in plasma-derived medicines, transfusion medicine, and innovative healthcare solutions, committed to improving people's health worldwide

Pharmaceutical Manufacturing 🇪🇸 Sant Cugat del Vallès 14,329 1909
2
Werfenwerfen.com

A global innovator in specialized diagnostics, offering Hemostasis, Acute Care Diagnostics, Transfusion, Autoimmunity, and Transplant solutions through OEM manufacturing and distribution

Medical Equipment Manufacturing 🇪🇸 L'Hospitalet de Llobregat 6,858 n/a
3
Exeltisexeltis.com

Innovative global organization in the pharmaceutical sector, committed to improving health through the development and marketing of medicinal products worldwide

Pharmaceutical Manufacturing 🇪🇸 Madrid 2,659 2003
4
HIPRAhipra.com

Biotechnological pharmaceutical company specializing in innovative vaccines and diagnostic services for animal and human health worldwide

Pharmaceutical Manufacturing 🇪🇸 Amer 2,113 n/a
5
Impresssmile2impress.com

Providing personalized clear aligner orthodontic treatments across Europe and the US, focusing on comfort, discretion, and visible results quickly.

Hospitals and Health Care 🇪🇸 Barcelona 1,002 2019
6
Prim, S.A.prim.es

A Spanish private capital group in the healthcare sector, providing advanced products and solutions to hospitals, clinics, health centers, and individuals

Wellness and Fitness Services 🇪🇸 Móstoles 711 n/a
7
Promedonpromedon.com

International leader in medical technology research, development, production, and distribution Specializes in Urology, Urogynecology, Sports Medicine, Arthroscopy, and various surgical solutions in multiple countries

Medical Equipment Manufacturing 🇪🇸 Córdoba 685 1985
8
BioSystemsbiosystems.global

Global group specializing in In-vitro human and veterinary clinical diagnostics, food & beverage analysis, and bioprocess monitoring, with a focus on user experience and innovation

Biotechnology Research 🇪🇸 Barcelona 643 1981
9
Hologic (Formerly Gen-Probe)hologic.com

Develops, markets, and services innovative diagnostic imaging systems and surgical products globally, providing greater confidence in diagnoses and enabling healthier lives for people everywhere.

Biotechnology Research 🇪🇸 520 1986
10
Roche Diagnostics Españaroche.es

A global company pioneering research in diagnostic solutions to advance science, improve lives, and lead personalized medicine with integrated healthcare solutions

Biotechnology Research 🇪🇸 Sant Cugat del Vallès 482 1896
11
SEDECALsedecal.com

Global leader in OEM design and manufacturing of high frequency X-Ray generators and systems, with divisions in medical, veterinary, healthcare, and industrial sectors

Medical Equipment Manufacturing 🇪🇸 Algete 476 1994
12
Idneoidneo.com

Engineering service company specializing in design, development, certification, and manufacturing of high-value products across various markets globally.

Appliances, Electrical, and Electronics Manufacturing 🇪🇸 Mollet del Vallès 450 2011
13
MATACHANAmatachana.com

A global provider of technological solutions for Healthcare and Life Science sectors, specializing in sterilization, washing, and surgical units With a strong focus on research and development

Machinery Manufacturing 🇪🇸 Castelldefels 433 1962
14
mesoestetic Pharma Groupmesoestetic.es

A leading pharmaceutical laboratory specializing in dermatology and aesthetic medicine, offering innovative solutions for skin treatment, including cosmeceuticals and medical devices

Pharmaceutical Manufacturing 🇪🇸 Viladecans 424 1985
15
Inibsainibsa.com

A Barcelona-based pharmaceutical company with 75 years of experience, specializing in dental products and services sold in over 60 countries

Pharmaceutical Manufacturing 🇪🇸 Lliçà de Vall 411 1948
16
Inmunotekinmunotek.com

A pharma company developing therapeutic vaccines for allergy, infectious diseases, and cancer, as well as medical devices, sold globally Founded in 1992 for patient and healthcare professional benefit

Pharmaceutical Manufacturing 🇪🇸 Alcalá de Henares 382 1992
17
Werfen Immunoassaywerfen.com

Specializes in research, development, and manufacturing of customized assays and biomaterials for the IVD industry, enhancing competitiveness and time-to-market

Biotechnology Research 🇪🇸 Lliçà d'Amunt 327 1973
18
Coruscorusdental.com

A network of dental laboratories in Europe offering innovative products and services for modern dentistry, focusing on quality patient care

Medical Equipment Manufacturing 🇪🇸 Sant Cugat del Vallès 323 2015
19
Telstartelstar.com

Engineering, construction, and integrated process equipment provider specializing in GMP consultancy and aseptic solutions for life sciences, pharmaceutical, biotechnology, and healthcare industries worldwide.

Machinery Manufacturing 🇪🇸 Terrassa 321 1963
20
MBA SURGICAL EMPOWERMENTmba.eu

A leading European medical and surgical technology provider offering a wide range of solutions for orthopaedic, neurosurgery, anesthesiology, and other surgical specialties

Medical Equipment Manufacturing 🇪🇸 Gijón 309 1988
21
AMES - Sintered metallic componentsames.group

A manufacturing company founded in 1951, specializing in sintered metal components such as structural parts, bearings, filters, membranes, and biomedical implants

Industrial Machinery Manufacturing 🇪🇸 St. Feliu de Llobregat 303 1951
22
BTI Biotechnology Institutebti-biotechnologyinstitute.com

A Spanish multinational specializing in regenerative medicine and oral implantology, focused on research, development, and training in biomedicine

Biotechnology Research 🇪🇸 Vitoria-Gasteiz 246 1995
23
Laboratorios Rubiólaboratoriosrubio.com

Pharmaceutical company dedicated to providing medications for low-prevalence diseases, ADHD treatment, clinical nutrition, and diagnostics with a focus on accessibility and quality of life

Pharmaceutical Manufacturing 🇪🇸 Castellbisbal 243 1968
24
Certest Biotec, S.L.certest.es

Specialized company with four divisions providing raw materials, immunodiagnostics, molecular biology solutions, and pharma technology for IVD assays and therapeutic products

Biotechnology Research 🇪🇸 San Mateo de Gállego 203 2002
25
Fresenius Kabi Españafresenius-kabi.com

Healthcare company providing solutions for healthcare professionals through a wide range of medicines, infusion technologies, clinical nutrition, and medical devices Operating globally with a mission of Advancing Patient Care

Pharmaceutical Manufacturing 🇪🇸 Barcelona 194 n/a

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26
Quibimquibim.com

Quibim specializes in developing innovative tools that utilize AI to analyze medical imaging data, enabling better patient outcomes and actionable predictions for healthcare

Biotechnology Research 🇪🇸 Valencia 120 2015
27
IPD Dental Group Iberiaipd2004.com

A global leader in designing, manufacturing, and distributing dental implant abutments, providing innovative prosthetic solutions with high-quality products and cutting-edge technology

Medical Equipment Manufacturing 🇪🇸 Premià de Dalt 114 2004
28
DVD Dental Solutionsdvd-dental.com

A leading dental company providing innovative solutions and value for dental professionals, offering a wide range of products and services

Medical Equipment Manufacturing 🇪🇸 Sant Boi de Llobregat 102 1988
29
Neftis Laboratoriosneftislaboratorios.com

A Contract Manufacturer specializing in professional cosmetics, Medical Devices, and bespoke formulations, offering technical support and compliance with regulations

Personal Care Product Manufacturing 🇪🇸 Santa Eulàlia de Ronçana 86 2005
30
Idovenidoven.ai

Health technology company utilizing AI for early detection of cardiovascular diseases through ECG interpretation and disease biomarker development for precision medicine

Software Development 🇪🇸 Madrid 70 2018
31
Ortopronoortoprono.es

Ortoprono specializes in technical orthopedics, providing quality products and services for adults and children, collaborating closely with healthcare professionals for innovative solutions

Wellness and Fitness Services 🇪🇸 Valencia 69 1969
32
SecretAlignersecretaligner.com

Specializing in invisible orthodontics, all cases designed by orthodontists in Spain Continual training and excellence standards upheld

Wellness and Fitness Services 🇪🇸 Madrid 58 2017
33
Prótesis S.A.protesis.com

The company specializes in all types of dental prosthetics, offering precision implant work, fixed prosthetics with various materials, cosmetic options, and removable prosthetics since 1953

Wellness and Fitness Services 🇪🇸 Madrid 55 n/a
34
Eckermanneckermann.es

A Spanish company specializing in advanced implantology services, with expertise in manufacturing and a dedicated customer service approach

Wellness and Fitness Services 🇪🇸 Almoradí 55 1998
35
NESA WORLDnesa.world

NESA WORLD® is a medical technology company specializing in non-invasive autonomic nervous system rehabilitation, offering innovative microcurrent system for chronic pain relief and stress reduction

Wellness and Fitness Services 🇪🇸 San Sebastián 53 n/a
36
Rob Surgicalrobsurgical.com

Develops a flexible four-arm robotic platform for hybrid surgeries, combining manual and high-precision robot-assisted maneuvers to improve safety and reduce operation costs.

Medical Equipment Manufacturing 🇪🇸 El Prat de Llobregat 47 2012
37
IRE RAYOS X, S.A.irerayosx.com

The company specializes in X-ray equipment and software development for radiology services, offering radiology machinery and digital hospital systems compliant with industry standards

Wellness and Fitness Services 🇪🇸 San Sebastián de los Reyes 45 1997
38
RÖS'S - Ross estéticaross.international

Manufacturer of advanced technology for aesthetics, physiotherapy, medical aesthetics, and wellness, including tecartherapy, radiofrequency, electrostimulation, and physioactive massage equipment Designed and made in Spain since 1978

Wellness and Fitness Services 🇪🇸 Castelldefels 44 1978
39
Ambu - Españaambu.es

Since 1937, this company has been revolutionizing medical solutions to save lives and improve patient care worldwide through innovative patient monitoring, anesthesia, and endoscopy solutions

Medical Equipment Manufacturing 🇪🇸 Madrid 41 1937
40
IT Pharmaitpharma.com

A Spanish company in Pamplona specializing in mesotherapy and aesthetic medicine, with over 30 years of experience in developing sterile, personalized products

Personal Care Product Manufacturing 🇪🇸 Huarte 41 2005
41
FLEXOR S.A.flexor.es

Specializing in latex insoles for healthy and comfortable walking, we aim to improve foot health and comfort since 1963

Wellness and Fitness Services 🇪🇸 Barberà del Vallès 38 1963
42
EMO - especialistas en ortopediaemo.es

A global leader in orthopedic specialties manufacturing and distribution serving clients in over 30 countries across all continents since 1970

Wellness and Fitness Services 🇪🇸 Paiporta 37 1970
43
Corus OrthoLabclubortholab.es

A company specializing in supplying dental clinics with products, laboratory services, and training for various specialties in the dental field

Wellness and Fitness Services 🇪🇸 Elda 35 2005
44
DyCare - Digital Rehabilitationdycare.com

The company provides innovative digital solutions in the rehabilitation sector, improving diagnosis quality, monitoring recovery, and personalizing patient follow-up for professionals and healthcare institutions

Wellness and Fitness Services 🇪🇸 Barcelona 31 2015
45
Bader Dentalbader.es

A Spanish company specializing in manufacturing, importing, and exporting dental instruments They offer a personalized approach and full solutions to dental distributors

Medical Equipment Manufacturing 🇪🇸 Nigrán 27 2007
46
Medicsenmedicsen.com

A Spanish startup developing a revolutionary diabetes treatment with an app for glucose monitoring and insulin delivery patch, seeking patient support and collaboration opportunities

Medical Equipment Manufacturing 🇪🇸 Madrid 24 2015
47
Aragoneses CPD Dental Labaragonesescpd.com

Aragoneses CPD is a dental laboratory with over 70 years of experience, creating personalized prostheses using the latest technology and traditional techniques for clients in Spain and Europe

Wellness and Fitness Services 🇪🇸 Alcobendas 24 1950
48
KMINAkmina.com

A European company specializing in developing and distributing orthopedic and health solutions to improve mobility and daily life for clients globally

Wellness and Fitness Services 🇪🇸 Valencia 23 2016
49
SINELDENT®sineldent.com

Specialized in CAD/CAM dental prosthesis manufacturing using additive technology, contributing to dental lab modernization and digital workflow development within the market segments

Wellness and Fitness Services 🇪🇸 Ourense 23 2008
50
OrthoApneaorthoapnea.com

OrthoApnea provides high-quality Sleep Apnea Oral Appliances to improve patients' health, well-being, and happiness through compassionate care and advanced techniques

Wellness and Fitness Services 🇪🇸 Málaga 23 2009

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How this list is built

Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 12, 2026.

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