This list covers major companies with in-house R&D operations in Spain. It includes large, established firms such as Santander, a global bank, Telefónica, a telecommunications leader, and Inditex, a global clothing and home goods conglomerate. Other notable companies are Quirónsalud, a healthcare provider, and Iberdrola, specializing in renewable energy.
Many of the companies featured are headquartered in Madrid, indicating a concentration of large corporate R&D activity in the capital. The sectors represented are diverse, ranging from banking and telecommunications to retail, healthcare, and energy.
| # | Company | Employees | |||
|---|---|---|---|---|---|
| 1 |
MITSUBISHI ELECTRICmitsubishielectric.com
A leader in electric and electronic equipment manufacturing, focusing on Energy Systems, Industrial Automation, Information Systems, Electronic Devices, and Home Appliances |
146,000 | |||
| 2 |
Santandersantander.com
Leading global bank offering retail, corporate, investment banking, wealth management, insurance, and payment services to diverse clients worldwide. |
129,701 | |||
| 3 |
Telefónicatelefonica.com
Leading global telecommunications company providing advanced infrastructure, innovative digital and data services, focusing on secure, cutting-edge technology and social impact. |
121,569 | |||
| 4 |
Inditexinditexpeople.com
A global conglomerate of clothing brands and home goods, with online and physical presence in 213 markets, led by a dedicated team focused on continuous improvement |
73,716 | |||
| 5 |
Quirónsaludquironsalud.com
Leader in healthcare in Spain and Europe with over 50,000 professionals and 59 hospitals, focusing on medical research, education, and cutting-edge technology |
50,000 | |||
| 6 |
Iberdrolaiberdrola.com
A global leader in renewable energy and electricity, focusing on sustainable and efficient services for millions worldwide with investments in clean energy and digital transformation |
45,000 | |||
| 7 |
Indra Groupindragroup.com
Leading multinational providing defense, space, air traffic management, and mobility solutions alongside information technology services, artificial intelligence, cybersecurity, and advanced digital transformation projects. |
39,308 | |||
| 8 |
ACCIONAacciona.com
The company specializes in developing regenerative infrastructure with a focus on sustainability, leading the transition to a low-carbon economy with a positive impact on people and the planet |
33,828 | |||
| 9 |
NTT DATA Europe & Latamnttdata.com
Global IT services provider transforming clients through consulting, solutions, and managed services to enable a confident move into the digital future |
31,932 | |||
| 10 |
repsolrepsol.com
A leading player in the oil and gas industry, involved in exploration, production, transformation, development, and marketing of efficient, sustainable energy solutions globally |
26,030 | |||
| 11 |
Amadeusamadeus.com
A company revolutionizing the travel industry by inspiring innovation, partnerships, and responsibility, connecting the travel ecosystem and promoting social and environmental good |
23,625 | |||
| 12 |
Applus+applus.com
A global leader in testing, inspection, and certification services, providing innovative solutions for asset integrity, regulatory compliance, and environmental performance |
20,046 | |||
| 13 |
Siemens Gamesasiemensgamesa.com
Global technology leader in renewable energy industry, specializing in wind turbine development, manufacturing, installation, and maintenance Driving energy transition towards sustainability |
19,821 | |||
| 14 |
Gestampgestamp.com
A multinational company specializing in designing and manufacturing advanced metal components for vehicle manufacturers worldwide, focusing on lighter, safer, and more environmentally friendly products |
17,667 | |||
| 15 | 14,329 | ||||
| 16 |
Universidad Complutense de Madriducm.es
A public university in Madrid offering high-quality education, research opportunities, international collaborations, extensive library resources, diverse cultural activities, and sports facilities |
14,024 | |||
| 17 |
EVOLUTION MADRID SL.evolution.com
A world-leader in innovative IT solutions for live casino streaming, processing millions of transactions globally with a market cap of over EUR 20B |
14,000 | |||
| 18 |
Universidad Autónoma de Madriduam.es
Institution recognized for high-quality research, entrepreneurial capacity, teaching excellence, and social commitment. Actively promotes international exchange and training programs. |
14,000 | |||
| 19 |
Tecnicas Reunidastecnicasreunidas.es
An international general contractor specializing in engineering and construction of industrial facilities in oil & gas, refining, power generation, infrastructures, and energy transition |
12,368 | |||
| 20 |
Grupo Tragsatragsa.es
Provides engineering, technical assistance, and execution of projects for public administrations in agriculture, environment, and rural development sectors. |
12,239 | |||
| 21 | 11,873 | ||||
| 22 |
Elecnor Groupgrupoelecnor.com
Global corporation specializing in engineering, construction, sustainable projects, infrastructure investments, renewable energy, asset management, and energy transmission across 50 countries. |
10,383 | |||
| 23 |
Universitat de Barcelonaweb.ub.edu
Leading Spanish university with extensive research departments, numerous projects, and collaborations with national and European institutions and businesses. |
10,368 | |||
| 24 |
CAF (Construcciones y Auxiliar de Ferrocarriles)cafmobility.com
Designs and manufactures advanced sustainable transportation systems including accessible rail vehicles and zero-emission urban buses worldwide. |
10,000 | |||
| 25 |
Universitat Autònoma de Barcelonauab.cat
The organization is a pioneering, research-focused university in Barcelona, known for its diversity, sustainability, and campus culture, offering unique experiences |
8,649 | |||
| 26 | 8,620 | ||||
| 27 | 8,030 | ||||
| 28 |
Antolinantolin.com
Design, development, and manufacture of modular automotive interior components including overhead, door, lighting, cockpits, and electronic systems worldwide. |
7,947 | |||
| 29 |
Institut Català de la Salutics.gencat.cat
The company provides healthcare services from pregnancy to old age, with a wide territorial coverage and a strong emphasis on education, research, and innovation |
7,936 | |||
| 30 |
Roca Grouprocagroup.com
Global enterprise manufacturing and selling bathroom solutions across 170 countries with 81 production plants to improve quality of life through sustainable development. |
7,451 | |||
| 31 |
Universidad de Granadaugr.es
The company is a university known for high-quality research, with 346 research groups, 165 projects, and partnerships with businesses and international organizations |
7,376 | |||
| 32 |
Eroskicorporativo.eroski.es
A multinational socio-business group with over 50,000 employees, specializing in retail sales through a vast network of supermarkets and hypermarkets |
7,340 | |||
| 33 |
Insud Pharmainsudpharma.com
Specialized pharmaceutical company with global presence, offering APIs, finished dosage forms, branded medicines, and biotech solutions for human and animal health. |
7,035 | |||
| 34 |
Werfenwerfen.com
A global innovator in specialized diagnostics, offering Hemostasis, Acute Care Diagnostics, Transfusion, Autoimmunity, and Transplant solutions through OEM manufacturing and distribution |
6,858 | |||
| 35 | 6,560 | ||||
| 36 |
Universidad Politécnica de Madridupm.es
Educates students in architecture, engineering, sport, and fashion design, conducts research, and secures significant R&D funding from European and national programs. |
6,447 | |||
| 37 |
Hospital Clínic de Barcelonaclinicbarcelona.org
A leading public university hospital in Spain, offering quality healthcare, cutting-edge research, and professional training with a focus on humanized medicine |
6,159 | |||
| 38 | 5,743 | ||||
| 39 |
IDOM Consulting, Engineering, Architectureidom.com
A multinational consulting, engineering, and architecture firm offering personalized client services, delivering independent, impartial global projects with a diverse, engaged workforce |
5,424 | |||
| 40 | 5,416 | ||||
| 41 |
Universitat Politècnica de Catalunyaupc.edu
Public institution specializing in engineering, architecture, science, technology education and research, promoting innovation, sustainability, and social responsibility. |
5,306 | |||
| 42 |
Universidad de Zaragozaunizar.es
A prestigious center of technological innovation in the Ebro Valley with strong relationships with Spanish and European universities, tracing its origins back to Ecclesiastical Schools |
5,038 | |||
| 43 |
Universidad Rey Juan Carlosurjc.es
Public university offering diverse degree programs, including English and blended learning, promoting cooperation with institutions for academic excellence. |
4,984 | |||
| 44 |
Senergroup.sener
Responds to demanding challenges with innovative, efficient solutions, advancing society across aerospace, defense, energy, mobility, data centers, and digital sectors for 70 years. |
4,878 | |||
| 45 |
Management Solutionsmanagementsolutions.com
Providing consulting services in strategy, organization, risk management, and technology for financial, energy, and telecommunications sectors worldwide. |
4,798 | |||
| 46 | 4,520 | ||||
| 47 |
Universidad de Salamancausal.es
A prestigious university founded in 1218, offering a wide range of undergraduate, master's, doctoral, and continuing education programs to over 30,000 students |
4,385 | |||
| 48 |
Hospital Universitari Vall d'Hebronvallhebron.com
A leading hospital complex in Catalonia with four large centers offering a wide range of medical and surgical specialties |
4,361 | |||
| 49 |
OHLA Groupohla-group.com
A global leader in construction, engineering, and development projects, focusing on transport infrastructure, unique buildings, and sustainable progress in various regions worldwide |
4,270 | |||
| 50 | 4,163 | ||||
Want more companies than this list?This page shows the largest ones only. Connect to Tamtam to see every company that matches, filter by size, industry or growth, and reach their decision-makers. | |||||
| 51 |
GRI RENEWABLE INDUSTRIES SLgri.com.es
Manufactures towers and flanges for the wind energy sector globally, including onshore and offshore towers, wind flanges, and wind castings components. |
4,000 | |||
| 52 |
Universidade do Minhouminho.pt
Higher education institution in Portugal focusing on quality education, cutting-edge research, sustainability, and international recognition in a dynamic environment. |
3,939 | |||
| 53 |
SEMsemgrupo.es
Specializing in surface treatment, we are pioneers in metal coatings for various sectors including equipment, aerospace, energy generation, and oil & gas industries |
3,931 | |||
| 54 |
Universidad de Santiago de Compostelausc.gal
Public university in Galicia, Spain, offering diverse academic programs across two campuses with numerous departments and degree options. |
3,872 | |||
| 55 |
HM Hospitaleshmhospitales.com
Private healthcare group with 54 centers offering specialized hospitals, clinics, and integrated care focused on quality, innovation, and patient wellbeing. |
3,803 | |||
| 56 |
Barcelona Children's Hospital Sant Joan de Déusjdhospitalbarcelona.org
A teaching hospital specializing in pediatrics, gynecology, and obstetrics in Barcelona, Catalonia Privately owned, affiliated with the Hospitaller Order of St John of God |
3,728 | |||
| 57 |
Oesiagrupooesia.com
Oesía is a multinational technology consultancy firm with divisions in ICT and security/defense, specializing in projects for clients worldwide Their innovative solutions and services drive value and growth |
3,697 | |||
| 58 |
Hospital del Marhospitaldelmar.cat
Modern general hospital treating medium and high complexity pathologies, affiliated with a university and emphasizing research, located in a diverse, multicultural area |
3,654 | |||
| 59 |
University of Navarraunav.edu
Private research university with global campuses, focusing on academic and personal growth, offering diverse programs, and contributing to medical research and cultural enrichment. |
3,643 | |||
| 60 |
Applus+ Idiadaapplusidiada.com
Global automotive partner providing design, engineering, testing, homologation, and validation services with advanced facilities and expert professionals worldwide. |
3,500 | |||
| 61 |
Universidad de Oviedouniovi.es
Public higher education institution, offers diverse undergraduate and postgraduate programs, including bilingual and Erasmus Mundus degrees, and conducts 80% of regional R&D. |
3,498 | |||
| 62 |
Ingeteamingeteam.com
A global team of over 3,500 experts providing innovative solutions in renewable energy, electric vehicle chargers, green hydrogen production, and water technology |
3,443 | |||
| 63 |
ITP Aeroitpaero.com
A leading aircraft engine and component company developing technology for a sustainable aerospace future, with global facilities and commitment to net zero carbon emissions |
3,345 | |||
| 64 |
Universidad de Córdobauco.es
The University of Cordoba focuses on agricultural, health sciences, humanities, and legal and social sciences education, leading the ceiA3 International Excellence Campus |
3,304 | |||
| 65 |
Hospital Universitario La Pazcomunidad.madrid
A public hospital in Madrid that offers specialized healthcare services to patients from Spain and other countries, with a strong reputation in the healthcare industry |
3,225 | |||
| 66 |
Plexus Techplexus.es
A technology company specializing in various sectors, offering 360º services with a focus on innovation to enhance people's lives |
3,154 | |||
| 67 |
Hospital Gregorio Marañónhggm.es
A public hospital in Madrid known for highly trained professionals, teaching and research, technological advancements, and national/international specialty care |
3,146 | |||
| 68 |
Fluidrafluidra.com
Global leader in pool and wellness equipment, offering innovative products and services in over 45 countries with a trusted brand portfolio |
3,137 | |||
| 69 |
Fundación Hospitalariasfundacionhospitalarias.org
Non-profit institution providing specialized care, assistance, and social reintegration for individuals with mental illness, intellectual disabilities, and other conditions worldwide |
3,112 | |||
| 70 |
Desigualdesigual.com
A fashion company that creates unique pieces for women, men, kids, and accessories, focusing on self-expression through patchwork, textures, and graphic motifs |
3,072 | |||
| 71 |
Navantianavantia.es
Civil and military shipbuilding, ship repairs, turbine manufacturing, engine production, and weapon systems development with centuries of experience. |
2,977 | |||
| 72 |
Universidad Pontificia Comillascomillas.edu
A long-standing university with Jesuit leadership, emphasizing tradition, modern education, and strong connections with business, professional, and social sectors |
2,920 | |||
| 73 |
Hospital de la Santa Creu i Sant Pausantpau.cat
A centuries-old highly complex hospital in Spain, primarily serving Barcelona and Catalonia, with a prominent national and international reputation |
2,826 | |||
| 74 |
Orona Grouporona-group.com
Design manufacture install maintain modernize lifts escalators with innovations in traffic management space optimization comfort safety across Europe. |
2,818 | |||
| 75 |
Factorialfactorialhr.com
A leading HR software for SMEs, automating administrative tasks worldwide Offers solutions like time management, talent management, recruitment, and more |
2,728 | |||
| 76 |
Europastryeuropastry.com
A leading bakery company specializing in frozen doughs for bread, pastries, and snacks, rooted in traditional baking with a strong focus on innovation and sustainability |
2,712 | |||
| 77 |
Exeltisexeltis.com
Innovative global organization in the pharmaceutical sector, committed to improving health through the development and marketing of medicinal products worldwide |
2,659 | |||
| 78 |
Banco de Españabde.es
National central bank and banking supervisor, managing monetary policy, currency issuance, payment systems, and financial system stability in Spain. |
2,585 | |||
| 79 |
CIE Automotivecieautomotive.com
An industrial group specializing in supplying automotive components and subassemblies on a global scale, offering various technologies to meet customer needs |
2,561 | |||
| 80 |
Power Electronicspower-electronics.com
Leading solar inverter manufacturer, energy storage solutions, projects across 36 countries, prevents CO2 emissions, global energy benchmark. |
2,513 | |||
| 81 |
CUPA GROUPcupagroup.com
Leading multinational in natural slate and stone, developing innovative solutions for energy efficiency and sustainability in construction worldwide. |
2,500 | |||
| 82 |
Laboratorios Normonnormon.com
A Spanish pharmaceutical laboratory with over 85 years of experience specializing in high-quality medicines, offering a wide range of products internationally |
2,427 | |||
| 83 |
Almirallalmirall.com
Global biopharmaceutical company focused on medical dermatology, developing innovative solutions for dermatological diseases through R&D, healthcare partnerships, and global presence in 100+ countries |
2,401 | |||
| 84 |
Chemochemopharmaceuticals.com
Specializing in pharmaceutical research, development, manufacturing, and sales worldwide, with a focus on innovation and sustainable development to improve health and quality of life |
2,388 | |||
| 85 |
Clínica Universidad de Navarracun.es
A highly specialized medical center affiliated with the University of Navarra, known for innovative technology, team-based approach, research, teaching, and personalized patient care |
2,347 | |||
| 86 |
Horse Technologieshorse-powertrain.com
Global partner for low-emission powertrain solutions in automotive and industrial sectors, leveraging Renault Group expertise to accelerate decarbonisation with tailored solutions worldwide |
2,327 | |||
| 87 |
ESTEVEesteve.com
International pharmaceutical company focused on improving people's lives through innovative solutions and environmentally sustainable practices, with production sites globally |
2,305 | |||
| 88 |
Universitat de Gironaudg.edu
A public institution in Catalonia focused on teaching, research, and societal development through knowledge creation and dissemination in various fields |
2,304 | |||
| 89 |
bonÀrea Agrupabonarea-agrupa.com
The company specializes in the agri-food sector, handling all aspects from livestock farming to product distribution, ensuring quality, safety, and efficiency |
2,251 | |||
| 90 |
Hospital Universitari de Bellvitgebellvitgehospital.cat
Tertiary-care teaching facility with 700 beds, offering high complexity medical care to over 2 million people, ranked among the top hospitals in the state |
2,231 | |||
| 91 | 2,172 | ||||
| 92 |
University of Deustodeusto.es
A renowned university offering competency-based education, values-driven teaching, specialized research, and an international perspective for over 125 years |
2,169 | |||
| 93 |
Hospital La Fe de Valenciahospital-lafe.com
A leading public healthcare center in Spain's Valencia region, offering comprehensive medical services, teaching programs, and research facilities with over 7,000 staff members |
2,157 | |||
| 94 |
UCAM Universidad Católica San Antonio de Murciaucam.edu
A private university established in 1996, dedicated to educating students, advancing research, and contributing to society and cultural development |
2,116 | |||
| 95 | 2,113 | ||||
| 96 |
Nippon Sanso Europenippongases.com
A leading European company in industrial and medical gases, offering innovative solutions for various industries, prioritizing safety, quality, and sustainability |
2,106 | |||
| 97 | 2,077 | ||||
| 98 |
Hospital Privado Universitario de Córdobahospitalprivado.com.ar
A private university hospital in Córdoba, Argentina, dedicated to providing high-quality medical care, research, and education for over 60 years |
2,041 | |||
| 99 |
MAXAMmaxamcorp.com
Design, development, manufacture of energetic materials including blasting solutions for mining, cartridges for shooting, and defense sector products worldwide. |
2,017 | |||
| 100 |
DR. SCHAR ESPAÑA, SLUdrschaer.com
A global company founded in 1922 in the Alps, committed to improving special nutritional needs with products available in over 100 countries |
2,012 | |||
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How this list is built
Every company on this list has a Tamtam company profile. The industry is the one the company gives on LinkedIn; categories such as SaaS or fintech are classified by Tamtam's AI from the company's website and LinkedIn page; and the headquarters city must match the company's own address. Companies are ranked by the number of employees on LinkedIn, and the list is refreshed every night. Classifications can be wrong, so treat the list as a starting point rather than an official ranking. Last updated Nov 11, 2026.
More company lists in Spain
- The largest companies in Spain 10,893
- Multinational companies in Spain 2,706
- Retail chains in Spain 1,251
- Manufacturers in Spain 1,080
- Wellness and Fitness Services companies in Spain 879
- Healthcare providers in Spain 711
- Companies with a mobile app in Spain 561
- Hotel and hospitality groups in Spain 539
- Family-owned companies in Spain 531
- Software Development companies in Spain 530
- Professional services firms in Spain 522
- Critical infrastructure operators in Spain 517
- IT services companies in Spain 484
- Financial services firms in Spain 482
- Food and Beverage Services companies in Spain 462
- SaaS companies in Spain 445
- Retail Apparel and Fashion companies in Spain 439
- IT Services and IT Consulting companies in Spain 437
- Hospitality companies in Spain 435
- Consulting firms in Spain 420
- E-commerce companies in Spain 416
- Food and beverage companies in Spain 416
- Hardware manufacturers in Spain 415
- Transportation, Logistics, Supply Chain and Storage companies in Spain 397
The same list elsewhere in Spain
- Companies with in-house R&D in Catalonia 324
- Companies with in-house R&D in Community of Madrid 245
- Companies with in-house R&D in Valencian Community 102
- Companies with in-house R&D in Basque Country 99
- Companies with in-house R&D in Andalusia 89
- Companies with in-house R&D in Region of Murcia 25
- Companies with in-house R&D in Madrid 158
- Companies with in-house R&D in Barcelona 122